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Sharmila Shankar
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Journal Articles

Abstract 3068: Chronic alcohol exposure induces malignant transformation of pancreatic ductal epithelial cells and generates stem cell characteristics

We Yu, Yiming Ma, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3068.
https://doi.org/10.1158/1538-7445.AM2018-3068
Published: 01 July 2018
View article titled, Abstract 3068: Chronic alcohol exposure induces malignant transformation of pancreatic ductal epithelial cells and generates stem cell characteristics
Journal Articles

Abstract 3728: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in KC and KPC mice

Raj K. Verma, Wei Yu, Anju Shrivastava, Rakesh K. Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3728.
https://doi.org/10.1158/1538-7445.AM2018-3728
Published: 01 July 2018
View article titled, Abstract 3728: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in KC and KPC mice
Journal Articles

Abstract 4509: SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer

Yiming Ma, Wei Yu, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4509.
https://doi.org/10.1158/1538-7445.AM2018-4509
Published: 01 July 2018
View article titled, Abstract 4509: SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer
Journal Articles

Abstract 2074: Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell characteristics by suppressing sonic hedgehog pathway

Wei Yu, Yiming Ma, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2074.
https://doi.org/10.1158/1538-7445.AM2016-2074
Published: 15 July 2016
View article titled, Abstract 2074: Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell characteristics by suppressing sonic hedgehog pathway
Journal Articles

Abstract 4065: Mechanistic role of heavy metal cadmium exposure in the etiology of pancreatic cancer

Wei Yu, Yiming Ma, Rakesh Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4065.
https://doi.org/10.1158/1538-7445.AM2016-4065
Published: 15 July 2016
View article titled, Abstract 4065: Mechanistic role of heavy metal cadmium exposure in the etiology of pancreatic cancer
Journal Articles

Abstract A121: Suppression of orthotopic pancreatic cancer growth by sulforaphane is associated with activation of FOXO transcription factors

Wei Yu, Rakesh Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A121.
https://doi.org/10.1158/1538-7445.PANCA2014-A121
Published: 30 June 2015
View article titled, Abstract A121: Suppression of orthotopic pancreatic cancer growth by sulforaphane is associated with activation of FOXO transcription factors
Journal Articles

Abstract 4123: Exploiting sonic hedgehog pathway in pancreatic carcinogenesis as a potential target for chemoprevention

Rakesh Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4123.
https://doi.org/10.1158/1538-7445.AM2014-4123
Published: 01 October 2014
View article titled, Abstract 4123: Exploiting sonic hedgehog pathway in pancreatic carcinogenesis as a potential target for chemoprevention
Journal Articles

Abstract A45: Resveratrol inhibits prostate cancer stem cell characteristics by suppressing Wnt, sonic hedgehog, and Notch pathways

Rakesh K. Srivastava, Mariana Rodova, Junsheng Fu, Dara Nall, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): A45.
https://doi.org/10.1158/1538-7445.PRCA2012-A45
Published: 09 May 2013
View article titled, Abstract A45: Resveratrol inhibits prostate cancer stem cell characteristics by suppressing Wnt, sonic hedgehog, and Notch pathways
Journal Articles

Abstract 3193: NPV-LDE-225 (Erismodegib) inhibits human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.

Rajesh Nanta, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3193.
https://doi.org/10.1158/1538-7445.AM2013-3193
Published: 15 April 2013
View article titled, Abstract 3193: NPV-LDE-225 (Erismodegib) inhibits human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.
Journal Articles

Abstract 200: EGCG inhibits pancreatic cancer stem cell characteristics in human primary tumors, and carcinogenesis in KrasG12D transgenic mice.

Luke Marsh, Su-Ni Tang, Dara Nall, Chris Jackman, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 200.
https://doi.org/10.1158/1538-7445.AM2013-200
Published: 15 April 2013
View article titled, Abstract 200: EGCG inhibits pancreatic cancer stem cell characteristics in human primary tumors, and carcinogenesis in Kras<sup>G12D</sup> transgenic mice.
Journal Articles

Abstract 3685: Targeting of pancreatic cancer stem cell self-renewal by Sulforaphane involves modulation of Sonic hedgehog signaling.

Rakesh Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3685.
https://doi.org/10.1158/1538-7445.AM2013-3685
Published: 15 April 2013
View article titled, Abstract 3685: Targeting of pancreatic cancer stem cell self-renewal by Sulforaphane involves modulation of Sonic hedgehog signaling.
Journal Articles

Abstract 4012: GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.

