1-20 of 82
Saraswati Sukumar
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Nanoparticle-Based Combination Therapy Enhances Fulvestrant Efficacy and Overcomes Tumor Resistance in ER-Positive Breast Cancer

Bozhao Li, Feilong Qi, Fei Zhu, Zefang Lu, Meiqi Wang, Tianjiao Chu, Suying Wu, Jingyan Wei, Zhenchuan Song, Saraswati Sukumar, Cheng Zhang, Jiangfei Xu, Suping Li, Guangjun Nie
Journal: Cancer Research
Cancer Res (2023) 83 (17): 2924–2937.
https://doi.org/10.1158/0008-5472.CAN-22-3559
Published: 01 September 2023
View article titled, Nanoparticle-Based Combination Therapy Enhances Fulvestrant Efficacy and Overcomes Tumor Resistance in ER-Positive Breast Cancer
Open the PDF for Nanoparticle-Based Combination Therapy Enhances Fulvestrant Efficacy and Overcomes Tumor Resistance in ER-Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial

Kala Visvanathan, Leslie Cope, Mary Jo Fackler, Michael Considine, Lisa Carey, Andres Forero-Torres, James N. Ingle, Nancy U. Lin, Rita Nanda, Anna Maria Storniolo, Suzana Tulac, Natalie C. Wu, Sudhakar Marla, Neesha R. Venkatesan, Antonio C. Wolff, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-02-09.
https://doi.org/10.1158/1538-7445.SABCS22-P4-02-09
Published: 01 March 2023
View article titled, Abstract P4-02-09: Evaluation of the Automated Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC-005 Prospective Trial
Journal Articles

HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells

Priya Pai, Guannan Wang, Wei Wen Teo, Diana Raez-Rodriguez, Kathleen L. Gabrielson, Balázs Győrffy, Bradley M. Downs, Akanksha Aggarwal, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2022) 82 (20): 3802–3814.
https://doi.org/10.1158/0008-5472.CAN-21-4277
Published: 17 October 2022
View article titled, HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells
Open the PDF for HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells in another window
Includes: Supplementary data
Journal Articles

Abstract P5-08-03: Intraductal administration of a Transferrin Receptor-directed immunotoxin eliminates ductal carcinoma in situ in preclinical mammary in-duct (MIND) models of breast cancer

Saraswati Sukumar, Guannan Wang, Alok Kumar, Wanjun Ding, Preethi Korangath, Priya Pai, Kathleen Gabrielson, Ira Pastan
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-08-03.
https://doi.org/10.1158/1538-7445.SABCS21-P5-08-03
Published: 15 February 2022
View article titled, Abstract P5-08-03: Intraductal administration of a Transferrin Receptor-directed immunotoxin eliminates ductal carcinoma in situ in preclinical mammary in-duct (MIND) models of breast cancer
Journal Articles

Abstract PS4-03: An automated DNA methylation assay for monitoring treatment response in patients with metastatic breast cancer

Mary Jo Fackler, Suzana Tulac, Neesha Venkatesan, Adam J. Aslam, Leslie M. Cope, Jennifer Lehman, Rita Denbow, Jeffrey Reynolds, Morgan Buckley, Bradley M. Downs, Kala Visvanathan, Christopher B. Umbricht, Antonio C. Wolff, Vered Stearns, Edwin W. Lai, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-03.
https://doi.org/10.1158/1538-7445.SABCS20-PS4-03
Published: 15 February 2021
View article titled, Abstract PS4-03: An automated DNA methylation assay for monitoring treatment response in patients with metastatic breast cancer
Journal Articles

Abstract P3-06-01: Junctional adhesion molecule-A (JAM-A) as a novel future drug target in ductal carcinoma in situ (DCIS)

Ann M Hopkins, Yvonne E. Smith, Guannan Wang, Ciara Flynn, Alexander Casucci, Sri HariKrishna Vellanki, Lance Hudson, Kieran Brennan, Mattia Cremona, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-06-01.
https://doi.org/10.1158/1538-7445.SABCS19-P3-06-01
Published: 15 February 2020
View article titled, Abstract P3-06-01: Junctional adhesion molecule-A (JAM-A) as a novel future drug target in ductal carcinoma <em>in situ</em> (DCIS)
Journal Articles

Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients

Juanjuan Li, Bradley Downs, Leslie Cope, Xiuyun Zhang, Chuan-gui Song, Kejing Zhang, Yong Han, Mary Jo Fackler, Edwin Lai, Suzana Tulac, Neesha Venkatesan, Timothy Guzman, Chuang Chen, Jingping Yuan, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-02-06.
https://doi.org/10.1158/1538-7445.SABCS19-P4-02-06
Published: 15 February 2020
View article titled, Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients
Journal Articles

Abstract 3475: Suppression of inflammatory signaling by HOXA5 via modulation of the NF-KB pathway in breast cancer

Priya Pai, Guannan Wang, Diana Ráez Rodríguez, Wayne Yu, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3475.
https://doi.org/10.1158/1538-7445.AM2019-3475
Published: 01 July 2019
View article titled, Abstract 3475: Suppression of inflammatory signaling by HOXA5 via modulation of the NF-KB pathway in breast cancer
Journal Articles

Abstract 1388: A novel Hyper-Methylation Outlier method for blood biomarker discovery

Bradley M. Downs, Juanjuan Li, Mary Jo Fackler, Antonio C. Wolff, Saraswati Sukumar, Chris B. Umbricht, Leslie M. Cope
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1388.
https://doi.org/10.1158/1538-7445.AM2019-1388
Published: 01 July 2019
View article titled, Abstract 1388: A novel Hyper-Methylation Outlier method for blood biomarker discovery
Journal Articles

