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Journal Articles

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC

Paul B.M. Essers, Martijn van der Heijden, Caroline V.M. Verhagen, Emily M. Ploeg, Reinout H. de Roest, C. René Leemans, Ruud H. Brakenhoff, Michiel W.M. van den Brekel, Harry Bartelink, Marcel Verheij, Conchita Vens

Cancer Res (2019) 79 (21): 5597–5611.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-3388

Published: 01 November 2019

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Includes: Supplementary data

Journal Articles

Abstract 4638: Targeted therapy of precancerous fields in the mucosal linings of the head and neck

D Vicky de Boer, Sanne R. Martens-de Kemp, Marijke Buijze, Marijke Stigter-van Walsum, Elisabeth Bloemena, C René Leemans, Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff

Cancer Res (2016) 76 (14_Supplement): 4638.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4638

Published: 15 July 2016

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Journal Articles

Abstract 4637: Chk1 inhibition: a promising targeted treatment for head and neck squamous cell carcinoma

Anne M. van Harten, Marijke Stigter-van Walsum, Marijke Buijze, Boudewijn Jm Braakhuis, Ruud H. Brakenhoff

Cancer Res (2016) 76 (14_Supplement): 4637.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4637

Published: 15 July 2016

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Journal Articles

Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer

Chantal Stoepker, Najim Ameziane, Petra van der Lelij, Irsan E. Kooi, Anneke B. Oostra, Martin A. Rooimans, Saskia E. van Mil, Arjen Brink, Ralf Dietrich, Jesper A. Balk, Bauke Ylstra, Hans Joenje, Stephan M. Feller, Ruud H. Brakenhoff

Cancer Res (2015) 75 (17): 3543–3553.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-0528

Published: 31 August 2015

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Includes: Supplementary data

Journal Articles

Abstract 2488: Novel candidate protein biomarkers for cisplatin response prediction in non-small cell lung cancer.

Tieneke B M Schaaij-Visser, Remco Nagel, Inge de Reus, Sander R. Piersma, Thang V. Pham, Egbert F. Smit, Frederik B. Thunnissen, Ruud H. Brakenhoff, Anton Berns, Connie R. Jimenez

Cancer Res (2013) 73 (8_Supplement): 2488.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2488

Published: 15 April 2013

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Journal Articles

Abstract 338: Truncating TP53 mutations have prognostic significance in head and neck squamous cell carcinoma

Marlon van der Plas, Ruud H. Brakenhoff, Dirk J. Kuik, Marijke Buijze, Elisabeth Bloemena, Peter Jf Snijders, C. René Leemans, Boudewijn Jm Braakhuis

Cancer Res (2011) 71 (8_Supplement): 338.

DOI: https://doi.org/10.1158/1538-7445.AM2011-338

Published: 15 April 2011

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Journal Articles

Abstract 4122: Multi-center validation of a lymph node metastasis gene-expression signature for head and neck squamous cell carcinomas

Ernst-Jan M. Speel, Frank K.J. Leusink, Sander R. van Hooff, J Alain Kummer, Paul J. van Diest, Ronald Koole, Paul Roepman, Michiel W.M. van den Brekel, Thijs A. Merkx, Jeroen C. Jansen, Ed M.D. Schuuring, Ruud H. Brakenhoff, Robert J. Baatenburg de Jong, Piet J. Slootweg, Frank C.P. Holstege, Robert P. Takes

Cancer Res (2011) 71 (8_Supplement): 4122.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4122

Published: 15 April 2011

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Journal Articles

Abstract 4823: Single cell analysis of head and neck squamous cell carcinoma cells isolated from primary tumors and matched metastases

Karl C. Sproll, Bianca Behrens, Andrea Hollinger, Stephan E. Baldus, Norbert R. Kübler, Wolfram T. Knoefel, Ruud H. Brakenhoff, Nikolas H. Stoecklein

Cancer Res (2011) 71 (8_Supplement): 4823.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4823

Published: 15 April 2011

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Journal Articles

Abstract 5100: Secretome proteomics to identify indicators for lung cancer treatment response prediction and monitoring

Tieneke B.M Schaaij-Visser, Natalie Proost, Remco Nagel, Sander R. Piersma, Thang V. Pham, Ruud H. Brakenhoff, Anton Berns, Connie R. Jimenez

Cancer Res (2011) 71 (8_Supplement): 5100.

