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Ruth J. Muschel
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Journal Articles

Abstract 3947: Mass-spectrometry analysis of metastatic matrisome from MC38 experimental liver metastasis

Arseniy E. Yuzhalin, Dihua Yu, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3947.
https://doi.org/10.1158/1538-7445.AM2020-3947
Published: 15 August 2020
View article titled, Abstract 3947: Mass-spectrometry analysis of metastatic matrisome from MC38 experimental liver metastasis
Journal Articles

A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities

Ruth J. Muschel, Ester M. Hammond, Mark W. Dewhirst
Journal: Cancer Research
Cancer Res (2020) 80 (5): 927–928.
https://doi.org/10.1158/0008-5472.CAN-19-4045
Published: 02 March 2020
View article titled, A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities
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Journal Articles

Abstract 4196: Aspirin inhibits metastasis in the intravascular phase through the blockade of COX-1-TXA2 pathway in platelets

Serena Lucotti, Camilla Cerutti, Magali Soyer, Ana M. Gil-Bernabé, Ana L. Gomes, Philip D. Allen, Sean Smart, Bostjan Markelc, Karla Watson, Paul C. Armstrong, Jane A. Mitchell, Timothy D. Warner, Anne J. Ridley, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4196.
https://doi.org/10.1158/1538-7445.AM2018-4196
Published: 01 July 2018
View article titled, Abstract 4196: Aspirin inhibits metastasis in the intravascular phase through the blockade of COX-1-TXA<sub>2</sub> pathway in platelets
Journal Articles

Abstract 998: Radiation-induced immunosuppressive macrophages limit CD8 T-cell mediated tumor killing

Keaton I. Jones, Jiske Tiersma, Jon Buzzelli, Alex Gordon-Weeks, Arseniy Yuzhalin, Jaehong Im, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 998.
https://doi.org/10.1158/1538-7445.AM2018-998
Published: 01 July 2018
View article titled, Abstract 998: Radiation-induced immunosuppressive macrophages limit CD8 T-cell mediated tumor killing
Journal Articles

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer

Zenobia D'Costa, Keaton Jones, Abul Azad, Ruud van Stiphout, Su Y. Lim, Ana L. Gomes, Paul Kinchesh, Sean C. Smart, W. Gillies McKenna, Francesca M. Buffa, Owen J. Sansom, Ruth J. Muschel, Eric O'Neill, Emmanouil Fokas
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5952–5962.
https://doi.org/10.1158/0008-5472.CAN-16-2833
Published: 31 October 2017
View article titled, Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer
Open the PDF for Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1087: Accumulation of CD11b+ Gr1 myeloid cells in liver metastases stimulates tumor growth and angiogenesis

Su Yin Lim, Alex Gordon-Weeks, Lei Zhao, Veerle Kersemans, Danny Allen, Sean Smart, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1087.
https://doi.org/10.1158/1538-7445.AM2014-1087
Published: 01 October 2014
View article titled, Abstract 1087: Accumulation of CD11b+ Gr1 myeloid cells in liver metastases stimulates tumor growth and angiogenesis
Journal Articles

Abstract LB-324: The response of infiltrating and resident macrophages to melanoma challenge in the mouse lung: Involvement of the CC-chemokine axis in the recruitment of pro-tumoral macrophages.

Thomas T. Tapmeier, Annamaria Gal, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-324.
https://doi.org/10.1158/1538-7445.AM2013-LB-324
Published: 15 April 2013
View article titled, Abstract LB-324: The response of infiltrating and resident macrophages to melanoma challenge in the mouse lung: Involvement of the CC-chemokine axis in the recruitment of pro-tumoral macrophages.
Journal Articles

Abstract 402: Plasticity of tumor associated macrophages in a metastatic melanoma model in the mouse

Annamaria Gal, Thomas T. Tapmeier, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 402.
https://doi.org/10.1158/1538-7445.AM2012-402
Published: 15 April 2012
View article titled, Abstract 402: Plasticity of tumor associated macrophages in a metastatic melanoma model in the mouse
Journal Articles

Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature

Emmanouil Fokas, Jae Hong Im, Sally Hill, Sabira Yameen, Michael Stratford, John Beech, Wolfgang Hackl, Sauveur-Michel Maira, Eric J. Bernhard, W. Gillies McKenna, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2012) 72 (1): 239–248.
https://doi.org/10.1158/0008-5472.CAN-11-2263
Published: 02 January 2012
View article titled, Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
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Includes: Supplementary data
Journal Articles

Abstract 2847: Host angiopoietin-2 inhibits tumor growth and angiogenesis in the liver

Jae Hong Im, Lukxmi Balathasan, Sabira Yameen, Thomas Tapmeier, Sally Hill, Eric Bernhard, D.Lee Gorden, Karoline Kruse, Hellmut Augustin, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2847.
https://doi.org/10.1158/1538-7445.AM2011-2847
Published: 15 April 2011
View article titled, Abstract 2847: Host angiopoietin-2 inhibits tumor growth and angiogenesis in the liver
Journal Articles

Matrix Metalloproteinase-9 Regulates Tumor Cell Invasion through Cleavage of Protease Nexin-1

