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Scott A. Tomlins
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Journal Articles

Abstract 2038: Antibody Drug Conjugates Treatment Response Score (ADC TRS) for predicting ADC treatment response

Sachdev P. Thomas, Laurel A. Habel, Jennifer M. Suga, Ninah Achacoso, Joshua R. Nugent, Chen Jiang, Elaine Chung, Stephanie Bush, Michael D. Nitchie, Katarina M. Robinson, Jasie Inman, Ryan White, Komal Plouffe, Daniel R. Rhodes, Scott A. Tomlins, Bryan Johnson
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2038.
https://doi.org/10.1158/1538-7445.AM2025-2038
Published: 21 April 2025
View articletitled, Abstract 2038: Antibody Drug Conjugates Treatment Response Score (ADC TRS) for predicting ADC treatment response
Journal Articles

Abstract CT059: StrataPATHTM: a multicohort, non-randomized, open-label phase 2 trial to explore efficacy and safety of FDA-approved cancer therapies in novel biomarker-guided patient population

Kat Kwiatkowski, Laura E. Lamb, Scott A. Tomlins, D. Brian Johnson, Daniel H. Hovelson, Nickolay Khazanov, Benjamin J. Bulen, Travis Reeder, Daniel R. Rhodes
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT059.
https://doi.org/10.1158/1538-7445.AM2023-CT059
Published: 14 April 2023
View articletitled, Abstract CT059: StrataPATHTM: a multicohort, non-randomized, open-label phase 2 trial to explore efficacy and safety of FDA-approved cancer therapies in novel biomarker-guided patient population
Journal Articles

Abstract 5595: Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance

Andi K. Cani, Emily M. Dolce, Kevin Hu, Chia-Jen Liu, Elizabeth P. Darga, Dan Robinson, Yi-Mi Wu, Dafydd G. Thomas, Costanza Paoletti, Scott A. Tomlins, James M. Rae, Aaron M. Udager, Arul M. Chinnaiyan, Erin F. Cobain, Daniel F. Hayes
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5595.
https://doi.org/10.1158/1538-7445.AM2023-5595
Published: 04 April 2023
View articletitled, Abstract 5595: Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance
Journal Articles

Abstract 2171: A multivariate biomarker predicts sacituzumab govitecan response in solid tumors

Nickolay A. Khazanov, Laura E. Lamb, Daniel H. Hovelson, Kat Kwiatkowski, D. Bryan Johnson, Daniel R. Rhodes, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2171.
https://doi.org/10.1158/1538-7445.AM2023-2171
Published: 04 April 2023
View articletitled, Abstract 2171: A multivariate biomarker predicts sacituzumab govitecan response in solid tumors
Journal Articles

Abstract 4348: Validation of an integrative pan-solid tumor predictor of pembrolizumab monotherapy benefit

Benjamin J. Bulen, Nickolay A. Khazanov, Laura E. Lamb, Daniel H. Hovelson, Kat Kwiatkowski, D. Bryan Johnson, Daniel R. Rhodes, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4348.
https://doi.org/10.1158/1538-7445.AM2023-4348
Published: 04 April 2023
View articletitled, Abstract 4348: Validation of an integrative pan-solid tumor predictor of pembrolizumab monotherapy benefit
Journal Articles

Abstract 968: Evaluation of Her2 RNA expression as a potential predictive biomarker for anti-Her2 therapy

Laura E. Lamb, Nickolay A. Khazanov, Daniel H. Hovelson, Kat Kwiatkowski, D. Bryan Johnson, Daniel R. Rhodes, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 968.
https://doi.org/10.1158/1538-7445.AM2023-968
Published: 04 April 2023
View articletitled, Abstract 968: Evaluation of Her2 RNA expression as a potential predictive biomarker for anti-Her2 therapy
Journal Articles

Abstract 1700: Serial monitoring of single-cell circulating tumor cell genomics in metastatic lobular breast cancer to identify precision and immuno-oncology biomarkers with therapeutic implications

Andi K. Cani, Emily M. Dolce, Elizabeth P. Darga, Kevin Hu, Chia-Jen Liu, James M. Rae, Daffyd G. Thomas, Scott A. Tomlins, Arul M. Chinnaiyan, Aaron M. Udager, Costanza Paoletti, Erin F. Cobain, Daniel F. Hayes
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1700.
https://doi.org/10.1158/1538-7445.AM2022-1700
Published: 15 June 2022
View articletitled, Abstract 1700: Serial monitoring of single-cell circulating tumor cell genomics in metastatic lobular breast cancer to identify precision and immuno-oncology biomarkers with therapeutic implications
Journal Articles

Abstract 611: Assessment of tumor mutation burden and microsatellite instability by single-cell circulating tumor cell genomic profiling

