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Ronan Chaligne
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Journal Articles

Abstract A007: Emergence of metastasis-initiating cells during lung adenocarcinoma progression

Free
Jin Suk Park, Yasemin Kaygusuz, Carson Kenum, Mohamed I. Gatie, Lan He, Roshan Sharma, Ronan Chaligné, Abdul G. Khan, Ivo C. Lorenz, Paul J. Balderes, Tuomas Tammela, Anna-Katerina Hadjantonakis, Karuna Ganesh, Charles M. Rudin, Joan Massagué
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): A007.
https://doi.org/10.1158/1538-7445.TUMBODY-A007
Published: 17 November 2024
View articletitled, Abstract A007: Emergence of metastasis-initiating cells during lung adenocarcinoma progression
Journal Articles

Abstract C006: Tumor-associated macrophages drive prostate cancer progression via IL-1β signaling

Free
Young Sun Lee, Jimmy L. Zhao, Max Land, Joseph Chan, Perianne Smith, Roshan Sharma, Sanjay Kottapalli, Linda Fong, Zhenghao Chen, Cathy Wang, Jesse Kirkpatrick, Ava Soleimany, Samir Zaidi, Kayla Lawrence, Amanda Kulick, Teng Han, Zhen Sun, Philip Watson, Anuradha Gopalan, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Ronan Chaligne, Dana Rathkopf, Michael Morris, Sangeeta Bhatia, Michael Haffner, Dana Pe'er, Charles Sawyers
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C006.
https://doi.org/10.1158/1538-7445.TUMBODY-C006
Published: 17 November 2024
View articletitled, Abstract C006: Tumor-associated macrophages drive prostate cancer progression via IL-1β signaling
Journal Articles

Abstract 6626: Functional and molecular interrogation of a high-plasticity cell state in lung cancer

Free
Jason Earl Chan, Chun-Hao Pan, Carleigh Sussman, Hannah Styers, Emma Brown, Griffin Hartmann, Brigita Meškauskaitė, Melissa Blum, Selena Ding, Stefan Torborg, Zhuxuan Li, Simon Joost, Eliud Rivas-Hernandez, Thomas Norman, Ronan Chaligne, Yan Yan, Tuomas Tammela
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6626.
https://doi.org/10.1158/1538-7445.AM2024-6626
Published: 22 March 2024
View articletitled, Abstract 6626: Functional and molecular interrogation of a high-plasticity cell state in lung cancer
Journal Articles

Abstract 6840: Automated preparation of single nuclei from FFPE samples for snRNA-Seq

Free
Stevan Jovanovich, Nate Pereira, Danielle Meyer, Catherine Snopkowski, Ignas Masilionis, Brigita Meškauskaitė, Meril Takizawa, Zaki Abou-Mrad, Kenny Yu, Viviane Tabar, Kathleen Luckett, Karuna Ganesh, Nabiha Khan, Ronan Chaligne
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6840.
https://doi.org/10.1158/1538-7445.AM2024-6840
Published: 22 March 2024
View articletitled, Abstract 6840: Automated preparation of single nuclei from FFPE samples for snRNA-Seq
Journal Articles

Abstract B045: Deep genomic and single cell molecular profiles define immunogenic pancreatic cancer

Free
Wungki Park, Shigeaki Umeda, Catherine O'Connor, Haochen Zhang, Roshan Sharma, Allison Richards, Yingjie Zhu, Elias-Ramzey Karnoub, Xin Pei, Anna M. Varghese, Kevin Soares, Alejandro Jimenez Sanchez, Hulya Ozkan Sahin, Kenneth Yu, Vinod P. Balachandran, Joanne Chou, Fergus Keane, David Kelsen, Olca Basturk, Chaitanya Bandlamudi, Marinela Capanu, Tal Nawy, Michael Berger, Ronan Chaligne, Ghassan Abou-Alfa, Jorge S. Reis-Filho, Nadeem Riaz, Dana Pe'er, Christine A. Iacobuzio-Donahue, Eileen M. O'Reilly
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B045.
https://doi.org/10.1158/1538-7445.PANCA2023-B045
Published: 16 January 2024
View articletitled, Abstract B045: Deep genomic and single cell molecular profiles define immunogenic pancreatic cancer
Journal Articles

