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Sara Ladu
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Journal Articles

Abstract 4300: The EEF1A2-PI3K-AKT-mTOR axis supports the protumorigenic function of MDM4 in human hepatocellular carcinoma.

Rossella Pellegrino, Diego F. Calvisi, Olaf Neumann, Xin Chen, Chunmei Wang, Bernhard Radlwimmer, Sara Ladu, Frank Dombrowski, Matthias Evert, Peter Schirmacher, Thomas Longerich
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4300.
https://doi.org/10.1158/1538-7445.AM2013-4300
Published: 15 April 2013
View article titled, Abstract 4300: The EEF1A2-PI3K-AKT-mTOR axis supports the protumorigenic function of MDM4 in human hepatocellular carcinoma.
Journal Articles

Abstract 1068: Downregulation of PH domain leucine-rich repeat protein phosphatases (PHLPPs) identifies a subgroup of human hepatocellular and colorectal carcinomas with elevated levels of activated AKT and low apoptosis rate

Sara Ladu, Tommaso Staniscia, Di Renzo Raffaella M, Bongarzoni Giuseppe, Ferdinando Romano, Diego F Calvisi
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1068.
https://doi.org/10.1158/1538-7445.AM2011-1068
Published: 15 April 2011
View article titled, Abstract 1068: Downregulation of PH domain leucine-rich repeat protein phosphatases (PHLPPs) identifies a subgroup of human hepatocellular and colorectal carcinomas with elevated levels of activated AKT and low apoptosis rate
Journal Articles

Dual-Specificity Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase–Mediated Control of Growth in Human Hepatocellular Carcinoma

Diego F. Calvisi, Federico Pinna, Floriana Meloni, Sara Ladu, Rossella Pellegrino, Marcella Sini, Lucia Daino, Maria M. Simile, Maria R. De Miglio, Patrizia Virdis, Maddalena Frau, Maria L. Tomasi, Maria A. Seddaiu, Maria R. Muroni, Francesco Feo, Rosa M. Pascale
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4192–4200.
https://doi.org/10.1158/0008-5472.CAN-07-6157
Published: 02 June 2008
View article titled, Dual-Specificity Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase–Mediated Control of Growth in Human Hepatocellular Carcinoma
Open the PDF for Dual-Specificity Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase–Mediated Control of Growth in Human Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Molecular pathogenesis of human hepatocellular carcinoma: Mechanistic and prognostic significance of aberrant methylation

Diego F. Calvisi, Sara Ladu, Alexis Gorden, Miriam Farina, Ju-Seog Lee, Elizabeth A. Conner, Insa S. Schroeder, Valentina M. Factor, Snorri S. Thorgeirsson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 763.
Published: 15 April 2006
View article titled, Molecular pathogenesis of human hepatocellular carcinoma: Mechanistic and prognostic significance of aberrant methylation
Journal Articles

Transgenic mouse models of liver cancer recapitulate the aberrant pattern of DNA methylation in human hepatocellular carcinoma.

Sara Ladu, Diego F. Calvisi, Miriam Farina, Elizabeth A. Conner, Aranzazu Sanchez, Valentina M. Factor, Snorri S. Thorgeirsson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1200.
Published: 15 April 2006
View article titled, Transgenic mouse models of liver cancer recapitulate the aberrant pattern of DNA methylation in human hepatocellular carcinoma.
Journal Articles

Combined silencing of Ras and Jak/Stat inhibitors results in constitutive activation of Ras and Jak/Stat pathways in human hepatocellular carcinoma

Diego F. Calvisi, Sara Ladu, Alexis Gorden, Valentina M. Factor, Snorri S. Thorgeirsson
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 610.
Published: 01 May 2005
View article titled, Combined silencing of Ras and Jak/Stat inhibitors results in constitutive activation of Ras and Jak/Stat pathways in human hepatocellular carcinoma
Journal Articles

Co-expression of c-Myc and E2F1 in a mouse model of liver cancer suppresses apoptosis through activation of Akt/mTOR/p70S6K and COX-2 pathways: relevance for human hepatocellular carcinoma

Sara Ladu, Diego F. Calvisi, Elizabeth A. Conner, Valentina M. Factor, Snorri S. Thorgeirsson
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 258.
Published: 01 May 2005
View article titled, Co-expression of c-Myc and E2F1 in a mouse model of liver cancer suppresses apoptosis through activation of Akt/mTOR/p70S6K and COX-2 pathways: relevance for human hepatocellular carcinoma
Journal Articles

Activation of c-Myc and E2F-1 cooperates with Wnt signaling pathway to accelerate liver cancer development in transgenic mice

Elizabeth A. Conner, Diego F. Calvisi, Sara Ladu, Eric R. Lemmer, Valentina M. Factor, Snorri S. Thorgeirsson
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 994.
Published: 01 April 2004
View article titled, Activation of c-Myc and E2F-1 cooperates with Wnt signaling pathway to accelerate liver cancer development in transgenic mice
Journal Articles

Chromosome Mapping of Multiple Loci Affecting the Genetic Predisposition to Rat Liver Carcinogenesis

Maria R. De Miglio, Rosa M. Pascale, Maria M. Simile, Maria R. Muroni, Diego F. Calvisi, Patrizia Virdis, Giovanni M. Bosinco, Maddalena Frau, Maria A. Seddaiu, Sara Ladu, Francesco Feo
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4459–4463.
Published: 01 August 2002
View article titled, Chromosome Mapping of Multiple Loci Affecting the Genetic Predisposition to Rat Liver Carcinogenesis
Open the PDF for Chromosome Mapping of Multiple Loci Affecting the Genetic Predisposition to Rat Liver Carcinogenesis in another window