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Sharon E. Murphy
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Journal Articles

Abstract 232: Genome-wide association study (GWAS) of total nicotine equivalents: A composite biomarker of nicotine uptake

Free
Linda M. Polfus, S. Lani Park, Yesha M. Patel, Sharon E. Murphy, David Conti, Christopher Haiman, Daniel O. Stram, Loïc Le Marchand
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 232.
https://doi.org/10.1158/1538-7445.AM2018-232
Published: 01 July 2018
View articletitled, Abstract 232: Genome-wide association study (GWAS) of total nicotine equivalents: A composite biomarker of nicotine uptake
Journal Articles

Abstract 4347: A randomized phase 2 clinical trial of PEITC on detoxification of tobacco-specific and non-specific carcinogens and toxicants

Free
Jian-Min Yuan, Jian-Min Yuan, Irina Stepanov, Sharon E. Murphy, Sharon E. Murphy, Renwei Wang, Steven G. Carmella, Heather H. Nelson, Heather H. Nelson, Dorothy Hatsukami, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4347.
https://doi.org/10.1158/1538-7445.AM2016-4347
Published: 15 July 2016
View articletitled, Abstract 4347: A randomized phase 2 clinical trial of PEITC on detoxification of tobacco-specific and non-specific carcinogens and toxicants
Journal Articles

Abstract 4595: The impact of CYP2A6 genetic polymorphisms on nicotine metabolism and lung cancer risk in two prospective cohorts of smokers

Free
Jian-Min Yuan, Heather H. Nelson, Lesley M. Butler, Steven G. Carmella, Renwei Wang, Jennifer Adams-Haduch, Stephen S. Hecht, Woon-Puay Koh, Yu-Tang Gao, Sharon E. Murphy
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4595.
https://doi.org/10.1158/1538-7445.AM2015-4595
Published: 01 August 2015
View articletitled, Abstract 4595: The impact of CYP2A6 genetic polymorphisms on nicotine metabolism and lung cancer risk in two prospective cohorts of smokers
Journal Articles

Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers

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Jian-Min Yuan, Yu-Tang Gao, Sharon E. Murphy, Steven G. Carmella, Renwei Wang, Yan Zhong, Kristin A. Moy, Andrew B. Davis, Li Tao, Menglan Chen, Shaomei Han, Heather H. Nelson, Mimi C. Yu, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2011) 71 (21): 6749–6757.
https://doi.org/10.1158/0008-5472.CAN-11-0209
Published: 30 October 2011
View articletitled, Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers
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Journal Articles

Abstract LB-432: Effect of chronic nicotine consumption on NNK-induced lung tumors in the A/J mouse

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Sharon E. Murphy, Linda B. von Weymarn, Melissa M. Schutten, Mitzi Lewellen, Fekadu Kassie, Jaime F. Modiano
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-432.
https://doi.org/10.1158/1538-7445.AM2011-LB-432
Published: 15 April 2011
View articletitled, Abstract LB-432: Effect of chronic nicotine consumption on NNK-induced lung tumors in the A/J mouse
Journal Articles

Abstract 4656: Relationship of nicotine and carcinogen biomarkers to lung cancer risk among smokers in the Shanghai cohort study

Free
Sharon E. Murphy, Jeannette Zinggeler Berg, Renwei Wang, Katherine M. Wickham, Yu-Tang Gao, Stephen S. Hecht, Jian-Min Yuan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4656.
https://doi.org/10.1158/1538-7445.AM2011-4656
Published: 15 April 2011
View articletitled, Abstract 4656: Relationship of nicotine and carcinogen biomarkers to lung cancer risk among smokers in the Shanghai cohort study
Journal Articles

Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

Free
Jian-Min Yuan, Woon-Puay Koh, Sharon E. Murphy, Yunhua Fan, Renwei Wang, Steven G. Carmella, Shaomei Han, Katie Wickham, Yu-Tang Gao, Mimi C. Yu, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2990–2995.
https://doi.org/10.1158/0008-5472.CAN-08-4330
Published: 01 April 2009
View articletitled, Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers
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Journal Articles

Smokers with the CHRNA Lung Cancer–Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

Free
Loïc Le Marchand, Kiersten S. Derby, Sharon E. Murphy, Stephen S. Hecht, Dorothy Hatsukami, Steven G. Carmella, Maarit Tiirikainen, Hansong Wang
Journal: Cancer Research
Cancer Res (2008) 68 (22): 9137–9140.
https://doi.org/10.1158/0008-5472.CAN-08-2271
Published: 14 November 2008
View articletitled, Smokers with the CHRNA Lung Cancer–Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine
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Journal Articles

Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone (NNK) by cytochrome P450 2A13 in human fetal nasal microsomes

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Sharon E. Murphy, Hansen Wong, Xuiling Zhang, Jun Gu, Qing-Yu Zhang, Xinxin Ding
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 497.
Published: 01 May 2005
View articletitled, Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone (NNK) by cytochrome P450 2A13 in human fetal nasal microsomes
Journal Articles

Uptake of nicotine and lung carcinogens in smokers of regular, light, and ultra-light cigarettes

Free
Stephen S. Hecht, Steven G. Carmella, Ky-Anh Le, Sharon E. Murphy, Y. Shelby Li, Chap Le, Joni Jensen, Anne Joseph, Dorothy Hatsukami
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 916.
Published: 01 April 2004
View articletitled, Uptake of nicotine and lung carcinogens in smokers of regular, light, and ultra-light cigarettes
Journal Articles

Quantitation of Urinary Metabolites of a Tobacco-specific Lung Carcinogen after Smoking Cessation

Free
Stephen S. Hecht, Steven G. Carmella, Menglan Chen, J. F. Dor Koch, Andrew T. Miller, Sharon E. Murphy, Joni A. Jensen, Cheryl L. Zimmerman, Dorothy K. Hatsukami
Journal: Cancer Research
Cancer Res (1999) 59 (3): 590–596.
Published: 01 February 1999
View articletitled, Quantitation of Urinary Metabolites of a Tobacco-specific Lung Carcinogen after Smoking Cessation
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Journal Articles

Biomarkers for Human Uptake and Metabolic Activation of Tobacco-specific Nitrosamines

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Stephen S. Hecht, Steven G. Carmella, Peter G. Foiles, Sharon E. Murphy
Journal: Cancer Research
Cancer Res (1994) 54 (7_Supplement): 1912s–1917s.
Published: 01 April 1994
View articletitled, Biomarkers for Human Uptake and Metabolic Activation of Tobacco-specific Nitrosamines
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Journal Articles

Two Types of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Hemoglobin Adducts, from Metabolites Which Migrate into or Are Formed in Red Blood Cells

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Sharon E. Murphy, Kristin A. Coletta
Journal: Cancer Research
Cancer Res (1993) 53 (4): 777–783.
Published: 01 February 1993
View articletitled, Two Types of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Hemoglobin Adducts, from Metabolites Which Migrate into or Are Formed in Red Blood Cells
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Journal Articles

DNA and Hemoglobin Adducts as Markers of Metabolic Activation of Tobacco-specific Carcinogens

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Peter G. Foiles, Sharon E. Murphy, Lisa A. Peterson, Steven G. Carmella, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (1992) 52 (9_Supplement): 2698s–2701s.
Published: 01 May 1992
View articletitled, DNA and Hemoglobin Adducts as Markers of Metabolic Activation of Tobacco-specific Carcinogens
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Journal Articles

Dose-Response Study of DNA and Hemoglobin Adduct Formation by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 Rats

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Sharon E. Murphy, Adrienne Palomino, Stephen S. Hecht, Dietrich Hoffman
Journal: Cancer Research
Cancer Res (1990) 50 (17): 5446–5452.
Published: 01 September 1990
View articletitled, Dose-Response Study of DNA and Hemoglobin Adduct Formation by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 Rats
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Journal Articles

Comparative Metabolism of N′-Nitrosonornicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Cultured F344 Rat Oral Tissue and Esophagus

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Sharon E. Murphy, Rachel Heiblum, Neil Trushin
Journal: Cancer Research
Cancer Res (1990) 50 (15): 4685–4691.
Published: 01 August 1990
View articletitled, Comparative Metabolism of N′-Nitrosonornicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Cultured F344 Rat Oral Tissue and Esophagus
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Journal Articles

Effects of Chronic Ethanol Consumption on Benzo(a)pyrene Metabolism and Glutathione S-Transferase Activities in Syrian Golden Hamster Cheek Pouch and Liver

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Sharon E. Murphy, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (1986) 46 (1): 141–146.
Published: 01 January 1986
View articletitled, Effects of Chronic Ethanol Consumption on Benzo(a)pyrene Metabolism and Glutathione S-Transferase Activities in Syrian Golden Hamster Cheek Pouch and Liver
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