Junsheng Fu, Mariana Rodova, Sanjit K. Roy, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4012.
https://doi.org/10.1158/1538-7445.AM2013-4012
Published: 15 April 2013
View article titled, Abstract 4012: GANT-61 inhibits pancreatic cancer stem cell growth i<em>n vitro</em> and in NOD/SCID/IL2R gamma null mice xenograft.
Journal Articles

Abstract 258: Development of death receptor agonists - A novel therapy for breast cancer

Rakesh Srivastava, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 258.
https://doi.org/10.1158/1538-7445.AM2012-258
Published: 15 April 2012
View article titled, Abstract 258: Development of death receptor agonists - A novel therapy for breast cancer
Journal Articles

Abstract 1611: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in BALB/c Nude mice through activation of FKHRL1/FOXO3a transcription factor.

Sharmila Shankar, Luke Marsh, Chris Jackman, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1611.
https://doi.org/10.1158/1538-7445.AM2012-1611
Published: 15 April 2012
View article titled, Abstract 1611: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in BALB/c Nude mice through activation of FKHRL1/FOXO3a transcription factor.
Journal Articles

Abstract 171: EGCG enhances the therapeutic potential of gemcitabine and CP690550 (Tasocitinib) by inhibiting STAT3 signaling pathway in human pancreatic cancer cells

Su-Ni Tang, Junsheng Fu, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 171.
https://doi.org/10.1158/1538-7445.AM2012-171
Published: 15 April 2012
View article titled, Abstract 171: EGCG enhances the therapeutic potential of gemcitabine and CP690550 (Tasocitinib) by inhibiting STAT3 signaling pathway in human pancreatic cancer cells
Journal Articles

Abstract 3306: Screening potential drug candidates for treatment of glioblastoma patients utilizing an in-vivo mouse/ rat model system

Jenna Passarini, John P. Cleary, Preetham Kumar, Trisha Newton, Michael Sharma, Cristian Sharma, Rubio R. Panunzalan, Parkash Gill, Sherven Sharma, Rakesh Srivastava, Sharmila Shankar, Jay P. Sharma
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3306.
https://doi.org/10.1158/1538-7445.AM2011-3306
Published: 15 April 2011
View article titled, Abstract 3306: Screening potential drug candidates for treatment of glioblastoma patients utilizing an in-vivo mouse/ rat model system
Journal Articles

Abstract 4371: Optimal drug concentration screening and evaluation in cancer stem cells & 3D tumor stem cell cultures drug response assays in association with clinical efficacy for melanoma cancer stem cell

Jenna Passarini, John Patrick Cleary, Preetham Kumar, Trisha Newton, Sharmila Shankar, Cristian Sharma, Michael Sharma, Rubio R. Punzalan, Bhuvesh K. Sharma, Sherven Sharma, Parkash Gill, Rakesh K. Srivastava, Jay P. Sharma
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4371.
https://doi.org/10.1158/1538-7445.AM2011-4371
Published: 15 April 2011
View article titled, Abstract 4371: Optimal drug concentration screening and evaluation in cancer stem cells &amp; <sup>3</sup>D tumor stem cell cultures drug response assays in association with clinical efficacy for melanoma cancer stem cell
Journal Articles

Abstract LB-353: Targeting pancreatic cancer stem cells by epigenetic regulation of miR-34a

Sharmila Shankar, Rakesh Srivastava
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-353.
https://doi.org/10.1158/1538-7445.AM2011-LB-353
Published: 15 April 2011
View article titled, Abstract LB-353: Targeting pancreatic cancer stem cells by epigenetic regulation of miR-34a
Journal Articles

Abstract 859: EGCG inhibits pancreatic cancer growth and stem cell characteristics in xenografts and KrasG12D transgenic mice models

Su-Ni Tang, Luke Marsh, Sharmila Shankar, Rakesh K. Srivastava
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 859.
https://doi.org/10.1158/1538-7445.AM2011-859
Published: 15 April 2011
View article titled, Abstract 859: EGCG inhibits pancreatic cancer growth and stem cell characteristics in xenografts and KrasG12D transgenic mice models
Journal Articles

Abstract 754: Development of death receptor agonists for breast cancer therapy

Rakesh K. Srivastava, Chris Jackman, Rachel Davis, Sharmila Shankar
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 754.
https://doi.org/10.1158/1538-7445.AM10-754
Published: 15 April 2010
View article titled, Abstract 754: Development of death receptor agonists for breast cancer therapy