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Samuele Gherardi
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Journal Articles

Abstract 2450: MYCN and TFAP4 promote neuroblastoma malignancy by cooperating in the regulation a subset of target genes involved in cancer cell growth and metastasis

Chengyuan Xue, Denise M. Yu, Samuele Gherardi, Jessica Koach, Giorgio Milazzo, Laura Gamble, Bing Liu, Amanda Russell, Tao Liu, Belamy B. Cheung, Glenn M. Marshall, Giovanni Perini, Michelle Haber, Murray D. Norris
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2450.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2450
Published: 15 July 2016
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Journal Articles

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Yuting Sun, Jessica L. Bell, Daniel Carter, Samuele Gherardi, Rebecca C. Poulos, Giorgio Milazzo, Jason W.H. Wong, Rima Al-Awar, Andrew E. Tee, Pei Y. Liu, Bing Liu, Bernard Atmadibrata, Matthew Wong, Toby Trahair, Quan Zhao, Jason M. Shohet, Ygal Haupt, Johannes H. Schulte, Peter J. Brown, Cheryl H. Arrowsmith, Masoud Vedadi, Karen L. MacKenzie, Stefan Hüttelmaier, Giovanni Perini, Glenn M. Marshall, Antony Braithwaite, Tao Liu
Journal: Cancer Research
Cancer Res (2015) 75 (23): 5143–5154.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-0423
Published: 30 November 2015
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Includes: Supplementary data
Journal Articles

Abstract 789: GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma

Murray D. Norris, Jamie I. Fletcher, Samuele Gherardi, Jayne Murray, Catherine Burkhart, Amanda Russell, Emanuele Valli, Andre Oberthuer, Lesley J. Ashton, Wendy B. London, Glenn M. Marshall, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 789.
DOI: https://doi.org/10.1158/1538-7445.AM2012-789
Published: 15 April 2012
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Journal Articles

N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma

Jamie I. Fletcher, Samuele Gherardi, Jayne Murray, Catherine A. Burkhart, Amanda Russell, Emanuele Valli, Janice Smith, André Oberthuer, Lesley J. Ashton, Wendy B. London, Glenn M. Marshall, Murray D. Norris, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2012) 72 (4): 845–853.
DOI: https://doi.org/10.1158/0008-5472.CAN-11-1885
Published: 14 February 2012
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Includes: Supplementary data
Journal Articles

Abstract 3027: SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein

Glenn M. Marshall, Pei Y. Liu, Samuele Gherardi, Christopher J. Scarlett, Antonio Bedalov, Ning Xu, Nunzio Iraci, Karen L. MacKenzie, Michelle Haber, Murray D. Norris, Andrew V. Biankin, Giovanni Perini, Tao Liu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3027.
DOI: https://doi.org/10.1158/1538-7445.AM2011-3027
Published: 15 April 2011
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Journal Articles

Abstract 954: ABCC/MRP multidrug transporters contribute to neuroblastoma biology, pathogenesis and clinical outcome, independently of any role in cytotoxic drug efflux

Murray D. Norris, Michelle J. Henderson, Antonio Porro, Marcia Munoz, Nunzio Iraci, Chengyuan Xue, Jayne Murray, Claudia Flemming, Jamie Fletcher, Samuele Gherardi, Alan Kwek, Amanda Russell, Wendy B. London, Allen B. Buxton, Lesley Ashton, Alan C. Sartorelli, Susan L. Cohn, Manfred Schwab, Glenn M. Marshall, Giovanni Perini, Michelle Haber
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 954.
DOI: https://doi.org/10.1158/1538-7445.AM2011-954
Published: 15 April 2011
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Journal Articles

A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at the TRKA and p75NTR Promoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF

Nunzio Iraci, Daniel Diolaiti, Antonella Papa, Antonio Porro, Emanuele Valli, Samuele Gherardi, Steffi Herold, Martin Eilers, Roberto Bernardoni, Giuliano Della Valle, Giovanni Perini
Journal: Cancer Research
Cancer Res (2011) 71 (2): 404–412.
DOI: https://doi.org/10.1158/0008-5472.CAN-10-2627
Published: 13 January 2011
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Includes: Supplementary data
Journal Articles

Abstract 4869: Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

Glenn M. Marshall, Samuele Gherardi, Ning Xu, Zillan Neiron, Toby Trahair, Christopher Scarlett, David K. Chang, Pei Y. Liu, Kacper Jankowski, Nunzio Iraci, Michelle Haber, Murray D. Norris, Fabio Stossi, Benita S. Katzenellenbogen, Andrew V. Biankin, Giovanni Perini, Tao Liu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4869.
DOI: https://doi.org/10.1158/1538-7445.AM10-4869
Published: 15 April 2010
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Journal Articles

p53 Is a Direct Transcriptional Target of MYCN in Neuroblastoma

Lindi Chen, Nunzio Iraci, Samuele Gherardi, Laura D. Gamble, Katrina M. Wood, Giovanni Perini, John Lunec, Deborah A. Tweddle
Journal: Cancer Research
Cancer Res (2010) 70 (4): 1377–1388.
DOI: https://doi.org/10.1158/0008-5472.CAN-09-2598
Published: 14 February 2010
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Includes: Supplementary data