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Journal Articles

Abstract 2998: Regulation of epidermal growth factor receptor signaling by BRCA1-microRNA 146a network

Easwari Kumaraswamy, Raeann M. Koren Shimak, Sumedha Gunewardena, Karen L. Wendt, Dani Alexander, Stacey L. Hembruff, Roy A. Jensen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2998.
https://doi.org/10.1158/1538-7445.AM2024-2998
Published: 22 March 2024
View articletitled, Abstract 2998: Regulation of epidermal growth factor receptor signaling by BRCA1-microRNA 146a network
Journal Articles

Abstract 1785: The role of BRCA1 on metabolic pathways in an in vivo system

Stacey L. Hembruff, Alexander Dekonenko, John Thyfault, Mihaela Sardiu, Michael Washburn, Roy A. Jensen, Lisa M. Harlan-Williams
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1785.
https://doi.org/10.1158/1538-7445.AM2024-1785
Published: 22 March 2024
View articletitled, Abstract 1785: The role of BRCA1 on metabolic pathways in an in vivo system
Journal Articles

Understanding and Overcoming Immunosuppression Shaped by Cancer Stem Cells

Linheng Li, Roy A. Jensen
Journal: Cancer Research
Cancer Res (2023) 83 (13): 2096–2104.
https://doi.org/10.1158/0008-5472.CAN-23-0230
Published: 05 July 2023
View articletitled, Understanding and Overcoming Immunosuppression Shaped by Cancer Stem Cells
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Journal Articles

Abstract P5-04-05: Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression

Aditya M. Vargheese, Ashley S. Cloud, Sumedha Gunewardena, Raeann M. Shimak, Sornakala Ganeshkumar, Easwari Kumaraswamy, Roy A. Jensen, Vargheese M. Chennathukuzhi
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P5-04-05.
https://doi.org/10.1158/1538-7445.SABCS21-P5-04-05
Published: 15 February 2022
View articletitled, Abstract P5-04-05: Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression
Journal Articles

Abstract 6405: Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting Notch signaling

Scott James Weir, Prasad Dandawate, Prabhu Ramamoorthy, Parthasarathy Ranjarajan, Robyn Wood, Amanda Brinker, Benjamin Woolbright, Mehmet Tanol, Tammy Ham, William McCulloch, Michael Dalton, Michael J. Baltezor, Roy A. Jensen, John A. Taylor, Shrikant Anant
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6405.
https://doi.org/10.1158/1538-7445.AM2020-6405
Published: 15 August 2020
View articletitled, Abstract 6405: Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting Notch signaling
Journal Articles

Abstract 4703: Role of REST in the regulation of MMP24 and estrogen sensitivity in breast cancer

Aditya M. Vargheese, Ashley Cloud, Sumedha Gunewardena, Raeann Shimak, Easwari Kumaraswamy, Roy A. Jensen, Vargheese M. Chennathukuzhi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4703.
https://doi.org/10.1158/1538-7445.AM2020-4703
Published: 15 August 2020
View articletitled, Abstract 4703: Role of REST in the regulation of MMP24 and estrogen sensitivity in breast cancer
Journal Articles

BRCA1—No Matter How You Splice It

Dan Li, Lisa M. Harlan-Williams, Easwari Kumaraswamy, Roy A. Jensen
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2091–2098.
https://doi.org/10.1158/0008-5472.CAN-18-3190
Published: 01 May 2019
View articletitled, BRCA1—No Matter How You Splice It
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Journal Articles

Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response

Prabhu Ramamoorthy, Sufi Mary Thomas, Gaurav Kaushik, Dharmalingam Subramaniam, Katherine M. Chastain, Animesh Dhar, Ossama Tawfik, Anup Kasi, Weijing Sun, Satish Ramalingam, Sumedha Gunewardena, Shahid Umar, Joshua M. Mammen, Subhash B. Padhye, Scott J. Weir, Roy A. Jensen, G. Sitta Sittampalam, Shrikant Anant
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1681–1695.
https://doi.org/10.1158/0008-5472.CAN-18-2602
Published: 01 April 2019
View articletitled, Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response
Open the PDF for Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response in another window
Includes: Supplementary data
Journal Articles

