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Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models

Cristina A. Metildi, Sharmeela Kaushal, George A. Luiken, Robert M. Hoffman, Michael Bouvet

Cancer Res (2015) 75 (15_Supplement): 216.

https://doi.org/10.1158/1538-7445.AM2015-216

Published: 01 August 2015

View article titled, Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models

Journal Articles

A Hypusine–eIF5A–PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer

Ken Fujimura, Tracy Wright, Jan Strnadel, Sharmeela Kaushal, Cristina Metildi, Andrew M. Lowy, Michael Bouvet, Jonathan A. Kelber, Richard L. Klemke

Cancer Res (2014) 74 (22): 6671–6681.

https://doi.org/10.1158/0008-5472.CAN-14-1031

Published: 13 November 2014

View article titled, A Hypusine–eIF5A–PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer

Includes: Supplementary data

Journal Articles

Abstract 4960: Serial in vivo orthotopic passage of human pancreatic cancer cells selects for increased stem cell-like behavior

Cristina Metildi, Sharmeela Kaushal, Robert M. Hoffman, Michael Bouvet

Cancer Res (2014) 74 (19_Supplement): 4960.

https://doi.org/10.1158/1538-7445.AM2014-4960

Published: 01 October 2014

View article titled, Abstract 4960: Serial in vivo orthotopic passage of human pancreatic cancer cells selects for increased stem cell-like behavior

Journal Articles

Abstract 4311: Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models

Cristina A. Metildi, Sharmeela Kaushal, Csilla N. Felsen, Quyen T. Nguyen, Robert M. Hoffman, Roger Y. Tsien, Michael Bouvet

Cancer Res (2014) 74 (19_Supplement): 4311.

https://doi.org/10.1158/1538-7445.AM2014-4311

Published: 01 October 2014

View article titled, Abstract 4311: Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models

Journal Articles

Abstract LB-303: A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic ductal adenocarcinoma

Ken Fujimura, Tracy Wright, Jan Strnadel, Jonathan Kelber, Sharmeela Kaushal, Cristina Metildi, Andrew Lowy, Michael Bouvet, Richard Klemke

Cancer Res (2014) 74 (19_Supplement): LB-303.

https://doi.org/10.1158/1538-7445.AM2014-LB-303

Published: 01 October 2014

View article titled, Abstract LB-303: A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic ductal adenocarcinoma

Journal Articles

Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression.

Cristina A. Metildi, Sharmeela Kaushal, Jan Strnadel, Tracy Wright, Jonathan A. Kelber, Richard L. Klemke, Robert M. Hoffman, Michael Bouvet

Cancer Res (2013) 73 (8_Supplement): 4911.

https://doi.org/10.1158/1538-7445.AM2013-4911

Published: 15 April 2013

View article titled, Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression.

Journal Articles

Abstract 4138: Fluorescence laparoscopy with an LED light source enables fluorescence-guided resection of pancreatic cancer, labeled with fluorophore-conjugated antibodies, in mouse models.

Cristina A. Metildi, Sharmeela Kaushal, George A. Luiken, Mark A. Talamini, Robert M. Hoffman, Michael Bouvet

Cancer Res (2013) 73 (8_Supplement): 4138.

https://doi.org/10.1158/1538-7445.AM2013-4138

Published: 15 April 2013

View article titled, Abstract 4138: Fluorescence laparoscopy with an LED light source enables fluorescence-guided resection of pancreatic cancer, labeled with fluorophore-conjugated antibodies, in mouse models.

Journal Articles

Abstract 731: In vivo fluorescence labeling of gastrointestinal stromal tumor (GIST) .

Cristina A. Metildi, Chih-Min Tang, Sharmeela Kaushal, Stephanie Y. Leonard, Paolo Magistri, Robert M. Hoffman, Michael Bouvet, Jason K. Sicklick

Cancer Res (2013) 73 (8_Supplement): 731.

https://doi.org/10.1158/1538-7445.AM2013-731

Published: 15 April 2013

View article titled, Abstract 731: In vivo fluorescence labeling of gastrointestinal stromal tumor (GIST) .

Journal Articles

Abstract 722: Evaluation of a chimeric anti CEA-conjugated antibody with AlexaFlour or Dylight fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models.

Ali A. Maawy, Sharmeela Kaushal, Cynthia S. Snyder, George A. Luiken, Mark A. Talamini, Robert M. Hoffman, Michael Bouvet

Cancer Res (2013) 73 (8_Supplement): 722.

https://doi.org/10.1158/1538-7445.AM2013-722

Published: 15 April 2013

View article titled, Abstract 722: Evaluation of a chimeric anti CEA-conjugated antibody with AlexaFlour or Dylight fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models.

