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Abstract 7146: Unmasking host immune complexity: Single-cell transcriptomic analysis of circulating PBMCs in non-small cell lung cancer treated with immunotherapy based first line - I3LUNG study

Cancer Res (2025) 85 (8_Supplement_1): 7146.

https://doi.org/10.1158/1538-7445.AM2025-7146

Published: 21 April 2025

View articletitled, Abstract 7146: Unmasking host immune complexity: Single-cell transcriptomic analysis of circulating PBMCs in non-small cell lung cancer treated with immunotherapy based first line - I3LUNG study

Journal Articles

Abstract C014: Degradation of extracellular trap DNA sustains anti-tumor immune responses in breast cancer

Sabina Sangaletti, Paola Portararo, Laura Botti, Valeria Cancila, Claudio Tripodo, Mario P. Colombo, Claudia Chiodoni

Cancer Res (2024) 84 (22_Supplement): C014.

https://doi.org/10.1158/1538-7445.TUMBODY-C014

Published: 17 November 2024

View articletitled, Abstract C014: Degradation of extracellular trap DNA sustains anti-tumor immune responses in breast cancer

Journal Articles

Abstract B017: The double-edged sword of cystatin B in luminal-like and triple-negative breast cancers

Anna Zaccaria, Chiara Ratti, Laura Botti, Sabina Sangaletti, Mario P. Colombo, Claudia Chiodoni

Cancer Res (2024) 84 (22_Supplement): B017.

https://doi.org/10.1158/1538-7445.TUMBODY-B017

Published: 17 November 2024

View articletitled, Abstract B017: The double-edged sword of cystatin B in luminal-like and triple-negative breast cancers

Journal Articles

Abstract 1060: Circulating early myeloid derived suppressor cells as biomarkers for early detection of lung cancer

Orazio Fortunato, Barbara Bassani, Mara Lecchi, Paolo Verderio, Ugo Pastorino, Gabriella Sozzi, Mario Paolo Colombo, Sabina Sangaletti

Cancer Res (2024) 84 (6_Supplement): 1060.

https://doi.org/10.1158/1538-7445.AM2024-1060

Published: 22 March 2024

View articletitled, Abstract 1060: Circulating early myeloid derived suppressor cells as biomarkers for early detection of lung cancer

Journal Articles

Abstract 3637: Extracellular matrix drives high-grade breast cancer immune suppression down-modulating PD-1 on Treg cells via the IL-23/SATB1 axis

Giovanna Talarico, Mara Lecchi, Massimo Costanza, Claudia Chiodoni, Vera Cappelletti, Paolo Verderio, Massimo Di Nicola, Francesco Bertolini, Mario Paolo Colombo, Sabina Sangaletti

Cancer Res (2023) 83 (7_Supplement): 3637.

https://doi.org/10.1158/1538-7445.AM2023-3637

Published: 04 April 2023

View articletitled, Abstract 3637: Extracellular matrix drives high-grade breast cancer immune suppression down-modulating PD-1 on Treg cells via the IL-23/SATB1 axis

Journal Articles

Abstract 5506: Circulating immature neutrophils early detect hyperprogressive disease upon first-line PD-1/PD-L1 inhibitors in non-small cell lung cancer patients selecting best candidates for platinum-based chemotherapy and PD-1/PD-L1 inhibitors combinations

Cancer Res (2023) 83 (7_Supplement): 5506.

https://doi.org/10.1158/1538-7445.AM2023-5506

Published: 04 April 2023

View articletitled, Abstract 5506: Circulating immature neutrophils early detect hyperprogressive disease upon first-line PD-1/PD-L1 inhibitors in non-small cell lung cancer patients selecting best candidates for platinum-based chemotherapy and PD-1/PD-L1 inhibitors combinations

Journal Articles

ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Milena Perrone, Claudia Chiodoni, Mara Lecchi, Laura Botti, Barbara Bassani, Annamaria Piva, Elena Jachetti, Matteo Milani, Daniele Lecis, Elda Tagliabue, Paolo Verderio, Sabina Sangaletti, Mario P. Colombo

Cancer Res (2023) 83 (1): 117–129.

https://doi.org/10.1158/0008-5472.CAN-22-0651

Published: 04 January 2023

View articletitled, ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Includes: Supplementary data

Journal Articles

Abstract 2556: The protective role of mast cells against neuroendocrine prostate cancer depends on the release of cytokines mediated by intracellular osteopontin

Roberta Sulsenti, Barbara Frossi, Valeria Cancila, Claudia Enriquez, Renata Ferri, Sabina Sangaletti, Claudio Tripodo, Carlo Emilio Pucillo, Mario Paolo Colombo, Elena Jachetti

