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Shantu G. Amin
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Journal Articles

Abstract 1748: Mcl-1 inhibitor KS18 overcomes bortezomib, venetoclax, and ABT-737 resistance in multiple myeloma

Free
Omar S. Al Odat, Krishne Gowda, Shantu G. Amin, Tulin Budak- Alpdogan, Subash C. Jonnalagadda, Manoj K. Pandey
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1748.
https://doi.org/10.1158/1538-7445.AM2023-1748
Published: 04 April 2023
View articletitled, Abstract 1748: Mcl-1 inhibitor KS18 overcomes bortezomib, venetoclax, and ABT-737 resistance in multiple myeloma
Journal Articles

Abstract 3952: A novel Mcl-1 inhibitor induces cells death in a caspase-dependent manner and increases the efficacies of Venetoclax and ABT-737 in multiple myeloma cells

Free
Omar S. Al-Odat, Rahul S. Tripathi, Sandeep K. Srivastava, Krishne Gowda, Shantu G. Amin, Tulin Budak-Alpdogan, Subash C. Jonnalagadda, Manoj K. Pandey
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3952.
https://doi.org/10.1158/1538-7445.AM2022-3952
Published: 15 June 2022
View articletitled, Abstract 3952: A novel Mcl-1 inhibitor induces cells death in a caspase-dependent manner and increases the efficacies of Venetoclax and ABT-737 in multiple myeloma cells
Journal Articles

Abstract 2806: Inhibition of melanoma development by Isatin analogs

Free
Dhimant H. Desai, Raghvendra Gowda, Krishne Gowda, Saketh S. Dinavahi, Gavin P. Robertson, Shantu G. Amin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2806.
https://doi.org/10.1158/1538-7445.AM2018-2806
Published: 01 July 2018
View articletitled, Abstract 2806: Inhibition of melanoma development by Isatin analogs
Journal Articles

Abstract 1126: Potent inhibition of HCMV by modulating the cellular SNARE syntaxin 5

Free
Dhimant H. Desai, Linda Cruz, Nicholas T. Streck, Trisha D. Desai, Aron Lukacher, Shantu G. Amin, Nicholas J. Buchkovich
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1126.
https://doi.org/10.1158/1538-7445.AM2017-1126
Published: 01 July 2017
View articletitled, Abstract 1126: Potent inhibition of HCMV by modulating the cellular SNARE syntaxin 5
Journal Articles

Abstract 4732: A novel analog of Leonurine inhibits melanoma growth and survival through STAT3 signaling pathways

Free
Manoj K. Pandey, Jacek Krzeminski, Deepkamal Karelia, Arun K. Sharma, Shantu G. Amin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4732.
https://doi.org/10.1158/1538-7445.AM2016-4732
Published: 15 July 2016
View articletitled, Abstract 4732: A novel analog of Leonurine inhibits melanoma growth and survival through STAT3 signaling pathways
Journal Articles

Abstract 4805: In vitro characterization of novel inhibitors of ROCK and MRCK kinases as anticancer agents

Free
Dhimant H. Desai, Vijay P. Kale, Jeremy A. Hengst, Taryn E. Dick, Ashley L. Colledge, Shantu G. Amin, Jong K. Yun
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4805.
https://doi.org/10.1158/1538-7445.AM2016-4805
Published: 15 July 2016
View articletitled, Abstract 4805: In vitro characterization of novel inhibitors of ROCK and MRCK kinases as anticancer agents
Journal Articles

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung

Free
Shuguang Leng, Guodong Wu, Leonard B. Collins, Cynthia L. Thomas, Carmen S. Tellez, Andrew R. Jauregui, Maria A. Picchi, Xiequn Zhang, Daniel E. Juri, Dhimant Desai, Shantu G. Amin, Richard E. Crowell, Christine A. Stidley, Yushi Liu, James A. Swenberg, Yong Lin, Marc G. Wathelet, Frank D. Gilliland, Steven A. Belinsky
Journal: Cancer Research
Cancer Res (2015) 75 (15): 3108–3117.
https://doi.org/10.1158/0008-5472.CAN-15-0243
Published: 02 August 2015
View articletitled, Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung
Open the PDF for Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung in another window
Includes: Supplementary data
Journal Articles

