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Journal Articles

Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization

Ken Kumagai, Takahiro Shimizu, Atsushi Takai, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Tomonori Hirano, Haruhiko Takeda, Aya Mizuguchi, Mari Teramura, Takahiko Ito, Eriko Iguchi, Mitsuhiro Nikaido, Yuji Eso, Ken Takahashi, Yoshihide Ueda, Shin'ichi Miyamoto, Kazutaka Obama, Seishi Ogawa, Hiroyuki Marusawa, Hiroshi Seno
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1712–1723.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-1523
Published: 03 May 2022
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Includes: Supplementary data
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The Evolving Genomic Landscape of Esophageal Squamous Cell Carcinoma Under Chemoradiotherapy

Hidenari Hirata, Atsushi Niida, Nobuyuki Kakiuchi, Ryutaro Uchi, Keishi Sugimachi, Takaaki Masuda, Tomoko Saito, Shun-Ichiro Kageyama, Yushi Motomura, Shuhei Ito, Tadamasa Yoshitake, Daisuke Tsurumaru, Yusuke Nishimuta, Akira Yokoyama, Takanori Hasegawa, Kenichi Chiba, Yuichi Shiraishi, Junyan Du, Fumihito Miura, Masaru Morita, Yasushi Toh, Masakazu Hirakawa, Yoshiyuki Shioyama, Takashi Ito, Tetsuo Akimoto, Satoru Miyano, Tatsuhiro Shibata, Masaki Mori, Yutaka Suzuki, Seishi Ogawa, Kousei Ishigami, Koshi Mimori
Journal: Cancer Research
Cancer Res (2021) 81 (19): 4926–4938.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0653
Published: 01 October 2021
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Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Kosuke Aoki, Hiromichi Suzuki, Takashi Yamamoto, Kimiyo N. Yamamoto, Sachi Maeda, Yusuke Okuno, Melissa Ranjit, Kazuya Motomura, Fumiharu Ohka, Kuniaki Tanahashi, Masaki Hirano, Tomohide Nishikawa, Hiroyuki Shimizu, Yotaro Kitano, Junya Yamaguchi, Shintaro Yamazaki, Hideo Nakamura, Masamichi Takahashi, Yoshitaka Narita, Mitsutoshi Nakada, Shoichi Deguchi, Masahiro Mizoguchi, Yasutomo Momii, Yoshihiro Muragaki, Tatsuya Abe, Jiro Akimoto, Toshihiko Wakabayashi, Ryuta Saito, Seishi Ogawa, Hiroshi Haeno, Atsushi Natsume
Journal: Cancer Research
Cancer Res (2021) 81 (18): 4861–4873.
DOI: https://doi.org/10.1158/0008-5472.CAN-21-0985
Published: 15 September 2021
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Includes: Supplementary data
Journal Articles

Abstract 3132: Tumorigenesis of MEN2 pheochromocytoma

Tatsuki Ogasawara, Yoichi Fujii, Nobuyuki Kakiuchi, Yusuke Shiozawa, Hiromichi Suzuki, Ryuichi Sakamoto, Yusaku Yoshida, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3132.
DOI: https://doi.org/10.1158/1538-7445.AM2021-3132
Published: 01 July 2021
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Journal Articles

Abstract 2276: Genetic classification of colorectal cancer

Yoshikage Inoue, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhito Nanya, Yusuke Shiozawa, Yasuhide Takeuchi, Yoichi Fujii, Yuichi Shiraishi, Kenichi Chiba, Tetsuichi Yoshizato, Satoshi Nagayama, Yoshiharu Sakai, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2276.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2276
Published: 01 July 2021
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Journal Articles

Abstract 92: Clonal evolution of proliferative lesions into breast cancers

Tomomi Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Hirona Maeda, Yusuke Shiozawa, Masahiro M. Nakagawa, Yotaro Ochi, Yukiko Kawata, Kosuke Aoki, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Satoko Baba, Yuichi Shiraishi, Kenichi Chiba, Kengo Takeuchi, Hironori Haga, Satoru Miyano, Masakazu Toi, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 92.
DOI: https://doi.org/10.1158/1538-7445.AM2021-92
Published: 01 July 2021
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Journal Articles

