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Journal Articles

Abstract 1722: Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer (NSCLC)

Miguel Lopez de Rodas Gregorio, Venkata Nagineni, Arvind Ravi, Ila J. Datar, Mari Mino-Kenudson, German Corredor, Cristian Barrera, Lindsey Behlman, David L. Rimm, Roy S. Herbst, Anant Madabhushi, Jonathan W. Riess, Vamsidhar Velcheti, Matthew Hellmann, Justin F. Gainor, Kurt A. Schalper

Cancer Res (2022) 82 (12_Supplement): 1722.

https://doi.org/10.1158/1538-7445.AM2022-1722

Published: 15 June 2022

View article titled, Abstract 1722: Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer (NSCLC)

Journal Articles

Abstract 2002: Assessment of the co-localization between PD-L1 positive macrophages and PD-1 positive cells is associated with benefit from PD-1 axis immunotherapy in NSCLC

Yuting Liu, Jon Zugazagoitia, Kurt A. Schalper, Roy S. Herbst, David L. Rimm

Cancer Res (2020) 80 (16_Supplement): 2002.

https://doi.org/10.1158/1538-7445.AM2020-2002

Published: 15 August 2020

View article titled, Abstract 2002: Assessment of the co-localization between PD-L1 positive macrophages and PD-1 positive cells is associated with benefit from PD-1 axis immunotherapy in NSCLC

Journal Articles

Abstract CT227: KEYNOTE-495/KeyImPaCT: Phase II biomarker-directed precision oncology study of pembrolizumab-based combination therapy for non-small cell lung cancer

Martin Gutierrez, Matthew D. Hellmann, Matthew Gubens, Charu Aggarwal, Daniel Shao Weng Tan, Enriqueta Felip, Joanne Wing Yan Chiu, Jong-Seok Lee, James Chih-Hsin Yang, Edward Garon, Andrea D. Basso, Hua Ma, Lawrence Fong, Alex Snyder, Jianda Yuan, Roy S. Herbst

Cancer Res (2019) 79 (13_Supplement): CT227.

https://doi.org/10.1158/1538-7445.AM2019-CT227

Published: 01 July 2019

View article titled, Abstract CT227: KEYNOTE-495/KeyImPaCT: Phase II biomarker-directed precision oncology study of pembrolizumab-based combination therapy for non-small cell lung cancer

Journal Articles

Abstract 3334: CREB is required for KRAS-driven lung tumorigenesis

Jong woo Lee, Frank J. Slack, Eric J. Nestler, Roy S. Herbst, Jaseok Peter Koo

Cancer Res (2018) 78 (13_Supplement): 3334.

https://doi.org/10.1158/1538-7445.AM2018-3334

Published: 01 July 2018

View article titled, Abstract 3334: CREB is required for <em>KRAS</em>-driven lung tumorigenesis

Journal Articles

Abstract 1681: Simultaneous measurement and significance of PD-1, LAG-3 and TIM-3 expression in human solid tumors

Micaela Morgado, Ila Datar, Jun Wang, Miguel F. Sanmamed, Kristen McEachern, David Jenkins, Lieping Chen, Daniel Carvajal-Hausdorf, David L. Rimm, Roy S. Herbst, Kurt A. Schalper

Cancer Res (2018) 78 (13_Supplement): 1681.

https://doi.org/10.1158/1538-7445.AM2018-1681

Published: 01 July 2018

View article titled, Abstract 1681: Simultaneous measurement and significance of PD-1, LAG-3 and TIM-3 expression in human solid tumors

Journal Articles

Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

Franz Villarroel-Espindola, Daniel Carvajal-Hausdorf, Ila Datar, Amanda Esch, Narges Rashidi, Ala Nassar, Shelly Ren, Ruth R. Montgomery, Roy S. Herbst, David L. Rimm, Kurt A. Schalper

Cancer Res (2017) 77 (13_Supplement): 1635.

https://doi.org/10.1158/1538-7445.AM2017-1635

Published: 01 July 2017

View article titled, Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

Journal Articles

Abstract 5657: Objective measurement and significance of VISTA (PD-1H) expression in non-small cell lung cancer (NSCLC)

Franz Villarroel-Espindola, Ila J. Datar, Vamsidhar Velcheti, David L. Rimm, Roy S. Herbst, Kurt A. Schalper

Cancer Res (2017) 77 (13_Supplement): 5657.

https://doi.org/10.1158/1538-7445.AM2017-5657

Published: 01 July 2017

View article titled, Abstract 5657: Objective measurement and significance of VISTA (PD-1H) expression in non-small cell lung cancer (NSCLC)

Journal Articles

Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases

Laura E. Stevens, William K.C. Cheung, Sally J. Adua, Anna Arnal-Estapé, Minghui Zhao, Zongzhi Liu, Kelly Brewer, Roy S. Herbst, Don X. Nguyen

Cancer Res (2017) 77 (8): 1905–1917.

https://doi.org/10.1158/0008-5472.CAN-16-1978

Published: 13 April 2017

View article titled, Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases

Includes: Supplementary data

Journal Articles

Abstract 89: Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma

Cancer Res (2016) 76 (14_Supplement): 89.

https://doi.org/10.1158/1538-7445.AM2016-89

Published: 15 July 2016

View article titled, Abstract 89: Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma

Journal Articles

Abstract 2334: Anti-cancer efficacy of the combination with immunomodulatory antibodies and MEK inhibitor for Kras mutation and p53 knockout driven lung cancer

Jong Woo Lee, Yu Zhang, Hee Sun Park, Sin Aye Park, JaSeok Peter Koo, Roy S. Herbst

Cancer Res (2016) 76 (14_Supplement): 2334.

https://doi.org/10.1158/1538-7445.AM2016-2334

Published: 15 July 2016

View article titled, Abstract 2334: Anti-cancer efficacy of the combination with immunomodulatory antibodies and MEK inhibitor for Kras mutation and p53 knockout driven lung cancer

Journal Articles

Abstract 1144: Detection of a novel ALK fusion variant in lung adenocarcinoma using a comprehensive genomic analysis

Kazuhiko Shien, Dennis Ruder, Ecaterina E. Ileana, Vassiliki A. Papadimitrakopoulou, Garrett M. Frampton, Carmen Behrens, Neda Kalhor, J. Jack Lee, Ximing Tang, Roy S. Herbst, Ignacio I. Wistuba, Julie G. Izzo

Cancer Res (2016) 76 (14_Supplement): 1144.

https://doi.org/10.1158/1538-7445.AM2016-1144

Published: 15 July 2016

View article titled, Abstract 1144: Detection of a novel ALK fusion variant in lung adenocarcinoma using a comprehensive genomic analysis

Journal Articles

Abstract 142: Mutation and immune profiles in early-stage lung squamous cell carcinoma

Cancer Res (2016) 76 (14_Supplement): 142.

https://doi.org/10.1158/1538-7445.AM2016-142

Published: 15 July 2016

View article titled, Abstract 142: Mutation and immune profiles in early-stage lung squamous cell carcinoma

Journal Articles

Abstract 745: Oncostatin M receptor activation leads to molecular targeted therapy resistance in non-small cell lung cancer

Kazuhiko Shien, Vassiliki A. Papadimitrakopoulou, Dennis Ruder, Nana E. Hanson, Neda Kalhor, J. Jack Lee, Waun Ki Hong, Ximing Tang, Roy S. Herbst, Luc Girard, John D. Minna, Jonathan M. Kurie, Ignacio I. Wistuba, Julie G. Izzo

Cancer Res (2015) 75 (15_Supplement): 745.

https://doi.org/10.1158/1538-7445.AM2015-745

Published: 01 August 2015

View article titled, Abstract 745: Oncostatin M receptor activation leads to molecular targeted therapy resistance in non-small cell lung cancer

Journal Articles

Abstract 2094: GSK-3 is a novel target of CREB and GSK-3-CREB signaling participates in cell survival in lung cancer

Sin-Aye Park, Jong Woo Lee, Roy S. Herbst, Jaseok Peter Koo

Cancer Res (2015) 75 (15_Supplement): 2094.

https://doi.org/10.1158/1538-7445.AM2015-2094

Published: 01 August 2015

View article titled, Abstract 2094: GSK-3 is a novel target of CREB and GSK-3-CREB signaling participates in cell survival in lung cancer

Journal Articles

Abstract 968: Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities

Cancer Res (2015) 75 (15_Supplement): 968.

https://doi.org/10.1158/1538-7445.AM2015-968

Published: 01 August 2015

View article titled, Abstract 968: Co-occurring genomic alterations define major subsets of <em>KRAS</em>-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities

Journal Articles

Abstract 3576: Rictor alterations elicit non-canonical signaling mechanisms contributing to tumorigenicity and therapeutic resistance in non-small cell lung cancer (NSCLC)

Dennis Ruder, Vassiliki Papadimitrakopoulou, Kazuhiko Shien, Neda Kalhor, J. Jack Lee, Waun K. Hong, Ximing Tang, Luc Girard, John D. Minna, Lixia Diao, Jing Wang, Nana E. Hanson, James Sun, Vincent Miller, Garrett Frampton, Roy S. Herbst, Ignacio I. Wistuba, Julie G. Izzo

