Page 1 | Search Results | Cancer Research | American Association for Cancer Research

1-20 of 33

Sort by

Sort Order Select

Journal Articles

Abstract LB339: PARP inhibition reprograms CD8 T cells, enhancing their function and generation of prolonged memory, leading to greater anti-tumor immune response

Wael Traboulsi, Subhadip Kundu, Pankaj Gaur, Zainab Ramlaoui, Dareen Sarhan, Nour Shobaki, Jacob Lee, Nazli Jafarzadeh, Simon T. Barry, Viia E. Valge-Archer, Vivek Verma, Seema Gupta, Samir N. Khleif

Cancer Res (2023) 83 (8_Supplement): LB339.

https://doi.org/10.1158/1538-7445.AM2023-LB339

Published: 14 April 2023

View article titled, Abstract LB339: PARP inhibition reprograms CD8 T cells, enhancing their function and generation of prolonged memory, leading to greater anti-tumor immune response

Journal Articles

Abstract 4217: MEKi in combination with anti-OX40 generates metabolically fit effector CD8⁺ T cells, enhances stem cell-like memory CD8⁺ T cells, and leads to strong anti-tumor activity

Pankaj Gaur, Vivek Verma, Mays Alreem Elayyan, Zainab Ramlaoui, Simon T. Barry, Viia E. Valge-Archer, Paul D. Smith, Seema Gupta, Samir N. Khleif

Cancer Res (2022) 82 (12_Supplement): 4217.

https://doi.org/10.1158/1538-7445.AM2022-4217

Published: 15 June 2022

View article titled, Abstract 4217: MEKi in combination with anti-OX40 generates metabolically fit effector CD8+ T cells, enhances stem cell-like memory CD8+ T cells, and leads to strong anti-tumor activity

Journal Articles

Abstract LB566: Class 1 HDAC inhibition induces antitumor immunity by NF-kB-mediated enhanced metabolic fitness and generation of unique effector function enriched memory CD8 T cell subtype

Nour Shobaki, Pankaj Gaur, Rahul Nadre, Vivek Verma, Peter Ordentlich, Lei Wang, Nazli Jafarzadeh, Wael Traboulsi, Mikayel Mkrtichyan, Seema Gupta, Samir N. Khleif

Cancer Res (2022) 82 (12_Supplement): LB566.

https://doi.org/10.1158/1538-7445.AM2022-LB566

Published: 15 June 2022

View article titled, Abstract LB566: Class 1 HDAC inhibition induces antitumor immunity by NF-kB-mediated enhanced metabolic fitness and generation of unique effector function enriched memory CD8 T cell subtype

Journal Articles

Abstract LB217: Ascorbic acid rescues antitumor immune response by reversing hypoxia-induced CD8⁺T cell dysfunction

Nazli Jafarzadeh, Pankaj Gaur, Dareen Sarhan, Nour Shobaki, Wael Traboulsi, Zainab Ramlaoui, Vivek Verma, Seema Gupta, Samir N. Khleif

Cancer Res (2022) 82 (12_Supplement): LB217.

https://doi.org/10.1158/1538-7445.AM2022-LB217

Published: 15 June 2022

View article titled, Abstract LB217: Ascorbic acid rescues antitumor immune response by reversing hypoxia-induced CD8+T cell dysfunction

Journal Articles

Abstract 2881: Proper priming of T cells is crucial for the anti-tumor effect of mPTX-35, an anti-TNFRSF25 agonist antibody

Dareen Sarhan, Lara Rabah, Vikas Tahiliani, Anh M. Trinh, Rahul R. Jasuja, Eric P. Dixon, Matthew Seavey, Vivek Verma, Seema Gupta, Samir N. Khleif

Cancer Res (2022) 82 (12_Supplement): 2881.

https://doi.org/10.1158/1538-7445.AM2022-2881

Published: 15 June 2022

View article titled, Abstract 2881: Proper priming of T cells is crucial for the anti-tumor effect of mPTX-35, an anti-TNFRSF25 agonist antibody

