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Journal Articles

Abstract 7227: Isatin analogs potentiate the cytotoxicity of venetoclax in acute myeloid leukemia cells

Upendarrao Golla, Satyam Patel, Jeremy Hengst, Charyguly Annageldiyev, Joseph Schramm, Shantu Amin, Dhimant Desai, David Claxton, Sinisa Dovat, Arati Sharma
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7227.
https://doi.org/10.1158/1538-7445.AM2024-7227
Published: 22 March 2024
View articletitled, Abstract 7227: Isatin analogs potentiate the cytotoxicity of venetoclax in acute myeloid leukemia cells
Journal Articles

Abstract 2677: ROCK inhibitors synergize with the BCL2 inhibitor venetoclax for treatment of AML

Upendarrao Golla, Satyam Patel, Diwakar B. Tukaramrao, Jeremy Hengst, Juliana Restrepo, Shantu Amin, Dhimant Desai, Sinisa Dovat, David Claxton, Arati Sharma
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2677.
https://doi.org/10.1158/1538-7445.AM2023-2677
Published: 04 April 2023
View articletitled, Abstract 2677: ROCK inhibitors synergize with the BCL2 inhibitor venetoclax for treatment of AML
Journal Articles

Abstract 3337: The impact of black raspberry as a whole food approach on DNA damage-induced by tobacco carcinogens in the oral cavity and urine of smokers

Kun-Ming Chen, Yuan-Wan Sun, Nicolle M. Krebs, Lisa Reinhart, Dongxiao Sun, Elizabeth P. Bond, Jacek Krzeminski, Krishne Gowda, Shantu Amin, Susan Mallery, John P. Richie, Karam El-Bayoumy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3337.
https://doi.org/10.1158/1538-7445.AM2023-3337
Published: 04 April 2023
View articletitled, Abstract 3337: The impact of black raspberry as a whole food approach on DNA damage-induced by tobacco carcinogens in the oral cavity and urine of smokers
Journal Articles

Abstract 1650: Discovery of a novel Kevetrin analog as a potential therapeutic for ovarian cancer

Asif Raza, Jacek Krzeminski, Shantu Amin, Arun Sharma
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1650.
https://doi.org/10.1158/1538-7445.AM2023-1650
Published: 04 April 2023
View articletitled, Abstract 1650: Discovery of a novel Kevetrin analog as a potential therapeutic for ovarian cancer
Journal Articles

Drug-Tolerant Persister Cells in Cancer Therapy Resistance

Pavan Kumar Dhanyamraju, Todd D. Schell, Shantu Amin, Gavin P. Robertson
Journal: Cancer Research
Cancer Res (2022) 82 (14): 2503–2514.
https://doi.org/10.1158/0008-5472.CAN-21-3844
Published: 18 July 2022
View articletitled, Drug-Tolerant Persister Cells in Cancer Therapy Resistance
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Journal Articles

Abstract 5452: Discovery of a novel seleno-leonurine analog as a potential therapeutic for ovarian cancer

Asif Raza, Jacek Krzeminski, Shantu Amin, Arun Sharma
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5452.
https://doi.org/10.1158/1538-7445.AM2022-5452
Published: 15 June 2022
View articletitled, Abstract 5452: Discovery of a novel seleno-leonurine analog as a potential therapeutic for ovarian cancer
Journal Articles

Abstract 6247: Evaluation of AS-10, identified based on SAR studies of newly generated organoselenium compounds, as a potential colorectal cancer therapeutic acting potentially by acetylating histones

Hannah Johnson, Amandeep Singh, Asif Raza, Deepkamal Karelia, Daniel Plano, Shantu Amin, Arun Sharma
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6247.
https://doi.org/10.1158/1538-7445.AM2022-6247
Published: 15 June 2022
View articletitled, Abstract 6247: Evaluation of AS-10, identified based on SAR studies of newly generated organoselenium compounds, as a potential colorectal cancer therapeutic acting potentially by acetylating histones
Journal Articles

