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Sandhya Mandlekar
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Journal Articles

Abstract CT029: Phase Ib study of GDC-6036 in combination with cetuximab in patients with colorectal cancer (CRC) with KRAS G12C mutation

Jayesh Desai, Sae-Won Han, Jong-Seok Lee, Einat Shacham-Shmueli, Erminia Massarelli, Andrés Cervantes, Elena Garralda, Alejandro Falcon, Wilson H. Miller, Eelke Gort, Thomas Karasic, Salvatore Siena, Rafal Stec, Laura Medina, Luis Paz-Arez, Angelo Delmonte, Adrian Sacher, Hans Prenen, Martin Forster, Tae Won Kim, Matthew G. Krebs, Rasha Cosman, Yoonha Choi, Sandhya Mandlekar, Mark T. Lin, Kenneth K. Yau, Julie Chang, Stephanie Royer-Joo, Neekesh V. Dharia, Jennifer L. Schutzman, Manish Patel
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT029.
https://doi.org/10.1158/1538-7445.AM2023-CT029
Published: 14 April 2023
View article titled, Abstract CT029: Phase Ib study of GDC-6036 in combination with cetuximab in patients with colorectal cancer (CRC) with <em>KRAS G12C</em> mutation
Journal Articles

Pharmacodynamics of Tamoxifen and Its 4-Hydroxy and N-Desmethyl Metabolites: Activation of Caspases and Induction of Apoptosis in Rat Mammary Tumors and in Human Breast Cancer Cell Lines

Sandhya Mandlekar, Vidya Hebbar, Konstantin Christov, A-N. Tony Kong
Journal: Cancer Research
Cancer Res (2000) 60 (23): 6601–6606.
Published: 01 December 2000
View article titled, Pharmacodynamics of Tamoxifen and Its 4-Hydroxy and <em>N</em>-Desmethyl Metabolites: Activation of Caspases and Induction of Apoptosis in Rat Mammary Tumors and in Human Breast Cancer Cell Lines
Open the PDF for Pharmacodynamics of Tamoxifen and Its 4-Hydroxy and <em>N</em>-Desmethyl Metabolites: Activation of Caspases and Induction of Apoptosis in Rat Mammary Tumors and in Human Breast Cancer Cell Lines in another window
Journal Articles

Activation of Caspase-3 and c-Jun NH2-terminal Kinase-1 Signaling Pathways in Tamoxifen-induced Apoptosis of Human Breast Cancer Cells

Sandhya Mandlekar, Rong Yu, Tse-Hua Tan, Ah-Ng Tony Kong
Journal: Cancer Research
Cancer Res (2000) 60 (21): 5995–6000.
Published: 01 November 2000
View article titled, Activation of Caspase-3 and c-Jun NH<sub>2</sub>-terminal Kinase-1 Signaling Pathways in Tamoxifen-induced Apoptosis of Human Breast Cancer Cells
Open the PDF for Activation of Caspase-3 and c-Jun NH<sub>2</sub>-terminal Kinase-1 Signaling Pathways in Tamoxifen-induced Apoptosis of Human Breast Cancer Cells in another window
Journal Articles

Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Androgen-independent Prostate Cancer Cells

Rong Yu, Sandhya Mandlekar, Steve Ruben, Jian Ni, A-N. Tony Kong
Journal: Cancer Research
Cancer Res (2000) 60 (9): 2384–2389.
Published: 01 May 2000
View article titled, Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Androgen-independent Prostate Cancer Cells
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Journal Articles

Induction of Apoptosis and Activation of Interleukin 1β-Converting Enzyme/Ced-3 Protease (Caspase-3) and c-Jun NH2-Terminal Kinase 1 by Benzo(a)pyrene

Wei Lei, Rong Yu, Sandhya Mandlekar, A-N. Tony Kong
Journal: Cancer Research
Cancer Res (1998) 58 (10): 2102–2106.
Published: 01 May 1998
View article titled, Induction of Apoptosis and Activation of Interleukin 1β-Converting Enzyme/Ced-3 Protease (Caspase-3) and c-Jun NH<sub>2</sub>-Terminal Kinase 1 by Benzo(<em>a</em>)pyrene
Open the PDF for Induction of Apoptosis and Activation of Interleukin 1β-Converting Enzyme/Ced-3 Protease (Caspase-3) and c-Jun NH<sub>2</sub>-Terminal Kinase 1 by Benzo(<em>a</em>)pyrene in another window
Journal Articles

Chemopreventive Isothiocyanates Induce Apoptosis and Caspase-3-like Protease Activity

Rong Yu, Sandhya Mandlekar, Kevin J. Harvey, David S. Ucker, A-N. Tony Kong
Journal: Cancer Research
Cancer Res (1998) 58 (3): 402–408.
Published: 01 February 1998
View article titled, Chemopreventive Isothiocyanates Induce Apoptosis and Caspase-3-like Protease Activity
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