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Ryan J. Sullivan
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Journal Articles

Abstract CT160: BVD-523FB (Ulixertinib) in Patients with Tumors with BRAF Fusions, or with Non-V600E, Non-V600K BRAF Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Sub-protocol EAY131-Z1L

Vivek Subbiah, Fengmin Fengmin, Ragini Kudchadkar, Ryan J. Sullivan, Edith P. Mitchell, John J. Wright, Helen X. Chen, Robert J. Gray, Xin Victoria Wang, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Tilak K. Sundaresan, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O'Dwyer, Alice P. Chen, Keith T. Flaherty
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT160.
DOI: https://doi.org/10.1158/1538-7445.AM2022-CT160
Published: 15 June 2022
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Abstract CT002: Phase 3 randomized trial comparing tebentafusp with investigator's choice in first line metastatic uveal melanoma

Sophie Piperno-Neumann, Jessica C. Hassel, Piotr Rutkowski, Jean-Francois Baurain, Marcus O. Butler, Max Schlaak, Ryan J. Sullivan, Sebastian Ochsenreither, Reinhard Dummer, John M. Kirkwood, Anthony M. Joshua, Joseph J. Sacco, Alexander N. Shoushtari, Marlana Orloff, Richard D. Carvajal, Omid Hamid, Shaad E. Abdullah, Chris Holland, Howard Goodall, Paul Nathan
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT002.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT002
Published: 01 July 2021
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Journal Articles

Abstract CT108: A first-in-human, Phase 1 study of ASTX029, a dual-mechanism inhibitor of ERK1/2, in relapsed/refractory solid tumors

Patricia LoRusso, Drew Rasco, Geoffrey Shapiro, Filip Janku, Alain Mita, Nilofer Azad, Marcia Toguchi, Chris Hindley, Shannon Bradley, Danna Chan, Harold Keer, Kim-Hien Dao, Ryan J. Sullivan, Alexander Spira
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT108.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT108
Published: 01 July 2021
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Journal Articles

Abstract LB-260: The use of blood-based protein biomarkers to uncover determinants of immunotherapy response in melanoma

Arnav Mehta, Marijana Rucevic, Emmett Sprecher, Lina H. Rosenberg, David Lieb, Gyulnara Kasumova, Michelle S. Kim, Xue Bai, Dennie T. Frederick, Keith Flaherty, Ryan J. Sullivan, Nir Hacohen, Genevieve Boland
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-260.
DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-260
Published: 15 August 2020
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Journal Articles

Abstract 6670: Combined signals from tumor and immune cells predict outcomes of checkpoint inhibition in melanoma

Samuel S. Freeman, Moshe Sade-Feldman, Jaegil Kim, Chip Stewart, Arvind Ravi, Monica Arniella, Keren Yizhak, Ignaty Leshchiner, Liudmila Elagina, Oliver Spiro, Dimitri Livitz, Daniel Rosebrock, François Aguet, Jian Carrot-Zhang, Anna Gonye, Gavin Ha, Ziao Lin, Jonathan H. Chen, Dennie T. Frederick, Michal Barzily-Rokni, Marc R. Hammond, Hans Vitzthum, Shauna M. Blackmon, Yunxin J. Jiao, Donald P. Lawrence, Lyn M. Duncan, Anat Stemmer-Rachamimov, Jennifer A. Wargo, Keith T. Flaherty, Genevieve M. Boland, Ryan J. Sullivan, Matthew Meyerson, Gad Getz, Nir Hacohen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6670.
DOI: https://doi.org/10.1158/1538-7445.AM2020-6670
Published: 15 August 2020
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Journal Articles

Abstract 6073: The lipogenic regulator SREBP induces Transferrin in circulating melanoma cells, suppressing their susceptibility to ferroptosis

Xin Hong, Whijae Roh, Ryan J. Sullivan, Keith H. Wong, Ben S. Wittner, HongShan Guo, Taronish D. Dubash, Moshe Sade-Feldman, Ben K. Wesley, Genevieve M. Boland, Dieuwke L. Marvin, Todd Bonesteel, Chenyue Lu, Elad Horwitz, François Aguet, Samuel S. Freeman, Katherine Calhoun, Michelle K. Jewett, Linda T. Nieman, Nir Hacohen, Anders M. Näär, David T. Ting, Mehmet Toner, Shannon L. Stott, Gad Getz, Shyamala Maheswaran, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6073.
DOI: https://doi.org/10.1158/1538-7445.AM2020-6073
Published: 15 August 2020
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Journal Articles

Abstract 4533: Plasma and exosome proteomic profiling for prediction of immunotherapy response and toxicity

Arnav Mehta, Gyulnara Kasumova, Alvin Shi, Marijana Rucevic, Markus Sallman-Almen, Lina Hultin Rosenberg, Emmett Sprecher, Jacqueline Ohmura, Michelle Kim, David Lieb, Xue Bai, Dennie T. Frederick, Manolis Kellis, Ryan J. Sullivan, Keith T. Flaherty, Nir Hacohen, Genevieve M. Boland
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4533.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4533
Published: 01 July 2019
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Journal Articles

