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Ruth Lupu
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Journal Articles

Abstract 3723: Fatty acid synthase: A new therapeutic target for pancreatic cancer

Travis Vander Steen, Li Ding, Yu Zhang, George Kemble, Daniel Billadeau, Ruth Lupu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3723.
https://doi.org/10.1158/1538-7445.AM2019-3723
Published: 01 July 2019
View articletitled, Abstract 3723: Fatty acid synthase: A new therapeutic target for pancreatic cancer
Journal Articles

Abstract 708: Targeting fatty acid synthase induces apoptosis and senescence

Travis Van der Steen, George Kemble, Ruth Lupu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 708.
https://doi.org/10.1158/1538-7445.AM2019-708
Published: 01 July 2019
View articletitled, Abstract 708: Targeting fatty acid synthase induces apoptosis and senescence
Journal Articles

Abstract 318: Inhibition of FASN induces apoptosis and senescence in breast cancer

Travis Vander Steen, Ruth Lupu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 318.
https://doi.org/10.1158/1538-7445.AM2018-318
Published: 01 July 2018
View articletitled, Abstract 318: Inhibition of FASN induces apoptosis and senescence in breast cancer
Journal Articles

Abstract 133: Identification of a key region in the HER2 subdomain III required for transformation capability

Barbara Schroeder, Ghiara Lugo, Javier Menendez, Ingrid Espinoza, Ruth Lupu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 133.
https://doi.org/10.1158/1538-7445.AM2015-133
Published: 01 August 2015
View articletitled, Abstract 133: Identification of a key region in the HER2 subdomain III required for transformation capability
Journal Articles

Abstract LB-196: Preventing breast cancer metastases with an anti-angiogenic and anticancer RGD-bearing nanomedicine

Anat Eldar-Boock, Dikla Ben-Shushan, Joaquin Sanchis, Ruth Lupu, Maria J. Vicent, Ronit Satchi-Fainaro
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-196.
https://doi.org/10.1158/1538-7445.AM2014-LB-196
Published: 01 October 2014
View articletitled, Abstract LB-196: Preventing breast cancer metastases with an anti-angiogenic and anticancer RGD-bearing nanomedicine
Journal Articles

Abstract 2713: Small-molecule FASN inhibitors promote growth inhibition growth and apoptosis of breast cancer

Ruth Lupu, Anatilde Gonzalez Guerrico, Ashwani Khurana, Timothy Heuer, George Kemble, Chandra Mohan KVP
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2713.
https://doi.org/10.1158/1538-7445.AM2014-2713
Published: 01 October 2014
View articletitled, Abstract 2713: Small-molecule FASN inhibitors promote growth inhibition growth and apoptosis of breast cancer
Journal Articles

Abstract 3506: Heregulin induces transformation of mammary epithelial cells via HER3 activation

Ruth Lupu, Ashwani Khurana, Ghiara Lugo, Anatilde Gonzalez Guerrico
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3506.
https://doi.org/10.1158/1538-7445.AM2014-3506
Published: 01 October 2014
View articletitled, Abstract 3506: Heregulin induces transformation of mammary epithelial cells via HER3 activation
Journal Articles

Abstract 1737: Pharmacological inhibition of fatty acid synthase regulates BH3-only proteins and sensitizes breast cancer cells to a small molecule Bcl-2/Bcl-xL inhibitor to induce apoptosis.

Chandra Mohan Kurapaty Venkatapoorna, Ingrid Espinoza, Scott H Kaufmann, Ruth Lupu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1737.
https://doi.org/10.1158/1538-7445.AM2013-1737
Published: 15 April 2013
View articletitled, Abstract 1737: Pharmacological inhibition of fatty acid synthase regulates BH3-only proteins and sensitizes breast cancer cells to a small molecule Bcl-2/Bcl-xL inhibitor to induce apoptosis.
Journal Articles

Abstract 3896: A metabolic enzyme as a pro-angiogenic activator in premalignant mammary cells.

Anatilde M. Gonzalez-Guerrico, Ingrid Espinoza, Ruth Lupu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3896.
https://doi.org/10.1158/1538-7445.AM2013-3896
Published: 15 April 2013
View articletitled, Abstract 3896: A metabolic enzyme as a pro-angiogenic activator in premalignant mammary cells.
Journal Articles

Abstract 5596: Linkage between the lipogenic pathway and the progression of breast carcinomas.