Journal Articles

Abstract 726: Fluorophore-conjugated antibodies improve surgical resection of pancreatic cancer leading to prolonged disease-free survival and overall survival in orthotopic mouse models.

Cristina A. Metildi, Sharmeela Kaushal, Mark A. Talamini, George A. Luiken, Robert M. Hoffman, Michael Bouvet

Cancer Res (2013) 73 (8_Supplement): 726.

https://doi.org/10.1158/1538-7445.AM2013-726

Published: 15 April 2013

View article titled, Abstract 726: Fluorophore-conjugated antibodies improve surgical resection of pancreatic cancer leading to prolonged disease-free survival and overall survival in orthotopic mouse models.

Journal Articles

Abstract 729: Chimeric antibodies to tumor antigen CEA improve detection of human colon cancer for fluorescence-guided surgery.

Cristina A. Metildi, Sharmeela Kaushal, George A. Luiken, Robert M. Hoffman, Michael Bouvet

Cancer Res (2013) 73 (8_Supplement): 729.

https://doi.org/10.1158/1538-7445.AM2013-729

Published: 15 April 2013

View article titled, Abstract 729: Chimeric antibodies to tumor antigen CEA improve detection of human colon cancer for fluorescence-guided surgery.

Journal Articles

KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Jonathan A. Kelber, Theresa Reno, Sharmeela Kaushal, Cristina Metildi, Tracy Wright, Konstantin Stoletov, Jessica M. Weems, Frederick D. Park, Evangeline Mose, Yingchun Wang, Robert M. Hoffman, Andrew M. Lowy, Michael Bouvet, Richard L. Klemke

Cancer Res (2012) 72 (10): 2554–2564.

https://doi.org/10.1158/0008-5472.CAN-11-3552

Published: 14 May 2012

View article titled, KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Includes: Supplementary data

Journal Articles

Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Jonathan A. Kelber, Theresa Reno, Sharmeela Kaushal, Cristina Metildi, Konstantin Stoletov, Jessica Weems, Fred D. Park, Tracy Wright, Evangeline Mose, Robert M. Hoffman, Andrew M. Lowy, Michael M. Bouvet, Richard L. Klemke

Cancer Res (2012) 72 (8_Supplement): 4167.

https://doi.org/10.1158/1538-7445.AM2012-4167

Published: 15 April 2012

View article titled, Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Journal Articles

Abstract 366: Enhanced tumor detection of fluoroscence laparoscopy improves laparoscopic resection of primary pancreatic cancer in mouse models

Cristina A. Metildi, Sharmeela Kaushal, Cynthia S. Snyder, George A. Luiken, Robert M. Hoffman, Michael Bouvet

Cancer Res (2012) 72 (8_Supplement): 366.

https://doi.org/10.1158/1538-7445.AM2012-366

Published: 15 April 2012

View article titled, Abstract 366: Enhanced tumor detection of fluoroscence laparoscopy improves laparoscopic resection of primary pancreatic cancer in mouse models

Journal Articles

Abstract 372: Disease-free survival and overall survival from colon cancer is improved with fluorescence-guided surgery in metastatic mouse models

Cristina A. Metildi Raimo, Sharmeela Kaushal, Cynthia S. Snyder, Robert M. Hoffman, Michael Bouvet

Cancer Res (2012) 72 (8_Supplement): 372.

https://doi.org/10.1158/1538-7445.AM2012-372

Published: 15 April 2012

View article titled, Abstract 372: Disease-free survival and overall survival from colon cancer is improved with fluorescence-guided surgery in metastatic mouse models

Journal Articles

Abstract 375: Fluorescence-guided surgery leads to improved resection of primary pancreatic cancer and prolonged survival

Cristina A. Metildi Raimo, Sharmeela Kaushal, Chanae R. Hardamon, Cynthia S. Snyder, Robert M. Hoffman, Michael Bouvet

Cancer Res (2012) 72 (8_Supplement): 375.

https://doi.org/10.1158/1538-7445.AM2012-375

Published: 15 April 2012

View article titled, Abstract 375: Fluorescence-guided surgery leads to improved resection of primary pancreatic cancer and prolonged survival

Journal Articles

Abstract 5530: Fluorescence laparoscopy improves metastatic detection in both early and advanced colon cancer