Abstract 2596: Stage-specific inhibition of NNK-induced lung carcinogenesis by 1,4-phenylenebis(methylene)seleno-aspirin (p-XS-Asp)

Asif Raza, Amandeep Singh, Cesar Aliaga, Daniel Plano, Shantu Amin, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2596.
https://doi.org/10.1158/1538-7445.AM2021-2596
Published: 01 July 2021
View articletitled, Abstract 2596: Stage-specific inhibition of NNK-induced lung carcinogenesis by 1,4-phenylenebis(methylene)seleno-aspirin (p-XS-Asp)
Journal Articles

Abstract 2794: A novel bis-aspirinyl selenazolidine compound AS-10 as potential colon cancer therapeutic

Deepkamal N. Karelia, Manoj Pandey, Daniel Plano, Shantu Amin, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2794.
https://doi.org/10.1158/1538-7445.AM2018-2794
Published: 01 July 2018
View articletitled, Abstract 2794: A novel bis-aspirinyl selenazolidine compound AS-10 as potential colon cancer therapeutic
Journal Articles

Abstract 1253: Dissecting the signaling cascades involved in growth inhibition and apoptosis of prostate cancer cells exposed to a novel bis-aspirinyl selenazolidine AS-10

Deepkamal N. Karelia, Sangyub Kim, Srinivasa Ramisetti, Cheng Jiang, Shantu Amin, Arun K. Sharma, Junxuan Lu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1253.
https://doi.org/10.1158/1538-7445.AM2018-1253
Published: 01 July 2018
View articletitled, Abstract 1253: Dissecting the signaling cascades involved in growth inhibition and apoptosis of prostate cancer cells exposed to a novel bis-aspirinyl selenazolidine AS-10
Journal Articles

Abstract 1252: RNA-Seq transcriptome analyses of human LNCaP prostate cancer cells treated with a novel bis-aspirinyl selenazolidine AS-10

Sangyub Kim, Deepkamal N. Karelia, Yuka Imamura, Srinivasa Ramisetti, Cheng Jiang, Shantu Amin, Arun K. Sharma, Junxuan Lu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1252.
https://doi.org/10.1158/1538-7445.AM2018-1252
Published: 01 July 2018
View articletitled, Abstract 1252: RNA-Seq transcriptome analyses of human LNCaP prostate cancer cells treated with a novel bis-aspirinyl selenazolidine AS-10
Journal Articles

Abstract 274: Selective chemopreventive efficacy of 1,4-phenylenebis(methylene)seleno-aspirin (p-XS-Asp) towards lung cancer

Daniel Plano, Srinivasa Ramisetti, Sang-Yub Kim, Manoj Pandey, Cesar Aliaga, Deepkamal N. Karelia, Arthur Berg, Carmen Sanmartin, Junxuan Lu, Shantu Amin, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 274.
https://doi.org/10.1158/1538-7445.AM2018-274
Published: 01 July 2018
View articletitled, Abstract 274: Selective chemopreventive efficacy of 1,4-phenylenebis(methylene)seleno-aspirin (p-XS-Asp) towards lung cancer
Journal Articles

Abstract 795: Isatin analog for the treatment of acute myeloid leukemia

Krishne Gowda, Charyguly Annageldiyev, Dhimant Desai, Shantu Amin, David Claxton, Arati Sharma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 795.
https://doi.org/10.1158/1538-7445.AM2018-795
Published: 01 July 2018
View articletitled, Abstract 795: Isatin analog for the treatment of acute myeloid leukemia
Journal Articles

Abstract LB-266: Identification of novel checkpoint kinase inhibitor ASR352 with selective activity against 5-FU resistant colorectal cancer cells