Anatilde M. Gonzalez-Guerrico, Cheol Park-Hong, Celina Kleer, Ingrid Espinoza, Ruth Lupu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5596.
https://doi.org/10.1158/1538-7445.AM2013-5596
Published: 15 April 2013
View articletitled, Abstract 5596: Linkage between the lipogenic pathway and the progression of breast carcinomas.
Journal Articles

Abstract 3854: Gamma-linolenic Acid (GLA) sensitizes pancreatic cancer cells to gemcitabine

Ruth Lupu, Robert Busby, Park-Hong Cheol, Ingrid Espinoza
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3854.
https://doi.org/10.1158/1538-7445.AM2012-3854
Published: 15 April 2012
View articletitled, Abstract 3854: Gamma-linolenic Acid (GLA) sensitizes pancreatic cancer cells to gemcitabine
Journal Articles

Abstract 1846: Cyr61 a therapeutic target for breast carcinomas

Chandra Mohan Kurapaty Venkatapoorna, Ingrid Espinoza, Cheol-Hong Park, Robert Busby, Elizabeth Wiley, Alfred Rademaker, Ruth Lupu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1846.
https://doi.org/10.1158/1538-7445.AM2012-1846
Published: 15 April 2012
View articletitled, Abstract 1846: Cyr61 a therapeutic target for breast carcinomas
Journal Articles

Abstract 5225: Correlation between αvβ3 integrin expression, paclitaxel resistance and RGD-bearing conjugate efficacy

Anat Eldar-Boock, Joaquin Sanchis, Ruth Lupu, Maria J. Vicent, Ronit Satchi-Fainaro
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5225.
https://doi.org/10.1158/1538-7445.AM2012-5225
Published: 15 April 2012
View articletitled, Abstract 5225: Correlation between αvβ3 integrin expression, paclitaxel resistance and RGD-bearing conjugate efficacy
Journal Articles

Abstract 271: Heregulin internalization to the nucleus is mediated via binding to nucleolin

Lin Yang, Ruth Lupu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 271.
https://doi.org/10.1158/1538-7445.AM10-271
Published: 15 April 2010
View articletitled, Abstract 271: Heregulin internalization to the nucleus is mediated via binding to nucleolin
Journal Articles

Abstract 209: Gamma linolenic acid sensitizes pancreatic cancer cells to chemotherapy

Ingrid C. Espinoza, Robert Busby, Ruth Lupu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 209.
https://doi.org/10.1158/1538-7445.AM10-209
Published: 15 April 2010
View articletitled, Abstract 209: Gamma linolenic acid sensitizes pancreatic cancer cells to chemotherapy
Journal Articles

Abstract #3852: CCN1/ER/FOXO3a: A new connection in the hormonal response in breast cancer.

Ingrid Espinoza, Hong Liu, Robert C. Busby, Ruth Lupu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3852.
Published: 01 May 2009
View articletitled, Abstract #3852: CCN1/ER/FOXO3a: A new connection in the hormonal response in breast cancer.
Journal Articles

Abstract #LB-197: Disruption of ligand induced HER2:HER3 inhibits tumor growth death and increases Paclitaxel-sensitivity in Breast Cancer Cells .

Jing Li, Ingrid Espinoza, Hong Liu, Ruth Lupu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-197.
Published: 01 May 2009
View articletitled, Abstract #LB-197: Disruption of ligand induced HER2:HER3 inhibits tumor growth death and increases Paclitaxel-sensitivity in Breast Cancer Cells .
Journal Articles

Abstract #4419: HER receptors and fatty acid synthase in ovarian cancer: Molecular rationales for co-targeting approaches

Thomas Grunt, Renate Wagner, Michael Grusch, Walter Berger, Christian Singer, Brigitte Marian, Christoph Zielinski, Ruth Lupu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4419.
Published: 01 May 2009
View articletitled, Abstract #4419: HER receptors and fatty acid synthase in ovarian cancer: Molecular rationales for co-targeting approaches
Journal Articles

Domain III of HER2 extracellular domain (ECD) inhibits oncogenic signaling from HER2

Ying Zhang, Javier Menendez, Susan Peirce, Ruth Lupu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-148.
Published: 01 May 2008
View articletitled, Domain III of HER2 extracellular domain (ECD) inhibits oncogenic signaling from HER2
Journal Articles

A new cross-talk between MT1-MMP:β3-integrin receptor and ERα: Hormonal regulation and breast cancer progression.

Clara Diestre, Ingrid Espinoza, Erik Thompson, Ruth Lupu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5448.
Published: 01 May 2008
View articletitled, A new cross-talk between MT1-MMP:β3-integrin receptor and ERα: Hormonal regulation and breast cancer progression.