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Journal Articles

Abstract 7199: The retinoid X receptor (RXR) agonist IRX4204 potentiates the efficacy of trabectedin and pioglitazone in myxoid liposarcoma preclinical models

Marina Meroni, Ilaria Craparotta, Federica Mirimao, Nicolò Panini, Paolo Ubezio, Ezia Bello, Salvatore Lorenzo Renne, Maurizio D'Incalci, Roberta Frapolli

Cancer Res (2024) 84 (6_Supplement): 7199.

https://doi.org/10.1158/1538-7445.AM2024-7199

Published: 22 March 2024

View article titled, Abstract 7199: The retinoid X receptor (RXR) agonist IRX4204 potentiates the efficacy of trabectedin and pioglitazone in myxoid liposarcoma preclinical models

Journal Articles

Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy

Maria Eugenia Riveiro, Samuel Huguet, Ramiro Vazquez, Roberta Frapolli, Guido Puricelli, Simona Sestito, Olivier Madar, Keyvan Rezai, Gianpiero Garau, Simona Rapposelli

Cancer Res (2022) 82 (12_Supplement): 2569.

https://doi.org/10.1158/1538-7445.AM2022-2569

Published: 15 June 2022

View article titled, Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy

Journal Articles

Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models

Maria Eugenia Riveiro, Roberta Frapolli, Giulia Taraboletti Giulia Taraboletti, Keyvan Rezai, Marina Meroni, Massimo Russo, Patrizia Borsotti, Chris Schultz, David Gould, Yuti Chernajovsky

Cancer Res (2021) 81 (13_Supplement): 916.

https://doi.org/10.1158/1538-7445.AM2021-916

Published: 01 July 2021

View article titled, Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models

Journal Articles

Abstract 2743: Accumulation of predicted neoantigens by MMR deficiency triggered by temozolomide treatment of human colorectal cancer

Cancer Res (2018) 78 (13_Supplement): 2743.

https://doi.org/10.1158/1538-7445.AM2018-2743

Published: 01 July 2018

View article titled, Abstract 2743: Accumulation of predicted neoantigens by MMR deficiency triggered by temozolomide treatment of human colorectal cancer

Journal Articles

Abstract 5723: Inactivation of DNA repair triggers neoantigen generation and impairs tumor growth

Cancer Res (2018) 78 (13_Supplement): 5723.

https://doi.org/10.1158/1538-7445.AM2018-5723

Published: 01 July 2018

View article titled, Abstract 5723: Inactivation of DNA repair triggers neoantigen generation and impairs tumor growth

Journal Articles

Abstract 3764: Trabectedin activity in patient-derived mesothelioma xenografts

Simonetta Andrea Licandro, Roberta Frapolli, Ezia Bello, Roberta Libener, Sara Orecchia, Federica Grosso, Maurizio D’Incalci

Cancer Res (2016) 76 (14_Supplement): 3764.

https://doi.org/10.1158/1538-7445.AM2016-3764

Published: 15 July 2016

View article titled, Abstract 3764: Trabectedin activity in patient-derived mesothelioma xenografts

Journal Articles

Abstract 1284: Lurbinectedin reduces tumor-associated macrophages and the production of inflammatory cytokines, chemokines, and angiogenic factors in preclinical models

Paola Allavena, Cristina Belgiovine, Manuela Liguori, Ezia Bello, Roberta Frapolli, Carlos M. Galmarini, Maurizio D’Incalci

Cancer Res (2016) 76 (14_Supplement): 1284.

https://doi.org/10.1158/1538-7445.AM2016-1284

Published: 15 July 2016

View article titled, Abstract 1284: Lurbinectedin reduces tumor-associated macrophages and the production of inflammatory cytokines, chemokines, and angiogenic factors in preclinical models

Journal Articles

Abstract 4821: The WEE1 inhibitor AZD-1775 has synergic activity with trabectedin or lurbinectedin in ovarian cancer cells

