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Rolf Bjerkvig
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Journal Articles

Abstract LB-295: Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma

Mingzhi Han, Shuai Wang, Xingang Li, Jian Wang, Rolf Bjerkvig
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-295.
https://doi.org/10.1158/1538-7445.AM2019-LB-295
Published: 01 July 2019
View article titled, Abstract LB-295: Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma
Journal Articles

Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma

Giorgia Mastrella, Mengzhuo Hou, Min Li, Veit M. Stoecklein, Nina Zdouc, Marie N.M. Volmar, Hrvoje Miletic, Sören Reinhard, Christel C. Herold-Mende, Susanne Kleber, Katharina Eisenhut, Gaetano Gargiulo, Michael Synowitz, Angelo L. Vescovi, Patrick N. Harter, Josef M. Penninger, Ernst Wagner, Michel Mittelbronn, Rolf Bjerkvig, Dolores Hambardzumyan, Ulrich Schüller, Jörg-Christian Tonn, Josefine Radke, Rainer Glass, Roland E. Kälin
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2298–2313.
https://doi.org/10.1158/0008-5472.CAN-18-0881
Published: 01 May 2019
View article titled, Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma
Open the PDF for Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract LB-314: The good drug, the bad barrier and the handy peptide: Improved treatment of experimental melanoma brain metastases using a synthetic peptide

Synnøve Nymark Aasen, Heidi Espedal, Christopher Florian Holte, Olivier Keunen, Tine Veronica Karlsen, Olav Tenstad, Habib Baghirov, Dag Erlend Olberg, Rolf Bjerkvig, Gobinda Sarkar, Frits Thorsen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-314.
https://doi.org/10.1158/1538-7445.AM2018-LB-314
Published: 01 July 2018
View article titled, Abstract LB-314: The good drug, the bad barrier and the handy peptide: Improved treatment of experimental melanoma brain metastases using a synthetic peptide
Journal Articles

Abstract 2865: The peptide transporter K16ApoE increases drug delivery across the blood brain barrier in an experimental animal model of melanoma brain metastases

Synnøve Nymark Aasen, Heidi Espedal, Olivier Keunen, Christopher Florian Holte, Habib Baghirov, Rolf Bjerkvig, Tine Veronica Karlsen, Olav Tenstad, Dag Erlend Olberg, Gobinda Sarkar, Robert B Jenkins, Frits Thorsen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2865.
https://doi.org/10.1158/1538-7445.AM2017-2865
Published: 01 July 2017
View article titled, Abstract 2865: The peptide transporter K16ApoE increases drug delivery across the blood brain barrier in an experimental animal model of melanoma brain metastases
Journal Articles

Abstract 1343: P32-targeting TT1 peptide delivers nanoparticles to intracranial glioblastomas

Pille Säälik, Hedi Hunt, Allan Tobi, Anne-Mari Anton Willmore, Kadri Toome, Shweta Sharma, Ramana Kotamraju, Gabriele Bergers, Rolf Bjerkvig, Erkki Ruoslahti, Tambet Teesalu, Tambet Teesalu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1343.
https://doi.org/10.1158/1538-7445.AM2016-1343
Published: 15 July 2016
View article titled, Abstract 1343: P32-targeting TT1 peptide delivers nanoparticles to intracranial glioblastomas
Journal Articles

Abstract 4413: Thrombospondin-1 is a master regulator of glioblastoma vascularization and infiltration

Thomas Daubon, Celine Leon, Kim Clarke, Mathilde Poulet, Hrvoje Miletic, Francesco Falciani, Rolf Bjerkvig, Andreas Bikfalvi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4413.
https://doi.org/10.1158/1538-7445.AM2016-4413
Published: 15 July 2016
View article titled, Abstract 4413: Thrombospondin-1 is a master regulator of glioblastoma vascularization and infiltration
Journal Articles

Abstract 1331: Targeting CD47 triggers macrophage-dependent brain tumor destruction in a clinical relevant model

