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Scott L. Friedman
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Journal Articles

Abstract 4718: Potent preclinical antitumor effects induced by pan-histone deacetylase inhibitor panobinostat in combination with sorafenib in hepatocellular carcinoma

Sara Toffanin, Anja Lachenmayer, Clara Alsinet, Laia Cabellos, Beatriz Minguez, Hung-Wen Tsai, Yujin Hoshida, Augusto Villanueva, Stephen C. Ward, Swan Thung, Scott L. Friedman, Josep M. Llovet
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4718.
https://doi.org/10.1158/1538-7445.AM2012-4718
Published: 15 April 2012
View article titled, Abstract 4718: Potent preclinical antitumor effects induced by pan-histone deacetylase inhibitor panobinostat in combination with sorafenib in hepatocellular carcinoma
Journal Articles

Abstract 2996: Overexpression of potential oncogenic microRNAs defines a new molecular subclass of hepatocellular carcinoma

Sara Toffanin, Yujin Hoshida, Anja Lachenmayer, Laia Cabellos, Jun Lu, Augusto Villanueva, Beatriz Minguez, Radoslav Savic, Derek Y. Chiang, Sasan Roayaie, Jordi Bruix, Myron E. Schwartz, Vincenzo Mazzaferro, Samuel Waxman, Scott L. Friedman, Todd R. Golub, Josep M. Llovet
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2996.
https://doi.org/10.1158/1538-7445.AM10-2996
Published: 15 April 2010
View article titled, Abstract 2996: Overexpression of potential oncogenic microRNAs defines a new molecular subclass of hepatocellular carcinoma
Journal Articles

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

Yujin Hoshida, Sebastian M.B. Nijman, Masahiro Kobayashi, Jennifer A. Chan, Jean-Philippe Brunet, Derek Y. Chiang, Augusto Villanueva, Philippa Newell, Kenji Ikeda, Masaji Hashimoto, Goro Watanabe, Stacey Gabriel, Scott L. Friedman, Hiromitsu Kumada, Josep M. Llovet, Todd R. Golub
Journal: Cancer Research
Cancer Res (2009) 69 (18): 7385–7392.
https://doi.org/10.1158/0008-5472.CAN-09-1089
Published: 14 September 2009
View article titled, Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

Derek Y. Chiang, Augusto Villanueva, Yujin Hoshida, Judit Peix, Philippa Newell, Beatriz Minguez, Amanda C. LeBlanc, Diana J. Donovan, Swan N. Thung, Manel Solé, Victoria Tovar, Clara Alsinet, Alex H. Ramos, Jordi Barretina, Sasan Roayaie, Myron Schwartz, Samuel Waxman, Jordi Bruix, Vincenzo Mazzaferro, Azra H. Ligon, Vesna Najfeld, Scott L. Friedman, William R. Sellers, Matthew Meyerson, Josep M. Llovet
Journal: Cancer Research
Cancer Res (2008) 68 (16): 6779–6788.
https://doi.org/10.1158/0008-5472.CAN-08-0742
Published: 12 August 2008
View article titled, Focal Gains of <em>VEGFA</em> and Molecular Classification of Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Downregulation of KLF6 is an early event in HCV related hepatocarcinogenesis

Sigal Kremer-Tal, Yingbei Chen, Goutham Narla, Eldad Hod, Myron Schwartz, Swan N. Thung, Maria I. Fiel, Vincenzo Mazzaferro, Jordi Bruix, Josep M. Llovet, Scott L. Friedman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 24–25.
Published: 15 April 2006
View article titled, Downregulation of KLF6 is an early event in HCV related hepatocarcinogenesis
Journal Articles

Dysregulation of hedgehog pathway signaling in hepatocellular carcinoma

Eric R. Lemmer, Yingbei Chen, Steven Yea, Elisa Wurmbach, Myron Schwartz, Gregory Khitrov, Augusto Villanueva, Goutham Narla, Samuel Waxman, Scott L. Friedman, Josep M. Llovet
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 630.
Published: 15 April 2006
View article titled, Dysregulation of hedgehog pathway signaling in hepatocellular carcinoma
Journal Articles

KLF6 and KLF6-SV1 regulate ovarian cancer progression and dissemination: Identification of a novel KLF6 / E-cadherin pathway

