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Sébastien Benzekry
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Journal Articles

Abstract LB120: Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial

Laurent Greillier, Florence Monville, Vanina Leca, Frédéric Vely, Stephane Garcia, Joseph Ciccolini, Florence Sabatier, Gilbert Ferrani, Nawel Boudai, Lamia Ghezali, Marcellin Landri, Clémence Marin, Mourad Hamimed, Laurent Arnaud, Melanie Karlsen, Kevin Atsou, Sivan Bokobza, Pauline Fleury, Arnaud Boyer, Clarisse Audigier-Valette, Stéphanie Martinez, Hervé Pegliasco, Patrice Ray, Lionel Falchero, Antoine Serre, Nicolas Cloarec, Louisiane Lebas, Stephane Hominal, Patricia Barre, Sarah Zahi, Ahmed Frikha, Pierre Bory, Maryannick Le Ray, Lilian Laborde, Virginie Martin, Richard Malkoun, Marie Roumieux, Julien Mazieres, Maurice Perol, Eric Vivier, Sebastien Benzekry, Jacques Fieschi, Fabrice Barlesi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB120.
https://doi.org/10.1158/1538-7445.AM2022-LB120
Published: 15 June 2022
View article titled, Abstract LB120: Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial
Journal Articles

Abstract 2737: A mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine clinical features

Célestin Bigarré, Pascal Finetti, François Bertucci, Xavier Muracciole, Sébastien Benzekry
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2737.
https://doi.org/10.1158/1538-7445.AM2022-2737
Published: 15 June 2022
View article titled, Abstract 2737: A mechanistic model for prediction of metastatic relapse in early-stage breast cancer using routine clinical features
Journal Articles

Abstract 3195: Hijacked senescence secretomes as 'immune primers' of antiangiogenic TKI efficacy

Melissa Dolan, Yuhao Shi, James W. Hill, Michalis Mastri, Cristina Vaghi, Joseph Barbi, Sebastien Benzekry, John M. Ebos
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3195.
https://doi.org/10.1158/1538-7445.AM2021-3195
Published: 01 July 2021
View article titled, Abstract 3195: Hijacked senescence secretomes as 'immune primers' of antiangiogenic TKI efficacy
Journal Articles

Abstract 6244: Turning poorly vascularized tumors into highly vascularized tumors with nanoparticles: Proof of concept and pharmacometric analysis

Guillaume Sicard, Anne Rodallec, Florian Correard, Cristina Vaghi, Clair Poignard, Joseph Ciccolini, Sébastien Benzekry, Arnauld Sergé, Raphaelle Fanciullino
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6244.
https://doi.org/10.1158/1538-7445.AM2020-6244
Published: 15 August 2020
View article titled, Abstract 6244: Turning poorly vascularized tumors into highly vascularized tumors with nanoparticles: Proof of concept and pharmacometric analysis
Journal Articles

Abstract 5493: Mathematical modeling of antibody nanoconjugates transport quantifies the impact of the tumor microenvironment on drug penetration

Cristina Vaghi, Anne Rodallec, Guillaume Sicard, Florian Correard, Raphaelle Fanciullino, Joseph Ciccolini, Clair Poignard, Sebastien Benzekry
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5493.
https://doi.org/10.1158/1538-7445.AM2020-5493
Published: 15 August 2020
View article titled, Abstract 5493: Mathematical modeling of antibody nanoconjugates transport quantifies the impact of the tumor microenvironment on drug penetration
Journal Articles

Abstract 4264: Mathematical modeling of differential effects of sunitinib on primary tumor and metastatic growth

Chiara Nicolò, Michalis Mastri, Amanda Tracz, John M. Ebos, Sébastien Benzekry
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4264.
https://doi.org/10.1158/1538-7445.AM2018-4264
Published: 01 July 2018
View article titled, Abstract 4264: Mathematical modeling of differential effects of sunitinib on primary tumor and metastatic growth
Journal Articles

Mathematical Modeling of Tumor–Tumor Distant Interactions Supports a Systemic Control of Tumor Growth

