1-20 of 41
Roderick T. Bronson
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma

Shawn M. Davidson, Daniel R. Schmidt, Julia E. Heyman, James P. O'Brien, Amy C. Liu, William J. Israelsen, Talya L. Dayton, Raghav Sehgal, Roderick T. Bronson, Elizaveta Freinkman, Howard H. Mak, Giuseppe Nicolò Fanelli, Scott Malstrom, Gary Bellinger, Arkaitz Carracedo, Pier Paolo Pandolfi, Kevin D. Courtney, Abhishek Jha, Ronald A. DePinho, James W. Horner, Craig J. Thomas, Lewis C. Cantley, Massimo Loda, Matthew G. Vander Heiden
Journal: Cancer Research
Cancer Res (2022) 82 (13): 2403–2416.
https://doi.org/10.1158/0008-5472.CAN-21-2352
Published: 05 July 2022
View articletitled, Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
Open the PDF for Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Manav Gupta, Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson, Francisco J. Sanchez-Rivera, Patrizia Pessina, Jonathan Y. Kim, Antoine Simoneau, Margherita Paschini, Mary C. Beytagh, Caroline R. Stanclift, Monica Schenone, D.R. Mani, Chendi Li, Audris Oh, Fei Li, Hai Hu, Angeliki Karatza, Roderick T. Bronson, Alice T. Shaw, Aaron N. Hata, Kwok-Kin Wong, Lee Zou, Steven A. Carr, Tyler Jacks, Carla F. Kim
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3841–3854.
https://doi.org/10.1158/0008-5472.CAN-20-1744
Published: 15 September 2020
View articletitled, BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
Open the PDF for BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency in another window
Includes: Supplementary data
Journal Articles

Abstract P3-11-06: Pre-clinical assessment of combined ABT-263/Navitoclax and ABT-414 or ABBV-321 treatment for EGFR-expressing TNBC

Jason J Zoeller, Aleksandr Vagodny, Veerle W. Daniels, Krishan Taneja, Benjamin Y. Tan, Yoko S. DeRose, Maihi Fujita, Alana L. Welm, Anthony Letai, Joel D. Leverson, Vincent Blot, Roderick T. Bronson, Deborah A. Dillon, Joan S. Brugge
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-11-06.
https://doi.org/10.1158/1538-7445.SABCS19-P3-11-06
Published: 15 February 2020
View articletitled, Abstract P3-11-06: Pre-clinical assessment of combined ABT-263/Navitoclax and ABT-414 or ABBV-321 treatment for EGFR-expressing TNBC
Journal Articles

Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities

Rodrigo Romero, Volkan I. Sayin, Davidson M. Shawn, Matthew Bauer, Simranjit X. Singh, Sarah LeBoeuf, Triantafyllia R. Karakousi, Donald C. Ellis, Arjun Bhutkar, Francisco Sanchez-Rivera, Lakshmipriya Subbaraj, Britney Martinez, Roderick T. Bronson, Justin R. Prigge, Edward E. Schmidt, Craig J. Thomas, Angela Davies, Igor Dolgalev, Adriana Heguy, Viola Allaj, John T. Piorier, Andre L. Moreira, Charles M. Rudin, Harvey I. Pass, Matthew G. Vander Heiden, Tyler Jacks, Thales Papagiannakopoulos
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A43.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A43
Published: 14 May 2018
View articletitled, Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities
Journal Articles

Abstract A31: Biological effects of lutein and kale on the prevention of colonic inflammation and carcinogenesis

Chun Liu, Roderick T. Bronson, Xiang-Dong Wang
Journal: Cancer Research
Cancer Res (2017) 77 (3_Supplement): A31.
https://doi.org/10.1158/1538-7445.CRC16-A31
Published: 31 January 2017
View articletitled, Abstract A31: Biological effects of lutein and kale on the prevention of colonic inflammation and carcinogenesis
Journal Articles

Abstract 4358: Neutralization of BCL2/XL enhances the cytotoxicity of T-DM1 in vivo

Jason J. Zoeller, Roderick T. Bronson, Deepak Sampath, Joel Leverson, Joan S. Brugge
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4358.
https://doi.org/10.1158/1538-7445.AM2016-4358
Published: 15 July 2016
View articletitled, Abstract 4358: Neutralization of BCL2/XL enhances the cytotoxicity of T-DM1 in vivo
Journal Articles

Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression

Douglas E. Linn, Kathryn L. Penney, Roderick T. Bronson, Lorelei A. Mucci, Zhe Li
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1869–1881.
https://doi.org/10.1158/0008-5472.CAN-15-1911
Published: 31 March 2016
View articletitled, Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression
Open the PDF for Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Tumorigenic Activity of Merkel Cell Polyomavirus T Antigens Expressed in the Stratified Epithelium of Mice

Megan E. Spurgeon, Jingwei Cheng, Roderick T. Bronson, Paul F. Lambert, James A. DeCaprio
Journal: Cancer Research
Cancer Res (2015) 75 (6): 1068–1079.
https://doi.org/10.1158/0008-5472.CAN-14-2425
Published: 12 March 2015
View articletitled, Tumorigenic Activity of Merkel Cell Polyomavirus T Antigens Expressed in the Stratified Epithelium of Mice
Open the PDF for Tumorigenic Activity of Merkel Cell Polyomavirus T Antigens Expressed in the Stratified Epithelium of Mice in another window
Includes: Supplementary data
Journal Articles

Abstract B39: Nkx2-1 down-regulation underlies lung adenocarcinoma progression towards malignancy

Monte M. Winslow, Talya L. Dayton, Eric L. Snyder, Derek Y. Chiang, Caroline Kim, Roel Verhaak, Denise Crowley, Roderick T. Bronson, Matthew Meyerson, Tyler E. Jacks
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): B39.
https://doi.org/10.1158/0008-5472.FBCR09-B39
Published: 28 October 2014
View articletitled, Abstract B39: Nkx2-1 down-regulation underlies lung adenocarcinoma progression towards malignancy
Journal Articles

Abstract 4851: Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a pan-FGFR inhibitor in a mouse model of NSCLC

Esra A. Akbay, Jeremy H. Tchaicha, Abigail Altabef, Oliver R. Mikse, Eiki Kikuchi, Kevin Rhee, Rachel Liao, Roderick T. Bronson, Lynette M. Sholl, Matthew Meyerson, Peter S. Hammerman, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4851.
https://doi.org/10.1158/1538-7445.AM2014-4851
Published: 01 October 2014
View articletitled, Abstract 4851: Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a pan-FGFR inhibitor in a mouse model of NSCLC
Journal Articles

Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis

Liling Wan, Guohong Hu, Yong Wei, Min Yuan, Roderick T. Bronson, Qifeng Yang, Javed Siddiqui, Kenneth J. Pienta, Yibin Kang
Journal: Cancer Research
Cancer Res (2014) 74 (18): 5336–5347.
https://doi.org/10.1158/0008-5472.CAN-14-1349
Published: 14 September 2014
View articletitled, Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis
Open the PDF for Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis in another window
Includes: Supplementary data
Journal Articles

Epigenetic States of Cells of Origin and Tumor Evolution Drive Tumor-Initiating Cell Phenotype and Tumor Heterogeneity

Kin-Hoe Chow, Dong-Mi Shin, Molly H. Jenkins, Emily E. Miller, David J. Shih, Seungbum Choi, Benjamin E. Low, Vivek Philip, Brad Rybinski, Roderick T. Bronson, Michael D. Taylor, Kyuson Yun
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4864–4874.
https://doi.org/10.1158/0008-5472.CAN-13-3293
Published: 01 September 2014
View articletitled, Epigenetic States of Cells of Origin and Tumor Evolution Drive Tumor-Initiating Cell Phenotype and Tumor Heterogeneity
Open the PDF for Epigenetic States of Cells of Origin and Tumor Evolution Drive Tumor-Initiating Cell Phenotype and Tumor Heterogeneity in another window
Includes: Supplementary data
Journal Articles

Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC

Jeremy H. Tchaicha, Esra A. Akbay, Abigail Altabef, Oliver R. Mikse, Eiki Kikuchi, Kevin Rhee, Rachel G. Liao, Roderick T. Bronson, Lynette M. Sholl, Matthew Meyerson, Peter S. Hammerman, Kwok-Kin Wong
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4676–4684.
https://doi.org/10.1158/0008-5472.CAN-13-3218
Published: 01 September 2014
View articletitled, Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC
Open the PDF for Kinase Domain Activation of FGFR2 Yields High-Grade Lung Adenocarcinoma Sensitive to a Pan-FGFR Inhibitor in a Mouse Model of NSCLC in another window
Includes: Supplementary data
Journal Articles

