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Samuel W. Brady
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Journal Articles

Abstract 3163: Ontology guided navigation of somatic variants, mutational signatures, gene expression and histology images for pediatric cancer

Alexander M. Gout, Stephanie Sandor, Delaram Rahbarinia, Jobin Sunny, James Madson, Lucian Vacaroiu, Wentao Yang, Ben Lansdell, Michael Macias, Samuel W. Brady, David Finkelstein, Victor Pastor, Kevin Benton, Andrew Frantz, Mark R. Wilkinson, Cynthia Cline, Brent A. Orr, Abbas Shirinifard, Elizabeth Stewart, Michael Rusch, Xin Zhou, Michael Dyer, David A. Wheeler, Clay McLeod, Jinghui Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3163.
https://doi.org/10.1158/1538-7445.AM2023-3163
Published: 04 April 2023
View article titled, Abstract 3163: Ontology guided navigation of somatic variants, mutational signatures, gene expression and histology images for pediatric cancer
Journal Articles

Abstract 633: Thiopurines and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse

Fan Yang, Samuel W. Brady, Huiying Sun, Chao Tang, Lijuan Du, Malwine Barz, Xiaotu Ma, Yao Chen, Houshun Fang, Xiaomeng Li, Pandurang Kolekar, Omkar Pathak, Jiaoyang Cai, Lixia Ding, Tianyi Wang, Arend von Stackelberg, Shuhong Shen, Caiwen Duan, Cornelia Eckert, Hongzhuan Chen, Yu Liu, Jeffery M. Klco, Hui Li, Benshang Li, Jinghui Zhang, Renate Kirschner-Schwabe, Bin-Bing S. Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 633.
https://doi.org/10.1158/1538-7445.AM2021-633
Published: 01 July 2021
View article titled, Abstract 633: Thiopurines and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse
Journal Articles

Abstract 3047: Spatial heterogeneity in diffuse intrinsic pontine gliomas treated with a PDGFR inhibitor

Sasi Arunachalam, Samuel W. Brady, Xiaotu Ma, Karol Szlachta, Heather Mulder, John Easton, Christopher L. Tinkle, Cynthia Wetmore, Suzanne J. Baker, Jinghui Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3047.
https://doi.org/10.1158/1538-7445.AM2021-3047
Published: 01 July 2021
View article titled, Abstract 3047: Spatial heterogeneity in diffuse intrinsic pontine gliomas treated with a PDGFR inhibitor
Journal Articles

Abstract 642: Genomes for Kids: Comprehensive DNA and RNA sequencing defining the scope of actionable mutations in pediatric cancer

David A. Wheeler, Scott Newman, Joy Nakitandwe, Chimene A. Kesserwan, Elizabeth M. Azzato, Michael C. Rusch, Sheila Shurtleff, Armita Bahrami, Brent Orr, Jeffery M. Klco, Dale J. Hedges, Kayla V. Hamilton, Scott G. Foy, Michael N. Edmonson, Andrew Thrasher, Jiali Gu, Lynn W. Harrison, Lu Wang, Roya Mostafavi, Manish Kubal, Jamie Maciaszek, Michael Clay, Annastasia Ouma, Antonina Silkov, Yanling Liu, Zhaojie Zhang, Yu Liu, Samuel W. Brady, Xin Zhou, Mark Wilkinson, Delaram Rahbarinia, Jay Knight, Jian Wang, Charles G. Mullighan, Rose B. McGee, Emily A. Quinn, Elsie L. Gerhardt, Leslie M. Taylor, Regina Nuccio, Jessica M. Valdez, Stacy J. Hines-Dowell, Alberto Pappo, Giles Robinson, Liza-Marie Johnson, Ching-Hon Pui, David W. Ellison, James R. Downing, Jinghui Zhang, Kim E. Nichols
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 642.
https://doi.org/10.1158/1538-7445.AM2021-642
Published: 01 July 2021
View article titled, Abstract 642: Genomes for Kids: Comprehensive DNA and RNA sequencing defining the scope of actionable mutations in pediatric cancer
Journal Articles

Abstract 2289: Empowering point-and-click genomic analysis with large pediatric genomic reference data on St. Jude Cloud

Andrew Thrasher, Michael Macias, Alexander M. Gout, Delaram Rahbarinia, Xin Zhou, Samuel W. Brady, Clay McLeod, Michael C. Rusch, Xiaolong Chen, Soheil Meshinchi, Michael A. Dyer, Suzanne J. Baker, Martine F. Roussel, Jinghui Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2289.
https://doi.org/10.1158/1538-7445.AM2021-2289
Published: 01 July 2021
View article titled, Abstract 2289: Empowering point-and-click genomic analysis with large pediatric genomic reference data on St. Jude Cloud
Journal Articles

Abstract 2872: Acquisition of drug resistance mutations during chemotherapy treatment in pediatric acute lymphoblastic leukemia

Benshang Li, Samuel W. Brady, Xiaotu Ma, Shuhong Shen, Yingchi Zhang, Yongjin Li, Yu Liu, Ningling Wang, Diane Flasch, Matthew Myers, Heather Mulder, Lixia Ding, Yanling Lu, Liqing Tian, Kohei Hagiwara, Ke Xu, Edgar Sioson, Tianyi Wang, Liu Yang, Jie Zhao, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Jiaoyang Cai, Ting-Nien Lin, Lijuan Du, Fan Yang, Michael Rusch, Michael Edmonson, John Easton, Xiaofan Zhu, Jingliao Zhang, Cheng Cheng, Benjamin Raphael, Jingyan Tang, James Downing, Bin-Bing Zhou, Ching-Hon Pui, Jun Yang, Jinghui Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2872.
https://doi.org/10.1158/1538-7445.AM2019-2872
Published: 01 July 2019
View article titled, Abstract 2872: Acquisition of drug resistance mutations during chemotherapy treatment in pediatric acute lymphoblastic leukemia
Journal Articles

Abstract 2910: Multi-sites rapid-autopsy data reveals aggressive metastatic colonization and metastasis phenotypes

Xiaomeng Huang, Yi Qiao, Samuel W. Brady, Adam Cohen, Andrea H. Bild, Gabor T. Marth
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2910.
https://doi.org/10.1158/1538-7445.AM2019-2910
Published: 01 July 2019
View article titled, Abstract 2910: Multi-sites rapid-autopsy data reveals aggressive metastatic colonization and metastasis phenotypes
Journal Articles

The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Jae Hyuk Yoo, Samuel W. Brady, Lehi Acosta-Alvarez, Aaron Rogers, Jingfu Peng, Lise K. Sorensen, Roger K. Wolff, Tara Mleynek, Donghan Shin, Coulson P. Rich, David A. Kircher, Andrea Bild, Shannon J. Odelberg, Dean Y. Li, Sheri L. Holmen, Allie H. Grossmann
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2892–2908.
https://doi.org/10.1158/0008-5472.CAN-18-3026
Published: 03 June 2019
View article titled, The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State
Open the PDF for The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State in another window
Includes: Supplementary data
Journal Articles

Abstract 2195: Temporal and spatial dynamics of metastatic colonization revealed by 26 rapid-autopsy tumor biopsies from a TNBC patient

Xiaomeng Huang, Yi Qiao, Samuel W. Brady, Adam Cohen, Andrea H. Bild, Gabor T. Marth
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2195.
https://doi.org/10.1158/1538-7445.AM2018-2195
Published: 01 July 2018
View article titled, Abstract 2195: Temporal and spatial dynamics of metastatic colonization revealed by 26 rapid-autopsy tumor biopsies from a TNBC patient
Journal Articles

Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Shalini Jain, Xiao Wang, Chia-Chi Chang, Catherine Ibarra-Drendall, Hai Wang, Qingling Zhang, Samuel W. Brady, Ping Li, Hong Zhao, Jessica Dobbs, Matt Kyrish, Tomasz S. Tkaczyk, Adrian Ambrose, Christopher Sistrunk, Banu K. Arun, Rebecca Richards-Kortum, Wei Jia, Victoria L. Seewaldt, Dihua Yu
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4863–4875.
https://doi.org/10.1158/0008-5472.CAN-14-2345
Published: 15 November 2015
View article titled, Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer
Open the PDF for Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB-221: PI3K-independent, Rheb-mediated mTOR activation promotes lapatinib resistance

Samuel W. Brady, Jian Zhang, Ming Horng Tsai, Dihua Yu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-221.
https://doi.org/10.1158/1538-7445.AM2014-LB-221
Published: 01 October 2014
View article titled, Abstract LB-221: PI3K-independent, Rheb-mediated mTOR activation promotes lapatinib resistance
Journal Articles

Abstract LB-215: Concomitant targeting of tumor cells and induction of T cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.

Qingfei Wang, Shau-Hsuan Li, Hai Wang, Yi Xiao, Ozgur Sahin, Samuel W. Brady, Ping Li, Elizabeth M. Jaffee, Gabriel N. Hortobagyi, Dihua Yu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-215.
https://doi.org/10.1158/1538-7445.AM2013-LB-215
Published: 15 April 2013
View article titled, Abstract LB-215: Concomitant targeting of tumor cells and induction of T cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.
Journal Articles

Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Qingfei Wang, Shau-Hsuan Li, Hai Wang, Yi Xiao, Ozgur Sahin, Samuel W. Brady, Ping Li, Hailiang Ge, Elizabeth M. Jaffee, William J. Muller, Gabriel N. Hortobagyi, Dihua Yu
Journal: Cancer Research
Cancer Res (2012) 72 (17): 4417–4428.
https://doi.org/10.1158/0008-5472.CAN-12-1339-T
Published: 30 August 2012
View article titled, Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer
Open the PDF for Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer in another window
Includes: Supplementary data