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Rosalba Minelli
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Journal Articles

Abstract 5972: Therapeutic modulation of rock overcomes metabolic adaption to oxphos inhibition and suppresses tumor growth

Nicholas Blazanin, Xiaobing Liang, Iqbal Mahmud, Eiru Kim, Lin Tan, Nazanin Esmaeili Anvar, Waikin Chan, Min Jin Ha, Rosalba Minelli, Michael Peoples, Philip Lorenzi, Travar Hart, Yonathan Lissanu, Nicholas Blazanin
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5972.
https://doi.org/10.1158/1538-7445.AM2024-5972
Published: 22 March 2024
View article titled, Abstract 5972: Therapeutic modulation of rock overcomes metabolic adaption to oxphos inhibition and suppresses tumor growth
Journal Articles

Abstract 1447: Development of advanced preclinical modeling for a comprehensive characterization of cardiac angiosarcoma biology

Rosalba Minelli, Luigi Perelli, Benjamin J. Bivona, Sanjana Srinivasan, Desiree Catania, Bianca E. Amador, Frederick S. Robinson, Johnathon L. Rose, Christopher T. Terranova, Alejandro Hernandez Martinez, Charles E. Deckard, Courtney N. Le, Kuo-Shun Hsu, Michael Peoples, Aparna Subramaniam, Hannah C. Beird, Ningping Feng, Joseph R. Daniele, Christopher Vellano, Joseph Marszalek, Vinod Ravi, Alexander J. Lazar, Andrew Futreal, Timothy P. Heffernan, Giannicola Genovese, Virginia Giuliani
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1447.
https://doi.org/10.1158/1538-7445.AM2024-1447
Published: 22 March 2024
View article titled, Abstract 1447: Development of advanced preclinical modeling for a comprehensive characterization of cardiac angiosarcoma biology
Journal Articles

Abstract 1758: Chromosome 3 copy number loss alone drives tumor evolution to aggressive disease in uveal melanoma

Sanjana Srinivasan, Johnathon Rose, Rosalba Minelli, Christopher Terranova, Parth Shah, Joseph R. Daniele, Michael Peoples, Meng He, Chiu-Yi Liu, Jason Gay, Melinda Soeung, Sanjay Soni, Fangyang Wang, Christopher Bristow, Khalida Wani, Luigi Perelli, Dmitry Loza, Ningping Feng, Maxime Tarabichi, Peter Van Loo, Andrew Futreal, Scott Woodman, Alexander Lazar, Christopher P. Vellano, Joseph Marszalek, Giulio F. Draetta, Timothy Heffernan, Alessandro Carugo, Giannicola Genovese, Virginia Giuliani
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1758.
https://doi.org/10.1158/1538-7445.AM2024-1758
Published: 22 March 2024
View article titled, Abstract 1758: Chromosome 3 copy number loss alone drives tumor evolution to aggressive disease in uveal melanoma
Journal Articles

Abstract 4304: Chromosome 3 dosage-loss informs on the unique biology underlying ultra high-risk uveal melanoma

Johnathon Lynn Rose, Sanjana Srinivasan, Meng He, Rosalba Minelli, Chiu-Yi Liu, Christopher Terranova, Jason Gay, Joseph R. Daniele, Loza Dmitriy, Michael Peoples, Melinda Soeung, Vandhana Ramamoorthy, Parth Shah, Sanjay Soni, Christopher Bristow, Fangyang Wang, Anastasia Lopez, Charles Deckard, Brooke Meyers, Luigi Perelli, Khalida Wani, Ningping Feng, Christopher P. Vellano, Joe Marszalek, Alexander J. Lazar, Andrew Futreal, Giulio F. Draetta, Scott E. Woodman, Timothy Heffernan, Giannicola Genovese, Alessandro Carugo, Virginia Giuliani
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4304.
https://doi.org/10.1158/1538-7445.AM2024-4304
Published: 22 March 2024
View article titled, Abstract 4304: Chromosome 3 dosage-loss informs on the unique biology underlying ultra high-risk uveal melanoma
Journal Articles

Abstract 3280: ASCL2+ tumor cells modulate the response of colorectal cancer to MAPK targeting therapy

