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Journal Articles

Abstract B027: Spatial transcriptomic profiling of the head and neck cancer tumor microenvironment to guide design of microphysiological systems for reporting treatment response

Rene Welch Schwartz, Adeel Ahmed, Rong Hu, Randall J Kimple, Paul M Harari, Irene M Ong, Sheena C Kerr
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): B027.
https://doi.org/10.1158/1538-7445.GENFUNC25-B027
Published: 11 March 2025
View article titled, Abstract B027: Spatial transcriptomic profiling of the head and neck cancer tumor microenvironment to guide design of microphysiological systems for reporting treatment response
Journal Articles

Abstract 3078: YIV-818-A enhanced apalutamide, darolutamide and enzalutamide action for prostate cancer treatment by down-regulating androgen receptor protein, inhibiting glucocorticoid receptor function and epigenetic regulation

Wing Lam, Mohammad Arammash, Wei Cai, Rong Hu, Shwu-Huey Liu, Peikwen Cheng, Yung-chi Cheng
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3078.
https://doi.org/10.1158/1538-7445.AM2023-3078
Published: 04 April 2023
View article titled, Abstract 3078: YIV-818-A enhanced apalutamide, darolutamide and enzalutamide action for prostate cancer treatment by down-regulating androgen receptor protein, inhibiting glucocorticoid receptor function and epigenetic regulation
Journal Articles

Abstract 3003: The effects of autophagy inhibition on HNSCC sensitivity to CTX

Samantha T. Bradley, Yong-Syu Lee, Justin H. Skiba, Jaimee Eckers, Adam D. Swick, Rong Hu, Kwang P. Nickel, Zafer Gurel, Pippa F. Cosper, Randall J. Kimple
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3003.
https://doi.org/10.1158/1538-7445.AM2022-3003
Published: 15 June 2022
View article titled, Abstract 3003: The effects of autophagy inhibition on HNSCC sensitivity to CTX
Journal Articles

Abstract B19: Role of cell-cell communication in endocrine therapy-resistant breast cancer

Surojeet Sengupta, Rong Hu, Zachary Susswein, Adeola Fagunloye, Shweta Bansal, Robert Clarke
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): B19.
https://doi.org/10.1158/1538-7445.CAMODELS2020-B19
Published: 02 June 2020
View article titled, Abstract B19: Role of cell-cell communication in endocrine therapy-resistant breast cancer
Journal Articles

Abstract 2252: YIV-906 (PHY906) enhanced the anti-tumor activity of immune checkpoint blockade therapy (Anti-PD1) against liver cancer by changing the tumor micro-environment associated with M1 macrophages infiltration

Wing Lam, Xiaochen Yang, Zaoli Jiang, Xue han, Fulan Guan, Rong Hu, Chang-Hua Xu, Wei Cai, William Cheng, Shwu-Huey Liu, Yuping Cai, Nicholas Rattray, Caroline Johnson, Lieping Chen, Yung-chi Cheng
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2252.
https://doi.org/10.1158/1538-7445.AM2019-2252
Published: 01 July 2019
View article titled, Abstract 2252: YIV-906 (PHY906) enhanced the anti-tumor activity of immune checkpoint blockade therapy (Anti-PD1) against liver cancer by changing the tumor micro-environment associated with M1 macrophages infiltration
Journal Articles

Abstract 2179: Population remodeling in the acquisition of endocrine resistance in breast cancer

Rong Hu, Surojeet Sengupta, Catherine Sevigny, Zhen Zhang, Yue Wang, Robert Clarke
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2179.
https://doi.org/10.1158/1538-7445.AM2018-2179
Published: 01 July 2018
View article titled, Abstract 2179: Population remodeling in the acquisition of endocrine resistance in breast cancer
Journal Articles

Abstract 2164: BLID is a novel drug-inducible apoptotic molecule: Identification of an integrative mechanism of chemosensitivity in breast cancer cells

