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Journal Articles

Abstract 1305: Comparison of HPV-DNA testing to PET-CT imaging as prognostic test following definitive treatment for cervical cancer: A retrospective proof-of-concept study

Cameron Huddleston, Aya Bou Fakhreddine, Stephanie Stroever, Robert Young, Naresh Sah, Komaraiah Palle, Mark Reedy
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1305.
https://doi.org/10.1158/1538-7445.AM2024-1305
Published: 22 March 2024
View article titled, Abstract 1305: Comparison of HPV-DNA testing to PET-CT imaging as prognostic test following definitive treatment for cervical cancer: A retrospective proof-of-concept study
Journal Articles

Abstract 3703: Utility of circulating tumor DNA (ctDNA) from cerebrospinal fluid (CSF) for prognosis of patients with recurrent high grade glioma

Bridget M. Holle, Subhiksha Nandakumar, Christoph Kreitzer, Timothy Song, Marlene Tartaro, Charli Ann J. Hertz, Johnathan Rafailov, Carl Campos, Anne S. Reiner, Robert Young, Alicia Meng, Luca Pasquini, A. Rose Brannon, Nicholas D. Socci, Maria E. Arcila, David B. Solit, Michael F. Berger, Nikolaus Schultz, Ingo K. Mellinghoff, Alexandra M. Miller
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3703.
https://doi.org/10.1158/1538-7445.AM2024-3703
Published: 22 March 2024
View article titled, Abstract 3703: Utility of circulating tumor DNA (ctDNA) from cerebrospinal fluid (CSF) for prognosis of patients with recurrent high grade glioma
Journal Articles

Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation

Ian C. Henrich, Kanika Jain, Robert Young, Laura Quick, Jarrett M. Lindsay, Daniel H. Park, Andre M. Oliveira, Gerd A. Blobel, Margaret M. Chou
Journal: Cancer Research
Cancer Res (2021) 81 (8): 2171–2183.
https://doi.org/10.1158/0008-5472.CAN-20-1458
Published: 15 April 2021
View article titled, Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation
Open the PDF for Ubiquitin-Specific Protease 6 Functions as a Tumor Suppressor in Ewing Sarcoma through Immune Activation in another window
Includes: Supplementary data
Journal Articles

Abstract CT252: A dose escalation phase I study of concurrent GDC-0084 with radiation therapy for patients with solid tumor brain metastases or leptomeningeal metastases harboring PI3K pathway mutations

T. Jonathan Yang, Zhigang Zhang, Robert Young, James S. Garner, Jeremy Simpson, Adrienne Boire, Michael Offin, Eli Diamond
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT252.
https://doi.org/10.1158/1538-7445.AM2020-CT252
Published: 15 August 2020
View article titled, Abstract CT252: A dose escalation phase I study of concurrent GDC-0084 with radiation therapy for patients with solid tumor brain metastases or leptomeningeal metastases harboring PI3K pathway mutations
Journal Articles

Abstract 4649: Duplex Sequencing detects rare subclonal variants that mark early carcinogenesis and preneoplastic clonal evolution

Charles C. Valentine, Mark Fielden, Robert Young, Jake Higgins, Lindsey Williams, Tan Li, Rohan Kulkarni, Sheroy Minocherhomji, Rosana Risques, Patrick Danaher, Jesse Salk
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4649.
https://doi.org/10.1158/1538-7445.AM2019-4649
Published: 01 July 2019
View article titled, Abstract 4649: Duplex Sequencing detects rare subclonal variants that mark early carcinogenesis and preneoplastic clonal evolution
Journal Articles

Abstract 4705: CTLA4 blockade with HER2-directed therapy (H) yields clinical benefit in women undergoing radiation therapy (RT) for HER2-positive (HER2+) breast cancer brain metastases (BCBM)

Heather McArthur, Kathryn Beal, Darragh Halpenny, Micaela Henrich, Shanu Modi, Sujata Patil, Robert Young, Thomas Kaley, Taha Merghoub, Christopher Barker, Phillip Wong, Nicola Hamilton, Clifford Hudis, Jedd Wolchok, Larry Norton
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4705.
https://doi.org/10.1158/1538-7445.AM2017-4705
Published: 01 July 2017
View article titled, Abstract 4705: CTLA4 blockade with HER2-directed therapy (H) yields clinical benefit in women undergoing radiation therapy (RT) for HER2-positive (HER2+) breast cancer brain metastases (BCBM)
Journal Articles