Abstract 2675: Clonal expansion of skin keratinocyte

Yoshihiro Ishida, Nobuyuki Kakiuchi, Yoichi Fujii, Tomonori Hirano, Yoshikage Inoue, Tomomi Nishimura, Tatsuki Ogasawara, Hirona Maeda, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Atsushi Otsuka, Kenji Kabashima, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2675.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2675
Published: 01 July 2021
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Abstract 2185: Genetic analysis of metachronous pancreatic cancers

Tomonori Hirano, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Tomomi Nishimura, Toshihiko Masui, Sachiko Minamiguhi, Hironori Haga, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Uza Norimitsu, Yuzo Kodama, Hiroshi Seno, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2185.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2185
Published: 01 July 2021
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Journal Articles

Abstract 3547: Frequent genomic alterations to evade the immune system in colorectal cancer with POLE gene mutation

Yoshikage Inoue, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Tetsuichi Yoshizato, Hiroko Tanaka, Ai Okada, Satoshi Nagayama, Satoru Miyano, Yoshiharu Sakai, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3547.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3547
Published: 15 August 2020
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Abstract 1309: Distinct molecular subtypes and a high diagnostic urinary biomarker of upper urinary tract urothelial carcinoma

Yoichi Fujii, Yusuke Sato, Hiromichi Suzuki, Tetsuichi Yoshizato, Kenichi Yoshida, Yuichi Shiraishi, Taketo Kawai, Tohru Nakagawa, Hiroaki Nishimatsu, Toshikazu Nishimatsu, Masashi Sanada, Hideki Makishima, Satoru Miyano, Haruki Kume, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1309.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1309
Published: 15 August 2020
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Journal Articles

Abstract 5875: Analysis of clonal expansion in epithelium affected by ulcerative colitis reveals frequent mutations affecting IL-17 signaling pathway and novel cancer vulnerability

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Akaki Kotaro, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Tomonori Hirano, Yasuhide Takeuchi, Hiroyuki Miyoshi, Yoshiharu Sakai, Hironori Haga, Seiichi Hirota, Hiroki Ikeuchi, Osamu Takeuchi, Satoru Miyano, Hiroshi Seno, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5875.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5875
Published: 15 August 2020
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Journal Articles

Abstract 5877: Genetic analysis of metachronous pancreatic cancers

Hirano Tomonori, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Yoshikage Inoue, Tomomi Nishimura, Yoichi Fujii, Akira Yokoyama, Hideki Makishima, Toshihiko Masui, Shinji Uemoto, Sachiko Minamiguchi, Hironori Haga, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Satoru Miyano, Norimitsu Uza, Yuzo Kodama, Hiroshi Seno, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5877.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5877
Published: 15 August 2020
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Journal Articles

Abstract 225: Frequent abnormalities in TP53 and increased genetic instability in myxofibrosarcoma

Yasuhide Takeuchi, Annegret Kunitz, Adriane Halik, Hiromichi Suzuki, Kenichi Yoshida, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Nobuyuki Kakiuchi, Yusuke Shiozawa, Akira Yokoyama, Yoshikage Inoue, Tetsuichi Yoshizato, Kosuke Aoki, Yoichi Fujii, Yasuhito Nannya, Hideki Makishima, Satoru Miyano, Hironori Haga, Frederik Damm, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 225.
DOI: https://doi.org/10.1158/1538-7445.AM2020-225
Published: 15 August 2020
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Journal Articles

Abstract 4902: Clonal evolution of proliferative lesions into breast cancers

Tomomi Nishimura, Nobuyuki Kakiuchi, Kenichi Yoshida, Yasuhide Takeuchi, Hirona Maeda, Yusuke Shiozawa, Masahiro M. Nakagawa, Yotaro Ochi, Yukiko Kawata, Kosuke Aoki, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Satoko Baba, Yuichi Shiraishi, Kenichi Chiba, Kengo Takeuchi, Hironori Haga, Satoru Miyano, Masakazu Toi, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4902.
DOI: https://doi.org/10.1158/1538-7445.AM2020-4902
Published: 15 August 2020
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Journal Articles