DOI: https://doi.org/10.1158/1538-7445.AM2011-5100

Published: 15 April 2011

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Journal Articles

Abstract 1750: Identification of genes involved in chemoradiation response of head and neck cancer by functional genetic screens

Sanne R. Martens-de Kemp, Arjen Brink, Ida H. van der Meulen, Dirk J. Kuik, Renee Menezes, Boudewijn JM Braakhuis, Victor W. van Beusechem, Ruud H. Brakenhoff

Cancer Res (2011) 71 (8_Supplement): 1750.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1750

Published: 15 April 2011

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Journal Articles

Human Lymphoblastoid Proteome Analysis Reveals a Role for the Inhibitor of Acetyltransferases Complex in DNA Double-Strand Break Response

Eef H.C. Dirksen, Jacqueline Cloos, Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff, Albert J.R. Heck, Monique Slijper

Cancer Res (2006) 66 (3): 1473–1480.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-2129

Published: 01 February 2006

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Includes: Supplementary data

Journal Articles

Different genome wide DNA copy number alterations in head and neck squamous cell carcinomas with or without transcriptionally active human papillomavirus.

Serge J. Smeets, Boudewijn J. Braakhuis, Saman Abbas, Peter J. Snijders, Bauke Ylstra, C René Leemans, Ruud H. Brakenhoff

Cancer Res (2005) 65 (9_Supplement): 85.

Published: 01 May 2005

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Journal Articles

Multiplex Ligation-dependent Probe Amplification (MLPA), a novel genetic test for non-invasive detection of oral preneoplastic lesions

Jantien F. Bremmer, C. René Leemans, Isäac Van der Waal, Jan P. Schouten, Ruud H. Brakenhoff, Boudewijn J. M. Braakhuis

Cancer Res (2005) 65 (9_Supplement): 373.

Published: 01 May 2005

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Journal Articles

Generation and Molecular Characterization of Head and Neck Squamous Cell Lines of Fanconi Anemia Patients

Hester J.T. van Zeeburg, Peter J.F. Snijders, Gerard Pals, Mario A.J.A. Hermsen, Martin A. Rooimans, Grover Bagby, Jean Soulier, Eliane Gluckman, Johan Wennerberg, C. René Leemans, Hans Joenje, Ruud H. Brakenhoff

Cancer Res (2005) 65 (4): 1271–1276.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-3665

Published: 25 February 2005

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Journal Articles

Correspondence re: M. P. Rosin et al ., 3p14 and 9p21 Loss Is a Simple Tool for Predicting Second Oral Malignancy at Previously Treated Oral Cancer Sites. Cancer Res., 62: 6447–6450, 2002.

Boudewijn J. M. Braakhuis, C. René Leemans, Ruud H. Brakenhoff

Cancer Res (2003) 63 (16): 5167–5169.

Published: 26 August 2003

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Journal Articles

A Genetic Explanation of Slaughter’s Concept of Field Cancerization: Evidence and Clinical Implications

Boudewijn J. M. Braakhuis, Maarten P. Tabor, J. Alain Kummer, C. René Leemans, Ruud H. Brakenhoff

Cancer Res (2003) 63 (8): 1727–1730.

Published: 15 April 2003

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NARROW

Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC

Abstract 4638: Targeted therapy of precancerous fields in the mucosal linings of the head and neck

Abstract 4637: Chk1 inhibition: a promising targeted treatment for head and neck squamous cell carcinoma

Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer

Abstract 2488: Novel candidate protein biomarkers for cisplatin response prediction in non-small cell lung cancer.

Abstract 338: Truncating TP53 mutations have prognostic significance in head and neck squamous cell carcinoma

Abstract 4122: Multi-center validation of a lymph node metastasis gene-expression signature for head and neck squamous cell carcinomas

Abstract 4823: Single cell analysis of head and neck squamous cell carcinoma cells isolated from primary tumors and matched metastases

Abstract 5100: Secretome proteomics to identify indicators for lung cancer treatment response prediction and monitoring

Abstract 1750: Identification of genes involved in chemoradiation response of head and neck cancer by functional genetic screens

Human Lymphoblastoid Proteome Analysis Reveals a Role for the Inhibitor of Acetyltransferases Complex in DNA Double-Strand Break Response

Different genome wide DNA copy number alterations in head and neck squamous cell carcinomas with or without transcriptionally active human papillomavirus.

Multiplex Ligation-dependent Probe Amplification (MLPA), a novel genetic test for non-invasive detection of oral preneoplastic lesions

Generation and Molecular Characterization of Head and Neck Squamous Cell Lines of Fanconi Anemia Patients

Correspondence re: M. P. Rosin et al ., 3p14 and 9p21 Loss Is a Simple Tool for Predicting Second Oral Malignancy at Previously Treated Oral Cancer Sites. Cancer Res., 62: 6447–6450, 2002.

A Genetic Explanation of Slaughter’s Concept of Field Cancerization: Evidence and Clinical Implications

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