Sebastien Benzekry, Clare Lamont, Dominique Barbolosi, Lynn Hlatky, Philip Hahnfeldt
Journal: Cancer Research
Cancer Res (2017) 77 (18): 5183–5193.
https://doi.org/10.1158/0008-5472.CAN-17-0564
Published: 14 September 2017
View article titled, Mathematical Modeling of Tumor–Tumor Distant Interactions Supports a Systemic Control of Tumor Growth
Open the PDF for Mathematical Modeling of Tumor–Tumor Distant Interactions Supports a Systemic Control of Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 4529: Optimization of the sequence for the administration of bevacizumab in combination with pemetrexed and cisplatin in NSCLC : a pharmacology based in vivo study

arnaud boyer, diane-charlotte imbs, raouf el cheikh, celine mascaux, fabrice barlesi, dominique barbolosi, sebastien benzekry, joseph ciccolini
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4529.
https://doi.org/10.1158/1538-7445.AM2017-4529
Published: 01 July 2017
View article titled, Abstract 4529: Optimization of the sequence for the administration of bevacizumab in combination with pemetrexed and cisplatin in NSCLC : a pharmacology based in vivo study
Journal Articles

Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy

Raphael Serre, Sebastien Benzekry, Laetitia Padovani, Christophe Meille, Nicolas André, Joseph Ciccolini, Fabrice Barlesi, Xavier Muracciole, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2016) 76 (17): 4931–4940.
https://doi.org/10.1158/0008-5472.CAN-15-3567
Published: 31 August 2016
View article titled, Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy
Open the PDF for Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 2099: Model-riven optimization of anti-angiogenics combined with chemotherapy: application to bevacizumab + pemetrexed/cisplatin doublet in NSCLC-bearing mice

Joseph Ciccolini, Sebastien Benzekry, Sarah Giacometti, Fabrice Barlesi, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2099.
https://doi.org/10.1158/1538-7445.AM2016-2099
Published: 15 July 2016
View article titled, Abstract 2099: Model-riven optimization of anti-angiogenics combined with chemotherapy: application to bevacizumab + pemetrexed/cisplatin doublet in NSCLC-bearing mice
Journal Articles

Abstract 2704: Radiotherapy and immunotherapy in cancer: A mathematical model

Raphael Serre, Xavier Muracciole, Joseph Ciccolini, Sebastien Benzekry, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2704.
https://doi.org/10.1158/1538-7445.AM2016-2704
Published: 15 July 2016
View article titled, Abstract 2704: Radiotherapy and immunotherapy in cancer: A mathematical model
Journal Articles

Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach

Sebastien Benzekry, Amanda Tracz, Michalis Mastri, Ryan Corbelli, Dominique Barbolosi, John M.L. Ebos
Journal: Cancer Research
Cancer Res (2016) 76 (3): 535–547.
https://doi.org/10.1158/0008-5472.CAN-15-1389
Published: 31 January 2016
View article titled, Modeling Spontaneous Metastasis following Surgery: An <em>In Vivo-In Silico</em> Approach
Open the PDF for Modeling Spontaneous Metastasis following Surgery: An <em>In Vivo-In Silico</em> Approach in another window
Includes: Multimedia, Supplementary data
Journal Articles

Host Age Is a Systemic Regulator of Gene Expression Impacting Cancer Progression

Afshin Beheshti, Sébastien Benzekry, J. Tyson McDonald, Lili Ma, Michael Peluso, Philip Hahnfeldt, Lynn Hlatky
Journal: Cancer Research
Cancer Res (2015) 75 (6): 1134–1143.
https://doi.org/10.1158/0008-5472.CAN-14-1053
Published: 12 March 2015
View article titled, Host Age Is a Systemic Regulator of Gene Expression Impacting Cancer Progression
Open the PDF for Host Age Is a Systemic Regulator of Gene Expression Impacting Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 3677: Model-based optimization of combined antiangiogenic + cytotoxics modalities: application to the bevacizumab-paclitaxel association in breast cancer models

Severine Mollard, Sebastien Benzekry, Sarah Giacometti, Christian Faivre, Florence Hubert, Joseph Ciccolini, Dominique Barbolosi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3677.
https://doi.org/10.1158/1538-7445.AM2014-3677
Published: 01 October 2014
View article titled, Abstract 3677: Model-based optimization of combined antiangiogenic + cytotoxics modalities: application to the bevacizumab-paclitaxel association in breast cancer models