Journal Articles

Abstract LB018: Cloud-based biological domain knowledge derived gene expression classifier to predict the cancer clinical outcome

Rao V. Papineni, Seema Gupta, Aravindan Natarajan, Ram Papineni, Chandra Kasinathan

Cancer Res (2021) 81 (13_Supplement): LB018.

https://doi.org/10.1158/1538-7445.AM2021-LB018

Published: 01 July 2021

View article titled, Abstract LB018: Cloud-based biological domain knowledge derived gene expression classifier to predict the cancer clinical outcome

Journal Articles

Abstract 2920: Lymphoblast cells secrete putative protein factors in response to high-dose radiation causing anti-tumor effect in lung cancer cells

Kamila Rawojc, Anthony Yeung, Mansoor M. Ahmed, Seema Gupta

Cancer Res (2019) 79 (13_Supplement): 2920.

https://doi.org/10.1158/1538-7445.AM2019-2920

Published: 01 July 2019

View article titled, Abstract 2920: Lymphoblast cells secrete putative protein factors in response to high-dose radiation causing anti-tumor effect in lung cancer cells

Journal Articles

Abstract 3761: Histone deacetylase inhibitor, Entinostat enhances the tumor specific immune response by generating T-cell central memory in the TME

Pankaj Gaur, Vivek Verma, Rahul Nandre, Pooja Vir, Hua Wang, Baolin Kang, Peter Ordentlich, Lei Wang, Seema Gupta, Samir N. Khleif

Cancer Res (2018) 78 (13_Supplement): 3761.

https://doi.org/10.1158/1538-7445.AM2018-3761

Published: 01 July 2018

View article titled, Abstract 3761: Histone deacetylase inhibitor, Entinostat enhances the tumor specific immune response by generating T-cell central memory in the TME

Journal Articles

Abstract 3773: RORγ agonist enhances antitumor effects of agonist anti-OX40 antibody

Pankaj Gaur, Vivek Verma, Rahul Nandre, Pooja Vir, Hua Wang, Baolin Kang, Laura Carter, Xiao Hu, Xikui Liu, Seema Gupta, Samir Khleif

Cancer Res (2018) 78 (13_Supplement): 3773.

https://doi.org/10.1158/1538-7445.AM2018-3773

Published: 01 July 2018

View article titled, Abstract 3773: RORγ agonist enhances antitumor effects of agonist anti-OX40 antibody

Journal Articles

Abstract 3763: IDO vaccine enhances antigen-specific anti-tumor effects by reducing IDO-expressing antigen presenting cells and MDSCs

Rahul Nandre, Vivek Verma, Pankaj Gaur, Pooja Vir, Hua Wang, Baolin Kang, Ayako Wakatsuki Pedersen, Mai-Britt Zocca, Mads Hald Andersen, Seema Gupta, Samir Khleif

Cancer Res (2018) 78 (13_Supplement): 3763.

https://doi.org/10.1158/1538-7445.AM2018-3763

Published: 01 July 2018

View article titled, Abstract 3763: IDO vaccine enhances antigen-specific anti-tumor effects by reducing IDO-expressing antigen presenting cells and MDSCs

Journal Articles

Abstract 3762: Novel RORγt agonist induces antitumor immune effect through enhancement of tumor antigen-specific CD8⁺ T-cell infiltration into the TME

Pankaj Gaur, Vivek Verma, Rahul Nandre, Pooja Vir, Hua Wang, Baolin Kang, Laura Carter, Xiao Hu, Xikui Liu, Seema Gupta, Samir Khleif

Cancer Res (2018) 78 (13_Supplement): 3762.

https://doi.org/10.1158/1538-7445.AM2018-3762

Published: 01 July 2018

View article titled, Abstract 3762: Novel RORγt agonist induces antitumor immune effect through enhancement of tumor antigen-specific CD8+ T-cell infiltration into the TME

Journal Articles

Abstract 3777: RORγ agonist enhances antitumor effects of immune checkpoint anti-PD1

Pankaj Gaur, Vivek Verma, Rahul Nandre, Pooja Vir, Hua Wang, Baolin Kang, Laura Carter, Xiao Hu, Xikui Liu, Seema Gupta, Samir Khleif

Cancer Res (2018) 78 (13_Supplement): 3777.

https://doi.org/10.1158/1538-7445.AM2018-3777

Published: 01 July 2018

View article titled, Abstract 3777: RORγ agonist enhances antitumor effects of immune checkpoint anti-PD1

Journal Articles

Abstract 4717: MAP kinase inhibition induces metabolic reprogramming in T-cells leading to induction of stem cell memory CD8 cells that enhance potency of adoptive cell therapy and anti-OX40 antibody

Vivek Verma, Shamim Ahmad, Peng Zeng, Mikayel Mkrtichyan, Simon T. Barry, Paul D. Smith, Paulo C. Rodriguez, John E. Janik, Seema Gupta, Samir N. Khleif

Cancer Res (2018) 78 (13_Supplement): 4717.

https://doi.org/10.1158/1538-7445.AM2018-4717

Published: 01 July 2018

View article titled, Abstract 4717: MAP kinase inhibition induces metabolic reprogramming in T-cells leading to induction of stem cell memory CD8 cells that enhance potency of adoptive cell therapy and anti-OX40 antibody

Journal Articles

Abstract LB-359: Effects of space time fractionated radiation on normal tissue toxicity

Xiaodong Wu, Seema Gupta, Saleem Umar, Alok K. Agarwal, Alan Pollack, Mansoor M. Ahmed

Cancer Res (2011) 71 (8_Supplement): LB-359.

https://doi.org/10.1158/1538-7445.AM2011-LB-359

Published: 15 April 2011

View article titled, Abstract LB-359: Effects of space time fractionated radiation on normal tissue toxicity

Journal Articles

Abstract LB-370: Radiation and hypoxia-induced bystander effect in human lung cancer cells

Slavisa Tubin, Seema Gupta, Mansoor M. Ahmed

Cancer Res (2011) 71 (8_Supplement): LB-370.

https://doi.org/10.1158/1538-7445.AM2011-LB-370

Published: 15 April 2011

View article titled, Abstract LB-370: Radiation and hypoxia-induced bystander effect in human lung cancer cells

Journal Articles

Abstract LB-376: Prediction of clinical outcome using NFkB target gene expression based classifier in head and neck patients with different HPV status

Seema Gupta, Tulay Koru-Sengul, Sakhi Philip, Robert Brown, Phillip Pellitteri, Jarrad W. Goodwin, Mansoor M. Ahmed

Cancer Res (2011) 71 (8_Supplement): LB-376.

https://doi.org/10.1158/1538-7445.AM2011-LB-376

Published: 15 April 2011

View article titled, Abstract LB-376: Prediction of clinical outcome using NFkB target gene expression based classifier in head and neck patients with different HPV status

Journal Articles

Abstract 5542: Activation of epidermal growth factor receptor potentiates effects of radiation in A549 lung cancer cells

Seema Gupta, Chandra Childress, Mansoor M. Ahmed, Wannian Yang

Cancer Res (2010) 70 (8_Supplement): 5542.

https://doi.org/10.1158/1538-7445.AM10-5542

Published: 15 April 2010

View article titled, Abstract 5542: Activation of epidermal growth factor receptor potentiates effects of radiation in A549 lung cancer cells

Journal Articles

Abstract #2987: Therapeutic effects of curcumin and thymoquinone in benign prostatic hyperplasia (BPH): Role of inflammatory cytokines and chemokines

Seema Gupta, Alyssa Park, Mohammed Shareef, Myra Wilkerson, Daniel Rukstalis, Mansoor Ahmed

Cancer Res (2009) 69 (9_Supplement): 2987.

