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Roger R. Reddel
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Journal Articles

Abstract 5391: Machine learning of cancer type and tissue of origin from proteomes of 1,277 human tissue samples and 975 cancer cell lines

Zhaoxiang Cai, Zainab Noor, Adel T. Aref, Emma L. Boys, Dylan Xavier, Natasha Lucas, Steven G. Williams, Jennifer M. Koh, Rebecca C. Poulos, Peter G. Hains, Phillip J. Robinson, Rosemary Balleine, Roger R. Reddel, Qing Zhong
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5391.
https://doi.org/10.1158/1538-7445.AM2023-5391
Published: 04 April 2023
View article titled, Abstract 5391: Machine learning of cancer type and tissue of origin from proteomes of 1,277 human tissue samples and 975 cancer cell lines
Journal Articles

Abstract 5479: A six-protein signature predicts response and survival in patients with advanced cutaneous melanoma treated with immunotherapy

Srikanth Manda, Adel T. Aref, Erin K. Sykes, Steven G. Williams, Jennifer M. Koh, Erin M. Humphries, Daniel Bucio-Noble, Daniela Lee-Smith, Natasha Lucas, Dylan Xavier, Alexander Menzies, Ines Da Silva, Felicity Newell, Rosemary Balleine, Peter G. Hains, Graham Mann, Phil J. Robinson, Georgina V. Long, James Wilmott, Qing Zhong, Richard A. Scolyer, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5479.
https://doi.org/10.1158/1538-7445.AM2023-5479
Published: 04 April 2023
View article titled, Abstract 5479: A six-protein signature predicts response and survival in patients with advanced cutaneous melanoma treated with immunotherapy
Journal Articles

Abstract 2209: A proteomic-based prognostic signature of pancreatic adenocarcinoma

Adel T. Aref, AKM Azad, Asim Anees, Mohashin Pathan, Jason Grealey, Daniela-Lee Smith, Erin M. Humphries, Daniel Bucio-Noble, Jennifer M. Koh, Erin Sykes, Steven G. Williams, Ruth Lyons, Natasha Lucas, Dylan Xavier, Sumit Sahni, Anubhav Mittal, Jaswinder S. Samra, John V. Pearson, Nicola Waddell, Peter G. Hains, Phil J. Robinson, Qing Zhong, Roger R. Reddel, Anthony J. Gill
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2209.
https://doi.org/10.1158/1538-7445.AM2023-2209
Published: 04 April 2023
View article titled, Abstract 2209: A proteomic-based prognostic signature of pancreatic adenocarcinoma
Journal Articles

Abstract 3768: Identification of new alternative lengthening of telomeres (ALT)-positive cancer cell lines using the C-circle assay

Andrei G. Malykh, Jonathan R. Doyle, Fang Tian, Joyce HY Lee, Jeremy D. Henson, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3768.
https://doi.org/10.1158/1538-7445.AM2015-3768
Published: 01 August 2015
View article titled, Abstract 3768: Identification of new alternative lengthening of telomeres (ALT)-positive cancer cell lines using the C-circle assay
Journal Articles

STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer

Cristina Peña, María Virtudes Céspedes, Maja Bradic Lindh, Sara Kiflemariam, Artur Mezheyeuski, Per-Henrik Edqvist, Christina Hägglöf, Helgi Birgisson, Linda Bojmar, Karin Jirström, Per Sandström, Eleonor Olsson, Srinivas Veerla, Alberto Gallardo, Tobias Sjöblom, Andy C.-M. Chang, Roger R. Reddel, Ramón Mangues, Martin Augsten, Arne Östman
Journal: Cancer Research
Cancer Res (2013) 73 (4): 1287–1297.
https://doi.org/10.1158/0008-5472.CAN-12-1875
Published: 14 February 2013
View article titled, STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract 4597: Telomere maintenance mechanism and expression in colorectal cancer

Sandra Sampl, Juliane Hadolt, Philip Kienzl, Tamara Braunschmid, Stefan Stättner, Jeremy D. Henson, Roger R. Reddel, Brigitte Marian, Klaus Holzmann
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4597.
https://doi.org/10.1158/1538-7445.AM2012-4597
Published: 15 April 2012
View article titled, Abstract 4597: Telomere maintenance mechanism and expression in colorectal cancer
Journal Articles