A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition

Hailing Cheng, Pixu Liu, Fan Zhang, Erbo Xu, Lynn Symonds, Carolynn E. Ohlson, Roderick T. Bronson, Sauveur-Michel Maira, Emmanuelle Di Tomaso, Jane Li, Andrea P. Myers, Lewis C. Cantley, Gordon B. Mills, Jean J. Zhao
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (1): 15–23.
https://doi.org/10.1158/0008-5472.CAN-13-0544
Published: 05 January 2014
View articletitled, A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition
Open the PDF for A Genetic Mouse Model of Invasive Endometrial Cancer Driven by Concurrent Loss of Pten and Lkb1 Is Highly Responsive to mTOR Inhibition in another window
Includes: Supplementary data
Journal Articles

Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma

Sivaraman Natarajan, Yaochen Li, Emily E. Miller, David J. Shih, Michael D. Taylor, Timothy M. Stearns, Roderick T. Bronson, Susan L. Ackerman, Jeong K. Yoon, Kyuson Yun
Journal: Cancer Research
Cancer Res (2013) 73 (17): 5381–5390.
https://doi.org/10.1158/0008-5472.CAN-13-0033
Published: 02 September 2013
View articletitled, Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma
Open the PDF for Notch1-Induced Brain Tumor Models the Sonic Hedgehog Subgroup of Human Medulloblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5393: ETV1 directs androgen metabolism and confers aggressive prostate cancer in engineered mice and patients.

Esther Baena, Zhen Shao, Douglas Linn, Kimberly Glass, Melanie Hamblen, Yuko Fujiwara, Jonghwan Kim, Minh Nguyen, Xin Zhang, Frank Godinho, Roderick T. Bronson, Lorelei Mucci, Massimo Loda, Guocheng Yuan, Zhe Li, Stuart H. Orkin
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5393.
https://doi.org/10.1158/1538-7445.AM2013-5393
Published: 15 April 2013
View articletitled, Abstract 5393: ETV1 directs androgen metabolism and confers aggressive prostate cancer in engineered mice and patients.
Journal Articles

The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation

Hyun Jung Jun, Hannah Johnson, Roderick T. Bronson, Sebastien de Feraudy, Forest White, Alain Charest
Journal: Cancer Research
Cancer Res (2012) 72 (15): 3764–3774.
https://doi.org/10.1158/0008-5472.CAN-11-3990
Published: 31 July 2012
View articletitled, The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation
Open the PDF for The Oncogenic Lung Cancer Fusion Kinase CD74-ROS Activates a Novel Invasiveness Pathway through E-Syt1 Phosphorylation in another window
Includes: Supplementary data
Journal Articles

Abstract 2965: ERG and ETV1 regulate a common transcriptional network in prostate cells but in an opposite fashion

Esther Baena, Zhen Shao, Douglas Linn, Melanie Hamblen, Kimberly Glass, Pyne Saumyadipta, Yuko Fujiwara, Frank Godinho, Jonghwan Kim, Fatima Al-Shhrour, Minh Nguyen, Guocheng Yuan, Roderick T. Bronson, Massimo Loda, Stuart H. Orkin, Zhe Li
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2965.
https://doi.org/10.1158/1538-7445.AM2012-2965
Published: 15 April 2012
View articletitled, Abstract 2965: ERG and ETV1 regulate a common transcriptional network in prostate cells but in an opposite fashion
Journal Articles

Abstract 2367: Neural progenitor cells deficient in BAX and BAK manifest progressive hyperplasia and tumorigenesis

Samuel G. Katz, Jill K. Fisher, Roderick T. Bronson, Keith L. Ligon, Loren D. Walensky
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2367.
https://doi.org/10.1158/1538-7445.AM2012-2367
Published: 15 April 2012
View articletitled, Abstract 2367: Neural progenitor cells deficient in BAX and BAK manifest progressive hyperplasia and tumorigenesis
Journal Articles

Abstract 4834: Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo

Jason J. Zoeller, Roderick T. Bronson, Tona M. Gilmer, Laura M. Selfors, Yiling Lu, Gordon B. Mills, Joan S. Brugge
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4834.
https://doi.org/10.1158/1538-7445.AM2012-4834
Published: 15 April 2012
View articletitled, Abstract 4834: Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo