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Journal Articles

Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism

Free
Rosanna Dattilo, Carla Mottini, Emanuela Camera, Alessia Lamolinara, Noam Auslander, Ginevra Doglioni, Michela Muscolini, Wei Tang, Melanie Planque, Cristiana Ercolani, Simonetta Buglioni, Isabella Manni, Daniela Trisciuoglio, Alessandra Boe, Sveva Grande, Anna Maria Luciani, Manuela Iezzi, Gennaro Ciliberto, Stefan Ambs, Ruggero De Maria, Sarah-Maria Fendt, Eytan Ruppin, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (19): 4087–4102.
https://doi.org/10.1158/0008-5472.CAN-19-1184
Published: 02 October 2020
View articletitled, Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism
Open the PDF for Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism in another window
Includes: Supplementary data
Journal Articles

Abstract 2484: Non-canonical Hedgehog/Gli1 signaling drives lung adenocarcinoma stem cells survival and its targeting inhibits CSC-derived tumors

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Agnese Po, Marianna Silvano, Evelina Miele, Adriana Eramo, Matilde Todaro, Carlo Capalbo, Valentina Salvati, Giovanni Sette, Danilo Cucchi, Zein M. Besharat, Gianluca Canettieri, Lucia Di Marcotullio, Isabella Screpanti, Giorgio Stassi, Ruggero De Maria, Ann Zeuner, Enrico De Smaele, Elisabetta Ferretti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2484.
https://doi.org/10.1158/1538-7445.AM2016-2484
Published: 15 July 2016
View articletitled, Abstract 2484: Non-canonical Hedgehog/Gli1 signaling drives lung adenocarcinoma stem cells survival and its targeting inhibits CSC-derived tumors
Journal Articles

Abstract SY01-02: Targeting stem cell pathways in human cancer

Free
Ruggero De Maria, Marcello Maugeri-Saccà
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): SY01-02.
https://doi.org/10.1158/1538-7445.AM2016-SY01-02
Published: 15 July 2016
View articletitled, Abstract SY01-02: Targeting stem cell pathways in human cancer
Journal Articles

Abstract LB-040: Establishment of a predictive patient-derived xenograft model for renal cell carcinoma

Free
Simona Di Martino, Gabriele De Luca, Ludovica Grassi, Giulia Federici, Laura De Salvo, Anna Laura Di Pace, Antonio Addario, Giovanni Muto, Manuela Costantini, Mauro Biffoni, Michele Signore, Steno Sentinelli, Michele Milella, Michele Gallucci, Désirée Bonci, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-040.
https://doi.org/10.1158/1538-7445.AM2016-LB-040
Published: 15 July 2016
View articletitled, Abstract LB-040: Establishment of a predictive patient-derived xenograft model for renal cell carcinoma
Journal Articles

Abstract 4316: hMENA11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2 overexpressing breast cancer cells

Free
Paola Trono, Francesca Di Modugno, Rita Circo, Sheila Spada, Roberta Melchionna, Belinda Palermo, Mariangela Panetta, Silvia Matteoni, Silvia Soddu, Ruggero De Maria, Paola Nisticò
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4316.
https://doi.org/10.1158/1538-7445.AM2015-4316
Published: 01 August 2015
View articletitled, Abstract 4316: hMENA11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2 overexpressing breast cancer cells
Journal Articles

Erythropoietin Activates Cell Survival Pathways in Breast Cancer Stem–like Cells to Protect Them from Chemotherapy

Free
Matilde Todaro, Alice Turdo, Monica Bartucci, Flora Iovino, Rosanna Dattilo, Marco Biffoni, Giorgio Stassi, Giulia Federici, Ruggero De Maria, Ann Zeuner
Journal: Cancer Research
Cancer Res (2013) 73 (21): 6393–6400.
https://doi.org/10.1158/0008-5472.CAN-13-0248
Published: 31 October 2013
View articletitled, Erythropoietin Activates Cell Survival Pathways in Breast Cancer Stem–like Cells to Protect Them from Chemotherapy
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Journal Articles