Analisa V. Difeo, Goutham Narla, Jennifer Hirshfeld, Olga Camacho-Vanegas, Jyothsna Narla, Hitomi Nishio, Stephen L. Rose, Shen Yao, Alice Levine, Tamara Kalir, Scott L. Friedman, Martin Walsh, Richard E. Buller, John A. Martignetti
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 977.
Published: 15 April 2006
View article titled, KLF6 and KLF6-SV1 regulate ovarian cancer progression and dissemination: Identification of a novel KLF6 / E-cadherin pathway
Journal Articles

Regulation of Krüppel-like Factor 6 Tumor Suppressor Activity by Acetylation

Dan Li, Steven Yea, Georgia Dolios, John A. Martignetti, Goutham Narla, Rong Wang, Martin J. Walsh, Scott L. Friedman
Journal: Cancer Research
Cancer Res (2005) 65 (20): 9216–9225.
https://doi.org/10.1158/0008-5472.CAN-05-1040
Published: 17 October 2005
View article titled, Regulation of Krüppel-like Factor 6 Tumor Suppressor Activity by Acetylation
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Journal Articles

Targeted Inhibition of the KLF6 Splice Variant, KLF6 SV1, Suppresses Prostate Cancer Cell Growth and Spread

Goutham Narla, Analisa DiFeo, Shen Yao, Asoka Banno, Eldad Hod, Helen L. Reeves, Rui F. Qiao, Olga Camacho-Vanegas, Alice Levine, Alexander Kirschenbaum, Andrew M. Chan, Scott L. Friedman, John A. Martignetti
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5761–5768.
https://doi.org/10.1158/0008-5472.CAN-05-0217
Published: 01 July 2005
View article titled, Targeted Inhibition of the KLF6 Splice Variant, KLF6 SV1, Suppresses Prostate Cancer Cell Growth and Spread
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Journal Articles

A Germline DNA Polymorphism Enhances Alternative Splicing of the KLF6 Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

Goutham Narla, Analisa DiFeo, Helen L. Reeves, Daniel J. Schaid, Jennifer Hirshfeld, Eldad Hod, Amanda Katz, William B. Isaacs, Scott Hebbring, Akira Komiya, Shannon K. McDonnell, Kathleen E. Wiley, Steven J. Jacobsen, Sarah D. Isaacs, Patrick C. Walsh, S. Lilly Zheng, Bao-Li Chang, Danielle M. Friedrichsen, Janet L. Stanford, Elaine A. Ostrander, Arul M. Chinnaiyan, Mark A. Rubin, Jianfeng Xu, Stephen N. Thibodeau, Scott L. Friedman, John A. Martignetti
Journal: Cancer Research
Cancer Res (2005) 65 (4): 1213–1222.
https://doi.org/10.1158/0008-5472.CAN-04-4249
Published: 25 February 2005
View article titled, A Germline DNA Polymorphism Enhances Alternative Splicing of the <em>KLF6</em> Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk
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Journal Articles

Cyclin-Dependent Kinase Inhibition by the KLF6 Tumor Suppressor Protein through Interaction with Cyclin D1

Sharon Benzeno, Goutham Narla, Jorge Allina, George Z. Cheng, Helen L. Reeves, Michaela S. Banck, Joseph A. Odin, J. Alan Diehl, Doris Germain, Scott L. Friedman
Journal: Cancer Research
Cancer Res (2004) 64 (11): 3885–3891.
https://doi.org/10.1158/0008-5472.CAN-03-2818
Published: 01 June 2004
View article titled, Cyclin-Dependent Kinase Inhibition by the KLF6 Tumor Suppressor Protein through Interaction with Cyclin D1
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Journal Articles

Phosphorylation of Retinoid X Receptor α at Serine 260 Impairs Its Metabolism and Function in Human Hepatocellular Carcinoma

Rie Matsushima-Nishiwaki, Masataka Okuno, Seiji Adachi, Tetsuro Sano, Kuniharu Akita, Hisataka Moriwaki, Scott L. Friedman, Soichi Kojima
Journal: Cancer Research
Cancer Res (2001) 61 (20): 7675–7682.
Published: 01 October 2001
View article titled, Phosphorylation of Retinoid X Receptor α at Serine 260 Impairs Its Metabolism and Function in Human Hepatocellular Carcinoma
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Journal Articles

p53 Does Not Repress Hypoxia-induced Transcription of the Vascular Endothelial Growth Factor Gene

Faton Agani, David G. Kirsch, Scott L. Friedman, Michael B. Kastan, Gregg L. Semenza
Journal: Cancer Research
Cancer Res (1997) 57 (20): 4474–4477.
Published: 01 October 1997
View article titled, p53 Does Not Repress Hypoxia-induced Transcription of the Vascular Endothelial Growth Factor Gene
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