Huaiyang Zhu, Ning Yang, Lina Leiss, Cecilie B Rygh, Siddhartha S Mitra, Samuel H Cheshier, Bin Huang, Rolf Bjerkvig, Per Ø Enger, Irving L Weissman, Xingang Li, Jian Wang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1331.
https://doi.org/10.1158/1538-7445.AM2015-1331
Published: 01 August 2015
View article titled, Abstract 1331: Targeting CD47 triggers macrophage-dependent brain tumor destruction in a clinical relevant model
Journal Articles

Abstract 4036: Drug repurposing to treat melanoma brain metastases

Terje Sundstrøm, Jobin K. Varughese, Francisco Azuaje, Kjell Petersen, Clifford G. Tepper, Elizabeth Ingham, Lisa Even, Sarah Tam, Kai Ove Skaftnesmo, Morten Lund-Johansen, Rolf Bjerkvig, Katherine W. Ferrara, Frits A. Thorsen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4036.
https://doi.org/10.1158/1538-7445.AM2014-4036
Published: 01 October 2014
View article titled, Abstract 4036: Drug repurposing to treat melanoma brain metastases
Journal Articles

Abstract B84: Activated c-Src enhances hypoxia in human glioblastoma multiforme and promotes tumor angiogenesis

Eskil Eskilsson, Krishna M. Talasila, Gro V. Røsland, Lina Leiss, Narve Brekkå, Per Øystein Sakariassen, Per Øyvind Enger, Rolf Bjerkvig, Hrvoje Miletic
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): B84.
https://doi.org/10.1158/1538-7445.TIM2013-B84
Published: 01 May 2014
View article titled, Abstract B84: Activated c-Src enhances hypoxia in human glioblastoma multiforme and promotes tumor angiogenesis
Journal Articles

Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model

Terje Sundstrøm, Inderjit Daphu, Ingvild Wendelbo, Erlend Hodneland, Arvid Lundervold, Heike Immervoll, Kai Ove Skaftnesmo, Michal Babic, Pavla Jendelova, Eva Sykova, Morten Lund-Johansen, Rolf Bjerkvig, Frits Thorsen
Journal: Cancer Research
Cancer Res (2013) 73 (8): 2445–2456.
https://doi.org/10.1158/0008-5472.CAN-12-3514
Published: 15 April 2013
View article titled, Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2650: Age-dependent association between protein expression of the embryonic stem cell marker Cripto-1 and survival of glioblastoma patients.

Berit B. Tysnes, Hege AA Sætran, Sverre J. Mørk, Naira V. Margaryan, Geir E. Eide, Rolf Bjerkvig, Luigi Strizzi, Mary J.C. Hendrix
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2650.
https://doi.org/10.1158/1538-7445.AM2013-2650
Published: 15 April 2013
View article titled, Abstract 2650: Age-dependent association between protein expression of the embryonic stem cell marker Cripto-1 and survival of glioblastoma patients.
Journal Articles

Abstract 2699: Organ-specific signatures of melanoma metastasis.

Terje Sundstrøm, Lars Prestegarden, Clifford Tepper, Elizabeth Ingham, Lisa Even, Sarah Johnson, Kai Ove Skaftnesmo, Morten Lund-Johansen, Rolf Bjerkvig, Katherine Ferrara, Frits Thorsen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2699.
https://doi.org/10.1158/1538-7445.AM2013-2699
Published: 15 April 2013
View article titled, Abstract 2699: Organ-specific signatures of melanoma metastasis.
Journal Articles

Abstract LB-518: Amplification and activation of EGFR wild-type mediates invasion of human glioblastoma in vivo

Krishna M. Talasila, Anke Soentgerath, Philipp Euskirchen, Gro V. Rosland, Jian Wang, Peter C. Huszthy, Lars Prestegarden, Kai Ove Skaftnesmo, Per Øystein Sakariassen, Eskil Eskilsson, Olivier Keunen, Narve Brekka, Ingrid Moen, Janice Nigro, Olav Vintermyr, Morten Lund-Johansen, Sverrre J. Mørk, Per Øyvind Enger, Rolf Bjerkvig, Hrvoje Miletic
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-518.
https://doi.org/10.1158/1538-7445.AM2012-LB-518
Published: 15 April 2012
View article titled, Abstract LB-518: Amplification and activation of EGFR wild-type mediates invasion of human glioblastoma in vivo
Journal Articles