Abstract PR007: ERG-driven luminal prostate cancers emerge from Ck5+/Nkx3.1+ basal cells

Free
Weiran Feng, Erik Ladewig, Nazifa Salsabeel, Huiyong Zhao, Young Sun Lee, Anuradha Gopalan, Hanzhi Luo, Wenfei Kang, Ning Fan, Eric Rosiek, Ignas Masilionis, Katia Manova-Todorova, Ronan Chaligné, Elisa de Stanchina, Brett S. Carver, Yu Chen, Dong Gao, Christina S. Leslie, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): PR007.
https://doi.org/10.1158/1538-7445.PRCA2023-PR007
Published: 02 June 2023
View articletitled, Abstract PR007: ERG-driven luminal prostate cancers emerge from Ck5+/Nkx3.1+ basal cells
Journal Articles

Abstract 1167: Single-cell transcriptomic profiling of SCLC transformation reveals increased intratumoral diversity of variant and non-neuroendocrine subtypes

Free
Joseph Minhow Chan, Alvaro Quintanal-Villalonga, Amin Sabet, Parvathy Manoj, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Jacklynn Egger, Noor Sohail, Jaeyoung Chun, Tal Nawy, Linas Mazutis, Triparna Sen, Ronan Chaligne, Helena Yu, Dana Pe'er, Charles Rudin
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1167.
https://doi.org/10.1158/1538-7445.AM2023-1167
Published: 04 April 2023
View articletitled, Abstract 1167: Single-cell transcriptomic profiling of SCLC transformation reveals increased intratumoral diversity of variant and non-neuroendocrine subtypes
Journal Articles

Abstract 1241: A single cell landscape of malignant pancreas cancer ascites

Free
Shigeaki Umeda, Elias- Ramzey Karnoub, Etay Ziv, Jean Wu, Cristian Cruz, Wungki Park, Fiyinfolu Balogun, Alejandro Jiménez- Sánchez, Ronan Chaligné, Eileen M. O'Reilly, Christine A. Iacobuzio- Donahue
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1241.
https://doi.org/10.1158/1538-7445.AM2023-1241
Published: 04 April 2023
View articletitled, Abstract 1241: A single cell landscape of malignant pancreas cancer ascites
Journal Articles

Abstract 1517: Genetic characterization of normal pancreas tissue using single-cell technology

Free
Elias-Ramzey R. Karnoub, Haochen Zhang, Shigeaki Umeda, Ignas Masilionis, Ronan Chaligné, Christine Iacobuzio-Donahue
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1517.
https://doi.org/10.1158/1538-7445.AM2023-1517
Published: 04 April 2023
View articletitled, Abstract 1517: Genetic characterization of normal pancreas tissue using single-cell technology
Journal Articles

Abstract 6421: Molecular profiles and single cell analysis identify immunogenic pancreatic ductal adenocarcinoma (iPDAC)

Free
Wungki Park, Catherine O'Connor, Shigeaki Umeda, Roshan Sharma, Yingjie Zhu, Elias-Ramzey Karnoub, Anna Varghese, Kevin C. Soares, Alejandro Jimemez, Asli Yavas, Kenneth H. Yu, Balachandran P. Vinod, Joanne F. Chou, Danny N. Khalil, Kelsen David, Hulya Sahin Ozkan, Olca Basturk, Marinela Capanu, Tal Nawy, Michael F. Berger, Ghassan K. Abou-Alfa, Jorge S. Reis-Filho, Ronan Chaligne, Nadeem Riaz, Dana Pe'er, Christine Iacobuzio-Donahue, Eileen M. O'Reilly
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6421.
https://doi.org/10.1158/1538-7445.AM2023-6421
Published: 04 April 2023
View articletitled, Abstract 6421: Molecular profiles and single cell analysis identify immunogenic pancreatic ductal adenocarcinoma (iPDAC)
Journal Articles