Oscar E. Villarreal, Hey Min Lee, Ha Tran, Annette Machado, Jumanah Alshenaifi, Chi Wut Wong, Olu Coker, Rosalba Minelli, Michael Peoples, Alejandro Hernandez Martinez, Natalie Fowlkes, Preeti Kanikarla, Kangyu Lin, Christopher Bristow, Andrea Viale, Joseph R. Marszalek, John Paul Shen, Scott Kopetz
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3280.
https://doi.org/10.1158/1538-7445.AM2024-3280
Published: 22 March 2024
View article titled, Abstract 3280: ASCL2<sup>+</sup> tumor cells modulate the response of colorectal cancer to MAPK targeting therapy
Journal Articles

Abstract 94: Advanced preclinical modeling reveals unique monosomy 3 associated biology in late-stage uveal melanoma

Johnathon L. Rose, Sanjana Srinivasan, Meng He, Rosalba Minelli, Chiu-Yi Liu, Jason Gay, Joseph R. Daniele, Michael Peoples, Melinda Soeung, Vandhana Ramamoorthy, Anastasia Lopez, Charles Deckard, Brooke Meyers, Edoardo Del Poggetto, Daniel Zamler, Justin Huang, Luigi Perelli, Khalida Wani, Christopher Bristow, Ningping Feng, Christopher P. Vellano, Joe Marszalek, Alexander J. Lazar, Andrew Futreal, Giulio F. Draetta, Scott E. Woodman, Timothy Heffernan, Giannicola Genovese, Alessandro Carugo, Virginia Giuliani
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 94.
https://doi.org/10.1158/1538-7445.AM2023-94
Published: 04 April 2023
View article titled, Abstract 94: Advanced preclinical modeling reveals unique monosomy 3 associated biology in late-stage uveal melanoma
Journal Articles

Abstract 92: Deploying spatial transcriptomics to inform intratumoral heterogeneity in late-stage uveal melanoma leveraging advanced preclinical modeling and clinical samples

Sanjana Srinivasan, Johnathon Rose, Joseph R. Daniele, Michael Peoples, Meng He, Rosalba Minelli, Chiu-Yi Liu, Jason Gay, Melinda Soeung, Khalida Wani, Luigi Perelli, Dmitriy Loza, Ningping Feng, Christopher P. Vellano, Joseph Marszalek, Giulio F. Draetta, P. Andrew Futreal, Scott E. Woodman, Alexander J. Lazar, Timothy Heffernan, Alessandro Carugo, Giannicola Genovese, Virginia Giuliani
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 92.
https://doi.org/10.1158/1538-7445.AM2023-92
Published: 04 April 2023
View article titled, Abstract 92: Deploying spatial transcriptomics to inform intratumoral heterogeneity in late-stage uveal melanoma leveraging advanced preclinical modeling and clinical samples
Journal Articles

Abstract LB079: Pancreatic clonal replica tumors display functional heterogeneity in response to KRAS pharmacological inhibition and reveal unique epigenetic vulnerabilities to overcome resistance

Hengyu Lyu, Rosalba Minelli, Charles E. Deckard, Sahil Seth, Justin Huang, Hong Jiang, Michael D. Peoples, Meggie Lam, Christopher A. Bristow, Daniel Gerlach, Ulrike Tontsch-Grunt, Chieh-Yuan Li, I-Lin Ho, Christopher P. Vellano, Marco H. Hofmann, Timothy P. Heffernan, Joseph R. Marszalek, Andrea Viale, Alessandro Carugo
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB079.
https://doi.org/10.1158/1538-7445.AM2022-LB079
Published: 15 June 2022
View article titled, Abstract LB079: Pancreatic clonal replica tumors display functional heterogeneity in response to KRAS pharmacological inhibition and reveal unique epigenetic vulnerabilities to overcome resistance
Journal Articles

Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis

Nakia D. Spencer, Christopher A. Bristow, Virginia Giulani, Meredith A. Miller, Alessandro Carugo, Angela L. Harris, Rosalba Minelli, Ningpeng Feng, Qing Chang, Michael J. Soth, Kang Le, John N. Weinstein, Philip L. Lorenzi, Jinsong Liu, Wei-Lien Wang, Timothy A. Yap, Giulio Draetta, Philip Jones, Timothy P. Heffernan, Jeffrey J. Kovacs
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 87.
https://doi.org/10.1158/1538-7445.AM2021-87
Published: 01 July 2021
View article titled, Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis
Journal Articles