Abstract 3013: Acquired resistance to immune checkpoint inhibition by melanoma phenotypic transformation

Arnav Mehta, David Liu, Alvin Shi, Dennie T. Frederick, Li-Lun Ho, Ana B. Larque, Benchun Miao, Rumya S. Raghavan, Tatyana Sharova, John H. Shin, Nicola Rinaldi, Ivan A. Chebib, Manolis Kellis, Eliezer Van Allen, Nir Hacohen, Keith T. Flaherty, Genevieve M. Boland, Ryan J. Sullivan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3013.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3013
Published: 01 July 2019
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Journal Articles

Abstract CT072: Efficacy and safety of entinostat (ENT) and pembrolizumab (PEMBRO) in patients with melanoma previously treated with anti-PD1 therapy

Ryan J. Sullivan, Stergios J. Moschos, Melissa L. Johnson, Mateusz Opyrchal, Peter Ordentlich, Susan Brouwer, Serap Sankoh, Michael L. Meyers, Sanjiv S. Agarwala
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT072.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT072
Published: 01 July 2019
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Journal Articles

Abstract LB-144: Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy

Xin Hong, Ryan J. Sullivan, Mark Kalinich, Tanya Kwan, Shiwei Pan, Joseph A. LiCausi, John D. Milner, Linda T. Nieman, Ben S. Wittner, Uyen Ho, Tianqi Chen, Ravi Kapur, Don Lawrence, Keith T. Flaherty, Lecia V. Sequist, Sridhar Ramaswamy, David T. Miyamoto, Michael Lawrence, Anita Giobbie-Hurder, Mehmet Toner, Kurt J. Isselbacher, Shyamala Maheswaran, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-144.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-144
Published: 01 July 2018
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Journal Articles

Abstract CT129: Phase 2 study of cabozantinib in patients with non-breast, non-prostate cancer with bone metastasis

Edwin Choy, Gregory M. Cote, M. Dror Michaelson, Lori Wirth, Justin F. Gainor, Lecia V. Sequist, Ryan J. Sullivan, Panagiotis M. Fidias, Alice Shaw, Rebecca S. Heist
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT129.
DOI: https://doi.org/10.1158/1538-7445.AM2017-CT129
Published: 01 July 2017
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Journal Articles

Abstract CT003: Activity of the ERK1/2 inhibitor ulixertinib (BVD-523) in patients with BRAF and NRAS mutant melanoma

Ryan J. Sullivan, Filip Janku, Bob T. Li, Deborah Wong, Jeffrey Sosman, Vicki Keedy, Elizabeth Buchbinder, Anthony Tolcher, Anna Varghese, David M. Hyman, Keith T. Flaherty, Antoni Ribas, Richard Carvajal, Andrea Wang-Gillam, Harriet Kluger, Manish Patel, Peter Langecker, Mary Varterasian, Dean Welsch, Jeffrey Infante
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT003.
DOI: https://doi.org/10.1158/1538-7445.AM2017-CT003
Published: 01 July 2017
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Journal Articles

Abstract 2679: Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma

Neel M. Fofaria, Dennie T. Frederick, Ryan J. Sullivan, Keith T. Flaherty, Sanjay K. Srivastava
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2679.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2679
Published: 01 August 2015
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Journal Articles

Abstract 2942: NRAS mutation as a predictor of response to immune-based therapies in patients with metastatic melanoma

Wade T. Iams, Douglas B. Johnson, Marisa Flavin, Katherine Panageas, Gregory D. Ayers, Zhiguo Zhao, Anthony John Iafrate, Ryan J. Sullivan, Richard D. Carvajal, Jeffrey A. Sosman, Christine M. Lovly
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2942.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2942
Published: 01 October 2014
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Journal Articles

Abstract 4832: Isolation and molecular characterization of circulating melanoma cells

Xi Luo, Devarati Mitra, Ryan J. Sullivan, Ben S. Wittner, Anya M. Kimura, Shiwei Pan, Mai P. Hoang, Brian W. Brannigan, Donald P. Lawrence, Keith T. Flaherty, Lecia V. Sequist, Shannon L. Stott, David T. Ting, Sridhar Ramaswamy, Mehmet Toner, David E. Fisher, Shyamala Maheswaran, Daniel A. Haber
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4832.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4832
Published: 01 October 2014
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Journal Articles

Abstract 1724: BRAF inhibition is enhanced by BH3-mimetic through BIM induction.

Dennie T. Frederick, Roberto A. Salas Fragomeni, Taylor Hoff, Zachary A. Cooper, James W. Mier, Jennifer A. Wargo, Ryan J. Sullivan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1724.
DOI: https://doi.org/10.1158/1538-7445.AM2013-1724
Published: 15 April 2013
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Journal Articles

Abstract 2338: BRAF inhibition is associated with increased clonality of tumor infiltrating lymphocytes.

Zachary A. Cooper, Dennie T. Frederick, Ryan J. Sullivan, Donald P. Lawrence, Adriano Piris, Keith T. Flaherty, David A. Fisher, Jennifer A. Wargo
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2338.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2338
Published: 15 April 2013
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