Abstract 5279: Over-expression of EGFRviii induces an angiogenic switch in infiltrative human glioblastomas

Gro V. Røsland, Krishna Talasila, Rolf Bjerkvig, Hrvoje Miletic
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5279.
https://doi.org/10.1158/1538-7445.AM2012-5279
Published: 15 April 2012
View article titled, Abstract 5279: Over-expression of EGFRviii induces an angiogenic switch in infiltrative human glioblastomas
Journal Articles

Abstract 1725: Activation of the p53 pathway by the MDM2 antagonist nutlin-3 downregulates the DNA repair protein hABH2 and sensitizes glioma cells to chemotherapy

Tor-Christian A. Johannessen, Lars Prestegarden, Amra Grudic, Berit B. Tysnes, Rolf Bjerkvig
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1725.
https://doi.org/10.1158/1538-7445.AM2011-1725
Published: 15 April 2011
View article titled, Abstract 1725: Activation of the p53 pathway by the MDM2 antagonist nutlin-3 downregulates the DNA repair protein hABH2 and sensitizes glioma cells to chemotherapy
Journal Articles

Abstract 5229: Single, pre-labeled metastatic melanoma cells can be detected in the mouse brain using MRI

Inderjit K. Daphu, Ingvild Wendelbo, Heike Immervoll, Eva Sykova, Pavla Jendelova, Michel Babic, Rolf Bjerkvig, Frits Thorsen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5229.
https://doi.org/10.1158/1538-7445.AM2011-5229
Published: 15 April 2011
View article titled, Abstract 5229: Single, pre-labeled metastatic melanoma cells can be detected in the mouse brain using MRI
Journal Articles

Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track – Letter

Anja Torsvik, Gro V. Røsland, Agnete Svendsen, Anders Molven, Heike Immervoll, Emmet McCormack, Per Eystein Lønning, Monika Primon, Ewa Sobala, Joerg-Christian Tonn, Roland Goldbrunner, Christian Schichor, Josef Mysliwietz, Tamara T. Lah, Helena Motaln, Stian Knappskog, Rolf Bjerkvig
Journal: Cancer Research
Cancer Res (2010) 70 (15): 6393–6396.
https://doi.org/10.1158/0008-5472.CAN-10-1305
Published: 28 July 2010
View article titled, Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track – Letter
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Journal Articles

Glioma Cell Populations Grouped by Different Cell Type Markers Drive Brain Tumor Growth

Lars Prestegarden, Agnete Svendsen, Jian Wang, Linda Sleire, Kai Ove Skaftnesmo, Rolf Bjerkvig, Tao Yan, Lasse Askland, Andreas Persson, Per Øystein Sakariassen, Per Øyvind Enger
Journal: Cancer Research
Cancer Res (2010) 70 (11): 4274–4279.
https://doi.org/10.1158/0008-5472.CAN-09-3904
Published: 01 June 2010
View article titled, Glioma Cell Populations Grouped by Different Cell Type Markers Drive Brain Tumor Growth
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Includes: Supplementary data
Journal Articles

Abstract 3641: The DNA repair protein hABH2 mediates temozolomide resistance in human glioblastoma cells

Tor-Christian A. Johannessen, Lars Prestegarden, Berit B. Tysnes, Rolf Bjerkvig
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3641.
https://doi.org/10.1158/1538-7445.AM10-3641
Published: 15 April 2010
View article titled, Abstract 3641: The DNA repair protein hABH2 mediates temozolomide resistance in human glioblastoma cells
Journal Articles

Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation

Gro Vatne Røsland, Agnete Svendsen, Anja Torsvik, Ewa Sobala, Emmet McCormack, Heike Immervoll, Josef Mysliwietz, Joerg-Christian Tonn, Roland Goldbrunner, Per Eystein Lønning, Rolf Bjerkvig, Christian Schichor
Journal: Cancer Research
Cancer Res (2009) 69 (13): 5331–5339.
https://doi.org/10.1158/0008-5472.CAN-08-4630
Published: 01 July 2009
View article titled, Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation
Open the PDF for Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation in another window