Abstract 2159: Ikaros and Casein kinase II (CK2) regulate PI3K pathway in pediatric leukemia

Free
Chandrika Gowda, Chunhua Song, Yali Ding, Sunil Muthusami, Xiaokang Pan, Dhimant Desai, Shantu G. Amin, Kimberly J. Payne, Sinisa Dovat
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2159.
https://doi.org/10.1158/1538-7445.AM2015-2159
Published: 01 August 2015
View articletitled, Abstract 2159: Ikaros and Casein kinase II (CK2) regulate PI3K pathway in pediatric leukemia
Journal Articles

Abstract 4467: Targeting of chemokine receptor CXCR4 inhibits invasion and sensitizes melanoma cells to chemotherapeutic agents

Free
Manoj K. Pandey, Deepkamal Karelia, Vijay P. Kale, Krishne Gowda, Arun K. Sharma, Rogerio I. Neves, Shantu G. Amin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4467.
https://doi.org/10.1158/1538-7445.AM2015-4467
Published: 01 August 2015
View articletitled, Abstract 4467: Targeting of chemokine receptor CXCR4 inhibits invasion and sensitizes melanoma cells to chemotherapeutic agents
Journal Articles

Abstract 2734: Ethanol potentiates tobacco smoke carcinogens-induced MAPK activation

Free
Manoj K. Pandey, Jagat J. Mukherjee, Dhimant H. Desai, Shantu G. Amin, Subodh Kumar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2734.
https://doi.org/10.1158/1538-7445.AM2015-2734
Published: 01 August 2015
View articletitled, Abstract 2734: Ethanol potentiates tobacco smoke carcinogens-induced MAPK activation
Journal Articles

Abstract 1639: Development of novel thiobarbituric acid derivatives as potential cancer therapeutics

Free
Srinivasa R. Ramisetti, Sang Y. Lee, Manoj K. Pandey, Shantu G. Amin, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1639.
https://doi.org/10.1158/1538-7445.AM2014-1639
Published: 01 October 2014
View articletitled, Abstract 1639: Development of novel thiobarbituric acid derivatives as potential cancer therapeutics
Journal Articles

Abstract 5539: Therapeutic efficacy of novel selenium-containing HDACi in acute leukemia

Free
Mansi Sachdev, Dhimant Desai, Sunil Muthusami, Chandrika Gowda, Chunhua Song, Shantu G. Amin, Sinisa Dovat
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5539.
https://doi.org/10.1158/1538-7445.AM2014-5539
Published: 01 October 2014
View articletitled, Abstract 5539: Therapeutic efficacy of novel selenium-containing HDACi in acute leukemia
Journal Articles

Abstract 3786: Gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma

Free
Manoj K. Pandey, Vijay P. Kale, Chunhua Song, Shen-shu Sung, Arun K. Sharma, Sinisa Dovat, Shantu G. Amin
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3786.
https://doi.org/10.1158/1538-7445.AM2014-3786
Published: 01 October 2014
View articletitled, Abstract 3786: Gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma
Journal Articles

Abstract 4628: PBISe, an iNOS/Akt inhibitor for colon cancer chemoprevention

Free
Dhimant H. Desai, Rosalyn Irby, Cesar Aliaga, Shantu G. Amin
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4628.
https://doi.org/10.1158/1538-7445.AM2011-4628
Published: 15 April 2011
View articletitled, Abstract 4628: PBISe, an iNOS/Akt inhibitor for colon cancer chemoprevention
Journal Articles

Inhibition of Lung Carcinogenesis by Black Tea in Fischer Rats Treated with a Tobacco-specific Carcinogen: Caffeine as an Important Constituent