Sarah Uboldi, Laura Carrassa, Roberta Frapolli, Paolo Ubezio, Eugenio Erba, Maurizio D’Incalci

Cancer Res (2016) 76 (14_Supplement): 4821.

https://doi.org/10.1158/1538-7445.AM2016-4821

Published: 15 July 2016

View article titled, Abstract 4821: The WEE1 inhibitor AZD-1775 has synergic activity with trabectedin or lurbinectedin in ovarian cancer cells

Journal Articles

Abstract 1183: PPARgamma agonist promotes adipocytic differentiation and potentiates the activity of trabectedin in myxoid liposarcoma

Ezia Bello, Roberta Frapolli, Simonetta Andrea Licandro, Silvia Brich, Laura Carrassa, Roberta Sanfilippo, Alessandro Gronchi, Paolo Casali, Silvana Pilotti, Maurizio D’Incalci

Cancer Res (2016) 76 (14_Supplement): 1183.

https://doi.org/10.1158/1538-7445.AM2016-1183

Published: 15 July 2016

View article titled, Abstract 1183: PPARgamma agonist promotes adipocytic differentiation and potentiates the activity of trabectedin in myxoid liposarcoma

Journal Articles

Abstract 3526: OTX015 effects in triple-negative breast cancer (TNBC) models are independent of hypoxia conditions and synergistic with other anticancer agents

Ramiro Vázquez, Lucile Astorgues-Xerri, María E. Riveiro, Luca Beltrame, Sergio Marchini, Francesco Bertoni, Ivo Kwee, Mohamed Mohamed, Esteban Cvitkovic, Roberta Frapolli, Maurizio D'Incalci

Cancer Res (2015) 75 (15_Supplement): 3526.

https://doi.org/10.1158/1538-7445.AM2015-3526

Published: 01 August 2015

View article titled, Abstract 3526: OTX015 effects in triple-negative breast cancer (TNBC) models are independent of hypoxia conditions and synergistic with other anticancer agents

Journal Articles

Abstract 3289: PTX-008, a dual inhibitor of angiogenesis and tumor cell proliferation, potentiates the antineoplastic activity of targeted therapies in human tumor models

Katiuscia Bonezzi, Roberta Frapolli, Federica Sala, Lucile Astorgues-Xerri, Maria Serova, Eric Raymond, Esteban Cvitkovic, Kay Noel, Paolo Ubezio, Massimo Zucchetti, Maurizio D'Incalci, Raffaella Giavazzi, Giulia Taraboletti

Cancer Res (2011) 71 (8_Supplement): 3289.

https://doi.org/10.1158/1538-7445.AM2011-3289

Published: 15 April 2011

View article titled, Abstract 3289: PTX-008, a dual inhibitor of angiogenesis and tumor cell proliferation, potentiates the antineoplastic activity of targeted therapies in human tumor models

Journal Articles

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

Cancer Res (2010) 70 (6): 2235–2244.

https://doi.org/10.1158/0008-5472.CAN-09-2335

Published: 14 March 2010

View article titled, Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

Includes: Supplementary data

Journal Articles

Abstract #2679: Mechanism of action and antitumor activity of PM01183

Pablo Aviles, Carlos Galmarini, Carmen Cuevas, Maria José Guillen, Roberta Frapolli, S. Uboldi, M. Romano, M. Tavecchio, E. Erba, E. Bello, Maurizio D'Incalci

Cancer Res (2009) 69 (9_Supplement): 2679.

Published: 01 May 2009

View article titled, Abstract #2679: Mechanism of action and antitumor activity of PM01183

Journal Articles

The effect of vandetanib on tumor vasculature remodeling and paclitaxel uptake in a xenograft model of ovarian carcinoma

Marta Cesca, Roberta Frapolli, Ezia Bello, Alexander Berndt, Petra Richter, Anderson Ryan, Raffella Giavazzi

Cancer Res (2008) 68 (9_Supplement): 4762.