Srinivasa Ramisetti, Sangyub Kim, Deepkamal Karelia, Junxuan Lu, Shantu Amin, Satya Narayan, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-266.
https://doi.org/10.1158/1538-7445.AM2018-LB-266
Published: 01 July 2018
View articletitled, Abstract LB-266: Identification of novel checkpoint kinase inhibitor ASR352 with selective activity against 5-FU resistant colorectal cancer cells
Journal Articles

Abstract 2237: Novel selenium-containing aspirin molecule AS-10 suppresses androgen receptor signaling and induces apoptosis of LNCap prostate cancer cells

Deepkamal N. Karelia, Sangyub Kim, Srinivasa Ramisetti, Cheng Jiang, Shantu Amin, Arun K. Sharma, Junxuan Lu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2237.
https://doi.org/10.1158/1538-7445.AM2017-2237
Published: 01 July 2017
View articletitled, Abstract 2237: Novel selenium-containing aspirin molecule AS-10 suppresses androgen receptor signaling and induces apoptosis of LNCap prostate cancer cells
Journal Articles

Abstract 1166: Identification of a novel quinoxaline-isoselenourea targeting STAT3 pathway as a potential melanoma therapeutic

Verónica Alcolea, Deepkamal Karelia, Manoj K. Pandey, Daniel Plano, Parvesh Singh, Rosalyn B. Irby, Juan Palop, Shantu Amin, Carmen Sanmartín, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1166.
https://doi.org/10.1158/1538-7445.AM2017-1166
Published: 01 July 2017
View articletitled, Abstract 1166: Identification of a novel quinoxaline-isoselenourea targeting STAT3 pathway as a potential melanoma therapeutic
Journal Articles

Abstract 2240: “Smart” selenium compound ISC-4 inhibits androgen receptor signaling and induces ROS- and p53-dependent apoptosis in LNCaP prostate cancer cells

Wei Wu, Kartick Pramanik, Cheng Jiang, Shantu Amin, Arun K. Sharma, Junxuan Lu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2240.
https://doi.org/10.1158/1538-7445.AM2017-2240
Published: 01 July 2017
View articletitled, Abstract 2240: “Smart” selenium compound ISC-4 inhibits androgen receptor signaling and induces ROS- and p53-dependent apoptosis in LNCaP prostate cancer cells
Journal Articles

Abstract 503: Enhanced repair of bulky DNA adducts induced by a tobacco carcinogen and UV light in human oral epithelial cells by black raspberry extract

Joseph B. Guttenplan, Kun-Ming Chen, Yuan-Wan Sun, Ross Teicher, Wieslawa Kosinska, Krishne Gowda, Shantu Amin, Gary D. Stoner, Karam El-Bayoumy
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 503.
https://doi.org/10.1158/1538-7445.AM2017-503
Published: 01 July 2017
View articletitled, Abstract 503: Enhanced repair of bulky DNA adducts induced by a tobacco carcinogen and UV light in human oral epithelial cells by black raspberry extract
Journal Articles

Abstract 3061: AS-10: a new small molecule with promising activity against pancreatic cancer

Deepkamal Karelia, Manoj K. Pandey, Daniel Plano, Shantu Amin, Arun K. Sharma
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3061.
https://doi.org/10.1158/1538-7445.AM2016-3061
Published: 15 July 2016
View articletitled, Abstract 3061: AS-10: a new small molecule with promising activity against pancreatic cancer
Journal Articles

Abstract 4454: Genome-wide analysis of DNA methylation induced by environmental carcinogen dibenzo[def,p]chrysene in ovarian tissues of mice

Yuan-Wan Sun, Karam El-Bayoumy, Yuka Imamura Kawasawa, Anna Salzberg, Cesar Aliaga, Krishnegowda Gowdahalli, Shantu Amin, Kun-Ming Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4454.
https://doi.org/10.1158/1538-7445.AM2016-4454
Published: 15 July 2016
View articletitled, Abstract 4454: Genome-wide analysis of DNA methylation induced by environmental carcinogen dibenzo[def,p]chrysene in ovarian tissues of mice