Sivaramakrishna Yadavalli, Rong Hu, Antonina Rait, Xin Li, Esther Chang, Robert Clarke, Usha Kasid
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2164.
https://doi.org/10.1158/1538-7445.AM2017-2164
Published: 01 July 2017
View article titled, Abstract 2164: BLID is a novel drug-inducible apoptotic molecule: Identification of an integrative mechanism of chemosensitivity in breast cancer cells
Journal Articles

Abstract 5187: Potent radiosensitization of adenoid cystic carcinoma in a patient derived xenograft model using the MDM2 inhibitor AMG 232

Amal Javaid, Adam D. Swick, Lauryn Werner, Prashanth Prabakaran, Rong Hu, Kwangok P. Nickel, Irene Ong, Emmanuel Sampene, Justine Bruce, Gregory Hartig, Aaron Wieland, Jude Canon, Paul Harari, Randall Kimple
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5187.
https://doi.org/10.1158/1538-7445.AM2017-5187
Published: 01 July 2017
View article titled, Abstract 5187: Potent radiosensitization of adenoid cystic carcinoma in a patient derived xenograft model using the MDM2 inhibitor AMG 232
Journal Articles

Abstract 2329: TMEM33 induces apoptosis via UPR signaling and autophagy in breast cancer cells

Rong Hu, Xiyuan Zhang, Leena Hilakivi-Clarke, Usha Kasid, Robert Clarke
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2329.
https://doi.org/10.1158/1538-7445.AM2017-2329
Published: 01 July 2017
View article titled, Abstract 2329: TMEM33 induces apoptosis via UPR signaling and autophagy in breast cancer cells
Journal Articles

Abstract 4947: Branched chain RNA in situ hybridization for the detection of androgen receptor splice variants within archival prostate cancer tissue

Philip J. Saylor, Richard J. Lee, Kshitij S. Arora, David T. Ting, Vikram Deshpande, Miguel N. Rivera, Rong Hu, Chin-Lee Wu, David T. Miyamoto
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4947.
https://doi.org/10.1158/1538-7445.AM2016-4947
Published: 15 July 2016
View article titled, Abstract 4947: Branched chain RNA <em>in situ</em> hybridization for the detection of androgen receptor splice variants within archival prostate cancer tissue
Journal Articles

Abstract 1027: Autophagy as a mediator of increased mammary cancer risk in socially isolated mice

Leena A. Hilakivi-Clarke, Fabia O. Andrade, Allison Sumis, Kerrie B. Bouker, Rong Hu, Robert Clarke, Katherine L. Cook
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1027.
https://doi.org/10.1158/1538-7445.AM2016-1027
Published: 15 July 2016
View article titled, Abstract 1027: Autophagy as a mediator of increased mammary cancer risk in socially isolated mice
Journal Articles

The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women

Sung Jin Huh, Hannah Oh, Michael A. Peterson, Vanessa Almendro, Rong Hu, Michaela Bowden, Rosina L. Lis, Maura B. Cotter, Massimo Loda, William T. Barry, Kornelia Polyak, Rulla M. Tamimi
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1926–1934.
https://doi.org/10.1158/0008-5472.CAN-15-1927
Published: 31 March 2016
View article titled, The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women
Open the PDF for The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women in another window
Includes: Supplementary data
Journal Articles

Abstract P6-05-01: Endoplasmic reticulum resident protein transmembrane protein 33 (TMEM33) induces apoptosis via UPR signaling and autophagy in breast cancer cells

Rong Hu, Xiyuan Zhang, Leena Hilakivi-Clarke, Usha Kasid, Robert Clarke
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-05-01.
https://doi.org/10.1158/1538-7445.SABCS14-P6-05-01
Published: 01 May 2015
View article titled, Abstract P6-05-01: Endoplasmic reticulum resident protein transmembrane protein 33 (TMEM33) induces apoptosis via UPR signaling and autophagy in breast cancer cells
Journal Articles