PAX8 Regulates Telomerase Reverse Transcriptase and Telomerase RNA Component in Glioma

Yu-Jen Chen, Hamish G. Campbell, Anna K. Wiles, Michael R. Eccles, Roger R. Reddel, Antony W. Braithwaite, Janice A. Royds
Journal: Cancer Research
Cancer Res (2008) 68 (14): 5724–5732.
https://doi.org/10.1158/0008-5472.CAN-08-0058
Published: 15 July 2008
View article titled, PAX8 Regulates Telomerase Reverse Transcriptase and Telomerase RNA Component in Glioma
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Includes: Supplementary data
Journal Articles

Amplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression Levels

Ying Cao, Lily I. Huschtscha, Amanda S. Nouwens, Hilda A. Pickett, Axel A. Neumann, Andy C-M. Chang, Christian D. Toouli, Tracy M. Bryan, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2008) 68 (9): 3115–3123.
https://doi.org/10.1158/0008-5472.CAN-07-6377
Published: 01 May 2008
View article titled, Amplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression Levels
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Includes: Supplementary data
Journal Articles

Concordant Epigenetic Silencing of Transforming Growth Factor-β Signaling Pathway Genes Occurs Early in Breast Carcinogenesis

Rebecca A. Hinshelwood, Lily I. Huschtscha, John Melki, Clare Stirzaker, Andrea Abdipranoto, Bryce Vissel, Timothy Ravasi, Christine A. Wells, David A. Hume, Roger R. Reddel, Susan J. Clark
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11517–11527.
https://doi.org/10.1158/0008-5472.CAN-07-1284
Published: 18 December 2007
View article titled, Concordant Epigenetic Silencing of Transforming Growth Factor-β Signaling Pathway Genes Occurs Early in Breast Carcinogenesis
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Includes: Supplementary data
Journal Articles

DNA Damage Induces Alternative Lengthening of Telomeres (ALT)–Associated Promyelocytic Leukemia Bodies that Preferentially Associate with Linear Telomeric DNA

Clare L. Fasching, Axel A. Neumann, Alessandra Muntoni, Thomas R. Yeager, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2007) 67 (15): 7072–7077.
https://doi.org/10.1158/0008-5472.CAN-07-1556
Published: 01 August 2007
View article titled, DNA Damage Induces Alternative Lengthening of Telomeres (ALT)–Associated Promyelocytic Leukemia Bodies that Preferentially Associate with Linear Telomeric DNA
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Journal Articles

Telomere Maintenance Mechanisms in Liposarcomas: Association with Histologic Subtypes and Disease Progression

Aurora Costa, Maria Grazia Daidone, Laura Daprai, Raffaella Villa, Sabrina Cantù, Silvana Pilotti, Luigi Mariani, Alessandro Gronchi, Jeremy D. Henson, Roger R. Reddel, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8918–8924.
https://doi.org/10.1158/0008-5472.CAN-06-0273
Published: 01 September 2006
View article titled, Telomere Maintenance Mechanisms in Liposarcomas: Association with Histologic Subtypes and Disease Progression
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Journal Articles

Association of Mutant TP53 with Alternative Lengthening of Telomeres and Favorable Prognosis in Glioma

Yu-Jen Chen, Vicky Hakin-Smith, Mario Teo, George E. Xinarianos, David A. Jellinek, Thomas Carroll, David McDowell, Martin R. MacFarlane, Ronald Boet, Bruce C. Baguley, Antony W. Braithwaite, Roger R. Reddel, Janice A. Royds
Journal: Cancer Research
Cancer Res (2006) 66 (13): 6473–6476.
https://doi.org/10.1158/0008-5472.CAN-06-0910
Published: 03 July 2006
View article titled, Association of Mutant <em>TP53</em> with Alternative Lengthening of Telomeres and Favorable Prognosis in Glioma
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Journal Articles

Expression and clinical relevance of alternative lengthening of telomeres (ALT) in human liposarcomas

