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Shar-yin N. Huang
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Journal Articles

SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243

Yasuhisa Murai, Ukhyun Jo, Junko Murai, Lisa M. Jenkins, Shar-Yin N. Huang, Sirisha Chakka, Lu Chen, Ken Cheng, Shinsaku Fukuda, Naoko Takebe, Yves Pommier
Journal: Cancer Research
Cancer Res (2021) 81 (11): 3067–3078.
https://doi.org/10.1158/0008-5472.CAN-20-2694
Published: 01 June 2021
View article titled, SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243
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Includes: Supplementary data
Journal Articles

Abstract LB-121: The novel ATR inhibitor M4344 and CHK1 inhibitor SRA737 overcome chemoresistance in SLFN11-negative cells in combination treatment with DNA-damaging agents

Ukhyun Jo, Yasuhisa Murai, Junko Murai, Shar‐yin N Huang, Sirisha Chakka, Lu Chen, Ken Cheng, Yves Pommier
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-121.
https://doi.org/10.1158/1538-7445.AM2020-LB-121
Published: 15 August 2020
View article titled, Abstract LB-121: The novel ATR inhibitor M4344 and CHK1 inhibitor SRA737 overcome chemoresistance in SLFN11-negative cells in combination treatment with DNA-damaging agents
Journal Articles

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

Junko Murai, Shar-yin N. Huang, Benu Brata Das, Amelie Renaud, Yiping Zhang, James H. Doroshow, Jiuping Ji, Shunichi Takeda, Yves Pommier
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5588–5599.
https://doi.org/10.1158/0008-5472.CAN-12-2753
Published: 31 October 2012
View article titled, Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
Open the PDF for Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors in another window
Includes: Supplementary data