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Ronald Levy
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Journal Articles

Abstract 35: In situ CAR T cell engineering using lipid nanoparticles for B cell lymphoma therapy

Nisi Zhang, Elise Robinson, Angelie Rivera-Rodriguez, James Wang, Yutong Guo, Bo Wu, Spencer K. Tumbale, Marina Raie, Mohammed Inayathullah, Debra K. Czerwinski, Ronald Levy, Katherine W. Ferrara
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 35.
https://doi.org/10.1158/1538-7445.AM2024-35
Published: 22 March 2024
View article titled, Abstract 35: <em>In situ</em> CAR T cell engineering using lipid nanoparticles for B cell lymphoma therapy
Journal Articles

Neoadjuvant Intratumoral Immunotherapy with TLR9 Activation and Anti-OX40 Antibody Eradicates Metastatic Cancer

Wan Xing Hong, Idit Sagiv-Barfi, Debra K. Czerwinski, Adrienne Sallets, Ronald Levy
Journal: Cancer Research
Cancer Res (2022) 82 (7): 1396–1408.
https://doi.org/10.1158/0008-5472.CAN-21-1382
Published: 01 April 2022
View article titled, Neoadjuvant Intratumoral Immunotherapy with TLR9 Activation and Anti-OX40 Antibody Eradicates Metastatic Cancer
Open the PDF for Neoadjuvant Intratumoral Immunotherapy with TLR9 Activation and Anti-OX40 Antibody Eradicates Metastatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5568: Neoadjuvant immunotherapy for solid tumors

Wan Xing Hong, Idit Sagiv-Barfi, Debra Czerwinski, Ronald Levy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5568.
https://doi.org/10.1158/1538-7445.AM2020-5568
Published: 15 August 2020
View article titled, Abstract 5568: Neoadjuvant immunotherapy for solid tumors
Journal Articles

Abstract 4045: Single cell RNA sequencing of serial tumor and blood biopsies from lymphoma patients undergoing in situ vaccination

Tanaya Shree, Anuja Sathe, Hanlee Ji, Ronald Levy
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4045.
https://doi.org/10.1158/1538-7445.AM2019-4045
Published: 01 July 2019
View article titled, Abstract 4045: Single cell RNA sequencing of serial tumor and blood biopsies from lymphoma patients undergoing <em>in situ</em> vaccination
Journal Articles

Abstract CT133: Interim results of a Phase I/II trial of intratumoral CpG, local low-dose radiation, and oral ibrutinib in patients with low-grade B-cell lymphoma

Tanaya Shree, Michael S. Khodadoust, Debra Czerwinski, Matthew J. Frank, Wan X. Hong, Rachel Greenstein, Summer Guo, Steven Long, Brock A. Martin, Ronald Levy
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT133.
https://doi.org/10.1158/1538-7445.AM2019-CT133
Published: 01 July 2019
View article titled, Abstract CT133: Interim results of a Phase I/II trial of intratumoral CpG, local low-dose radiation, and oral ibrutinib in patients with low-grade B-cell lymphoma
Journal Articles

Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity

Ole Audun Werner Haabeth, Timothy R. Blake, Colin J. McKinlay, Anders A. Tveita, Adrienne Sallets, Robert M. Waymouth, Paul A. Wender, Ronald Levy
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1624–1634.
https://doi.org/10.1158/0008-5472.CAN-18-2867
Published: 01 April 2019
View article titled, Local Delivery of <em>Ox40l</em>, <em>Cd80</em>, and <em>Cd86</em> mRNA Kindles Global Anticancer Immunity
Open the PDF for Local Delivery of <em>Ox40l</em>, <em>Cd80</em>, and <em>Cd86</em> mRNA Kindles Global Anticancer Immunity in another window
Includes: Supplementary data
Journal Articles

Abstract 3031: Positron emission tomography imaging of activated T cells by targeting OX40 reveals spatiotemporal immune dynamics and predicts response to in situ tumor vaccination