Andi K. Cani, Emily M. Dolce, Chia-Jen Liu, Brittany Rupp, Elizabeth P. Darga, Costanza Paoletti, Dafydd G. Thomas, Yi-Mi Wu, Dan R. Robinson, Sunitha Nagrath, Arul M. Chinnaiyan, Scott A. Tomlins, Aaron M. Udager, John M. Carethers, Erin F. Cobain, Daniel F. Hayes
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 611.
https://doi.org/10.1158/1538-7445.AM2022-611
Published: 15 June 2022
View articletitled, Abstract 611: Assessment of tumor mutation burden and microsatellite instability by single-cell circulating tumor cell genomic profiling
Journal Articles

Abstract 3143: Monitoring circulating tumor cell (CTC) and circulating tumor DNA (ctDNA) genomic alterations in ER positive (POS)/HER2 negative (NEG) advanced breast cancer during endocrine therapy: correlative study of AZD9496 oral SERD phase I trial

Andi K. Cani, Emily M. Dolce, Elizabeth P. Darga, Kevin Hu, Martha Brown, Chia-Jen Liu, Jackie Pierce, Kieran Bradbury, Kimberly Aung, Gaia Schiavon, Danielle Carroll, T. H. Carr, Teresa Klinowska, Justin Lindemann, Gayle Marshall, Vicky Rowlands, Elizabeth A. Harrington, J. Barrett, Anne Armstrong, Richard Baird, Erika Hamilton, Seock-Ah Im, Komal Jhaveri, Manish R. Patel, Caroline Dive, Scott A. Tomlins, Aaron M. Udager, Daniel F. Hayes, Costanza Paoletti
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3143.
https://doi.org/10.1158/1538-7445.AM2021-3143
Published: 01 July 2021
View articletitled, Abstract 3143: Monitoring circulating tumor cell (CTC) and circulating tumor DNA (ctDNA) genomic alterations in ER positive (POS)/HER2 negative (NEG) advanced breast cancer during endocrine therapy: correlative study of AZD9496 oral SERD phase I trial
Journal Articles

Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts

Kevin W. McCool, Zachary T. Freeman, Yali Zhai, Rong Wu, Kevin Hu, Chia-Jen Liu, Scott A. Tomlins, Eric R. Fearon, Brian Magnuson, Rork Kuick, Kathleen R. Cho
Journal: Cancer Research
Cancer Res (2020) 80 (4): 877–889.
https://doi.org/10.1158/0008-5472.CAN-19-2558
Published: 14 February 2020
View articletitled, Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts
Open the PDF for Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts in another window
Includes: Supplementary data
Journal Articles

Abstract 914: Development of a whole-urine, next-generation sequencing-based assay for early detection of aggressive prostate cancer

Andi K. Cani, Kevin Hu, Javed Siddiqui, Sumin Han, Daniel H. Hovelson, Chia-Jen Liu, Simpa S. Salami, Ganesh S. Palapattu, Todd M. Morgan, John T. Wei, Arul M. Chinnaiyan, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 914.
https://doi.org/10.1158/1538-7445.AM2019-914
Published: 01 July 2019
View articletitled, Abstract 914: Development of a whole-urine, next-generation sequencing-based assay for early detection of aggressive prostate cancer
Journal Articles

Abstract B036: Comprehensive transcriptomic profiling challenges the robustness of prostate cancer prognostic signatures to multifocality

Simpa Salami, Daniel H. Hovelson, Jeremy B. Kaplan, Romain Mathieu, Aaron M. Udager, Nicole Curci, Matthew Lee, Lorena Lazo de la Vega, Martin Susani, Nathalie Rioux-Leclercq, Daniel E. Spratt, Todd M. Morgan, Matthew S. Davenport, Mark A. Rubin, Shariat F. Shahrokh, Scott A. Tomlins, Ganesh S. Palapattu
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): B036.
https://doi.org/10.1158/1538-7445.PRCA2017-B036
Published: 14 August 2018
View articletitled, Abstract B036: Comprehensive transcriptomic profiling challenges the robustness of prostate cancer prognostic signatures to multifocality
Journal Articles

Abstract IA08: Early detection of high-risk localized prostate cancer

Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): IA08.
https://doi.org/10.1158/1538-7445.PRCA2017-IA08
Published: 14 August 2018
View articletitled, Abstract IA08: Early detection of high-risk localized prostate cancer
Journal Articles

Abstract LB-118: A conserved checkpoint molecule signature offers novel targets for tumor specific regulatory T cell manipulation

Zachary T. Freeman, Daniel H. Hovleson, Alexander T. Pearson, Jingyi Zhai, Ali Ghasemzadeh, Thomas R. Nirschl, Hui Jiang, Scott A. Tomlins, Charles G. Drake
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-118.
https://doi.org/10.1158/1538-7445.AM2018-LB-118
Published: 01 July 2018
View articletitled, Abstract LB-118: A conserved checkpoint molecule signature offers novel targets for tumor specific regulatory T cell manipulation
Journal Articles