Abstract 2649: A novel approach to fate-map hypoxic cells during tumor progression uncovers metastatic potency of post-hypoxic cells

Inês Godet, Yu Jung Shin, Julia A. Ju, Soumitra Bhoyar, I Chae Ye, Guannan Wang, Saraswati Sukumar, Daniele M. Gilkes
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2649.
https://doi.org/10.1158/1538-7445.AM2019-2649
Published: 01 July 2019
View article titled, Abstract 2649: A novel approach to fate-map hypoxic cells during tumor progression uncovers metastatic potency of post-hypoxic cells
Journal Articles

Abstract LB-220: An automated breast cancer detection assay for screening in the developing world

Bradley M. Downs, Mary Jo Fackler, Claudia Mercado-Rodriguez, Ashley Cimino-Mathews, Chuang Chen, Jing-Ping Yuan, Eunice van den Berg, Leslie M. Cope, Susan C. Harvey, Syed Z. Ali, Suzana Tulac, Kriszten J. Kocmond, Edwin W. Lai, Brian Rhees, Mike Bates, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-220.
https://doi.org/10.1158/1538-7445.AM2018-LB-220
Published: 01 July 2018
View article titled, Abstract LB-220: An automated breast cancer detection assay for screening in the developing world
Journal Articles

Abstract 4467: The role of HOXA5 in the malignant progression of engineered isogenic MCF10A sublines harboring common breast cancer mutations

Priya Pai, Guannan Wang, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4467.
https://doi.org/10.1158/1538-7445.AM2018-4467
Published: 01 July 2018
View article titled, Abstract 4467: The role of HOXA5 in the malignant progression of engineered isogenic MCF10A sublines harboring common breast cancer mutations
Journal Articles

HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells

Helen Sadik, Preethi Korangath, Nguyen K. Nguyen, Balazs Gyorffy, Rakesh Kumar, Mohammad Hedayati, Wei Wen Teo, Sunju Park, Hardik Panday, Teresa Gonzalez Munoz, Otilia Menyhart, Nilay Shah, Raj K. Pandita, Jenny C. Chang, Theodore DeWeese, Howard Y. Chang, Tej K. Pandita, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2016) 76 (15): 4443–4456.
https://doi.org/10.1158/0008-5472.CAN-16-0774
Published: 31 July 2016
View article titled, HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells
Open the PDF for HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

The Widening Sphere of Influence of HOXB7 in Solid Tumors

Maria Cristina Errico, Kideok Jin, Saraswati Sukumar, Alessandra Carè
Journal: Cancer Research
Cancer Res (2016) 76 (10): 2857–2862.
https://doi.org/10.1158/0008-5472.CAN-15-3444
Published: 12 May 2016
View article titled, The Widening Sphere of Influence of HOXB7 in Solid Tumors
Open the PDF for The Widening Sphere of Influence of HOXB7 in Solid Tumors in another window
Journal Articles

Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer

Vanessa F. Merino, Nguyen Nguyen, Kideok Jin, Helen Sadik, Soonweng Cho, Preethi Korangath, Liangfeng Han, Yolanda M.N. Foster, Xian C. Zhou, Zhe Zhang, Roisin M. Connolly, Vered Stearns, Syed Z. Ali, Christina Adams, Qian Chen, Duojia Pan, David L. Huso, Peter Ordentlich, Angela Brodie, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2016) 76 (7): 2013–2024.
https://doi.org/10.1158/0008-5472.CAN-15-1619
Published: 31 March 2016
View article titled, Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer
Open the PDF for Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1526: HOXA5 inhibits cell plasticity and stemness in breast cancer cells by reinforcing epithelial traits

Wei Wen Teo, Vanessa Merino, Sean Cho, Preethi Korangath, Neil M. Neumann, Andrew J. Ewald, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1526.
https://doi.org/10.1158/1538-7445.AM2015-1526
Published: 01 August 2015
View article titled, Abstract 1526: HOXA5 inhibits cell plasticity and stemness in breast cancer cells by reinforcing epithelial traits
Journal Articles

Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer

Vanessa F. Merino, Nguyen Nguyen, Helen Sadik, Soonweng Cho, Leslie Cope, Xian C. Zhou, Zhe Zhang, Qian Chen, Duojia Pan, David L. Huso, Syed Ali, Christina Adams, Balázs Győrffy, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4231.
https://doi.org/10.1158/1538-7445.AM2015-4231
Published: 01 August 2015
View article titled, Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer
Journal Articles

HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway

Shou Liu, Kideok Jin, Yvonne Hui, Jie Fu, Chunfa Jie, Sheng Feng, David Reisman, Qian Wang, Daping Fan, Saraswati Sukumar, Hexin Chen
Journal: Cancer Research
Cancer Res (2015) 75 (4): 709–719.
https://doi.org/10.1158/0008-5472.CAN-14-3100
Published: 15 February 2015
View article titled, HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway
Open the PDF for HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk

Liangfeng Han, Adam Diehl, Nguyen K. Nguyen, Preethi Korangath, Weiwen Teo, Soonweng Cho, Scott Kominsky, David L. Huso, Lionel Feigenbaum, Alan Rein, Pedram Argani, Goran Landberg, Manfred Gessler, Saraswati Sukumar
Journal: Cancer Research
Cancer Res (2014) 74 (22): 6509–6518.
https://doi.org/10.1158/0008-5472.CAN-14-0816
Published: 13 November 2014
View article titled, The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk
Open the PDF for The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk in another window
Includes: Supplementary data
Journal Articles

Abstract 443: Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib

Paweena Chalugun, Joong Sup Shim, Preethi C. Korangath, Saraswati Sukumar, Jun O. Liu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 443.
https://doi.org/10.1158/1538-7445.AM2014-443
Published: 01 October 2014
View article titled, Abstract 443: Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib