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Journal Articles

Abstract 2342: RO7119929, a TLR7 agonist prodrug, induces local inflammation of the tumor microenvironment (TME) by reprogramming myeloid cells in patients (pts) with advanced primary or metastatic liver cancers

Free
Carles Fabregat-Franco, Changhoon Yoo, Bruno Sangro, Camilla Qvortrup, Hyung-Don Kim, Teresa Macarulla, Mariano Ponz-Sarvisé, Chia-Chi Lin, Do-Youn Oh, Thomas Yau, Juliana Bessa, Petra C. Schwalie, Steffen Dettling, Ramona Schlenker, Natascha Riede, Elia Hall, Felix Lichtenegger, Nicole Kratochwil, Thomas Pöschinger, Zhiwen Jiang, Tianyi Jiang, Christina Godfried Sie, Audrey Yeo Te-Ying, Christina Schiff, Sabine Hoves, Michael Cannarile
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2342.
https://doi.org/10.1158/1538-7445.AM2023-2342
Published: 04 April 2023
View articletitled, Abstract 2342: RO7119929, a TLR7 agonist prodrug, induces local inflammation of the tumor microenvironment (TME) by reprogramming myeloid cells in patients (pts) with advanced primary or metastatic liver cancers
Journal Articles

Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages

Open Access
Aleksandar Murgaski, Máté Kiss, Helena Van Damme, Daliya Kancheva, Isaure Vanmeerbeek, Jiri Keirsse, Eva Hadadi, Jan Brughmans, Sana M. Arnouk, Ahmed E.I. Hamouda, Ayla Debraekeleer, Victor Bosteels, Yvon Elkrim, Louis Boon, Sabine Hoves, Niels Vandamme, Sofie Deschoemaeker, Sophie Janssens, Abhishek D. Garg, Greetje Vande Velde, Martina Schmittnaegel, Carola H. Ries, Damya Laoui
Journal: Cancer Research
Cancer Res (2022) 82 (20): 3785–3801.
https://doi.org/10.1158/0008-5472.CAN-22-0094
Published: 17 October 2022
View articletitled, Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages
Open the PDF for Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages in another window
Includes: Supplementary data
Journal Articles

Abstract 4084: Identifying characteristics of orthotopic HCC mouse models to predict response to immunotherapy

Free
Carina Hage, Sabine Hoves, Mailin Ashoff, Leanne Strauss, Mario Perro, Frank Herting, Fabian Kiessling, Thomas Pöschinger
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4084.
https://doi.org/10.1158/1538-7445.AM2018-4084
Published: 01 July 2018
View articletitled, Abstract 4084: Identifying characteristics of orthotopic HCC mouse models to predict response to immunotherapy
Journal Articles

Abstract PR04: Targeting tumor-asoociated macrophages with a novel anti-CSF1R antibody in cancer patients

Free
Michael Cannarile, Sabine Hoves, Ann-Marie Broeske, Joerg Benz, Katharina Wartha, Valeria Runza, Flora Rey-Giraud, Leon P. Pradel, Friedrich Feuerhake, Irina Klaman, Tobin Jones, Ute Jucknischke, Stefan Scheiblich, Ingo H. Gorr, Antje Walz, Keelara Abiraj, Philippe Cassier, Antonio Sica, Carlos Gomez-Roca, Christophe Le Tourneau, Jean-Pierre Delord, Antoine Italiano, Hyam Levitsky, Jean-Yves Blay, Dominik Ruettinger, Carola H. Ries
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): PR04.
https://doi.org/10.1158/1538-7445.CHTME14-PR04
Published: 12 January 2015
View articletitled, Abstract PR04: Targeting tumor-asoociated macrophages with a novel anti-CSF1R antibody in cancer patients
Journal Articles

Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer

Free
Jonathan Ellermeier, Jiwu Wei, Peter Duewell, Sabine Hoves, Mareike R. Stieg, Tina Adunka, Daniel Noerenberg, Hans-Joachim Anders, Doris Mayr, Hendrik Poeck, Gunther Hartmann, Stefan Endres, Max Schnurr
Journal: Cancer Research
Cancer Res (2013) 73 (6): 1709–1720.
https://doi.org/10.1158/0008-5472.CAN-11-3850
Published: 14 March 2013
View articletitled, Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer
Open the PDF for Therapeutic Efficacy of Bifunctional siRNA Combining TGF-β1 Silencing with RIG-I Activation in Pancreatic Cancer in another window
Includes: Supplementary data