The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer

Prasanna Ekambaram, Jia-Ying (Lloyd) Lee, Nathaniel E. Hubel, Dong Hu, Saigopalakrishna Yerneni, Phil G. Campbell, Netanya Pollock, Linda R. Klei, Vincent J. Concel, Phillip C. Delekta, Arul M. Chinnaiyan, Scott A. Tomlins, Daniel R. Rhodes, Nolan Priedigkeit, Adrian V. Lee, Steffi Oesterreich, Linda M. McAllister-Lucas, Peter C. Lucas
Journal: Cancer Research
Cancer Res (2018) 78 (5): 1225–1240.
https://doi.org/10.1158/0008-5472.CAN-17-1089
Published: 28 February 2018
View articletitled, The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer
Open the PDF for The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Comprehensive Mutation and Copy Number Profiling in Archived Circulating Breast Cancer Tumor Cells Documents Heterogeneous Resistance Mechanisms

Costanza Paoletti, Andi K. Cani, Jose M. Larios, Daniel H. Hovelson, Kimberly Aung, Elizabeth P. Darga, Emily M. Cannell, Paul J. Baratta, Chia-Jen Liu, David Chu, Maryam Yazdani, Allen R. Blevins, Valeria Sero, Nahomi Tokudome, Dafydd G. Thomas, Christina Gersch, Anne F. Schott, Yi-Mi Wu, Robert Lonigro, Dan R. Robinson, Arul M. Chinnaiyan, Farideh Z. Bischoff, Michael D. Johnson, Ben H. Park, Daniel F. Hayes, James M. Rae, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2018) 78 (4): 1110–1122.
https://doi.org/10.1158/0008-5472.CAN-17-2686
Published: 14 February 2018
View articletitled, Comprehensive Mutation and Copy Number Profiling in Archived Circulating Breast Cancer Tumor Cells Documents Heterogeneous Resistance Mechanisms
Open the PDF for Comprehensive Mutation and Copy Number Profiling in Archived Circulating Breast Cancer Tumor Cells Documents Heterogeneous Resistance Mechanisms in another window
Includes: Supplementary data
Journal Articles

Abstract 1447: Identification of an oncogenic germline KRAS truncating mutation in hereditary cancers

Moloy T. Goswami, Daniel H. Hovelson, Anna Johnson, Scott A. Tomlins, Lucy Wang, Kimberly Zhulke, Bhavneet Singh, Sharath Kumar Anand, Andi Cani, Albert Liu, Steven Kamberov, Yi-Mi Wu, Dan Robinson, Arul Chinnaiyan, Kathleen A. Cooney
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1447.
https://doi.org/10.1158/1538-7445.AM2017-1447
Published: 01 July 2017
View articletitled, Abstract 1447: Identification of an oncogenic germline KRAS truncating mutation in hereditary cancers
Journal Articles

Abstract 692: Identifying genes that regulate bladder cancer progression and invasion

Amy L. Han, Brendan Veeneman, Scott A. Tomlins, Evan T. Keller
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 692.
https://doi.org/10.1158/1538-7445.AM2016-692
Published: 15 July 2016
View articletitled, Abstract 692: Identifying genes that regulate bladder cancer progression and invasion
Journal Articles

Abstract 3151: Genetic profiling of circulating tumor cells (CTC) in metastatic breast cancer (MBC) patients

Costanza Paoletti, Andi K. Cani, Kimberly Aung, Elizabeth P. Darga, Emily M. Cannell, Daniel H. Hovelson, Maryam Yazdani, Allen R. Blevins, Nahomi Tokudome, Paul J. Baratta, Jose’ M. Larios, Dafydd G. Thomas, Martha E. Brown, Christina Gersch, Anne F. Schott, Daniel Robinson, Arul M. Chinnaiyan, Farideh Bischoff, Daniel F. Hayes, James M. Rae, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3151.
https://doi.org/10.1158/1538-7445.AM2016-3151
Published: 15 July 2016
View articletitled, Abstract 3151: Genetic profiling of circulating tumor cells (CTC) in metastatic breast cancer (MBC) patients
Journal Articles

Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy

Andrew S. McDaniel, Daniel H. Hovelson, Andi K. Cani, Chia-Jen Liu, Yali Zhai, Yajia Zhang, Alon Z. Weizer, Rohit Mehra, Felix Y. Feng, Ajjai S. Alva, Todd M. Morgan, Jeffrey S. Montgomery, Javed Siddiqui, Seth Sadis, Santhoshi Bandla, Paul D. Williams, Kathleen R. Cho, Daniel R. Rhodes, Scott A. Tomlins
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5219–5227.
https://doi.org/10.1158/0008-5472.CAN-15-1004
Published: 14 December 2015
View articletitled, Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy
Open the PDF for Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy in another window
Includes: Supplementary data