Abstract 883: Cell-based selection of RNA-aptamers to specifically target glioblastoma cancer stem cells

Free
Cristina Quintavalle, Lucia Ricci-Vitiani, Carla Lucia Esposito, Simona Di Martino, Laura Cerchia, Ruggero De Maria, Vittorio de Franciscis, Gerolama Condorelli
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 883.
https://doi.org/10.1158/1538-7445.AM2012-883
Published: 15 April 2012
View articletitled, Abstract 883: Cell-based selection of RNA-aptamers to specifically target glioblastoma cancer stem cells
Journal Articles

Abstract 4911: Systems level network analysis of NCI60 cell lines by alignment of protein pathway activation modules with multiple -omic data fields and therapeutic response signatures

Free
Giulia Federici, Ruggero De Maria, Lance A. Liotta, Julia D. Wulfkuhle, Emanuel F. Petricoin
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4911.
https://doi.org/10.1158/1538-7445.AM2012-4911
Published: 15 April 2012
View articletitled, Abstract 4911: Systems level network analysis of NCI60 cell lines by alignment of protein pathway activation modules with multiple -omic data fields and therapeutic response signatures
Journal Articles

Abstract 3312: Protein activation pathway analysis of glioblastoma stem cells reveals potential novel biomarkers

Free
Giulia Federici, Michele Signore, Simona Di Martino, Federica Pelacchi, Ruggero De Maria, Lance A. Liotta, Emanuel F. Petricoin, Lucia Ricci-Vitiani
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3312.
https://doi.org/10.1158/1538-7445.AM2011-3312
Published: 15 April 2011
View articletitled, Abstract 3312: Protein activation pathway analysis of glioblastoma stem cells reveals potential novel biomarkers
Journal Articles

Abstract 2925: Protein pathway activation mapping of the NCI60 cell line series: Discovery of lineage-independent protein biomarkers for drug sensitivity/resistance prediction

Free
Giulia Federici, Valentina Fodale, Jianghong Deng, Ruggero De Maria, Lance A. Liotta, Emanuel F. Petricoin, Julia D. Wulfkuhle
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2925.
https://doi.org/10.1158/1538-7445.AM2011-2925
Published: 15 April 2011
View articletitled, Abstract 2925: Protein pathway activation mapping of the NCI60 cell line series: Discovery of lineage-independent protein biomarkers for drug sensitivity/resistance prediction
Journal Articles

Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells

Free
Matilde Todaro, Flora Iovino, Vincenzo Eterno, Patrizia Cammareri, Guido Gambara, Virginia Espina, Gaspare Gulotta, Francesco Dieli, Silvia Giordano, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8874–8885.
https://doi.org/10.1158/0008-5472.CAN-10-1994
Published: 31 October 2010
View articletitled, Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells
Open the PDF for Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells in another window
Includes: Supplementary data
Journal Articles

Suppressor of Cytokine Signaling 3 Sensitizes Anaplastic Thyroid Cancer to Standard Chemotherapy

Free
Maria Giovanna Francipane, Vincenzo Eterno, Valentina Spina, Miriam Bini, Gregorio Scerrino, Giuseppe Buscemi, Gaspare Gulotta, Matilde Todaro, Francesco Dieli, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6141–6148.
https://doi.org/10.1158/0008-5472.CAN-09-0994
Published: 29 July 2009
View articletitled, Suppressor of Cytokine Signaling 3 Sensitizes Anaplastic Thyroid Cancer to Standard Chemotherapy
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Journal Articles

Comparative cellular signal pathway analysis of metastatic colorectal cancer in human and preclinical animal model

Free
Noemi Moroni, Mariaelena Pierobon, Francesca Galdi, Claudio Belluco, Manuela Zonfrillo, Pasquale Pierimarchi, Annalucia Serafino, Donato Nitti, Enrico Garaci, Ruggero De Maria, Lance Liotta, Emanuel Petricoin, Guido Rasi
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5149.
Published: 01 May 2008
View articletitled, Comparative cellular signal pathway analysis of metastatic colorectal cancer in human and preclinical animal model
Journal Articles