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma

Carla Mottini, Hideo Tomihara, Diego Carrella, Alessia Lamolinara, Manuela Iezzi, Justin K. Huang, Carla A. Amoreo, Simonetta Buglioni, Isabella Manni, Frederick S. Robinson, Rosalba Minelli, Ya'an Kang, Jason B. Fleming, Michael P. Kim, Christopher A. Bristow, Daniela Trisciuoglio, Antonella Iuliano, Donatella Del Bufalo, Diego Di Bernardo, Davide Melisi, Giulio F. Draetta, Gennaro Ciliberto, Alessandro Carugo, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5612–5625.
https://doi.org/10.1158/0008-5472.CAN-19-0187
Published: 01 November 2019
View article titled, Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma
Open the PDF for Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract B40: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors

Melinda Soeung, Alessandro Carugo, Frederick Scott Robinson, Rosalba Minelli, Federica Carbone, Anirban Maitra, Andrea Viale, Charles W.M. Roberts, Nizar Tannir, Giulio F. Draetta, Giannicola Genovese
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): B40.
https://doi.org/10.1158/1538-7445.PEDCA17-B40
Published: 01 October 2018
View article titled, Abstract B40: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors
Journal Articles

Abstract A03: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors

Giannicola Genovese, Alessandro Carugo, Rosalba Minelli, Frederick, Scott Robinson, Pavlos Msaouel, Tim Heffernan, Andrea Viale, Nizar Tannir, Giulio Draetta
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A03.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A03
Published: 14 May 2018
View article titled, Abstract A03: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors
Journal Articles

Abstract 955: High-throughput functional screening for metastasis drivers of lung cancer

Caitlin L. Grzeskowiak, Rosalba Minelli, Ping Wu, Samrat Kundu, Don L. Gibbons, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 955.
https://doi.org/10.1158/1538-7445.AM2015-955
Published: 01 August 2015
View article titled, Abstract 955: High-throughput functional screening for metastasis drivers of lung cancer
Journal Articles

Abstract B106: Personalized functional screens for gene drivers of pancreatic cancer

Yiu Huen Tsang, Turgut Dogruluk, Hengyu Lu, Rosalba Minelli, Nikitha Nair, Marie-Claude Gingras, Agda Karina Eterovic, Gordon Mills, Kenneth Scott
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B106.
https://doi.org/10.1158/1538-7445.PANCA2014-B106
Published: 30 June 2015
View article titled, Abstract B106: Personalized functional screens for gene drivers of pancreatic cancer
Journal Articles

Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer

Piergiorgio Pettazzoni, Andrea Viale, Parantu Shah, Alessandro Carugo, Haoqiang Ying, Huamin Wang, Giannicola Genovese, Sahil Seth, Rosalba Minelli, Tessa Green, Emmet Huang-Hobbs, Denise Corti, Nora Sanchez, Luigi Nezi, Matteo Marchesini, Avnish Kapoor, Wantong Yao, Maria E. Di Francesco, Alessia Petrocchi, Angela K. Deem, Kenneth Scott, Simona Colla, Gordon B. Mills, Jason B. Fleming, Timothy P. Heffernan, Philip Jones, Carlo Toniatti, Ronald A. DePinho, Giulio F. Draetta
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (6): 1091–1101.
https://doi.org/10.1158/0008-5472.CAN-14-1854
Published: 12 March 2015
View article titled, Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer
Open the PDF for Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract C10: High-throughput functional annotation of somatic driver aberrations in cancer

Turgut Dogruluk, Armel Dogruluk, Yiu-Huen Tsang, Nikitha Nair, Rosalba Minelli, Ping Wu, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C10.
https://doi.org/10.1158/1538-7445.FBCR13-C10
Published: 15 May 2014
View article titled, Abstract C10: High-throughput functional annotation of somatic driver aberrations in cancer
Journal Articles

Abstract 4431: Antitumor activity of nanosponge-encapsulated camptotechin in human prostate tumors

Rosalba Minelli, Roberta Cavalli, Roberto Fantozzi, Chiara Dianzani, Piergiorgio Pettazzoni, Leigh Ellis, Li Shen, Roberto Pili
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4431.
https://doi.org/10.1158/1538-7445.AM2011-4431
Published: 15 April 2011
View article titled, Abstract 4431: Antitumor activity of nanosponge-encapsulated camptotechin in human prostate tumors