Published: 01 May 2009

View article titled, Abstract #2987: Therapeutic effects of curcumin and thymoquinone in benign prostatic hyperplasia (BPH): Role of inflammatory cytokines and chemokines

Journal Articles

Chemosensitizing effects of high dose radiation-induced bystander factors in lung cancer

Seema Gupta, Jithender Gundawar, Mohammed Shareef, Richa Bhardawaj, J. S. Adhikari, B Dwarakanath, Mohammed Mohiuddin, Mansoor Ahmed

Cancer Res (2008) 68 (9_Supplement): 5761.

Published: 01 May 2008

View article titled, Chemosensitizing effects of high dose radiation-induced bystander factors in lung cancer

Journal Articles

Development of a cell line based gene classifier to predict therapeutic response of head and neck cancer patients

Seema Gupta, Sana Ghafoor, Craig Wood, Kathryn Masker, Robert Brown, Amy Law, Phillip Pellitteri, Ping Zhang, David Carey, Mansoor Ahmed

Cancer Res (2008) 68 (9_Supplement): 4098.

Published: 01 May 2008

View article titled, Development of a cell line based gene classifier to predict therapeutic response of head and neck cancer patients

NARROW

Abstract LB339: PARP inhibition reprograms CD8 T cells, enhancing their function and generation of prolonged memory, leading to greater anti-tumor immune response

Abstract 4217: MEKi in combination with anti-OX40 generates metabolically fit effector CD8⁺ T cells, enhances stem cell-like memory CD8⁺ T cells, and leads to strong anti-tumor activity

Abstract LB566: Class 1 HDAC inhibition induces antitumor immunity by NF-kB-mediated enhanced metabolic fitness and generation of unique effector function enriched memory CD8 T cell subtype

Abstract LB217: Ascorbic acid rescues antitumor immune response by reversing hypoxia-induced CD8⁺T cell dysfunction

Abstract 2881: Proper priming of T cells is crucial for the anti-tumor effect of mPTX-35, an anti-TNFRSF25 agonist antibody

Abstract LB018: Cloud-based biological domain knowledge derived gene expression classifier to predict the cancer clinical outcome

Abstract 2920: Lymphoblast cells secrete putative protein factors in response to high-dose radiation causing anti-tumor effect in lung cancer cells

Abstract 3761: Histone deacetylase inhibitor, Entinostat enhances the tumor specific immune response by generating T-cell central memory in the TME

Abstract 3773: RORγ agonist enhances antitumor effects of agonist anti-OX40 antibody

Abstract 3763: IDO vaccine enhances antigen-specific anti-tumor effects by reducing IDO-expressing antigen presenting cells and MDSCs

Abstract 3762: Novel RORγt agonist induces antitumor immune effect through enhancement of tumor antigen-specific CD8⁺ T-cell infiltration into the TME

Abstract 3777: RORγ agonist enhances antitumor effects of immune checkpoint anti-PD1

Abstract 4717: MAP kinase inhibition induces metabolic reprogramming in T-cells leading to induction of stem cell memory CD8 cells that enhance potency of adoptive cell therapy and anti-OX40 antibody

Abstract LB-359: Effects of space time fractionated radiation on normal tissue toxicity

Abstract LB-370: Radiation and hypoxia-induced bystander effect in human lung cancer cells

Abstract LB-376: Prediction of clinical outcome using NFkB target gene expression based classifier in head and neck patients with different HPV status

Abstract 5542: Activation of epidermal growth factor receptor potentiates effects of radiation in A549 lung cancer cells

Abstract #2987: Therapeutic effects of curcumin and thymoquinone in benign prostatic hyperplasia (BPH): Role of inflammatory cytokines and chemokines

Chemosensitizing effects of high dose radiation-induced bystander factors in lung cancer

Development of a cell line based gene classifier to predict therapeutic response of head and neck cancer patients

Email alerts

AACR Journals

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only