Abstract C45: Inhibition of antiapoptotic BCL2 members facilitates interferon regulatory factor-1 (IRF1) mediated prodeath signaling in breast cancer cells

Jessica L. Schwartz, Rong Hu, Ayesha N. Shajahan, Robert Clarke
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): C45.
https://doi.org/10.1158/1538-7445.FBCR11-C45
Published: 28 October 2014
View article titled, Abstract C45: Inhibition of antiapoptotic BCL2 members facilitates interferon regulatory factor-1 (IRF1) mediated prodeath signaling in breast cancer cells
Journal Articles

Abstract 3269: QTLs in breast tumor and breast normal adjacent FFPE specimens from the Nurses’ Health Study

Alejandro Quiroz-Zarate, Benjamin J. Harshfield, Rong Hu, Nick Knoblauch, Andrew H. Beck, Vincent Carey, Susan E. Hankinson, Rulla M. Tamimi, David J. Hunter, John Quackenbush, Aditi Hazra
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3269.
https://doi.org/10.1158/1538-7445.AM2014-3269
Published: 01 October 2014
View article titled, Abstract 3269: QTLs in breast tumor and breast normal adjacent FFPE specimens from the Nurses’ Health Study
Journal Articles

Abstract IA21: Transcriptional programs directed by the androgen receptor splice variants

Rong Hu, Changxue Lu, Elahe A. Mostaghel, Srinivasan Yegnasubramanian, Meltem Gurel, Clare Tannahill, Joanne Edwards, William Isaacs, Peter S. Nelson, Eric Bluemn, Stephen R. Plymate, Jun Luo
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): IA21.
https://doi.org/10.1158/1538-7445.PRCA2012-IA21
Published: 09 May 2013
View article titled, Abstract IA21: Transcriptional programs directed by the androgen receptor splice variants
Journal Articles

Abstract LB-254: XBP1-NFkappaB signaling promotes antiestrogen resistance in breast cancer animal model.

Rong Hu, Alan Zwart, Anni Warri, Robert Clarke
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-254.
https://doi.org/10.1158/1538-7445.AM2013-LB-254
Published: 15 April 2013
View article titled, Abstract LB-254: XBP1-NFkappaB signaling promotes antiestrogen resistance in breast cancer animal model.
Journal Articles

Abstract 4046: Estrogen receptor-α coordinates the unfolded protein response,autophagy, and reactive oxygen species generation to regulate breast cancer survival.

Pamela A. Clarke, Katherine Cook, Rong Hu, Jessica L. Schwartz, Mones Abu-Asab, Anni Warri, Robert Clarke
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4046.
https://doi.org/10.1158/1538-7445.AM2013-4046
Published: 15 April 2013
View article titled, Abstract 4046: Estrogen receptor-α coordinates the unfolded protein response,autophagy, and reactive oxygen species generation to regulate breast cancer survival.
Journal Articles

Abstract 1667: Autophagy and unfolded protein response (UPR) signaling regulates progression of apoptosis in mammary gland involution.

Katherine L. Cook, Anni Warri, Rong Hu, Lu Jin, Alan Zwart, David R. Soto Pantoja, Jie Liu, Toren Finkel, Robert Clarke
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1667.
https://doi.org/10.1158/1538-7445.AM2013-1667
Published: 15 April 2013
View article titled, Abstract 1667: Autophagy and unfolded protein response (UPR) signaling regulates progression of apoptosis in mammary gland involution.
Journal Articles

Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

Rong Hu, Changxue Lu, Elahe A. Mostaghel, Srinivasan Yegnasubramanian, Meltem Gurel, Clare Tannahill, Joanne Edwards, William B. Isaacs, Peter S. Nelson, Eric Bluemn, Stephen R. Plymate, Jun Luo
Journal: Cancer Research
Cancer Res (2012) 72 (14): 3457–3462.
https://doi.org/10.1158/0008-5472.CAN-11-3892
Published: 15 July 2012
View article titled, Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
Open the PDF for Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data