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Journal Articles

Abstract 5727: ISM9682A, a novel and potent KIF18A inhibitor, shows robust antitumor effects against chromosomally unstable cancers

Jie Zhang, Feng Gao, Wei Zhu, Chenxi Xu, Xiaoyu Ding, Jing Shang, Junwen Qiao, Shan Chen, Xin Cai, Xiao Ding, Supriya Bavadekar, Sujata Rao, Man Zhang, Feng Ren, Alex Zhavoronkov
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5727.
https://doi.org/10.1158/1538-7445.AM2024-5727
Published: 22 March 2024
View articletitled, Abstract 5727: ISM9682A, a novel and potent KIF18A inhibitor, shows robust antitumor effects against chromosomally unstable cancers
Journal Articles

Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer

Qingyuan Meng, Xiao Ding, Xiaosong Liu, Hailong Wang, Ling Wang, Junwen Qiao, Hua Cao, Yushu Yin, Congcong Zhu, Xing Liang, Xin Cai, Yuanyuan Xu, Chenxi Xu, Shan Chen, Sujata Rao, Feng Ren, Alex Zhavoronkov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 503.
https://doi.org/10.1158/1538-7445.AM2023-503
Published: 04 April 2023
View articletitled, Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer
Journal Articles

PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma

Jun-Cheng Wang, Dong-Ping Chen, Shi-Xun Lu, Jin-Bin Chen, Yuan Wei, Xue-Chao Liu, Yu-Hao Tang, Rongxin Zhang, Jian-Cong Chen, Anna Kan, Li Xu, Yao-Jun Zhang, Jiajie Hou, Dong-Ming Kuang, Min-Shan Chen, Zhong-Guo Zhou
Journal: Cancer Research
Cancer Res (2022) 82 (18): 3307–3320.
https://doi.org/10.1158/0008-5472.CAN-21-3899
Published: 16 September 2022
View articletitled, PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma
Open the PDF for PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract CT406: Patients with cancer appear more vulnerable to SARS-COV-2: A multi-center study during the COVID-19 outbreak

Meng-Yuan Dai, Dian-bo Liu, Miao Liu, Fu-Xiang Zhou, Gui-Ling Li, Zhen Chen, Zhi-An Zhang, Hua-You Md, Meng Wu, Qi-Chao Zheng, Yong Xiong, Hui-Hua Xiong, Chun Wang, Chang-Chun Chen, Fei Xiong, Yan Zhang, Ya-Qin Peng, Si-Ping Ge, Bo Zhen, Ting-Ting Yu, Ling Wang, Hua Wang, Yu Liu, Ye-Shan Chen, Jun-Hua Mei, Xiao-Jia Gao, Zhu-Yan Li, Li-Juan Gan, Can He, Zhen Li, Yu-Ying Shi, Yu-Wen Qi, Jing Yang, Daniel G. Tenen, Li Chai, Lorelei Ann Mucci, Mauricio Santillana, Hongbing Cai
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT406.
https://doi.org/10.1158/1538-7445.AM2020-CT406
Published: 15 August 2020
View articletitled, Abstract CT406: Patients with cancer appear more vulnerable to SARS-COV-2: A multi-center study during the COVID-19 outbreak
Journal Articles

Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis

Shenglan Shang, Xinran Ji, Lili Zhang, Jun Chen, Chuan Li, Rongchen Shi, Wei Xiang, Xia Kang, Dapeng Zhang, Fan Yang, Rongyang Dai, Peng Chen, Shan Chen, Yongchuan Chen, Yongsheng Li, Hongming Miao
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5513–5526.
https://doi.org/10.1158/0008-5472.CAN-19-1059
Published: 01 November 2019
View articletitled, Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis
Open the PDF for Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 1501: Aberrant JAK/STAT signaling orchestrates global promoter methylation and promotes TGF-β mediated EMT through epigenetic silencing of miR-193a in gastric cancer

Jora M.j. Lin, Jiang-Liang Chou, David E. Frankhouser, Yu-Ming Chuang, Alex Liang-Yu Chang, Li-Han Zeng, Szu-Shan Chen, Ru-Inn Lin, Cheng-Shyong Wu, Kuo-Liang Wei, Enders K.W. Ng, Pearlly S. Yan, Alfred S.L. Cheng, Chin Li, Michael W. Y. Chan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1501.
https://doi.org/10.1158/1538-7445.AM2016-1501
Published: 15 July 2016
View articletitled, Abstract 1501: Aberrant JAK/STAT signaling orchestrates global promoter methylation and promotes TGF-β mediated EMT through epigenetic silencing of miR-193a in gastric cancer
Journal Articles

Abstract 2012: SPDEF enforces tumor quiescence by shifting the transcriptional targets of activated β-catenin

Yuan-Hung Lo, Taeko Noah, Min-Shan Chen, Winnie Zou, Noah Shroyer
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2012.
https://doi.org/10.1158/1538-7445.AM2016-2012
Published: 15 July 2016
View articletitled, Abstract 2012: SPDEF enforces tumor quiescence by shifting the transcriptional targets of activated β-catenin
Journal Articles

Abstract 442: Decreased tumor progression by the knockdown of interleukin 17 receoptor A in the B16F10 melanoma model