Abstract 5032: Tumor in a Dish (TiD): Novel approach for precision therapy using patient-derived cells

Prabhu Ramamoorthy, Sufi Thomas, Sathish Ramalingam, Gaurav Fnu, Sita G. Sittampalam, Roy A. Jensen, Shrikant Anant
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5032.
https://doi.org/10.1158/1538-7445.AM2018-5032
Published: 01 July 2018
View articletitled, Abstract 5032: Tumor in a Dish (TiD): Novel approach for precision therapy using patient-derived cells
Journal Articles

Abstract 5882: Bench-to-bedside translation of ciclopirox prodrug for the treatment of non-muscle invasive and muscle-invasive bladder cancer

Scott J. Weir, Partha Ranjarajan, Robyn Wood, Karl Schorno, Prabhu Ramamoorthy, Lian Rajweski, Kathy Heppert, Michael J. McKenna, William McCulloch, Greg A. Reed, Amanda Brinker, Michael J. Baltezor, Roy A. Jensen, John A. Taylor, Shrikant Anant
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5882.
https://doi.org/10.1158/1538-7445.AM2018-5882
Published: 01 July 2018
View articletitled, Abstract 5882: Bench-to-bedside translation of ciclopirox prodrug for the treatment of non-muscle invasive and muscle-invasive bladder cancer
Journal Articles

Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver–Dependent Manner

Amanda E. Brinker, Carolyn J. Vivian, Devin C. Koestler, Trevor T. Tsue, Roy A. Jensen, Danny R. Welch
Journal: Cancer Research
Cancer Res (2017) 77 (24): 6941–6949.
https://doi.org/10.1158/0008-5472.CAN-17-2194
Published: 14 December 2017
View articletitled, Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver–Dependent Manner
Open the PDF for Mitochondrial Haplotype Alters Mammary Cancer Tumorigenicity and Metastasis in an Oncogenic Driver–Dependent Manner in another window
Includes: Supplementary data
Journal Articles

Abstract 3227: Novel Marmelin analog DBQ targets Notch signaling pathway in colon cancer stem cells

Dharmalingam Subramaniam, Sivapriya Ponnurangam, Prasad R. Dandawate, Gaurav Kaushik, Ossama W. Tawfik, Roy A. Jensen, Santimukul Santra, Subhash B. Padhye, Scott J. Weir, Shrikant Anant
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3227.
https://doi.org/10.1158/1538-7445.AM2017-3227
Published: 01 July 2017
View articletitled, Abstract 3227: Novel Marmelin analog DBQ targets Notch signaling pathway in colon cancer stem cells
Journal Articles

Abstract 1310: Targetingprolactin signaling to suppress pancreatic cancer stem cells

Prasad Dandawate, Gaurav Kaushik, Dharmalingam Subramaniam, Prabhu Ramamoorthy, Scott J. Weir, Roy A. Jensen, Shrikant Anant
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1310.
https://doi.org/10.1158/1538-7445.AM2016-1310
Published: 15 July 2016
View articletitled, Abstract 1310: Targetingprolactin signaling to suppress pancreatic cancer stem cells
Journal Articles

Abstract 1727: Quinomycin A inhibits pancreatic cancer growth and affects stem cell viability by inhibiting oncogenic YAP1 function

Dharmalingam Subramaniam, Sivapriya Ponnurangam, Gaurav Fnu, Prabhu Ramamoorthy, Animesh Dhar, Ossama W. Tawfik, Shahid Umar, Scott J. Weir, Roy A. Jensen, Arun Balakrishnan, Shrikant Anant
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1727.
https://doi.org/10.1158/1538-7445.AM2016-1727
Published: 15 July 2016
View articletitled, Abstract 1727: Quinomycin A inhibits pancreatic cancer growth and affects stem cell viability by inhibiting oncogenic YAP1 function
Journal Articles

Abstract 4632: Effects of Hsp90 inhibitors on triple-negative breast cancer: BRCA1 as a therapeutic target for TNBC

Prabhu Ramamoorthy, Parthasarathy Rangarajan, Ossama Tawfik, Shrikant Anant, Roy A. Jensen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4632.
https://doi.org/10.1158/1538-7445.AM2016-4632
Published: 15 July 2016
View articletitled, Abstract 4632: Effects of Hsp90 inhibitors on triple-negative breast cancer: BRCA1 as a therapeutic target for TNBC
Journal Articles

Abstract 4748: Targeting colon cancer stem cells: Novel marmelin analog THB suppresses DCLK1 and Notch Signaling

Dharmalingam Subramaniam, Sivapriya Ponnurangam, Prasad R. Dandawate, Ossama W. Tawfik, Roy A. Jensen, Scott J. Weir, Subhash B. Padhye, Shrikant Anant
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4748.
https://doi.org/10.1158/1538-7445.AM2016-4748
Published: 15 July 2016
View articletitled, Abstract 4748: Targeting colon cancer stem cells: Novel marmelin analog THB suppresses DCLK1 and Notch Signaling
Journal Articles

Essential Components of Cancer Education

Danny R. Welch, Toni M. Antalis, Kerry Burnstein, Linda Vona-Davis, Roy A. Jensen, Harikrishna Nakshatri, Anna T. Riegel, Douglas R. Spitz, Dennis K. Watson, George J. Weiner
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5202–5205.
https://doi.org/10.1158/0008-5472.CAN-15-2077
Published: 14 December 2015
View articletitled, Essential Components of Cancer Education
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Journal Articles

Abstract 4214: Quinomycin A affects pancreatic cancer stem cells in part through suppression of notch signaling pathway

Dharmalingam Subramaniam, Sivapriya Ponnurangam, Afreen Sayed, Animesh Dhar, Dan A. Dixon, Ossama Tawfik, Rajashri R. Parab, Prabhu Dutt Mishra, Prafull Ranadive, Rajiv Sharma, Girish Mahajan, Aravind Sugumar, Scott J. Weir, Roy A. Jensen, Arun Balakrishnan, Shrikant Anant
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4214.
https://doi.org/10.1158/1538-7445.AM2015-4214
Published: 01 August 2015
View articletitled, Abstract 4214: Quinomycin A affects pancreatic cancer stem cells in part through suppression of notch signaling pathway
Journal Articles

Abstract 1893: Honokiol prevents colonic tumorigenesis and affects stem cell viability by affecting oncogenic YAP1 function

Dharmalingam Subramaniam, Sivapriya Ponnurangam, Deep Kwatra, Gaurav Kaushik, Prabhu Ramamoorthy, Satish Ramalingam, Ossama Tawfik, Scott J. Weir, Subhash Padhye, Dan A. Dixon, Shahid Umar, Roy A. Jensen, Shrikant Anant
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1893.
https://doi.org/10.1158/1538-7445.AM2015-1893
Published: 01 August 2015
View articletitled, Abstract 1893: Honokiol prevents colonic tumorigenesis and affects stem cell viability by affecting oncogenic YAP1 function
Journal Articles

Abstract P3-06-16: Thrombocytopenia is associated with pathological complete response to neoadjuvant carboplatin/docetaxel chemotherapy in BRCA wild type triple negative breast cancer

Priyanka Sharma, Benjamin C Powers, Bruce F Kimler, Claire Ward, Jennifer R Klemp, Carol S Connor, Marilee K McGinness, Joshua MV Mammen, Jamie L Wagner, Qamar J Khan, Roy A Jensen, Andrew K Godwin, Carol J Fabian
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-06-16.
https://doi.org/10.1158/1538-7445.SABCS14-P3-06-16
Published: 01 May 2015
View articletitled, Abstract P3-06-16: Thrombocytopenia is associated with pathological complete response to neoadjuvant carboplatin/docetaxel chemotherapy in BRCA wild type triple negative breast cancer