Aaron T. Mayer, Israt S. Alam, Idit Sagiv-Barfi, Kezheng Wang, Ophir Vermesh, Debra K. Czerwinski, Emily M. Johnson, Michelle L. James, Ronald Levy, Sanjiv S. Gambhir
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3031.
https://doi.org/10.1158/1538-7445.AM2018-3031
Published: 01 July 2018
View article titled, Abstract 3031: Positron emission tomography imaging of activated T cells by targeting OX40 reveals spatiotemporal immune dynamics and predicts response to in situ tumor vaccination
Journal Articles

Abstract 3693: Single cell RNA-Seq of primary lymphomas reveals the diverse transcriptional states of the cancer immunologic milieu

Noemi Andor, Erin Simonds, Jiamin Chen, Christina Wood, Susan Grimes, Debra Czerwinski, Grace Zheng, Ronald Levy, Hanlee P. Ji
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3693.
https://doi.org/10.1158/1538-7445.AM2017-3693
Published: 01 July 2017
View article titled, Abstract 3693: Single cell RNA-Seq of primary lymphomas reveals the diverse transcriptional states of the cancer immunologic milieu
Journal Articles

Abstract CT047: SD-101, a novel intratumoral class C CpG-ODN, given with low-dose radiation in patients with untreated low-grade B-cell lymphoma: interim results of a phase I trial

Ronald Levy, Nancy Bartlett, Jonathan Friedberg, Patrick Reagan, Leo Gordon, Craig Bergman, Robert Coffman, Robert Janssen, Albert Candia, Michael Khodadoust, Matthew Frank, Steven Long, Debra Czerwinski, Michael Chu, Holbrook Kohrt
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT047.
https://doi.org/10.1158/1538-7445.AM2016-CT047
Published: 15 July 2016
View article titled, Abstract CT047: SD-101, a novel intratumoral class C CpG-ODN, given with low-dose radiation in patients with untreated low-grade B-cell lymphoma: interim results of a phase I trial
Journal Articles

Abstract 551: In situ vaccination with TLR9 agonist and anti-Ox40 antibody is sufficient to induce abscopal responses even in mice with spontaneous oncogene-driven tumors

Idit Sagiv-Barfi, Debra K. Czerwinski, Ronald Levy
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 551.
https://doi.org/10.1158/1538-7445.AM2016-551
Published: 15 July 2016
View article titled, Abstract 551: In situ vaccination with TLR9 agonist and anti-Ox40 antibody is sufficient to induce abscopal responses even in mice with spontaneous oncogene-driven tumors
Journal Articles

Abstract 2209: Costimulation of T cells by CD81 enhances CAR transduction of naive T cells

Liora M. Schultz, Debra Czerwinski, Chiung-Chi Kuo, Shoshana Levy, Ronald Levy
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2209.
https://doi.org/10.1158/1538-7445.AM2016-2209
Published: 15 July 2016
View article titled, Abstract 2209: Costimulation of T cells by CD81 enhances CAR transduction of naive T cells
Journal Articles

Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells

Felipe Vences-Catalán, Ranjani Rajapaksa, Minu K. Srivastava, Aurelien Marabelle, Chiung-Chi Kuo, Ronald Levy, Shoshana Levy
Journal: Cancer Research
Cancer Res (2015) 75 (21): 4517–4526.
https://doi.org/10.1158/0008-5472.CAN-15-1021
Published: 01 November 2015
View article titled, Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells
Open the PDF for Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 251: Combining Ibrutinib with immune checkpoint blockade to induce therapeutic antitumor immune response in solid tumors

Idit Sagiv-Barfi, Holbrook Kohrt, Debra Czerwinski, Patrick Ng, Betty Chang, Ronald Levy
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 251.
https://doi.org/10.1158/1538-7445.AM2015-251
Published: 01 August 2015
View article titled, Abstract 251: Combining Ibrutinib with immune checkpoint blockade to induce therapeutic antitumor immune response in solid tumors
Journal Articles

Abstract 2941: Local tumor irradiation combined with α-PDL-1 immune checkpoint inhibition results in local and systemic anti-tumor responses: Successful translation of a mouse model to a human case series