Functional characterization of human cancer stem cells for targeted therapy

Free
Michele Signore, Dario Lombardi, Fiorenza Lotti, Lucia Ricci-Vitiani, Adriana Eramo, Lance Liotta, Emanuel Petricoin, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4617.
Published: 01 May 2008
View articletitled, Functional characterization of human cancer stem cells for targeted therapy
Journal Articles

MUC1 Oncoprotein Promotes Refractoriness to Chemotherapy in Thyroid Cancer Cells

Free
Mauro Siragusa, Monica Zerilli, Flora Iovino, Maria Giovanna Francipane, Ylenia Lombardo, Lucia Ricci-Vitiani, Giuseppe Di Gesù, Matilde Todaro, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2007) 67 (11): 5522–5530.
https://doi.org/10.1158/0008-5472.CAN-06-4197
Published: 01 June 2007
View articletitled, MUC1 Oncoprotein Promotes Refractoriness to Chemotherapy in Thyroid Cancer Cells
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Journal Articles

Chemotherapy-Induced Thrombocytopenia Derives from the Selective Death of Megakaryocyte Progenitors and Can Be Rescued by Stem Cell Factor

Free
Ann Zeuner, Michele Signore, Daniela Martinetti, Monica Bartucci, Cesare Peschle, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2007) 67 (10): 4767–4773.
https://doi.org/10.1158/0008-5472.CAN-06-4303
Published: 17 May 2007
View articletitled, Chemotherapy-Induced Thrombocytopenia Derives from the Selective Death of Megakaryocyte Progenitors and Can Be Rescued by Stem Cell Factor
Open the PDF for Chemotherapy-Induced Thrombocytopenia Derives from the Selective Death of Megakaryocyte Progenitors and Can Be Rescued by Stem Cell Factor in another window
Journal Articles

Autocrine Production of Interleukin-4 and Interleukin-10 Is Required for Survival and Growth of Thyroid Cancer Cells

Free
Matilde Todaro, Monica Zerilli, Lucia Ricci-Vitiani, Miriam Bini, Mileidys Perez Alea, Ada Maria Florena, Laura Miceli, Gerolama Condorelli, Sebastiano Bonventre, Giuseppe Di Gesù, Ruggero De Maria, Giorgio Stassi
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1491–1499.
https://doi.org/10.1158/0008-5472.CAN-05-2514
Published: 01 February 2006
View articletitled, Autocrine Production of Interleukin-4 and Interleukin-10 Is Required for Survival and Growth of Thyroid Cancer Cells
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Journal Articles

Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction

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Adriana Eramo, Roberto Pallini, Fiorenza Lotti, Giovanni Sette, Mariella Patti, Monica Bartucci, Lucia Ricci-Vitiani, Michele Signore, Giorgio Stassi, Luigi M. Larocca, Lucio Crinò, Cesare Peschle, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2005) 65 (24): 11469–11477.
https://doi.org/10.1158/0008-5472.CAN-05-1724
Published: 15 December 2005
View articletitled, Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction
Open the PDF for Inhibition of DNA Methylation Sensitizes Glioblastoma for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Mediated Destruction in another window
Journal Articles

Effective treatment of glioblastoma tumors by combined administration of decitabine and TRAIL

Free
Adriana Eramo, Roberto Pallini, Fiorenza Lotti, Giovanni Sette, Lucia Ricci-Vitiani, Monica Bartucci, Cesare Peschle, Ruggero De Maria
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 425.
Published: 01 May 2005
View articletitled, Effective treatment of glioblastoma tumors by combined administration of decitabine and TRAIL
Journal Articles

Inhibition of telomerase by RNA interference impairs the growth of glioblastoma tumor in vivo.

Free
Maria Laura Falchetti, Antonio Sorrentino, Ruggero De Maria, Nicola Maggiano, Luigi Maria Larocca, Francesco Pierconti, Giulio Maira, Roberto Pallini, Andrea Levi
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 558.
Published: 01 April 2004
View articletitled, Inhibition of telomerase by RNA interference impairs the growth of glioblastoma tumor in vivo.