Ya-Shan Chen, Chao-Lin Liu, Hui-Shan Chen, Su-Ting Wu, Chia-Rui Shen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 442.
https://doi.org/10.1158/1538-7445.AM2015-442
Published: 01 August 2015
View articletitled, Abstract 442: Decreased tumor progression by the knockdown of interleukin 17 receoptor A in the B16F10 melanoma model
Journal Articles

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation

Shih-Hwa Chiou, Mong-Lien Wang, Yu-Ting Chou, Chi-Jen Chen, Chun-Fu Hong, Wang-Ju Hsieh, Hsin-Tzu Chang, Ying-Shan Chen, Tzu-Wei Lin, Han-Sui Hsu, Cheng-Wen Wu
Journal: Cancer Research
Cancer Res (2010) 70 (24): 10433–10444.
https://doi.org/10.1158/0008-5472.CAN-10-2638
Published: 14 December 2010
View articletitled, Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation
Open the PDF for Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation in another window
Includes: Supplementary data
Journal Articles

Gene profiling of genistein’s effect in men with prostate cancer.

Yongzeng Ding, Li Xu, Shan Chen, William Catalona, David L. Kelly, Borko Jovanovic, Irene B. Helenowski, Ximing Yang, Michael Pins, Raymond Bergan
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1234–1235.
Published: 15 April 2006
View articletitled, Gene profiling of genistein’s effect in men with prostate cancer.
Journal Articles

Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells

Xiaoke Huang, Shan Chen, Li Xu, Yueqin Liu, Dilip K. Deb, Leonidas C. Platanias, Raymond C. Bergan
Journal: Cancer Research
Cancer Res (2005) 65 (8): 3470–3478.
https://doi.org/10.1158/0008-5472.CAN-04-2807
Published: 15 April 2005
View articletitled, Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells
Open the PDF for Genistein Inhibits p38 Map Kinase Activation, Matrix Metalloproteinase Type 2, and Cell Invasion in Human Prostate Epithelial Cells in another window
Journal Articles

Gene expression profiles of MCF-7aro after hormone/inhibitor-treatment

Toru Itoh, Yate-Ching Yuan, David Smith, Kimberly Karlsberg, Jing-Jing Ye, Ikuko Kijima, Fun Shan Chen, Shiuan Chen
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 106.
Published: 01 April 2004
View articletitled, Gene expression profiles of MCF-7aro after hormone/inhibitor-treatment
Journal Articles

Expression of Carcinoembryonic Antigen and Its Predicted Immunoglobulin-like Domains in HeLa Cells for Epitope Analysis

Laura J. F. Hefta, Fun-Shan Chen, Michael Ronk, Sybille L. Sauter, Virender Sarin, Shinzo Oikawa, Hiroshi Nakazato, Stanley Hefta, John E. Shively
Journal: Cancer Research
Cancer Res (1992) 52 (20): 5647–5655.
Published: 01 October 1992
View articletitled, Expression of Carcinoembryonic Antigen and Its Predicted Immunoglobulin-like Domains in HeLa Cells for Epitope Analysis
Open the PDF for Expression of Carcinoembryonic Antigen and Its Predicted Immunoglobulin-like Domains in HeLa Cells for Epitope Analysis in another window
Journal Articles

Cloning of the Genes for T84.66, an Antibody That Has a High Specificity and Affinity for Carcinoembryonic Antigen, and Expression of Chimeric Human/Mouse T84.66 Genes in Myeloma and Chinese Hamster Ovary Cells

Michael Neumaier, Louise Shively, Fun-Shan Chen, Franz-Josef Gaida, Christine Ilgen, Raymond J. Paxton, John E. Shively, Arthur D. Riggs
Journal: Cancer Research
Cancer Res (1990) 50 (7): 2128–2134.
Published: 01 April 1990
View articletitled, Cloning of the Genes for T84.66, an Antibody That Has a High Specificity and Affinity for Carcinoembryonic Antigen, and Expression of Chimeric Human/Mouse T84.66 Genes in Myeloma and Chinese Hamster Ovary Cells
Open the PDF for Cloning of the Genes for T84.66, an Antibody That Has a High Specificity and Affinity for Carcinoembryonic Antigen, and Expression of Chimeric Human/Mouse T84.66 Genes in Myeloma and Chinese Hamster Ovary Cells in another window
Journal Articles

Effects of Vincristine on Cell Survival, Cell Cycle Progression, and Mitotic Accumulation in Asynchronously Growing Sarcoma 180 Cells

Hamza Mujagic, Shan-Shan Chen, Richard Geist, Sandra J. Occhipinti, Bruce M. Conger, Charles A. Smith, William H. Schuette, Stanley E. Shackney
Journal: Cancer Research
Cancer Res (1983) 43 (8): 3591–3597.
Published: 01 August 1983
View articletitled, Effects of Vincristine on Cell Survival, Cell Cycle Progression, and Mitotic Accumulation in Asynchronously Growing Sarcoma 180 Cells
Open the PDF for Effects of Vincristine on Cell Survival, Cell Cycle Progression, and Mitotic Accumulation in Asynchronously Growing Sarcoma 180 Cells in another window