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Sandra Hervas-Stubbs
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Journal Articles

Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells

Inaki Etxeberria, Elixabet Bolaños, Alvaro Teijeira, Arantza Azpilicueta, Jose Ignacio Quetglas, Alfonso Rodriguez Sanchez-Paulete, Itziar Otano, Uxua Mancheño, Sandra Hervas-Stubbs, Susana Inoges, Saray Garasa, Maite Alvarez, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2331.
https://doi.org/10.1158/1538-7445.AM2019-2331
Published: 01 July 2019
View article titled, Abstract 2331: Intratumor adoptive transfer of IL-12 mRNA transiently engineered anti-tumor CD8+ T cells
Journal Articles

Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy

Sarita M. Fernandez-Poma, Diego Salas-Benito, Teresa Lozano, Noelia Casares, Jose-Ignacio Riezu-Boj, Uxua Mancheño, Edurne Elizalde, Diego Alignani, Natalia Zubeldia, Itziar Otano, Enrique Conde, Pablo Sarobe, Juan Jose Lasarte, Sandra Hervas-Stubbs
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3672–3684.
https://doi.org/10.1158/0008-5472.CAN-17-0236
Published: 02 July 2017
View article titled, Expansion of Tumor-Infiltrating CD8<sup>+</sup> T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy
Open the PDF for Expansion of Tumor-Infiltrating CD8<sup>+</sup> T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy in another window
Includes: Supplementary data
Journal Articles

Strict Requirement for Vector-Induced Type I Interferon in Efficacious Antitumor Responses to Virally Encoded IL12

Ignacio Melero, Jose I. Quetglas, Mercedes Reboredo, Juan Dubrot, Juan R. Rodriguez-Madoz, Uxua Mancheño, Erkuden Casales, Jose I. Riezu-Boj, Marta Ruiz-Guillen, Maria C. Ochoa, Miguel F. Sanmamed, Nathalie Thieblemont, Cristian Smerdou, Sandra Hervas-Stubbs
Journal: Cancer Research
Cancer Res (2015) 75 (3): 497–507.
https://doi.org/10.1158/0008-5472.CAN-13-3356
Published: 01 February 2015
View article titled, Strict Requirement for Vector-Induced Type I Interferon in Efficacious Antitumor Responses to Virally Encoded IL12
Open the PDF for Strict Requirement for Vector-Induced Type I Interferon in Efficacious Antitumor Responses to Virally Encoded IL12 in another window
Includes: Supplementary data
Journal Articles

Abstract LB-330: Therapeutic activity of a combination of immunostimulatory monoclonal antibodies (anti-B7-H1, CD137 and OX40) on a c-myc-driven spontaneous transgenic model of hepatocellular carcinoma.

Aizea Morales-Kastresana, Miguel F. Sanmamed, Inmaculada Rodriguez, Asis Palazon, Ivan Martinez-Forero, Sara Labiano, Sandra Hervas-Stubbs, Bruno Sangro, Carmen Ochoa, Arantza Azpilikueta, Elixabet Bolaños, Ines Gütgemann, Ignacio Melero
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-330.
https://doi.org/10.1158/1538-7445.AM2013-LB-330
Published: 15 April 2013
View article titled, Abstract LB-330: Therapeutic activity of a combination of immunostimulatory monoclonal antibodies (anti-B7-H1, CD137 and OX40) on a c-myc-driven spontaneous transgenic model of hepatocellular carcinoma.
Journal Articles

Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein

Maria C. Ochoa, Jessica Fioravanti, Inmaculada Rodriguez, Sandra Hervas-Stubbs, Arantza Azpilikueta, Guillermo Mazzolini, Alfonso Gúrpide, Jesus Prieto, Julian Pardo, Pedro Berraondo, Ignacio Melero
Journal: Cancer Research
Cancer Res (2013) 73 (1): 139–149.
https://doi.org/10.1158/0008-5472.CAN-12-2660
Published: 02 January 2013
View article titled, Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein
Open the PDF for Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein in another window
Includes: Supplementary data
Journal Articles

Abstract 3538: The HIF-1α hypoxia response in mouse tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy

Asis Palazon, Ivan Martinez-forero, Alvaro Teijeira, Aizea Morales-Kastresana, Carlos Alfaro, Miguel Fernandez de Sanmamed, Sandra Hervas-Stubbs, Maria Jure-Kunkel, Julian Aragones, Ignacio Melero
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3538.
https://doi.org/10.1158/1538-7445.AM2012-3538
Published: 15 April 2012
View article titled, Abstract 3538: The HIF-1α hypoxia response in mouse tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Journal Articles

Agonist Anti-CD137 mAb Act on Tumor Endothelial Cells to Enhance Recruitment of Activated T Lymphocytes

Asís Palazón, Alvaro Teijeira, Iván Martínez-Forero, Sandra Hervás-Stubbs, Carmen Roncal, Iván Peñuelas, Juan Dubrot, Aizea Morales-Kastresana, José Luis Pérez-Gracia, M. Carmen Ochoa, Laura Ochoa-Callejero, Alfredo Martínez, Alfonso Luque, Joseph Dinchuk, Ana Rouzaut, Maria Jure-Kunkel, Ignacio Melero
Journal: Cancer Research
Cancer Res (2011) 71 (3): 801–811.
https://doi.org/10.1158/0008-5472.CAN-10-1733
Published: 01 February 2011
View article titled, Agonist Anti-CD137 mAb Act on Tumor Endothelial Cells to Enhance Recruitment of Activated T Lymphocytes
Open the PDF for Agonist Anti-CD137 mAb Act on Tumor Endothelial Cells to Enhance Recruitment of Activated T Lymphocytes in another window
Includes: Supplementary data
Journal Articles

Abstract #4134: Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-\#945;

Ana Rouzaut, Saray Garasa, Alvaro Teijeira, Ivan Martínez-Forero, Iranzo Martínez-González, Esther Larrea, Carlos Alfaro, Asís Palazón, Juan Dubrot, Sandra Hervás-Stubbs, Ignacio Melero
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4134.
Published: 01 May 2009
View article titled, Abstract #4134: Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-\#945;
Journal Articles

Abstract #2413: Intratumoral injection of interferon-\#945; and systemic delivery of agonist anti-CD137 mAb synergize for immunotherapy in mice bearing multiple tumor lesions.

Juan Dubrot, Asis Palazon, Carmen Ochoa, Carlos Alfaro, Arantza Azpilikueta, Natalia Suarez, Ana Rouzaut, Ivan Marinez Forero, Jose L. Perez-Gracia, Aganes Le Bon, Sandra Hervas-Stubbs, Ignacio Melero
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2413.
Published: 01 May 2009
View article titled, Abstract #2413: Intratumoral injection of interferon-\#945; and systemic delivery of agonist anti-CD137 mAb synergize for immunotherapy in mice bearing multiple tumor lesions.
Journal Articles

Involvement but not absolute requirement of Dendritic cell-mediated crosspriming for immunotherapy with agonist anti-CD137 monoclonal antibodies

Oihana Murillo, Ainhoa Arina, Juan Dubrot, Sandra Hervas-Stubbs, Ignacio Melero
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2087.
Published: 01 May 2008
View article titled, Involvement but not absolute requirement of Dendritic cell-mediated crosspriming for immunotherapy with agonist anti-CD137 monoclonal antibodies