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Journal Articles

Abstract 250: Activating canonical p53 functions in tumor-associated macrophages improves immune checkpoint blockade efficacy

Cancer Res (2022) 82 (12_Supplement): 250.

DOI: https://doi.org/10.1158/1538-7445.AM2022-250

Published: 15 June 2022

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Journal Articles

Abstract PO-124: EZH2 blockade overcomes suppression of the proinflammatory senescence-associated secretory phenotype in the pancreas and drives NK cell-mediated pancreatic tumor responses

Loretah Chibaya, Yvette Lopez-Diaz, Haibo Liu, Katherine C. Murphy, John P. Morris, IV, Yu-jui Ho, Janelle Simon, Wei Luan, Amanda Kulick, Lakhena Leang, Elisa de Stanchina, Lihua J. Zhu, Scott W. Lowe, Marcus Ruscetti

Cancer Res (2021) 81 (22_Supplement): PO-124.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PO-124

Published: 15 November 2021

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Journal Articles

Abstract A29: Dissecting the mechanisms of senescence immune surveillance in liver cancer

Hsuan-An Chen, Direna Alonso-Curbelo, Yu-Jui Ho, John P. Morris, IV, Shauna Houlihan, Ryan Smolkin, Wei Luan, Ronald C. Hendrickson, Scott W. Lowe

Cancer Res (2020) 80 (11_Supplement): A29.

DOI: https://doi.org/10.1158/1538-7445.CAMODELS2020-A29

Published: 02 June 2020

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Journal Articles

Abstract PR01: Senescence induction triggers vascular remodeling and new vulnerabilities to chemo- and immunotherapy in pancreas cancer

Cancer Res (2019) 79 (24_Supplement): PR01.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-PR01

Published: 13 December 2019

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Journal Articles

Abstract I25: Understanding and exploiting natural barriers to pancreatic tumorigenesis

Scott W. Lowe

Cancer Res (2019) 79 (24_Supplement): I25.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-I25

Published: 13 December 2019

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Journal Articles

Abstract A59: CRISPR screen identifies global regulation of H3K36me2 as an epigenomic mechanism underlying epithelial plasticity in pancreatic ductal adenocarcinoma

Salina Yuan, Ramakrishnan Natesan, Francisco J. Sanchez-Rivera, Jinyang Li, Natarajan V Bhanu, Taiji Yamazoe, Jeffrey H. Lin, Allyson J. Merrell, Stacy K. Thomas, Junwei Shi, Ben A. Garcia, Scott W. Lowe, Irfan A. Asangani, Ben Z. Stanger

Cancer Res (2019) 79 (24_Supplement): A59.

DOI: https://doi.org/10.1158/1538-7445.PANCA19-A59

Published: 13 December 2019

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Journal Articles

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer

Gil Redelman-Sidi, Anna Binyamin, Isabella Gaeta, Wilhelm Palm, Craig B. Thompson, Paul B. Romesser, Scott W. Lowe, Mukta Bagul, John G. Doench, David E. Root, Michael S. Glickman

Cancer Res (2018) 78 (16): 4658–4670.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-3199

Published: 14 August 2018

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Includes: Supplementary data

Journal Articles

Abstract 4990: Regenerative origin of colorectal metastasis stem cells

Karuna Ganesh, Harihar Basnet, Kevin P. O'Rourke, Ashley M. Laughney, Lan He, Eduard Batlle, Scott W. Lowe, Dana Pe'er, Jinru Shia, Joan Massague

Cancer Res (2018) 78 (13_Supplement): 4990.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4990

Published: 01 July 2018

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Journal Articles

Abstract 5106: CRISPR/Cas9-based development of RNAi rat models for drug discovery

Prem K. Premsrirut, Chia-Lin Wang, Yu-Ting Yang, Lukas E. Dow, Johannes Zuber, Scott W. Lowe

Cancer Res (2018) 78 (13_Supplement): 5106.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5106

Published: 01 July 2018

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Journal Articles

Abstract IA21: Interrogating cancer drivers and dependencies using non-germline mouse models

Scott W. Lowe

Cancer Res (2018) 78 (10_Supplement): IA21.

DOI: https://doi.org/10.1158/1538-7445.MOUSEMODELS17-IA21

Published: 14 May 2018

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Journal Articles

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis

Daria G. Valerio, Haiming Xu, Chun-Wei Chen, Takayuki Hoshii, Meghan E. Eisold, Christopher Delaney, Monica Cusan, Aniruddha J. Deshpande, Chun-Hao Huang, Amaia Lujambio, YuJun George Zheng, Johannes Zuber, Tej K. Pandita, Scott W. Lowe, Scott A. Armstrong

Cancer Res (2017) 77 (7): 1753–1762.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-2374

Published: 02 April 2017

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Includes: Supplementary data

Journal Articles

Abstract 666: Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer

Kevin P. O’Rourke, Lukas E. Dow, Scott W. Lowe

Cancer Res (2016) 76 (14_Supplement): 666.

DOI: https://doi.org/10.1158/1538-7445.AM2016-666

Published: 15 July 2016

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Journal Articles

Abstract 2694: Histone acetyltransferase activity of MOF is required for MLL-AF9 leukemogenesis

Daria G. Valerio, Haiming Xu, Chun-Wei Chen, Takayuki Hoshii, Meghan Eisold, Christopher Delaney, Monica Cusan, Aniruddha J. Deshpande, Chun-Hao Huang, Amaia Lujambio, George Zheng, Tej K. Pandita, Scott W. Lowe, Scott A. Armstrong

Cancer Res (2016) 76 (14_Supplement): 2694.

DOI: https://doi.org/10.1158/1538-7445.AM2016-2694

Published: 15 July 2016

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Journal Articles

Abstract 2866: Defining epigenetic vulnerabilities in synovial sarcoma

Ana Banito, Nilgun Tasdemir, Marc Ladanyi, Scott W. Lowe

Cancer Res (2015) 75 (15_Supplement): 2866.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2866

Published: 01 August 2015

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Journal Articles

Abstract IA-5: Dissecting tumor suppressor gene networks in vivo

Scott W. Lowe

Cancer Res (2009) 69 (23_Supplement): IA-5.

DOI: https://doi.org/10.1158/0008-5472.FBCR09-IA-5

Published: 28 October 2014

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Journal Articles

Abstract A39: An oncogenomics-based in vivo cDNA screen pinpoints coamplified Ccnd1 and Fgf19 as therapeutic targets for liver cancer

Eric T. Sawey, Chunlin Cai, Amy Bakleh, Qing Liu, Scott W. Lowe, Scott Powers

Cancer Res (2009) 69 (23_Supplement): A39.

DOI: https://doi.org/10.1158/0008-5472.FBCR09-A39

Published: 28 October 2014

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Journal Articles

Abstract PR15: Inhibition of RNA Polymerase I as a therapeutic strategy for cancer-specific activation of p53

Cancer Res (2011) 71 (18_Supplement): PR15.

DOI: https://doi.org/10.1158/1538-7445.FBCR11-PR15

Published: 28 October 2014

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Journal Articles

Abstract 2974: RNAi mouse models: Revolutionizing drug discovery in vivo

Prem K. Premsrirut, BoYoung Yoon, Marina Pesic, Lukas E. Dow, Johannes Zuber, Scott W. Lowe, Gregory J. Hannon, Lars Zender, Christof Fellmann

Cancer Res (2014) 74 (19_Supplement): 2974.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2974

Published: 01 October 2014

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Journal Articles

Abstract 2935: RNAi screen identifies therapeutic targets in hepatocellular carcinoma

Chun-Hao Huang, Amaia Lujambio, Johannes Zuber, Thomas Kitzing, Darjus F. Tschaharganeh, Elisa D. Stanchina, Scott W. Lowe

Cancer Res (2014) 74 (19_Supplement): 2935.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2935

Published: 01 October 2014

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Journal Articles

Abstract LB-40: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition

Jessica Bolden, Nilgun Tasdemir, Lukas Dow, Johan H. van Es, John E. Wilkinson, Zhen Zhao, Hans Clevers, Scott W. Lowe

Cancer Res (2014) 74 (19_Supplement): LB-40.

DOI: https://doi.org/10.1158/1538-7445.AM2014-LB-40

Published: 01 October 2014

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NARROW

Abstract 250: Activating canonical p53 functions in tumor-associated macrophages improves immune checkpoint blockade efficacy

Abstract PO-124: EZH2 blockade overcomes suppression of the proinflammatory senescence-associated secretory phenotype in the pancreas and drives NK cell-mediated pancreatic tumor responses

Abstract A29: Dissecting the mechanisms of senescence immune surveillance in liver cancer

Abstract PR01: Senescence induction triggers vascular remodeling and new vulnerabilities to chemo- and immunotherapy in pancreas cancer

Abstract I25: Understanding and exploiting natural barriers to pancreatic tumorigenesis

Abstract A59: CRISPR screen identifies global regulation of H3K36me2 as an epigenomic mechanism underlying epithelial plasticity in pancreatic ductal adenocarcinoma

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer

Abstract 4990: Regenerative origin of colorectal metastasis stem cells

Abstract 5106: CRISPR/Cas9-based development of RNAi rat models for drug discovery

Abstract IA21: Interrogating cancer drivers and dependencies using non-germline mouse models

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis

Abstract 666: Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer

Abstract 2694: Histone acetyltransferase activity of MOF is required for MLL-AF9 leukemogenesis

Abstract 2866: Defining epigenetic vulnerabilities in synovial sarcoma

Abstract IA-5: Dissecting tumor suppressor gene networks in vivo

Abstract A39: An oncogenomics-based in vivo cDNA screen pinpoints coamplified Ccnd1 and Fgf19 as therapeutic targets for liver cancer

Abstract PR15: Inhibition of RNA Polymerase I as a therapeutic strategy for cancer-specific activation of p53

Abstract 2974: RNAi mouse models: Revolutionizing drug discovery in vivo

Abstract 2935: RNAi screen identifies therapeutic targets in hepatocellular carcinoma

Abstract LB-40: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition

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