Idit Sagiv-Barfi, Amanda Rajapaksa, Debra Czerwinski, Serena Chang, Jonathan Hebb, Cariad Chester, Erin Waller, Gregg Fine, Daniel Chen, Marcin Kowanetz, Bryan Irving, Ronald Levy, Holbrook Kohrt
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2941.
https://doi.org/10.1158/1538-7445.AM2014-2941
Published: 01 October 2014
View article titled, Abstract 2941: Local tumor irradiation combined with α-PDL-1 immune checkpoint inhibition results in local and systemic anti-tumor responses: Successful translation of a mouse model to a human case series
Journal Articles

Abstract 648: Semi-synthetic peptibodies are a novel personalized therapeutic with activity against lymphoma in vitro and in vivo

James Torchia, Patrick Ng, Homer Chen, Kipp Weiskopf, Ronald Levy
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 648.
https://doi.org/10.1158/1538-7445.AM2014-648
Published: 01 October 2014
View article titled, Abstract 648: Semi-synthetic peptibodies are a novel personalized therapeutic with activity against lymphoma <em>in vitro</em> and <em>in vivo</em>
Journal Articles

Abstract IA25: Local immunomodulation at a single site of tumor generates a therapeutic immune response that cures metastatic disease at distant sites, including the brain.

Aurelien Marabelle, Holbrook Kohrt, Ronald Levy
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): IA25.
https://doi.org/10.1158/1538-7445.TUMIMM2012-IA25
Published: 02 April 2014
View article titled, Abstract IA25: Local immunomodulation at a single site of tumor generates a therapeutic immune response that cures metastatic disease at distant sites, including the brain.
Journal Articles

Abstract LB-139: In situ Treg immunomodulation at a single tumor site with CpG and immune checkpoint antibodies cures metastatic disease

aurelien marabelle, Holbrook Kohrt, Joshua Brody, James Torchia, ranjani rajapaksa, Richard Luong, Gang Zhou, Hyam Levitsky, Victor Tse, Ronald Levy
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-139.
https://doi.org/10.1158/1538-7445.AM2012-LB-139
Published: 15 April 2012
View article titled, Abstract LB-139: In situ Treg immunomodulation at a single tumor site with CpG and immune checkpoint antibodies cures metastatic disease
Journal Articles

Abstract LB-138: Stimulation of natural killer cells with an anti-CD137 antibody enhances the efficacy trastuzumab, cetuximab, and rituximab in HER2-expressing breast cancer, EGFR+ head and neck cancer, and CD20+ lymphoma

Holbrook Kohrt, Roch Houot, Kipp Weiskopf, Matthew Goldstein, Peder Lund, Debra Czerwinski, John Sunwoo, Thomas Tedder, Lieping Chen, Ronald Levy
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-138.
https://doi.org/10.1158/1538-7445.AM2012-LB-138
Published: 15 April 2012
View article titled, Abstract LB-138: Stimulation of natural killer cells with an anti-CD137 antibody enhances the efficacy trastuzumab, cetuximab, and rituximab in HER2-expressing breast cancer, EGFR+ head and neck cancer, and CD20+ lymphoma
Journal Articles

Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells

Matthew J. Goldstein, Holbrook E. Kohrt, Roch Houot, Bindu Varghese, Jack T. Lin, Erica Swanson, Ronald Levy
Journal: Cancer Research
Cancer Res (2012) 72 (5): 1239–1247.
https://doi.org/10.1158/0008-5472.CAN-11-3375
Published: 01 March 2012
View article titled, Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells
Open the PDF for Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2440: CD47 is a prognostic factor and an antibody target that synergizes with rituximab to eradicate non-Hodgkin lymphoma

Mark P. Chao, Ash A. Alizadeh, Chad Z. Tang, June H. Myklebust, Bindu Varghese, Max Jan, Adriel C. Cha, Brent T. Tan, Christopher Y. Park, Ronald Levy, Irving L. Weissman, Ravindra Majeti
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2440.
https://doi.org/10.1158/1538-7445.AM10-2440
Published: 15 April 2010
View article titled, Abstract 2440: CD47 is a prognostic factor and an antibody target that synergizes with rituximab to eradicate non-Hodgkin lymphoma