Published: 01 May 2008

View article titled, The effect of vandetanib on tumor vasculature remodeling and paclitaxel uptake in a xenograft model of ovarian carcinoma

Journal Articles

Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring

Giovanni L. Beretta, Giovanna Petrangolini, Michelandrea De Cesare, Graziella Pratesi, Paola Perego, Stella Tinelli, Monica Tortoreto, Massimo Zucchetti, Roberta Frapolli, Ezia Bello, Carla Manzotti, Gabriele Fontana, Ezio Bombardelli, Arturo Battaglia, Cristian Samorì, Franco Zunino

Cancer Res (2006) 66 (22): 10976–10982.

https://doi.org/10.1158/0008-5472.CAN-06-2158

Published: 15 November 2006

View article titled, Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring

Journal Articles

Antitumor activity of a new synthetic camptothecin with the open lacton ring.

Graziella Pratesi, Giovanni L. Beretta, Michelandrea De Cesare, Giovanna Petrangolini, Maria Stella Tinelli, Massimo Zucchetti, Roberta Frapolli, Carla Manzotti, Ezio Bombardelli, Franco Zunino

Cancer Res (2006) 66 (8_Supplement): 1301.

Published: 15 April 2006

View article titled, Antitumor activity of a new synthetic camptothecin with the open lacton ring.

Journal Articles

Complete Protection by High-Dose Dexamethasone against the Hepatotoxicity of the Novel Antitumor Drug Yondelis (ET-743) in the Rat

Sarah Donald, Richard D. Verschoyle, Peter Greaves, Timothy W. Gant, Tina Colombo, Marco Zaffaroni, Roberta Frapolli, Massimo Zucchetti, Maurizio D’Incalci, Daniela Meco, Riccardo Riccardi, Luis Lopez-Lazaro, Jose Jimeno, Andreas J. Gescher

Cancer Res (2003) 63 (18): 5902–5908.

Published: 01 October 2003

View article titled, Complete Protection by High-Dose Dexamethasone against the Hepatotoxicity of the Novel Antitumor Drug Yondelis (ET-743) in the Rat

NARROW

Abstract 7199: The retinoid X receptor (RXR) agonist IRX4204 potentiates the efficacy of trabectedin and pioglitazone in myxoid liposarcoma preclinical models

Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy

Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models

Abstract 2743: Accumulation of predicted neoantigens by MMR deficiency triggered by temozolomide treatment of human colorectal cancer

Abstract 5723: Inactivation of DNA repair triggers neoantigen generation and impairs tumor growth

Abstract 3764: Trabectedin activity in patient-derived mesothelioma xenografts

Abstract 1284: Lurbinectedin reduces tumor-associated macrophages and the production of inflammatory cytokines, chemokines, and angiogenic factors in preclinical models

Abstract 4821: The WEE1 inhibitor AZD-1775 has synergic activity with trabectedin or lurbinectedin in ovarian cancer cells

Abstract 1183: PPARgamma agonist promotes adipocytic differentiation and potentiates the activity of trabectedin in myxoid liposarcoma

Abstract 3526: OTX015 effects in triple-negative breast cancer (TNBC) models are independent of hypoxia conditions and synergistic with other anticancer agents

Abstract 3289: PTX-008, a dual inhibitor of angiogenesis and tumor cell proliferation, potentiates the antineoplastic activity of targeted therapies in human tumor models

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

Abstract #2679: Mechanism of action and antitumor activity of PM01183

The effect of vandetanib on tumor vasculature remodeling and paclitaxel uptake in a xenograft model of ovarian carcinoma

Biological Properties of IDN5174, a New Synthetic Camptothecin with the Open Lactone Ring

Antitumor activity of a new synthetic camptothecin with the open lacton ring.

Complete Protection by High-Dose Dexamethasone against the Hepatotoxicity of the Novel Antitumor Drug Yondelis (ET-743) in the Rat

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