Cancer Res (2022) 82 (12_Supplement): 2556.

https://doi.org/10.1158/1538-7445.AM2022-2556

Published: 15 June 2022

View articletitled, Abstract 2556: The protective role of mast cells against neuroendocrine prostate cancer depends on the release of cytokines mediated by intracellular osteopontin

Journal Articles

Abstract 4480: Circulating and tumor associated neutrophil subtypes correlate with hyperprogressive disease (HPD) upon immunecheckpoint inhibitors (ICI) in advanced non-small cell lung cancer (aNSCLC) patients (pts) and in vivo models

Roberto Ferrara, Claudia Proto, Giuseppe Lo Russo, Diego Signorelli, Arsela Prelaj, Giulia Galli, Nicoletta Zilembo, Alessandro De Toma, Giuseppe Viscardi, Riccardo Lobefaro, Marta Brambilla, Monica Ganzinelli, Giuliano Molino, Giovanna Talarico, Marina Chiara Garassino, Mario Colombo, Sabina Sangaletti

Cancer Res (2020) 80 (16_Supplement): 4480.

https://doi.org/10.1158/1538-7445.AM2020-4480

Published: 15 August 2020

View articletitled, Abstract 4480: Circulating and tumor associated neutrophil subtypes correlate with hyperprogressive disease (HPD) upon immunecheckpoint inhibitors (ICI) in advanced non-small cell lung cancer (aNSCLC) patients (pts) and in vivo models

Journal Articles

Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs

Cancer Res (2020) 80 (13): 2874–2888.

https://doi.org/10.1158/0008-5472.CAN-19-2843

Published: 02 July 2020

View articletitled, Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs

Includes: Supplementary data

Journal Articles

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

Claudia Chiodoni, Valeria Cancila, Tiziana A. Renzi, Milena Perrone, Andrea M. Tomirotti, Sabina Sangaletti, Laura Botti, Matteo Dugo, Matteo Milani, Lucia Bongiovanni, Maurizio Marrale, Claudio Tripodo, Mario P. Colombo

Cancer Res (2020) 80 (3): 484–498.

https://doi.org/10.1158/0008-5472.CAN-19-1425

Published: 03 February 2020

View articletitled, Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

Includes: Supplementary data

Journal Articles

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

Cristina Travelli, Francesca Maria Consonni, Sabina Sangaletti, Mariangela Storto, Sara Morlacchi, Ambra A. Grolla, Ubaldina Galli, Gian Cesare Tron, Paola Portararo, Lorenza Rimassa, Tiziana Pressiani, Massimiliano Mazzone, Rosalinda Trovato, Stefano Ugel, Vincenzo Bronte, Claudio Tripodo, Mario P. Colombo, Armando A. Genazzani, Antonio Sica

Cancer Res (2019) 79 (8): 1938–1951.

https://doi.org/10.1158/0008-5472.CAN-18-1544

Published: 15 April 2019

View articletitled, Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

Includes: Supplementary data

Journal Articles

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Claudio Tripodo, Alessia Burocchi, Pier Paolo Piccaluga, Claudia Chiodoni, Paola Portararo, Barbara Cappetti, Laura Botti, Alessandro Gulino, Alessandro Isidori, Arcangelo Liso, Giuseppe Visani, Maria Paola Martelli, Brunangelo Falini, Pier Paolo Pandolfi, Mario P. Colombo, Sabina Sangaletti

Cancer Res (2017) 77 (13): 3685–3699.

https://doi.org/10.1158/0008-5472.CAN-17-1098

Published: 02 July 2017

View articletitled, Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Includes: Supplementary data

Journal Articles

Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth

Alice Rigoni, Lucia Bongiovanni, Alessia Burocchi, Sabina Sangaletti, Luca Danelli, Carla Guarnotta, Amy Lewis, Aroldo Rizzo, Andrew R. Silver, Claudio Tripodo, Mario P. Colombo

Cancer Res (2015) 75 (18): 3760–3770.

https://doi.org/10.1158/0008-5472.CAN-14-3767

Published: 14 September 2015

View articletitled, Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth

Includes: Supplementary data

Journal Articles

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

Caterina Vitali, Claudia Bassani, Claudia Chiodoni, Elisa Fellini, Carla Guarnotta, Silvia Miotti, Sabina Sangaletti, Fabio Fuligni, Loris De Cecco, Pier P. Piccaluga, Mario P. Colombo, Claudio Tripodo

Cancer Res (2015) 75 (11): 2387–2399.