Dasatinib Is an Effective Treatment for Angioimmunoblastic T-cell Lymphoma

Tran B. Nguyen, Mamiko Sakata-Yanagimoto, Manabu Fujisawa, Sharna Tanzima Nuhat, Hiroaki Miyoshi, Yasuhito Nannya, Koichi Hashimoto, Kota Fukumoto, Olivier A. Bernard, Yusuke Kiyoki, Kantaro Ishitsuka, Haruka Momose, Shinichiro Sukegawa, Atsushi Shinagawa, Takuya Suyama, Yuji Sato, Hidekazu Nishikii, Naoshi Obara, Manabu Kusakabe, Shintaro Yanagimoto, Seishi Ogawa, Koichi Ohshima, Shigeru Chiba
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (9): 1875–1884.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-2787
Published: 04 May 2020
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Abstract P2-10-12: Relationship between predicted risks of carrying breast cancer susceptibility genes and the presence of germline variants in Japanese patients with primary breast cancer

Noriko Senda, Nobuko Kawaguchi-Sakita, Masahiro Kawashima, Yukiko Inagaki-Kawata, Kenichi Yoshida, Tomomi Nishimura, Masahiro Takada, Eiji Suzuki, Yuki Kataoka, Fumiaki Sato, Yoshiaki Matsumoto, Masae Torii, Hiroshi Yoshibayashi, Kazuhiro Yamagami, Shigeru Tsuyuki, Akira Yamauchi, Nobuhiko Shinkura, Hironori Kato, Yoshio Moriguchi, Ryuji Okamura, Norimichi Kan, Hirofumi Suwa, Shingo Sakata, Susumu Mashima, Fumiaki Yotsumoto, Tsuyoshi Tachibana, Mitsuru Tanaka, Takashi Inamoto, Masahiro Sugimoto, Seishi Ogawa, Masakazu Toi
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-10-12.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-10-12
Published: 15 February 2020
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Journal Articles

Abstract P1-10-15: BRCA1 alterations with additional defects in DNA damage repair genes may confer chemoresistance to BRCA-like breast cancers treated with neoadjuvant chemotherapy

Mamoru Takada, Yasuhiko Kaneko, Masayuki Haruta, Shigenori Nagai, Kenichi Inoue, Katsunori Toduka, Masafumi Kurozumi, Hiroyuki Takei, Seishi Ogawa, Takeshi Nagashima, Takafumi Sangai, Hiroshi Fujimoto, Junta Sakakibara, Ryotaro Teranaka
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P1-10-15.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P1-10-15
Published: 15 February 2020
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Abstract P4-05-15: Clonal evolution of proliferative lesions into breast cancers

Tomomi Nishimura, Kenichi Yoshida, Nobuyuki Kakiuchi, Yasuhide Takeuchi, Yukiko Kawata, Hirona Maeda, Yusuke Shiozawa, Kosuke Aoki, Masahiro Hirata, Tatsuki R Kataoka, Takaki Sakurai, Satoko Baba, Yuichi Shiraishi, Kenichi Chiba, Kengo Takeuchi, Hironori Haga, Satoru Miyano, Masakazu Toi, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-05-15.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P4-05-15
Published: 15 February 2020
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Abstract 1683: Mutational landscape of colorectal cancer with POLE gene mutation

Yoshikage Inoue, Nobuyuki Kakiuchi, Kenichi Yoshida, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Tetsuichi Yoshizato, HIroko Tanaka, Satoshi Nagayama, Satoru Miyano, Yoshiharu Sakai, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1683.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1683
Published: 01 July 2019
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Abstract 3403: Genetic analysis of pheochromocytoma

Tatsuki Ogasawara, Yoichi Fujii, Masanori Fujimoto, Yusuke Shiozawa, Tetsuichi Yoshizato, Hiromichi Suzuki, Kenichi Yoshida, Yuichi Shiraishi, Hideki Makishima, Satoru Miyano, Tomoaki Tanaka, Seishi Ogawa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3403.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3403
Published: 01 July 2019
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