Free
Fung-Lung Chung, Mingyao Wang, Abraham Rivenson, Michael J. Iatropoulos, Joel C. Reinhardt, Brian Pittman, Chi-Tang Ho, Shantu G. Amin
Journal: Cancer Research
Cancer Res (1998) 58 (18): 4096–4101.
Published: 01 September 1998
View articletitled, Inhibition of Lung Carcinogenesis by Black Tea in Fischer Rats Treated with a Tobacco-specific Carcinogen: Caffeine as an Important Constituent
Open the PDF for Inhibition of Lung Carcinogenesis by Black Tea in Fischer Rats Treated with a Tobacco-specific Carcinogen: Caffeine as an Important Constituent in another window
Journal Articles

Structure-Activity Relationships of Isothiocyanates as Mechanism-based Inhibitors of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis in A/J Mice

Free
Ding Jiao, Karin I. Eklind, Chang-In Choi, Dhimant H. Desai, Shantu G. Amin, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (1994) 54 (16): 4327–4333.
Published: 01 August 1994
View articletitled, Structure-Activity Relationships of Isothiocyanates as Mechanism-based Inhibitors of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis in A/J Mice
Open the PDF for Structure-Activity Relationships of Isothiocyanates as Mechanism-based Inhibitors of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis in A/J Mice in another window
Journal Articles

Inhibition of Tobacco-specific Nitrosamine-induced Lung Tumorigenesis in A/J Mice by Green Tea and Its Major Polyphenol as Antioxidants

Free
Yong Xu, Chi-Tang Ho, Shantu G. Amin, Chi Han, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (1992) 52 (14): 3875–3879.
Published: 01 July 1992
View articletitled, Inhibition of Tobacco-specific Nitrosamine-induced Lung Tumorigenesis in A/J Mice by Green Tea and Its Major Polyphenol as Antioxidants
Open the PDF for Inhibition of Tobacco-specific Nitrosamine-induced Lung Tumorigenesis in A/J Mice by Green Tea and Its Major Polyphenol as Antioxidants in another window
Journal Articles

Structure-Activity Relationships for Inhibition of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Lung Tumorigenesis by Arylalkyl Isothiocyanates in A/J Mice

Free
Mark A. Morse, Karin I. Eklind, Stephen S. Hecht, Kevin G. Jordan, Chang-In Choi, Dhimant H. Desai, Shantu G. Amin, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (1991) 51 (7): 1846–1850.
Published: 01 April 1991
View articletitled, Structure-Activity Relationships for Inhibition of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Lung Tumorigenesis by Arylalkyl Isothiocyanates in A/J Mice
Open the PDF for Structure-Activity Relationships for Inhibition of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Lung Tumorigenesis by Arylalkyl Isothiocyanates in A/J Mice in another window
Journal Articles

Effects of Indole-3-carbinol on Lung Tumorigenesis and DNA Methylation Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the Metabolism and Disposition of NNK in A/J Mice

Free
Mark A. Morse, Susan D. LaGreca, Shantu G. Amin, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (1990) 50 (9): 2613–2617.
Published: 01 May 1990
View articletitled, Effects of Indole-3-carbinol on Lung Tumorigenesis and DNA Methylation Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the Metabolism and Disposition of NNK in A/J Mice
Open the PDF for Effects of Indole-3-carbinol on Lung Tumorigenesis and DNA Methylation Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the Metabolism and Disposition of NNK in A/J Mice in another window
Journal Articles

Effects of Aromatic Isothiocyanates on Tumorigenicity, O6-Methylguanine Formation, and Metabolism of the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J Mouse Lung

Free
Mark A. Morse, Shantu G. Amin, Stephen S. Hecht, Fung-Lung Chung
Journal: Cancer Research
Cancer Res (1989) 49 (11): 2894–2897.
Published: 01 June 1989
View articletitled, Effects of Aromatic Isothiocyanates on Tumorigenicity, O6-Methylguanine Formation, and Metabolism of the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J Mouse Lung
Open the PDF for Effects of Aromatic Isothiocyanates on Tumorigenicity, O6-Methylguanine Formation, and Metabolism of the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J Mouse Lung in another window