Abstract C012: Dissecting the reorganization of pancreatic tumor microenvironments after radiation and immunotherapy reveals insights into immunotherapy resistance

Free
Arnav Mehta, Aparna Parikh, Milan Parikh, Ryan Park, Moshe Sade-Feldman, Lynn Bi, Nicole Carzo, Tarin M. Grillo, Islam Baiev, Olanike Asupoto, Irena Gushterova, Tom LaSalle, Anna Gonye, Emily Blaum, Sebastien Vigneau, Ronan Chaligne, Ana Lako, Thomas Lila, David Nelson, Caroline Porter, Orr Ashenberg, Karthik Jagadesh, William L. Hwang, Christopher Smillie, David P. Ryan, David T. Ting, Theodore Hong, Dana Pe'er, Nir Hacohen
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C012.
https://doi.org/10.1158/1538-7445.PANCA22-C012
Published: 15 November 2022
View articletitled, Abstract C012: Dissecting the reorganization of pancreatic tumor microenvironments after radiation and immunotherapy reveals insights into immunotherapy resistance
Journal Articles

Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State

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Kenneth L. Pitter, Olivera Grbovic-Huezo, Simon Joost, Anupriya Singhal, Melissa Blum, Katherine Wu, Matilda Holm, Alexander Ferrena, Arjun Bhutkar, Anna Hudson, Nicolas Lecomte, Elisa de Stanchina, Ronan Chaligne, Christine A. Iacobuzio-Donahue, Dana Pe'er, Tuomas Tammela
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3549–3560.
https://doi.org/10.1158/0008-5472.CAN-22-1742
Published: 04 October 2022
View articletitled, Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State
Open the PDF for Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State in another window
Includes: Supplementary data
Journal Articles

Abstract 59: Optimization of high-throughput, high-depth, targeted single-cell DNA sequencing to pancreatic ductal adenocarcinoma

Free
Haochen Zhang, Elias-Ramzey Karnoub, Ronan Chaligné, Ignas Masilionis, Alvin Makohon-Moore, Jungeui Hong, Christine Iacobuzio-Donahue
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 59.
https://doi.org/10.1158/1538-7445.AM2022-59
Published: 15 June 2022
View articletitled, Abstract 59: Optimization of high-throughput, high-depth, targeted single-cell DNA sequencing to pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1594: Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition

Free
Joseph M. Chan, Wouter R. Karthaus, Manu Setty, Jillian R. Love, Samir Zaidi, Jimmy Zhao, Zi-ning Choo, Sitara Persad, Justin LaClair, Kayla E. Lawrence, Ojasvi Chaudhary, Ignas Masilionis, Linas Mazutis, Ronan Chaligne, Dana Pe'er, Charles Sawyers
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1594.
https://doi.org/10.1158/1538-7445.AM2022-1594
Published: 15 June 2022
View articletitled, Abstract 1594: Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition
Journal Articles

Abstract PO-019: Deciphering differentiation hierarchies, heritability and plasticity in human gliomas via single-cell multi-omics

Free
Federico Gaiti, Ronan Chaligne, Dana Silverbush, Joshua S. Schiffman, Hannah R. Weisman, Lloyd Kluegel, Simon Gritsch, Sunil D. Deochand, Alyssa R. Richman, Johanna Klughammer, Tommaso Biancalani, Christoph Muus, Caroline Sheridan, Alicia Alonso, Franco Izzo, Orit Rozenblatt-Rosen, Aviv Regev, Mario L. Suvà, Dan A. Landau
Journal: Cancer Research
Cancer Res (2020) 80 (21_Supplement): PO-019.
https://doi.org/10.1158/1538-7445.TUMHET2020-PO-019
Published: 03 November 2020
View articletitled, Abstract PO-019: Deciphering differentiation hierarchies, heritability and plasticity in human gliomas via single-cell multi-omics