Cancer Res (2015) 75 (15_Supplement): 3576.

https://doi.org/10.1158/1538-7445.AM2015-3576

Published: 01 August 2015

View article titled, Abstract 3576: Rictor alterations elicit non-canonical signaling mechanisms contributing to tumorigenicity and therapeutic resistance in non-small cell lung cancer (NSCLC)

Journal Articles

Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis

Bing Ma, Erica L. Herzog, Chun Geun Lee, Xueyan Peng, Chang-Min Lee, Xiaosong Chen, Sara Rockwell, Ja Seok Koo, Harriet Kluger, Roy S. Herbst, Mario Sznol, Jack A. Elias

Cancer Res (2015) 75 (3): 487–496.

https://doi.org/10.1158/0008-5472.CAN-13-3339

Published: 01 February 2015

View article titled, Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis

Includes: Supplementary data

Journal Articles

Abstract 985: The mutational landscape of LN metastasis and recurrence in HNSCC

Matthew Louis Hedberg, Gerald Goh, Maria Freilino, Yan Zeng, Vivian W. Lui, Roy S. Herbst, Richard P. Lifton, Jennifer R. Grandis

Cancer Res (2014) 74 (19_Supplement): 985.

https://doi.org/10.1158/1538-7445.AM2014-985

Published: 01 October 2014

View article titled, Abstract 985: The mutational landscape of LN metastasis and recurrence in HNSCC

Journal Articles

Abstract 4382: Genome-Wide Gene Expression analysis and molecular portraits regulated by NASEp, an inhibitor of CREB and CBP interaction, in non-small cell lung cancer.

Sin-Aye Park, James Platt, Hee Sun Park, Jong Woo Lee, David F. Stern, Roy S. Herbst, Jaseok Peter Koo

Cancer Res (2013) 73 (8_Supplement): 4382.

https://doi.org/10.1158/1538-7445.AM2013-4382

Published: 15 April 2013

View article titled, Abstract 4382: Genome-Wide Gene Expression analysis and molecular portraits regulated by NASEp, an inhibitor of CREB and CBP interaction, in non-small cell lung cancer.

Journal Articles

Abstract 3938: Role of Chi3l1/YKL-40 in the tumor progression and metastasis in the lung.

Chun Geun Lee, Bing Ma, Ja Seok Koo, Roy S. Herbst, Jack A. Elias

Cancer Res (2013) 73 (8_Supplement): 3938.

https://doi.org/10.1158/1538-7445.AM2013-3938

Published: 15 April 2013

View article titled, Abstract 3938: Role of Chi3l1/YKL-40 in the tumor progression and metastasis in the lung.

NARROW

Abstract 1722: Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer (NSCLC)

Abstract 2002: Assessment of the co-localization between PD-L1 positive macrophages and PD-1 positive cells is associated with benefit from PD-1 axis immunotherapy in NSCLC

Abstract CT227: KEYNOTE-495/KeyImPaCT: Phase II biomarker-directed precision oncology study of pembrolizumab-based combination therapy for non-small cell lung cancer

Abstract 3334: CREB is required for KRAS-driven lung tumorigenesis

Abstract 1681: Simultaneous measurement and significance of PD-1, LAG-3 and TIM-3 expression in human solid tumors

Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

Abstract 5657: Objective measurement and significance of VISTA (PD-1H) expression in non-small cell lung cancer (NSCLC)

Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases

Abstract 89: Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma

Abstract 2334: Anti-cancer efficacy of the combination with immunomodulatory antibodies and MEK inhibitor for Kras mutation and p53 knockout driven lung cancer

Abstract 1144: Detection of a novel ALK fusion variant in lung adenocarcinoma using a comprehensive genomic analysis

Abstract 142: Mutation and immune profiles in early-stage lung squamous cell carcinoma

Abstract 745: Oncostatin M receptor activation leads to molecular targeted therapy resistance in non-small cell lung cancer

Abstract 2094: GSK-3 is a novel target of CREB and GSK-3-CREB signaling participates in cell survival in lung cancer

Abstract 968: Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma (LUAC) with distinct biology and therapeutic vulnerabilities

Abstract 3576: Rictor alterations elicit non-canonical signaling mechanisms contributing to tumorigenicity and therapeutic resistance in non-small cell lung cancer (NSCLC)

Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis

Abstract 985: The mutational landscape of LN metastasis and recurrence in HNSCC

Abstract 4382: Genome-Wide Gene Expression analysis and molecular portraits regulated by NASEp, an inhibitor of CREB and CBP interaction, in non-small cell lung cancer.

Abstract 3938: Role of Chi3l1/YKL-40 in the tumor progression and metastasis in the lung.

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