Danmei Xu, Chad M. McKee, Yunhong Cao, Yunchuan Ding, Benedikt M. Kessler, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2010) 70 (17): 6988–6998.
https://doi.org/10.1158/0008-5472.CAN-10-0242
Published: 31 August 2010
View article titled, Matrix Metalloproteinase-9 Regulates Tumor Cell Invasion through Cleavage of Protease Nexin-1
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Includes: Supplementary data
Journal Articles

A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown

Geoff S. Higgins, Remko Prevo, Yin-Fai Lee, Thomas Helleday, Ruth J. Muschel, Steve Taylor, Michio Yoshimura, Ian D. Hickson, Eric J. Bernhard, W. Gillies McKenna
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2984–2993.
https://doi.org/10.1158/0008-5472.CAN-09-4040
Published: 31 March 2010
View article titled, A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown
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Includes: Supplementary data
Journal Articles

Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling

Naseer Qayum, Ruth J. Muschel, Jae Hong Im, Lukxmi Balathasan, Cameron J. Koch, Sonal Patel, W. Gillies McKenna, Eric J. Bernhard
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6347–6354.
https://doi.org/10.1158/0008-5472.CAN-09-0657
Published: 29 July 2009
View article titled, Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
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Includes: Supplementary data
Journal Articles

Guanylyl Cyclase C Prevents Colon Cancer Metastasis by Regulating Tumor Epithelial Cell Matrix Metalloproteinase-9

Wilhelm J. Lubbe, David S. Zuzga, Zengyi Zhou, Weili Fu, Joshua Pelta-Heller, Ruth J. Muschel, Scott A. Waldman, Giovanni M. Pitari
Journal: Cancer Research
Cancer Res (2009) 69 (8): 3529–3536.
https://doi.org/10.1158/0008-5472.CAN-09-0067
Published: 15 April 2009
View article titled, Guanylyl Cyclase C Prevents Colon Cancer Metastasis by Regulating Tumor Epithelial Cell Matrix Metalloproteinase-9
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Journal Articles

Abnormal Cytokinesis after X-Irradiation in Tumor Cells that Override the G2 DNA Damage Checkpoint

Haomin Huang, Lynda Fletcher, Neil Beeharry, Rene Daniel, Gary Kao, Tim J. Yen, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3724–3732.
https://doi.org/10.1158/0008-5472.CAN-08-0479
Published: 15 May 2008
View article titled, Abnormal Cytokinesis after X-Irradiation in Tumor Cells that Override the G<sub>2</sub> DNA Damage Checkpoint
Open the PDF for Abnormal Cytokinesis after X-Irradiation in Tumor Cells that Override the G<sub>2</sub> DNA Damage Checkpoint in another window
Includes: Multimedia, Supplementary data
Journal Articles

Use of multiphoton microscopy to study earliest steps in liver metastasis

David Lee Gorden, Jae H. Im, Weili Fu, Lynn M. Matrisian, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 814.
Published: 15 April 2006
View article titled, Use of multiphoton microscopy to study earliest steps in liver metastasis
Journal Articles

HIV Protease Inhibitors Block Akt Signaling and Radiosensitize Tumor Cells Both In vitro and In vivo

Anjali K. Gupta, George J. Cerniglia, Rosemarie Mick, W. Gillies McKenna, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2005) 65 (18): 8256–8265.
https://doi.org/10.1158/0008-5472.CAN-05-1220
Published: 15 September 2005
View article titled, HIV Protease Inhibitors Block Akt Signaling and Radiosensitize Tumor Cells Both <em>In vitro</em> and <em>In vivo</em>
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Journal Articles

Selective Inhibition of Ras, Phosphoinositide 3 Kinase, and Akt Isoforms Increases the Radiosensitivity of Human Carcinoma Cell Lines

In-Ah Kim, Sun-Sik Bae, Annemarie Fernandes, JunMin Wu, Ruth J. Muschel, W. Gillies McKenna, Morris J. Birnbaum, Eric J. Bernhard
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7902–7910.
https://doi.org/10.1158/0008-5472.CAN-05-0513
Published: 01 September 2005
View article titled, Selective Inhibition of Ras, Phosphoinositide 3 Kinase, and Akt Isoforms Increases the Radiosensitivity of Human Carcinoma Cell Lines
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Journal Articles

The use of HIV protease inhibitors as radiosensitizers

Anjali K. Gupta, George J. Cerniglia, Rosemarie Mick, Ruth J. Muschel, W. Gillies McKenna
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 285.
Published: 01 May 2005
View article titled, The use of HIV protease inhibitors as radiosensitizers
Journal Articles

Coagulation Facilitates Tumor Cell Spreading in the Pulmonary Vasculature during Early Metastatic Colony Formation

Jae Hong Im, Weili Fu, Hui Wang, Sujata K. Bhatia, Daniel A. Hammer, M. Anna Kowalska, Ruth J. Muschel
Journal: Cancer Research
Cancer Res (2004) 64 (23): 8613–8619.
https://doi.org/10.1158/0008-5472.CAN-04-2078
Published: 01 December 2004
View article titled, Coagulation Facilitates Tumor Cell Spreading in the Pulmonary Vasculature during Early Metastatic Colony Formation
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