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Ruth A. Keri
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Journal Articles

Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer

Katrina M. Piemonte, Natasha N. Ingles, Kristen L. Weber-Bonk, Mitchell J. Valentine, Parth R. Majmudar, Salendra Singh, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2024) 84 (21): 3556–3573.
https://doi.org/10.1158/0008-5472.CAN-23-2558
Published: 04 November 2024
View article titled, Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer
Open the PDF for Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 853: Assessment of racial and ethnic disparities in environmental exposure-related cancer burden

Jessica R. Bobbitt, Fangzhou Liu, Jennifer Cullen, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 853.
https://doi.org/10.1158/1538-7445.AM2024-853
Published: 22 March 2024
View article titled, Abstract 853: Assessment of racial and ethnic disparities in environmental exposure-related cancer burden
Journal Articles

TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis

Lindsey J. Anstine, Parth R. Majmudar, Amy Aponte, Salendra Singh, Ran Zhao, Kristen L. Weber-Bonk, Fadi W. Abdul-Karim, Mitchell Valentine, Darcie D. Seachrist, Katelyn E. Grennel-Nickelson, Leslie Cuellar-Vite, Gina M. Sizemore, Steven T. Sizemore, Bryan M. Webb, Cheryl L. Thompson, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2023) 83 (7): 997–1015.
https://doi.org/10.1158/0008-5472.CAN-22-3133
Published: 04 April 2023
View article titled, TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Open the PDF for TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 2301: Targeting the MUVB complex or downstream G2/M proteins potentiates CDK4/6 inhibitor efficacy in breast cancer

Leslie Cuellar-Vite, Kristen Weber-Bonk, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2301.
https://doi.org/10.1158/1538-7445.AM2022-2301
Published: 15 June 2022
View article titled, Abstract 2301: Targeting the MUVB complex or downstream G2/M proteins potentiates CDK4/6 inhibitor efficacy in breast cancer
Journal Articles

LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance

Melyssa S. Roberts, Jennifer M. Sahni, Morgan S. Schrock, Katrina M. Piemonte, Kristen L. Weber-Bonk, Darcie D. Seachrist, Stefanie Avril, Lindsey J. Anstine, Salendra Singh, Steven T. Sizemore, Vinay Varadan, Matthew K. Summers, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2020) 80 (8): 1693–1706.
https://doi.org/10.1158/0008-5472.CAN-19-3466
Published: 15 April 2020
View article titled, LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance
Open the PDF for LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract P2-04-01: Cyclin dependent kinase 7 ( CDK7) inhibition promotes genomic instability and mitotic catastrophe in triple negative breast cancer

Bryan M Webb, Melyssa Shively, Katrina Piemonte, Jennifer M Sahni, Ruth A Keri
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-04-01.
https://doi.org/10.1158/1538-7445.SABCS19-P2-04-01
Published: 15 February 2020
View article titled, Abstract P2-04-01: Cyclin dependent kinase 7 ( CDK7) inhibition promotes genomic instability and mitotic catastrophe in triple negative breast cancer
Journal Articles

Abstract 2097: LIN9 regulation of NEK2 underlies taxol resistance in triple-negative breast cancer

Melyssa S. Shively, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2097.
https://doi.org/10.1158/1538-7445.AM2019-2097
Published: 01 July 2019
View article titled, Abstract 2097: LIN9 regulation of NEK2 underlies taxol resistance in triple-negative breast cancer
Journal Articles

Abstract 32: BCL11A is necessary for the expression of extracellular matrix genes and metastatic progression of triple-negative breast cancer

Darcie D. Seachrist, Natasha N. Ingles, Molly M. Hannigan, Donny D. Licatalosi, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 32.
https://doi.org/10.1158/1538-7445.AM2018-32
Published: 01 July 2018
View article titled, Abstract 32: BCL11A is necessary for the expression of extracellular matrix genes and metastatic progression of triple-negative breast cancer
Journal Articles

Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors

Jennifer M. Sahni, Sylvia S. Gayle, Bryan M. Webb, Kristen L. Weber-Bonk, Darcie D. Seachrist, Salendra Singh, Steven T. Sizemore, Nicole A. Restrepo, Gurkan Bebek, Peter C. Scacheri, Vinay Varadan, Matthew K. Summers, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5395–5408.
https://doi.org/10.1158/0008-5472.CAN-17-1571
Published: 01 October 2017
View article titled, Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors
Open the PDF for Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors in another window
Includes: Supplementary data
Journal Articles

Combined SFK/mTOR Inhibition Prevents Rapamycin-Induced Feedback Activation of AKT and Elicits Efficient Tumor Regression

Jennifer L. Yori, Kristen L. Lozada, Darcie D. Seachrist, Jonathan D. Mosley, Fadi W. Abdul-Karim, Christine N. Booth, Chris A. Flask, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4762–4771.
https://doi.org/10.1158/0008-5472.CAN-13-3627
Published: 01 September 2014
View article titled, Combined SFK/mTOR Inhibition Prevents Rapamycin-Induced Feedback Activation of AKT and Elicits Efficient Tumor Regression
Open the PDF for Combined SFK/mTOR Inhibition Prevents Rapamycin-Induced Feedback Activation of AKT and Elicits Efficient Tumor Regression in another window
Includes: Supplementary data
Journal Articles

Abstract LB-221: Inhibition of rapamycin-induced feedback activation of AKT with dasatinib induces complete tumor regression in a preclinical model of breast cancer.

Jennifer L. Yori, Kristen Lozada, Darcie D. Seachrist, Jonathan Mosley, Fadi W. Abdul-Karim, Christine N. Booth, Chris A. Flask, Ruth A. Keri
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-221.
https://doi.org/10.1158/1538-7445.AM2013-LB-221
Published: 15 April 2013
View article titled, Abstract LB-221: Inhibition of rapamycin-induced feedback activation of AKT with dasatinib induces complete tumor regression in a preclinical model of breast cancer.