https://doi.org/10.1158/0008-5472.CAN-14-3625

Published: 31 May 2015

View articletitled, SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

Includes: Supplementary data

Journal Articles

Osteopontin Shapes Immunosuppression in the Metastatic Niche

Sabina Sangaletti, Claudio Tripodo, Sara Sandri, Ilaria Torselli, Caterina Vitali, Chiara Ratti, Laura Botti, Alessia Burocchi, Rossana Porcasi, Andrea Tomirotti, Mario P. Colombo, Claudia Chiodoni

Cancer Res (2014) 74 (17): 4706–4719.

https://doi.org/10.1158/0008-5472.CAN-13-3334

Published: 01 September 2014

View articletitled, Osteopontin Shapes Immunosuppression in the Metastatic Niche

Includes: Supplementary data

Journal Articles

Abstract 2877: Dual role of mast cells in prostate tumors.

Mario P. Colombo, Paola Pittoni, Sabina Sangaletti, Claudio Tripodo

Cancer Res (2013) 73 (8_Supplement): 2877.

https://doi.org/10.1158/1538-7445.AM2013-2877

Published: 15 April 2013

View articletitled, Abstract 2877: Dual role of mast cells in prostate tumors.

Journal Articles

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

Melody A. Swartz, Noriho Iida, Edward W. Roberts, Sabina Sangaletti, Melissa H. Wong, Fiona E. Yull, Lisa M. Coussens, Yves A. DeClerck

Cancer Res (2012) 72 (10): 2473–2480.

https://doi.org/10.1158/0008-5472.CAN-12-0122

Published: 14 May 2012

View articletitled, Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

Journal Articles

Mast Cell Targeting Hampers Prostate Adenocarcinoma Development but Promotes the Occurrence of Highly Malignant Neuroendocrine Cancers

Paola Pittoni, Claudio Tripodo, Silvia Piconese, Giorgio Mauri, Mariella Parenza, Alice Rigoni, Sabina Sangaletti, Mario P. Colombo

Cancer Res (2011) 71 (18): 5987–5997.

https://doi.org/10.1158/0008-5472.CAN-11-1637

Published: 13 September 2011

View articletitled, Mast Cell Targeting Hampers Prostate Adenocarcinoma Development but Promotes the Occurrence of Highly Malignant Neuroendocrine Cancers

Includes: Supplementary data

Journal Articles

Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis

Sabina Sangaletti, Claudio Tripodo, Chiara Ratti, Silvia Piconese, Rossana Porcasi, Rosalba Salcedo, Giorgio Trinchieri, Mario P. Colombo, Claudia Chiodoni

Cancer Res (2010) 70 (20): 7764–7775.

https://doi.org/10.1158/0008-5472.CAN-10-0471

Published: 13 October 2010

View articletitled, Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis

Includes: Supplementary data

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Abstract 7146: Unmasking host immune complexity: Single-cell transcriptomic analysis of circulating PBMCs in non-small cell lung cancer treated with immunotherapy based first line - I3LUNG study

Abstract C014: Degradation of extracellular trap DNA sustains anti-tumor immune responses in breast cancer

Abstract B017: The double-edged sword of cystatin B in luminal-like and triple-negative breast cancers

Abstract 1060: Circulating early myeloid derived suppressor cells as biomarkers for early detection of lung cancer

Abstract 3637: Extracellular matrix drives high-grade breast cancer immune suppression down-modulating PD-1 on Treg cells via the IL-23/SATB1 axis

Abstract 5506: Circulating immature neutrophils early detect hyperprogressive disease upon first-line PD-1/PD-L1 inhibitors in non-small cell lung cancer patients selecting best candidates for platinum-based chemotherapy and PD-1/PD-L1 inhibitors combinations

ATF3 Reprograms the Bone Marrow Niche in Response to Early Breast Cancer Transformation

Abstract 2556: The protective role of mast cells against neuroendocrine prostate cancer depends on the release of cytokines mediated by intracellular osteopontin

Abstract 4480: Circulating and tumor associated neutrophil subtypes correlate with hyperprogressive disease (HPD) upon immunecheckpoint inhibitors (ICI) in advanced non-small cell lung cancer (aNSCLC) patients (pts) and in vivo models

Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs

Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to Early Breast Cancer in Association with Deregulated Circulating microRNAs

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth

SOCS2 Controls Proliferation and Stemness of Hematopoietic Cells under Stress Conditions and Its Deregulation Marks Unfavorable Acute Leukemias

Osteopontin Shapes Immunosuppression in the Metastatic Niche

Abstract 2877: Dual role of mast cells in prostate tumors.

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

Mast Cell Targeting Hampers Prostate Adenocarcinoma Development but Promotes the Occurrence of Highly Malignant Neuroendocrine Cancers

Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis

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