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Seth A. Ettenberg
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Journal Articles

Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110α Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers

Joan T. Garrett, Cammie R. Sutton, Richard Kurupi, Carl Uli Bialucha, Seth A. Ettenberg, Scott D. Collins, Qing Sheng, Jerry Wallweber, Lisa DeFazio-Eli, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2013) 73 (19): 6013–6023.
https://doi.org/10.1158/0008-5472.CAN-13-1191
Published: 01 October 2013
View article titled, Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110α Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers
Open the PDF for Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110α Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers in another window
Includes: Supplementary data
Journal Articles

An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin

Andrew P. Garner, Carl U. Bialucha, Elizabeth R. Sprague, Joan T. Garrett, Qing Sheng, Sharon Li, Olga Sineshchekova, Parmita Saxena, Cammie R. Sutton, Dongshu Chen, Yan Chen, Huiqin Wang, Jinsheng Liang, Rita Das, Rebecca Mosher, Jian Gu, Alan Huang, Nicole Haubst, Carolin Zehetmeier, Manuela Haberl, Winfried Elis, Christian Kunz, Analeah B. Heidt, Kara Herlihy, Joshua Murtie, Alwin Schuller, Carlos L. Arteaga, William R. Sellers, Seth A. Ettenberg
Journal: Cancer Research
Cancer Res (2013) 73 (19): 6024–6035.
https://doi.org/10.1158/0008-5472.CAN-13-1198
Published: 01 October 2013
View article titled, An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Open the PDF for An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin in another window
Includes: Supplementary data
Journal Articles

Abstract 5461: A HER3 antibody that blocks ligand-independent HER2-HER3 dimerization sensitizes to HER2 and PI3K inhibitors .

Joan T. Garrett, Cammie R. Sutton, Carl Uli Bialucha, Seth A. Ettenberg, Jerry Wallweber, Lisa DeFazio-Eli, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5461.
https://doi.org/10.1158/1538-7445.AM2013-5461
Published: 15 April 2013
View article titled, Abstract 5461: A HER3 antibody that blocks ligand-independent HER2-HER3 dimerization sensitizes to HER2 and PI3K inhibitors .
Journal Articles

Abstract 3794: Inhibition of prostate cancer bone metastases by the dickkopf-1 neutralizing antibody BHQ880

Joseph L. Sottnik, Christopher Hall, Andreas Karatsinides, Andrew L. Keller, Seth A. Ettenberg, Evan T. Keller
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3794.
https://doi.org/10.1158/1538-7445.AM2012-3794
Published: 15 April 2012
View article titled, Abstract 3794: Inhibition of prostate cancer bone metastases by the dickkopf-1 neutralizing antibody BHQ880
Journal Articles

CR064, a fully human monoclonal antibody to angiopoietin related protein 4 (ARP4) inhibits ARP4-mediated angiogenesis and renal cell carcinoma survival in vitro

Haihong Zhong, Seth A. Ettenberg, Mohan Dhanabal, Melanie Baron, Nikolai Khramtsov, Ferenc Boldog, Qing Zhou, Henri Lichenstein, Gulshan Ara, William J. Larochelle
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 706.
Published: 01 May 2005
View article titled, CR064, a fully human monoclonal antibody to angiopoietin related protein 4 (ARP4) inhibits ARP4-mediated angiogenesis and renal cell carcinoma survival in vitro
Journal Articles

Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b

Gareth C. Davies, Seth A. Ettenberg, Ashley O. Coats, Mark Mussante, Sarangan Ravichandran, Jack Collins, Marion M. Nau, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 907.
Published: 01 April 2004
View article titled, Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b
Journal Articles

Down-Regulation of the erbB-2 Receptor by Trastuzumab (Herceptin) Enhances Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Breast and Ovarian Cancer Cell Lines that Overexpress erbB-2

Mauricio Cuello, Seth A. Ettenberg, Amy S. Clark, Maccon M. Keane, Reuben H. Posner, Marion M. Nau, Phillip A. Dennis, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (2001) 61 (12): 4892–4900.
Published: 01 June 2001
View article titled, Down-Regulation of the erbB-2 Receptor by Trastuzumab (Herceptin) Enhances Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Breast and Ovarian Cancer Cell Lines that Overexpress erbB-2
Open the PDF for Down-Regulation of the erbB-2 Receptor by Trastuzumab (Herceptin) Enhances Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Breast and Ovarian Cancer Cell Lines that Overexpress erbB-2 in another window
Journal Articles

Chemotherapy Augments TRAIL-induced Apoptosis in Breast Cell Lines

Maccon M. Keane, Seth A. Ettenberg, Marion M. Nau, Edward K. Russell, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (1999) 59 (3): 734–741.
Published: 01 February 1999
View article titled, Chemotherapy Augments TRAIL-induced Apoptosis in Breast Cell Lines
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Journal Articles

Fas Expression and Function in Normal and Malignant Breast Cell Lines

Maccon M. Keane, Seth A. Ettenberg, Geoffrey A. Lowrey, Edward K. Russell, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (1996) 56 (20): 4791–4798.
Published: 01 October 1996
View article titled, Fas Expression and Function in Normal and Malignant Breast Cell Lines
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Journal Articles

The Protein Tyrosine Phosphatase DEP-1 Is Induced during Differentiation and Inhibits Growth of Breast Cancer Cells

Maccon M. Keane, Geoffrey A. Lowrey, Seth A. Ettenberg, Mark A. Dayton, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (1996) 56 (18): 4236–4243.
Published: 01 September 1996
View article titled, The Protein Tyrosine Phosphatase DEP-1 Is Induced during Differentiation and Inhibits Growth of Breast Cancer Cells
Open the PDF for The Protein Tyrosine Phosphatase DEP-1 Is Induced during Differentiation and Inhibits Growth of Breast Cancer Cells in another window