Rhiana Menen, Sharmeela Kaushal, Cynthia Snyder, Robert M. Hoffman, Michael Bouvet

Cancer Res (2012) 72 (8_Supplement): 5530.

https://doi.org/10.1158/1538-7445.AM2012-5530

Published: 15 April 2012

View article titled, Abstract 5530: Fluorescence laparoscopy improves metastatic detection in both early and advanced colon cancer

Journal Articles

Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression

Cristina A. Metildi, Sharmeela Kaushal, Jonathan Kelber, Tracy Wright, Cynthia S. Snyder, Richard Klemke, Robert M. Hoffman, Michael Bouvet

Cancer Res (2012) 72 (8_Supplement): 3375.

https://doi.org/10.1158/1538-7445.AM2012-3375

Published: 15 April 2012

View article titled, Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression

Journal Articles

Abstract 514: A novel dual color mouse model for studying the tumor microenvironment of pancreatic adenocarcinoma

Cynthia S. Snyder, Sharmeela Kaushal, Chanae R. Hardamon, Hop S. Tran Cao, Rhiana S. Menen, Cristina A. Metildi, Andrew M. Lowy, Robert M. Hoffman, Michael Bouvet

Cancer Res (2011) 71 (8_Supplement): 514.

https://doi.org/10.1158/1538-7445.AM2011-514

Published: 15 April 2011

View article titled, Abstract 514: A novel dual color mouse model for studying the tumor microenvironment of pancreatic adenocarcinoma

Journal Articles

Abstract 547: A function-blocking monoclonal antibody directed against the collagen-binding α₂ integrin subunit inhibits primary tumor growth and metastasis in a fluorescent orthotopic mouse model of pancreatic cancer

John J. Grzesiak, Hop S. Tran Cao, Sharmeela Kaushal, Robert M. Hoffman, Michael Bouvet

Cancer Res (2011) 71 (8_Supplement): 547.

https://doi.org/10.1158/1538-7445.AM2011-547

Published: 15 April 2011

View article titled, Abstract 547: A function-blocking monoclonal antibody directed against the collagen-binding α2 integrin subunit inhibits primary tumor growth and metastasis in a fluorescent orthotopic mouse model of pancreatic cancer

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Abstract 216: Pancreatic cancer fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA) improves surgical resection and increases disease-free and overall survival in orthotopic mouse models

A Hypusine–eIF5A–PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer

Abstract 4960: Serial in vivo orthotopic passage of human pancreatic cancer cells selects for increased stem cell-like behavior

Abstract 4311: Fluorescence-guided surgery of pancreatic cancer using activatable cell penetrating peptides (ACPPs) in orthotopic mouse models

Abstract LB-303: A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic ductal adenocarcinoma

Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression.

Abstract 4138: Fluorescence laparoscopy with an LED light source enables fluorescence-guided resection of pancreatic cancer, labeled with fluorophore-conjugated antibodies, in mouse models.

Abstract 731: In vivo fluorescence labeling of gastrointestinal stromal tumor (GIST) .

Abstract 722: Evaluation of a chimeric anti CEA-conjugated antibody with AlexaFlour or Dylight fluorescent dyes for imaging pancreatic cancer in orthotopic nude mouse models.

Abstract 726: Fluorophore-conjugated antibodies improve surgical resection of pancreatic cancer leading to prolonged disease-free survival and overall survival in orthotopic mouse models.

Abstract 729: Chimeric antibodies to tumor antigen CEA improve detection of human colon cancer for fluorescence-guided surgery.

KRas Induces a Src/PEAK1/ErbB2 Kinase Amplification Loop That Drives Metastatic Growth and Therapy Resistance in Pancreatic Cancer

Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance

Abstract 366: Enhanced tumor detection of fluoroscence laparoscopy improves laparoscopic resection of primary pancreatic cancer in mouse models

Abstract 372: Disease-free survival and overall survival from colon cancer is improved with fluorescence-guided surgery in metastatic mouse models

Abstract 375: Fluorescence-guided surgery leads to improved resection of primary pancreatic cancer and prolonged survival

Abstract 5530: Fluorescence laparoscopy improves metastatic detection in both early and advanced colon cancer

Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression

Abstract 514: A novel dual color mouse model for studying the tumor microenvironment of pancreatic adenocarcinoma

Abstract 547: A function-blocking monoclonal antibody directed against the collagen-binding α₂ integrin subunit inhibits primary tumor growth and metastasis in a fluorescent orthotopic mouse model of pancreatic cancer

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