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Ruth Scherz-Shouval
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Journal Articles

Unlocking the Role of Age-Related Changes to Fibroblasts in Pancreatic Cancer

Available to Purchase
Achinoam Isaacson, Debra Barki, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2024) 84 (8): 1185–1187.
https://doi.org/10.1158/0008-5472.CAN-24-0439
Published: 15 April 2024
View articletitled, Unlocking the Role of Age-Related Changes to Fibroblasts in Pancreatic Cancer
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Journal Articles

Breast Cancer–Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche

Available to Purchase
Noam Cohen, Dhanashree Mundhe, Sarah K. Deasy, Omer Adler, Nour Ershaid, Tamar Shami, Oshrat Levi-Galibov, Rina Wassermann, Ruth Scherz-Shouval, Neta Erez
Journal: Cancer Research
Cancer Res (2023) 83 (20): 3354–3367.
https://doi.org/10.1158/0008-5472.CAN-22-3707
Published: 13 October 2023
View articletitled, Breast Cancer–Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche
Open the PDF for Breast Cancer–Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche in another window
Includes: Supplementary data
Journal Articles

Abstract 5998: Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma

Free
Coral Halperin, Joschka Hey, Dieter Weichenhan, Yaniv Stein, Shimrit Mayer, Pavlo Lustik, Christoph Plass, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5998.
https://doi.org/10.1158/1538-7445.AM2023-5998
Published: 04 April 2023
View articletitled, Abstract 5998: Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma
Journal Articles

Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma

Available to Purchase
Coral Halperin, Joschka Hey, Dieter Weichenhan, Yaniv Stein, Shimrit Mayer, Pavlo Lutsik, Christoph Plass, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2022) 82 (22): 4139–4152.
https://doi.org/10.1158/0008-5472.CAN-22-0209
Published: 15 November 2022
View articletitled, Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma
Open the PDF for Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma in another window
Includes: Supplementary data
Journal Articles

T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy

Open Access
Jozafina Haj-Shomaly, Avital Vorontsova, Tamar Barenholz-Cohen, Oshrat Levi-Galibov, Mahesh Devarasetty, Michael Timaner, Ziv Raviv, Tim J. Cooper, Shay Soker, Peleg Hasson, Daphne Weihs, Ruth Scherz-Shouval, Yuval Shaked
Journal: Cancer Research
Cancer Res (2022) 82 (2): 278–291.
https://doi.org/10.1158/0008-5472.CAN-21-1012
Published: 15 January 2022
View articletitled, T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy
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Includes: Supplementary data
Journal Articles

Abstract LB204: HSF1 promotes inflammation induced tumor development through ECM remodeling

Free
Oshrat Levi Galibov, Hagar Lavon, Rina Wassermann-Dozorets, Meirav Pevsner-Fischer, Shimrit Mayer, Esther Wershof, Yaniv Stein, Lauren E. Brown, Wenhan Zhang, Gil Friedman, Reinat Nevo, Ofra Golani, Lior H. Katz, Rona Yaeger, Ido Laish, John A. Porco, Erik Sahai, Dror S Shouval, David Kelsen, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB204.
https://doi.org/10.1158/1538-7445.AM2021-LB204
Published: 01 July 2021
View articletitled, Abstract LB204: HSF1 promotes inflammation induced tumor development through ECM remodeling
Journal Articles

Abstract LB244: The role of stromal Per2 in regulation of tumorigenesis

Free
Shimrit Mayer, Lee Shaashua, Chen Lior, Hagar Lavon, Alexander Novoselsky, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB244.
https://doi.org/10.1158/1538-7445.AM2021-LB244
Published: 01 July 2021
View articletitled, Abstract LB244: The role of stromal Per2 in regulation of tumorigenesis
Journal Articles

Abstract LB009: Dynamic changes in the compositions of cancer associated-fibroblasts correlate with clinical outcome in breast cancer

Free
Gil Friedman, Oshrat Levi-Galibov, Eyal David, Chamutal Bornstein, Amir Giladi, Maya Dadiani, Avi Mayo, Coral Halperin, Meirav Pevsner-Fischer, Hagar Lavon, Shimrit Mayer, Reinat Nevo, Yaniv Stein, Nora Balint-Lahat, Iris Barshack, H. Raza Ali, Carlos Caldas, Einav Nili Gal-Yam, Uri Alon, Ido Amit, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB009.
https://doi.org/10.1158/1538-7445.AM2021-LB009
Published: 01 July 2021
View articletitled, Abstract LB009: Dynamic changes in the compositions of cancer associated-fibroblasts correlate with clinical outcome in breast cancer
Journal Articles

Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1–Mediated Secretion of Extracellular Vesicles

Available to Purchase
Nil Grunberg, Meirav Pevsner-Fischer, Tal Goshen-Lago, Judith Diment, Yaniv Stein, Hagar Lavon, Shimrit Mayer, Oshrat Levi-Galibov, Gil Friedman, Yifat Ofir-Birin, Li-Jyun Syu, Cristina Migliore, Eyal Shimoni, Salomon M. Stemmer, Baruch Brenner, Andrzej A. Dlugosz, David Lyden, Neta Regev-Rudzki, Irit Ben-Aharon, Ruth Scherz-Shouval
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1639–1653.
https://doi.org/10.1158/0008-5472.CAN-20-2756
Published: 01 April 2021
View articletitled, Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1–Mediated Secretion of Extracellular Vesicles
Open the PDF for Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1–Mediated Secretion of Extracellular Vesicles in another window
Includes: Supplementary data
Journal Articles

Abstract PR07: Mechanisms of stromal reprogramming mediated by heat shock factor 1

Free
Ruth Scherz-Shouval, Marc L. Mendillo, Giorgio Gaglia, Irit Ben-Aharon, Andrew H. Beck, Luke Whitesell, Susan Lindquist
Journal: Cancer Research
Cancer Res (2016) 76 (15_Supplement): PR07.
https://doi.org/10.1158/1538-7445.TME16-PR07
Published: 28 July 2016
View articletitled, Abstract PR07: Mechanisms of stromal reprogramming mediated by heat shock factor 1
Journal Articles

Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors

Free
Alexander F. Bagley, Ruth Scherz-Shouval, Peter A. Galie, Angela Q. Zhang, Jeffrey Wyckoff, Luke Whitesell, Christopher S. Chen, Susan Lindquist, Sangeeta N. Bhatia
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (16): 3255–3267.
https://doi.org/10.1158/0008-5472.CAN-15-0325
Published: 13 August 2015
View articletitled, Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
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Includes: Supplementary data
Journal Articles

Abstract A23: Cell autonomous and nonautonomous activities of heat shock factor 1 support tumor initiation, progression, and metastasis

Free
Ruth Scherz-Shouval, Sandro Santagata, Martina Koeva, Luke Whitesell, Susan Lindquist
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): A23.
https://doi.org/10.1158/1538-7445.TIM2013-A23
Published: 01 May 2014
View articletitled, Abstract A23: Cell autonomous and nonautonomous activities of heat shock factor 1 support tumor initiation, progression, and metastasis