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Scott M. Dehm
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Journal Articles

Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase

Chitra Rawat, Salma Ben-Salem, Nidhi Singh, Gaurav Chauhan, Anja Rabljenovic, Vishwa Vaghela, Varadha Balaji Venkadakrishnan, Jonathan D. Macdonald, Ujjwal R. Dahiya, Yara Ghanem, Salam Bachour, Yixue Su, Adam D. DePriest, Sanghee Lee, Michelle Muldong, Hyun-Tae Kim, Sangeeta Kumari, Malyn May Valenzuela, Dingxiao Zhang, Qiang Hu, Eduardo Cortes Gomez, Scott M. Dehm, Amina Zoubeidi, Christina A.M. Jamieson, Marlo Nicolas, Jesse McKenney, Belinda Willard, Eric A. Klein, Cristina Magi-Galluzzi, Shaun R. Stauffer, Song Liu, Hannelore V. Heemers
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4142–4160.
https://doi.org/10.1158/0008-5472.CAN-23-0883
Published: 15 December 2023
View article titled, Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
Open the PDF for Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase in another window
Includes: Supplementary data
Journal Articles

Abstract A022: Alternative polyadenylation as a therapeutic vulnerability in prostate cancer

Kiel T. Tietz, Braedan M. McClukey, Sarah A. Munro, Conor R. Miller, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A022.
https://doi.org/10.1158/1538-7445.PRCA2023-A022
Published: 02 June 2023
View article titled, Abstract A022: Alternative polyadenylation as a therapeutic vulnerability in prostate cancer
Journal Articles

Abstract A015: Citron kinase is a novel driver of prostate cancer progression and controls alternative splicing associated with treatment-resistance

Chitra Rawat, Nidhi Singh, Gaurav Chauhan, Anja Rabljenovic, Salma Ben-Salem, Vishwa Vaghela, Varadha B. Venkadakrishnan, Jonathan MacDonald, Ujjwal Dahiya, Adam D. DePriest, Sanghee Lee, Michelle Muldong, Hyun-Tae Kim, Sangeeta Kumari, Qiang Hu, Eduardo Cortes, Scott M. Dehm, Amina Zoubeidi, Christina A.M. Jamieson, Marlo Nicolas, Jesse McKenney, Belinda Willard, Eric A. Klein, Cristina Magi-Galluzzi, Shaun R. Stauffer, Song Liu, Hannelore V. Heemers
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): A015.
https://doi.org/10.1158/1538-7445.PRCA2023-A015
Published: 02 June 2023
View article titled, Abstract A015: Citron kinase is a novel driver of prostate cancer progression and controls alternative splicing associated with treatment-resistance
Journal Articles

Abstract B013: KLF5 drives basal cell identity to promote prostate cancer lineage plasticity

Samuel P. Pitzen, Yinjie Qiu, Sarah Munro, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B013.
https://doi.org/10.1158/1538-7445.PRCA2023-B013
Published: 02 June 2023
View article titled, Abstract B013: KLF5 drives basal cell identity to promote prostate cancer lineage plasticity
Journal Articles

Abstract IA003: Evolution of AR gene structure during prostate cancer progression

Scott M Dehm
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): IA003.
https://doi.org/10.1158/1538-7445.PRCA2023-IA003
Published: 02 June 2023
View article titled, Abstract IA003: Evolution of AR gene structure during prostate cancer progression
Journal Articles

Abstract LB048: AR-targeted linked-read sequencing reveals complex AR structural variants in CRPC tumors

Andrej Zivanovic, Sarah A. Munro, Jeffrey T. Miller, Yingming Li, Courtney N. Passow, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB048.
https://doi.org/10.1158/1538-7445.AM2023-LB048
Published: 14 April 2023
View article titled, Abstract LB048: AR-targeted linked-read sequencing reveals complex AR structural variants in CRPC tumors
Journal Articles

PEG10 Promoter–Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer

Mariya Shapovalova, John K. Lee, Yingming Li, Donald J. Vander Griend, Ilsa M. Coleman, Peter S. Nelson, Scott M. Dehm, Aaron M. LeBeau
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5668–5680.
https://doi.org/10.1158/0008-5472.CAN-19-2181
Published: 01 November 2019
View article titled, PEG10 Promoter–Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1813: The role of androgen receptor variant AR-V9 in prostate cancer

Yeung Ho, Jamie L. Van Etten, Christine Henzler, Yingming Li, Rendong Yang, Elizabeth Tseng, Ting Hon, Tyson Clark, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1813.
https://doi.org/10.1158/1538-7445.AM2018-1813
Published: 01 July 2018
View article titled, Abstract 1813: The role of androgen receptor variant AR-V9 in prostate cancer
Journal Articles

Abstract 3741: Deciphering the regulome of androgen receptor variants in prostate cancer

Mark L. Daniel, Theresa E. Hickey, Jason S. Carroll, Wayne D. Tilley, Luke A. Selth, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3741.
https://doi.org/10.1158/1538-7445.AM2018-3741
Published: 01 July 2018
View article titled, Abstract 3741: Deciphering the regulome of androgen receptor variants in prostate cancer
Journal Articles

Abstract 974: Alternative polyadenylation of androgen receptor variants in castration-resistant prostate cancer

