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Journal Articles

Abstract LB251: Blocking genomic instability delays acquired resistance to MAPK inhibitor therapy in melanoma

Prashanthi Dharanipragada, Xiao Zhang, Sixue Liu, Shirley H. Lomeli, Aayoung Hong, Yan Wang, Zhentao Yang, Agustin Vega-Crespo, Antoni Ribas, Stergios J. Moschos, Gatien Moriceau, Roger S. Lo
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB251.
https://doi.org/10.1158/1538-7445.AM2023-LB251
Published: 14 April 2023
View articletitled, Abstract LB251: Blocking genomic instability delays acquired resistance to MAPK inhibitor therapy in melanoma
Journal Articles

Abstract B07: Rho-mediated gene transcription promotes BRAFi resistance in de-differentiated melanoma cells

Sean A. Misek, Kate M. Appleton, Tom S. Dexheimer, Erika M. Lisabeth, Roger S. Lo, Scott D. Larsen, Kathleen A. Gallo, Richard R. Neubig
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): B07.
https://doi.org/10.1158/1538-7445.MEL2019-B07
Published: 02 October 2020
View articletitled, Abstract B07: Rho-mediated gene transcription promotes BRAFi resistance in de-differentiated melanoma cells
Journal Articles

Abstract 928: Preventing melanoma from healing itself after therapy-induced immune attack through IPRES blockade

Marco Piva, Lu Sun, Gatien Moriceau, Zhentao Yang, Antoni Ribas, Willy Hugo, Roger S. Lo
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 928.
https://doi.org/10.1158/1538-7445.AM2019-928
Published: 01 July 2019
View articletitled, Abstract 928: Preventing melanoma from healing itself after therapy-induced immune attack through IPRES blockade
Journal Articles

Abstract NG04: Immune evasion mechanisms in melanoma resistant to targeted- and/or immunotherapy

Willy Hugo, Lu Sun, Marco Piva, Shirley Lomeli, Chunying Song, Antoni Ribas, Roger S. Lo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): NG04.
https://doi.org/10.1158/1538-7445.AM2018-NG04
Published: 01 July 2018
View articletitled, Abstract NG04: Immune evasion mechanisms in melanoma resistant to targeted- and/or immunotherapy
Journal Articles

Abstract 1180: Quantifying melanoma drug resistance and tumor heterogeneity by live cell interferometry

Kevin A. Leslie, Dian Huang, Graeme Murray, Daniel Guest, Irena J. Roy, Marco Piva, Gatien Moriceau, Roger S. Lo, Michael A. Teitell, Jason C. Reed
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1180.
https://doi.org/10.1158/1538-7445.AM2018-1180
Published: 01 July 2018
View articletitled, Abstract 1180: Quantifying melanoma drug resistance and tumor heterogeneity by live cell interferometry
Journal Articles

Abstract NG04: Mechanisms of resistance to anti-PD-1 immunotherapy through interferon pathway mutations

Jesse Zaretsky, Angel Garcia-Diaz, Daniel S. Shin, Helena Escuin-Ordinas, Willy Hugo, Siwen Hu-Lieskovan, Zeynep Eroglu, Davis Y. Torrejon, Paul C. Tumeh, Roger S. Lo, Antoni Ribas
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): NG04.
https://doi.org/10.1158/1538-7445.AM2017-NG04
Published: 01 July 2017
View articletitled, Abstract NG04: Mechanisms of resistance to anti-PD-1 immunotherapy through interferon pathway mutations
Journal Articles

Abstract LB-428: RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors

Poulikos I. Poulikakos, Yogindra Persaud, Manickam Janakiraman, Xiangju Kong, Charles Ng, Gatien Moriceau, Hubing Shi, Mohammad Atefi, Bjoern Titz, May Tal Gabay, Maayan Salton, Kimberly B. Dahlman, Madhavi Tadi, Jennifer A. Wargo, Keith T. Flaherty, Mark C. Kelley, Tom Misteli, Paul B. Chapman, Jeffrey A. Sosman, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Neal Rosen, David B. Solit
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-428.
https://doi.org/10.1158/1538-7445.AM2012-LB-428
Published: 15 April 2012
View articletitled, Abstract LB-428: RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors
Journal Articles

Combinatorial Treatments That Overcome PDGFRβ-Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition

Hubing Shi, Xiangju Kong, Antoni Ribas, Roger S. Lo
Journal: Cancer Research
Cancer Res (2011) 71 (15): 5067–5074.
https://doi.org/10.1158/0008-5472.CAN-11-0140
Published: 28 July 2011
View articletitled, Combinatorial Treatments That Overcome PDGFRβ-Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition
Open the PDF for Combinatorial Treatments That Overcome PDGFRβ-Driven Resistance of Melanoma Cells to V600EB-RAF Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 714: A potential epigenetic regulation of PDGFRβ overexpression in melanomas acquiring resistance to PLX4032

Ramin Nazarian, Roberto Ferrari, Xiangju Kong, Siavash K. Kurdistani, Roger S. Lo
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 714.
https://doi.org/10.1158/1538-7445.AM2011-714
Published: 15 April 2011
View articletitled, Abstract 714: A potential epigenetic regulation of PDGFRβ overexpression in melanomas acquiring resistance to PLX4032
Journal Articles

Abstract 634: Combinatorial targeting in melanoma cell lines with defined and distinct mechanisms of acquired resistance to V600EB-RAF inhibition

Hubing Shi, Xiangju Kong, Antoni Ribas, Roger S. Lo
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 634.
https://doi.org/10.1158/1538-7445.AM2011-634
Published: 15 April 2011
View articletitled, Abstract 634: Combinatorial targeting in melanoma cell lines with defined and distinct mechanisms of acquired resistance to V600EB-RAF inhibition
Journal Articles

Transforming Growth Factor-β Activation Promotes Genetic Context–Dependent Invasion of Immortalized Melanocytes

Roger S. Lo, Owen N. Witte
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4248–4257.
https://doi.org/10.1158/0008-5472.CAN-07-5671
Published: 02 June 2008
View articletitled, Transforming Growth Factor-β Activation Promotes Genetic Context–Dependent Invasion of Immortalized Melanocytes
Open the PDF for Transforming Growth Factor-β Activation Promotes Genetic Context–Dependent Invasion of Immortalized Melanocytes in another window
Includes: Supplementary data
Journal Articles

TβR-I(6A) Is a Candidate Tumor Susceptibility Allele

Boris Pasche, Prema Kolachana, Khedoudja Nafa, Jaya Satagopan, Ye-Guang Chen, Roger S. Lo, Dara Brener, Diana Yang, Laurie Kirstein, Carole Oddoux, Harry Ostrer, Paolo Vineis, Liliana Varesco, Suresh Jhanwar, Lucio Luzzatto, Joan Massagué, Kenneth Offit
Journal: Cancer Research
Cancer Res (1999) 59 (22): 5678–5682.
Published: 01 November 1999
View articletitled, TβR-I(6A) Is a Candidate Tumor Susceptibility Allele
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