Abstract LB-302: Potential role of larotrectinib (LOXO-101), a selective pan-TRK inhibitor, in NTRK fusion-positive recurrent glioblastoma

Alison M. Schram, Barry S. Taylor, Jaclyn F. Hechtman, Ryma Benayed, Lu Wang, Bethany Hanusch, Robert Young, Christian Grommes, Nora Ku, David M. Hyman, Thomas Kaley, Alexander Drilon
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-302.
https://doi.org/10.1158/1538-7445.AM2017-LB-302
Published: 01 July 2017
View article titled, Abstract LB-302: Potential role of larotrectinib (LOXO-101), a selective pan-TRK inhibitor, in NTRK fusion-positive recurrent glioblastoma
Journal Articles

Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis

Laura Quick, Robert Young, Ian C. Henrich, Xiaoke Wang, Yan W. Asmann, Andre M. Oliveira, Margaret M. Chou
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5337–5347.
https://doi.org/10.1158/0008-5472.CAN-15-2391
Published: 15 September 2016
View article titled, Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis
Open the PDF for Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 1498: Feasibility of 2-hydroxyglutarate 1H-MR spectroscopy for routine clinical glioma imaging

Macarena I. de la Fuente, Robert Young, Jennifer Rubel, Jamie Tisnado, Samuel Briggs, Andrei I. Holodny, Joseph Deasy, Lisa M. DeAngelis, Justin Cross, Ingo K. Mellinghoff, Sunitha Thakur
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1498.
https://doi.org/10.1158/1538-7445.AM2015-1498
Published: 01 August 2015
View article titled, Abstract 1498: Feasibility of 2-hydroxyglutarate 1H-MR spectroscopy for routine clinical glioma imaging
Journal Articles

Abstract 486: BET protein inhibition by JQ1 blocks EWS-FLI1 activity in Ewing sarcoma

Krista L. Bledsoe, Aaron Stonestrom, Stephan Kadauke, Laura Quick, Robert Young, Gerd A. Blobel, Margaret M. Chou
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 486.
https://doi.org/10.1158/1538-7445.AM2015-486
Published: 01 August 2015
View article titled, Abstract 486: BET protein inhibition by JQ1 blocks EWS-FLI1 activity in Ewing sarcoma
Journal Articles

Abstract 2902: The effectiveness of autophagy inhibition in sensitizing triple-negative breast cancer cells to chemotherapy

Svetlana Bortnik, Suganthi Chittaranjan, Jing Xu, Wieslawa H. Dragowska, Jianghong An, Adrienne Kyle, Nancy E. Go, Lubomir Vezenkov, Courtney Choutka, Amy Leung, Suzana Kovacic, Damien Bosc, Karen Gelmon, Marcel Bally, Steven Jones, Robert Young, Sharon Gorski
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2902.
https://doi.org/10.1158/1538-7445.AM2015-2902
Published: 01 August 2015
View article titled, Abstract 2902: The effectiveness of autophagy inhibition in sensitizing triple-negative breast cancer cells to chemotherapy
Journal Articles

Abstract #108: Chromosome 15q25 locus associated with lung function but not nicotine addiction in lung cancer patients

Robert Young, Raewyn Hopkins, Bryan Hay, Gregory Gamble
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 108.
Published: 01 May 2009
View article titled, Abstract #108: Chromosome 15q25 locus associated with lung function but not nicotine addiction in lung cancer patients
Journal Articles

A gene based risk score for smokers and ex-smokers identifies those most susceptible to lung cancer.

Robert Young, Raewyn Hopkins, Bryan Hay, Peter Black, Micheal Epton, Gregory Gamble
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3128.
Published: 01 May 2008
View article titled, A gene based risk score for smokers and ex-smokers identifies those most susceptible to lung cancer.
Journal Articles

A gene based risk score identifies smokers and ex-smokers at high risk of developing lung cancer: validation in a prospective study

Robert Young, Raewyn Hopkins, Bryan Hay, Gregory Gamble, Heather Gardner, Richard Sullivan
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-12.
Published: 01 May 2008
View article titled, A gene based risk score identifies smokers and ex-smokers at high risk of developing lung cancer: validation in a prospective study