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Journal Articles

Abstract 3975: Clonal emergence of resistance to methotrexate in osteosarcoma barcoded PDX cells

Giuseppe Longo, Sylvester Jusu, Zhongting Zhang, Zhaohui Xu, Wendong Zhang, Michael Roth, Rui Yang, Douglas Harrison, Jonathan Gill, Richard Gorlick
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3975.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3975
Published: 15 June 2022
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Abstract 6188: Targeted inhibition of the E3 ligase SCFSkp2/Cks1 has survival benefit and antitumor activity in osteosarcoma

Jichuan Wang, Alexander Ferrena, Ranxin Zhang, Swapnil Singh, Hongling Zhao, Deyou Zheng, Hasibagan Borjihan, Waleed Al-Harden, Janet Tingling, Rui Yang, David S. Geller, Bang H. Hoang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6188.
DOI: https://doi.org/10.1158/1538-7445.AM2022-6188
Published: 15 June 2022
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Journal Articles

Abstract 2008: Targeting SKP2 by p27 Inhibits stemness and prolong the survival in osteosarcoma

Jichuan Wang, Osama Aldahamsheh, Alexander Ferrena, Swapnil Singh, Amit Singla, Hasibagan Borjihan, Simon Yaguare, Valentina Viscarret, Janet Tingling, Xiaolin Zi, Yungtai Lo, Richard Gorlick, Deyou Zheng, Edward L. Schwartz, Hongling Zhao, Rui Yang, David S. Geller, Bang H. Hoang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2008.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2008
Published: 01 July 2021
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Journal Articles

Abstract 5930: Targeting Skp2 in synovial sarcoma reduces tumor-initiating properties and promotes apoptosis

Jichuan Wang, Kenji Sato, Ed O'Donnell, Amit Singla, Simon Yaguare, Osama Aldahamsheh, Brian Batko, Hasibagan Borjihan, Janet Tingling, Daniel A Weiser, David M Loeb, Richard Gorlick, Edward L Schwartz, Rui Yang, Xiaolin Zi, Hongling Zhao, David S Geller, Bang H Hoang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5930.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5930
Published: 15 August 2020
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Journal Articles

MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation

Landon J. Hansen, Ran Sun, Rui Yang, Simranjit X. Singh, Lee H. Chen, Christopher J. Pirozzi, Casey J. Moure, Carlee Hemphill, Austin B. Carpenter, Patrick Healy, Ryan C. Ruger, Chin-Pu J. Chen, Paula K. Greer, Fangping Zhao, Ivan Spasojevic, Carole Grenier, Zhiqing Huang, Susan K. Murphy, Roger E. McLendon, Henry S. Friedman, Allan H. Friedman, James E. Herndon, II, John H. Sampson, Stephen T. Keir, Darell D. Bigner, Hai Yan, Yiping He
Journal: Cancer Research
Cancer Res (2019) 79 (13): 3383–3394.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-1010
Published: 01 July 2019
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Includes: Supplementary data
Journal Articles

Abstract LB-117: Role of ectoenzymes CD39 and CD73 in the immune response to multiple myeloma

Rui Yang, Samah Elsaadi, Kristine Misund, Geir Slupphaug, Eline Menu, Carl Hay, Zac Cooper, Karin Vanderkerken, Magne Børset, Anne Marit Sponaas
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-117.
DOI: https://doi.org/10.1158/1538-7445.AM2018-LB-117
Published: 01 July 2018
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Journal Articles

A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53

Chao Mao, Xiang Wang, Yating Liu, Min Wang, Bin Yan, Yiqun Jiang, Ying Shi, Yi Shen, Xiaoli Liu, Weiwei Lai, Rui Yang, Desheng Xiao, Yan Cheng, Shuang Liu, Hu Zhou, Ya Cao, Weishi Yu, Kathrin Muegge, Herbert Yu, Yongguang Tao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (13): 3484–3496.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-3454
Published: 01 July 2018
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Includes: Supplementary data
Journal Articles

Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities

Matthew S. Waitkus, Christopher J. Pirozzi, Casey J. Moure, Bill H. Diplas, Landon J. Hansen, Austin B. Carpenter, Rui Yang, Zhaohui Wang, Brian O. Ingram, Edward D. Karoly, Robert P. Mohney, Ivan Spasojevic, Roger E. McLendon, Henry S. Friedman, Yiping He, Darell D. Bigner, Hai Yan
Journal: Cancer Research
Cancer Res (2018) 78 (1): 36–50.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-1352
Published: 02 January 2018
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Includes: Supplementary data
Journal Articles

Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation

Rui Yang, Lee H. Chen, Landon J. Hansen, Austin B. Carpenter, Casey J. Moure, Heng Liu, Christopher J. Pirozzi, Bill H. Diplas, Matthew S. Waitkus, Paula K. Greer, Huishan Zhu, Roger E. McLendon, Darell D. Bigner, Yiping He, Hai Yan
Journal: Cancer Research
Cancer Res (2017) 77 (22): 6097–6108.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-1018
Published: 14 November 2017
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Includes: Supplementary data
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Abstract 1950: Introducing c-Myc into transformed human mesenchymal stem cells and osteoblasts to recapitulate the osteosarcoma phenotype

Sajida Piperdi (Thein), Wendong Zhang, Daria Ivenitsky, Yidan Zhang, Yunjia Zhang, David S. Geller, Bang Hoang, Rui Yang, Jonathan B. Gill, Michael Roth, Richard Gorlick
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1950.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1950
Published: 01 July 2017
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Journal Articles

Abstract 920: ICAM-1(CD54) is involved in the osteogenic differentiation of mesenchymal stem cells and affects the progression of osteosarcoma cells

Yidan Zhang, Sajida Piperdi, Nikolas Zaphiros, Pratistha Koirala, Tingting Ren, Michael Roth, Jonathan Gill, Bang Hoang, David Geller, Rui Yang, Wendong Zhang, Xiuquan Du, Jinghang Zhang, Richard Gorlick
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 920.
DOI: https://doi.org/10.1158/1538-7445.AM2017-920
Published: 01 July 2017
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Journal Articles

Abstract 699: Clinical feasibility of chemotherapy monitoring for bone sarcoma patients with diffuse optical spectroscopic imaging

Hannah M. Peterson, Bang H. Hoang, David Geller, Richard Gorlick, Rui Yang, Jeremy Berger, Janet Tingling, Michael Roth, Jonathan Gill, Darren Roblyer
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 699.
DOI: https://doi.org/10.1158/1538-7445.AM2017-699
Published: 01 July 2017
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Abstract 697: Stage 1 in vivo evaluation of multi-receptor tyrosine-kinase inhibitor lenvatinib in osteosarcoma patient derived mouse xenograft models

Wendong Zhang, Michael E. Roth, Jonathan Gill, Sajida Piperdi, E. Anders Kolb, David S. Geller, Bang Hoang, Rui Yang, Richard Gorlick
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 697.
DOI: https://doi.org/10.1158/1538-7445.AM2017-697
Published: 01 July 2017
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Journal Articles

Abstract 2125: Flavokawain A, a kava chalcone, inhibits growth and invasion of human osteosarcoma cells by targeting Skp2

Yidan Zhang, Wendong Zhang, Nikolas Zaphiros, Xiuquan Du, Pratistha Koirala, Michael Roth, Jonathan Gill, Sajida Piperdi, David Geller, Rui Yang, Jinghang Zhang, Richard Gorlick, Xiaolin Zi, Tao Ji, Bang H. Hoang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2125.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2125
Published: 01 July 2017
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Journal Articles

Abstract 2471: Evaluation of CD47 expression and effects of CD47-SIRPα fusion protein in patients with osteosarcoma

Sajida Piperdi, Michael Roth, Nick Morriss, Christian Zinone, Wendong Zhang, Pratistha Koirala, David Geller, Bang Hoang, Rui Yang, Jonathan Gill, Richard Gorlick
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2471.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2471
Published: 15 July 2016
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Journal Articles

Abstract 2182: Flavokawain A and B from kava extract exhibits low toxicity and up-regulates tumor suppressor miRNAs in human osteosarcoma cells

Wendong Zhang, Jonathan Morris, Sajida Piperdi, Yi Guo, Tao Ji, Rui Yang, Michael Roth, Jonathan Gill, David S. Geller, Richard Gorlick, Kevin Jones, Xiaolin Zi, Bang H. Hoang
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2182.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2182
Published: 15 July 2016
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Journal Articles

Abstract 645: The effect of rhBMP-2 on in vitro osteosarcoma tumorigenesis and on pulmonary growth and development

David S. Geller, So Hak Chung, Wendong Zhang, Sajida Piperdi, Carrie Freeman, Bang Hoang, Rui Yang, Michael Roth, Jonathan Gill, Richard Gorlick
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 645.
DOI: https://doi.org/10.1158/1538-7445.AM2016-645
Published: 15 July 2016
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Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas

Genglin Jin, Zachary J. Reitman, Christopher G. Duncan, Ivan Spasojevic, David M. Gooden, B. Ahmed Rasheed, Rui Yang, Giselle Y. Lopez, Yiping He, Roger E. McLendon, Darell D. Bigner, Hai Yan
Journal: Cancer Research
Cancer Res (2013) 73 (2): 496–501.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-2852
Published: 16 January 2013
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Includes: Supplementary data
Journal Articles

Abstract LB-1: Discovery and optimization of orally bioavailable, selective and potent ATP-independent Akt inhibitors

Thomas C.K. Chan, Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Jason Hill, Steffi Koerner, Eoin Kelleher, Darin Kizer, Yanbin Liu, Jeff Link, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Robert Nicewonger, Uma Uppalapati, Rocio Palma, Jeff Szwaya, Manish Tandon, David Vensel, Laurie Volak, Erika Volckova, Neil Westland, Hui Wu, Rui-Yang Yang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-1.
DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-1
Published: 15 April 2012
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Abstract 3905: Synthesis and structure activity relationship of substituted N,6-diphenyl-5,6-dihydrobenzo[h]quinazolin-2-amine as inhibitors of fibroblast growth factor receptors (FGFR)

Syed M. Ali, Chris Brassard, Audra Dalton, Darin Kizer, Jean-Marc Lapierre, Yanbin Liu, Magdi Moussa, Rocio Palma, Manish Tandon, David Vensel, Erika Volckova, Jianqiang Wang, Neil Westlund, Hui Wu, Rui-Yang Yang, Craig Bates, Mayank Bhavsar, Cathy Bull, Sudharshan Eathiraj, Robert Nicewonger, Ron Savage, Carol Waghorne, Jennifer Castro, Enkeleda Nakuci, Chang-Rung Chen, Dennis S. France, Thomas C.K. Chan, Mark A. Ashwell
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3905.
DOI: https://doi.org/10.1158/1538-7445.AM2012-3905
Published: 15 April 2012
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