Jamie L. Van Etten, Michael Nyquist, Yingming Li, Rebecca LaRue, Yeung Ho, Rendong Yang, Daniel F. Voytas, Christine Henzler, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 974.
https://doi.org/10.1158/1538-7445.AM2018-974
Published: 01 July 2018
View article titled, Abstract 974: Alternative polyadenylation of androgen receptor variants in castration-resistant prostate cancer
Journal Articles

Targeting a Single Alternative Polyadenylation Site Coordinately Blocks Expression of Androgen Receptor mRNA Splice Variants in Prostate Cancer

Jamie L. Van Etten, Michael Nyquist, Yingming Li, Rendong Yang, Yeung Ho, Rachel Johnson, Olivia Ondigi, Daniel F. Voytas, Christine Henzler, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5228–5235.
https://doi.org/10.1158/0008-5472.CAN-17-0320
Published: 01 October 2017
View article titled, Targeting a Single Alternative Polyadenylation Site Coordinately Blocks Expression of Androgen Receptor mRNA Splice Variants in Prostate Cancer
Open the PDF for Targeting a Single Alternative Polyadenylation Site Coordinately Blocks Expression of Androgen Receptor mRNA Splice Variants in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation

Yi Yin, Rui Li, Kangling Xu, Sentai Ding, Jeffrey Li, GuemHee Baek, Susmita G. Ramanand, Sam Ding, Zhao Liu, Yunpeng Gao, Mohammed S. Kanchwala, Xiangyi Li, Ryan Hutchinson, Xihui Liu, Solomon L. Woldu, Chao Xing, Neil B. Desai, Felix Y. Feng, Sandeep Burma, Johann S. de Bono, Scott M. Dehm, Ram S. Mani, Benjamin P.C. Chen, Ganesh V. Raj
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 4745–4754.
https://doi.org/10.1158/0008-5472.CAN-17-0164
Published: 14 September 2017
View article titled, Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation
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Includes: Supplementary data
Journal Articles

Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer

Steve Paltoglou, Rajdeep Das, Scott L. Townley, Theresa E. Hickey, Gerard A. Tarulli, Isabel Coutinho, Rayzel Fernandes, Adrienne R. Hanson, Iza Denis, Jason S. Carroll, Scott M. Dehm, Ganesh V. Raj, Stephen R. Plymate, Wayne D. Tilley, Luke A. Selth
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3417–3430.
https://doi.org/10.1158/0008-5472.CAN-16-1616
Published: 02 July 2017
View article titled, Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer
Open the PDF for Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 425: SMRT® Sequencing of full-length androgen receptor isoforms in prostate cancer reveals previously hidden drug resistant variants

Manish Kohli, Yeung Ho, David W. Hillman, Jamie L. Van Etten, Christine Henzler, Rendong Yang, Yingming Li, Elizabeth Tseng, Ting Hon, Tyson A. Clark, Liguo Wang, Kevin Silverstein, Liewei Wang, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 425.
https://doi.org/10.1158/1538-7445.AM2017-425
Published: 01 July 2017
View article titled, Abstract 425: SMRT® Sequencing of full-length androgen receptor isoforms in prostate cancer reveals previously hidden drug resistant variants
Journal Articles

mRNA Splicing Variants: Exploiting Modularity to Outwit Cancer Therapy

Scott M. Dehm
Journal: Cancer Research
Cancer Res (2013) 73 (17): 5309–5314.
https://doi.org/10.1158/0008-5472.CAN-13-0444
Published: 02 September 2013
View article titled, mRNA Splicing Variants: Exploiting Modularity to Outwit Cancer Therapy
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Journal Articles

Abstract IA18: Altered AR gene architecture and splicing in castration-resistant prostate cancer

Scott M. Dehm
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): IA18.
https://doi.org/10.1158/1538-7445.PRCA2012-IA18
Published: 09 May 2013
View article titled, Abstract IA18: Altered AR gene architecture and splicing in castration-resistant prostate cancer
Journal Articles

Abstract 1325: Chlorinated bisphenol A diglycidyl ether (EPI-001) mediates degradation of the androgen receptor in prostate cancer cells.

Lucas J. Brand, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1325.
https://doi.org/10.1158/1538-7445.AM2013-1325
Published: 15 April 2013
View article titled, Abstract 1325: Chlorinated bisphenol A diglycidyl ether (EPI-001) mediates degradation of the androgen receptor in prostate cancer cells.
Journal Articles

Abstract LB-136: Creation of androgen independent prostate cancer cell lines using targeting nucleases.

Michael D. Nyquist, Yingming Li, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-136.
https://doi.org/10.1158/1538-7445.AM2013-LB-136
Published: 15 April 2013
View article titled, Abstract LB-136: Creation of androgen independent prostate cancer cell lines using targeting nucleases.
Journal Articles

Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines

Yingming Li, Siu Chiu Chan, Lucas J. Brand, Tae Hyun Hwang, Kevin A.T. Silverstein, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2013) 73 (2): 483–489.
https://doi.org/10.1158/0008-5472.CAN-12-3630
Published: 16 January 2013
View article titled, Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
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Includes: Supplementary data
Journal Articles

Abstract 4556: AR intragenic rearrangement and altered androgen receptor mRNA splicing in castration-resistant prostate cancer

Yingming Li, Majid Alsagabi, Ahmed Tewfik, Scott M. Dehm
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4556.
https://doi.org/10.1158/1538-7445.AM2011-4556
Published: 15 April 2011
View article titled, Abstract 4556: AR intragenic rearrangement and altered androgen receptor mRNA splicing in castration-resistant prostate cancer