Aurora Costa, Maria Grazia Daidone, Laura Daprai, Raffaella Villa, Silvana Pilotti, Alessandro Gronchi, Jeremy D. Henson, Roger R. Reddel, Nadia Zaffaroni
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1021.
Published: 01 May 2005
View article titled, Expression and clinical relevance of alternative lengthening of telomeres (ALT) in human liposarcomas
Journal Articles

Telomerase-Independent Telomere Length Maintenance in the Absence of Alternative Lengthening of Telomeres–Associated Promyelocytic Leukemia Bodies

Clare L. Fasching, Kylie Bower, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2005) 65 (7): 2722–2729.
https://doi.org/10.1158/0008-5472.CAN-04-2881
Published: 01 April 2005
View article titled, Telomerase-Independent Telomere Length Maintenance in the Absence of Alternative Lengthening of Telomeres–Associated Promyelocytic Leukemia Bodies
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Journal Articles

Alternative Lengthening of Telomeres Is Characterized by High Rates of Telomeric Exchange

J. Arturo Londoño-Vallejo, Héra Der-Sarkissian, Lucien Cazes, Silvia Bacchetti, Roger R. Reddel
Journal: Cancer Research
Cancer Res (2004) 64 (7): 2324–2327.
https://doi.org/10.1158/0008-5472.CAN-03-4035
Published: 01 April 2004
View article titled, Alternative Lengthening of Telomeres Is Characterized by High Rates of Telomeric Exchange
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Journal Articles

Rhodacyanine Dye MKT-077 Inhibits in Vitro Telomerase Assay But Has No Detectable Effects on Telomerase Activity in Vivo

Renu Wadhwa, Lorel Colgin, Tomoko Yaguchi, Kazunari Taira, Roger R. Reddel, Sunil C. Kaul
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4434–4438.
Published: 01 August 2002
View article titled, Rhodacyanine Dye MKT-077 Inhibits <em>in Vitro</em> Telomerase Assay But Has No Detectable Effects on Telomerase Activity <em>in Vivo</em>
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Journal Articles

Stanniocalcin 2 Is an Estrogen-responsive Gene Coexpressed with the Estrogen Receptor in Human Breast Cancer

Toula Bouras, Melissa C. Southey, Andy C. Chang, Roger R. Reddel, Dorian Willhite, Richard Glynne, Michael A. Henderson, Jane E. Armes, Deon J. Venter
Journal: Cancer Research
Cancer Res (2002) 62 (5): 1289–1295.
Published: 01 March 2002
View article titled, <em>Stanniocalcin 2</em> Is an Estrogen-responsive Gene Coexpressed with the Estrogen Receptor in Human Breast Cancer
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Journal Articles

Selective Toxicity of MKT-077 to Cancer Cells Is Mediated by Its Binding to the hsp70 Family Protein mot-2 and Reactivation of p53 Function

Renu Wadhwa, Takashi Sugihara, Akiko Yoshida, Hitoshi Nomura, Roger R. Reddel, Richard Simpson, Hiroshi Maruta, Sunil C. Kaul
Journal: Cancer Research
Cancer Res (2000) 60 (24): 6818–6821.
Published: 01 December 2000
View article titled, Selective Toxicity of MKT-077 to Cancer Cells Is Mediated by Its Binding to the hsp70 Family Protein mot-2 and Reactivation of p53 Function
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Journal Articles

Methylation of the Human Telomerase Gene CpG Island

Scott K. Dessain, Hua-yin Yu, Roger R. Reddel, Roderick L. Beijersbergen, Robert A. Weinberg
Journal: Cancer Research
Cancer Res (2000) 60 (3): 537–541.
Published: 01 February 2000
View article titled, Methylation of the Human Telomerase Gene CpG Island
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Journal Articles

Telomerase-negative Immortalized Human Cells Contain a Novel Type of Promyelocytic Leukemia (PML) Body

Thomas R. Yeager, Axel A. Neumann, Anna Englezou, Lily I. Huschtscha, Jane R. Noble, Roger R. Reddel
Journal: Cancer Research
Cancer Res (1999) 59 (17): 4175–4179.
Published: 01 September 1999
View article titled, Telomerase-negative Immortalized Human Cells Contain a Novel Type of Promyelocytic Leukemia (PML) Body
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