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Robert M. Hoffman
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Journal Articles

Abstract 1795: Tumor-targeting Salmonella A1-R selectively delivers recombinant methioninase and inhibits syngeneic-cancer mouse models

Yutaro Kubota, Yusuke Aoki, Noriyuki Masaki, Koya Obara, Sei Morinaga, Kohei Mizuta, Motokazu Sato, Ming Zhao, Qinghong Han, Bouvet Michael, Takuya Tsunoda, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1795.
https://doi.org/10.1158/1538-7445.AM2024-1795
Published: 22 March 2024
View article titled, Abstract 1795: Tumor-targeting <em>Salmonella</em> A1-R selectively delivers recombinant methioninase and inhibits syngeneic-cancer mouse models
Journal Articles

Abstract 3896: Alteration of malignancy and histone-H3 lysine-methylation status in osteosarcoma cells which acquire methotrexate resistance in vitro

Yusuke Aoki, Yasunori Tome, Hiromichi Oshiro, Ryo Katsuki, Kohei Mizuta, Kotaro Nishida, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3896.
https://doi.org/10.1158/1538-7445.AM2023-3896
Published: 04 April 2023
View article titled, Abstract 3896: Alteration of malignancy and histone-H3 lysine-methylation status in osteosarcoma cells which acquire methotrexate resistance <em>in vitro</em>
Journal Articles

Abstract 2380: Fluorescence labeling of human gastric cancer using novel tumor specific near infrared labeled antibodies

Kristin E. Cox, Michael A. Turner, Siamak Amirfakhri, Thinzar M. Lwin, Pradipta Ghosh, Marygorret Obonyo, Kaitlyn M. Kelly, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2380.
https://doi.org/10.1158/1538-7445.AM2023-2380
Published: 04 April 2023
View article titled, Abstract 2380: Fluorescence labeling of human gastric cancer using novel tumor specific near infrared labeled antibodies
Journal Articles

Abstract 1658: Anti-CEACAM binding protein for fluorescence visualization of primary colon cancer in patient-derived orthotopic xenograph mouse models

Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Verena Schmitt, Gunther Wennemuth, Alexej Schmidt, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1658.
https://doi.org/10.1158/1538-7445.AM2020-1658
Published: 15 August 2020
View article titled, Abstract 1658: Anti-CEACAM binding protein for fluorescence visualization of primary colon cancer in patient-derived orthotopic xenograph mouse models
Journal Articles

Abstract 1661: Temozolomide suppresses a doxorubicin resistant follicular dendritic cell sarcoma in a patient derived orthotopic xenograft mouse model

Hiromichi Oshiro, Yasunori Tome, Robert M. Hoffman, Kotaro Nishida
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1661.
https://doi.org/10.1158/1538-7445.AM2020-1661
Published: 15 August 2020
View article titled, Abstract 1661: Temozolomide suppresses a doxorubicin resistant follicular dendritic cell sarcoma in a patient derived orthotopic xenograft mouse model
Journal Articles

Abstract 2791: mTOR inhibitor and VEGFR inhibitor combination therapy regress a doxorubicin resistant osteosarcoma in a patient-derived orthotopic xenograft model and in vivo angiogenesis assay model

Hiromichi Oshiro, Yasunori Tome, Robert M. Hoffman, Kotaro Nishida
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2791.
https://doi.org/10.1158/1538-7445.AM2020-2791
Published: 15 August 2020
View article titled, Abstract 2791: mTOR inhibitor and VEGFR inhibitor combination therapy regress a doxorubicin resistant osteosarcoma in a patient-derived orthotopic xenograft model and <em>in vivo</em> angiogenesis assay model
Journal Articles

Abstract 2786: Color-coded fluorescence-guided surgery in a patient-derived orthotopic xenograft (PDOX) nude mouse model of colon-cancer liver metastasis with ICG and a fluorescent antibody

Hiroto Nishino, Hannah M. Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Jun Yamamoto, Yoshihiko Tashiro, Robert M. Hoffman, Michael Bouvet
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2786.
https://doi.org/10.1158/1538-7445.AM2020-2786
Published: 15 August 2020
View article titled, Abstract 2786: Color-coded fluorescence-guided surgery in a patient-derived orthotopic xenograft (PDOX) nude mouse model of colon-cancer liver metastasis with ICG and a fluorescent antibody
Journal Articles

Abstract 1148: Recombinant cancer-stromal cells Identified in the metastatic tumor microenvironment By color-coded imaging

Miki Nakamura, Atsushi Suetsugu, Kana Matsuura, Tomoyuki Satake, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1148.
https://doi.org/10.1158/1538-7445.AM2019-1148
Published: 01 July 2019
View article titled, Abstract 1148: Recombinant cancer-stromal cells Identified in the metastatic tumor microenvironment By color-coded imaging
Journal Articles

Abstract 1143: The circulating tumor cell (CTC) microenvironment visualized by color coded imaging

Atsushi Suetsugu, Tomoyuki Satake, Miki Nakamura, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1143.
https://doi.org/10.1158/1538-7445.AM2019-1143
Published: 01 July 2019
View article titled, Abstract 1143: The circulating tumor cell (CTC) microenvironment visualized by color coded imaging
Journal Articles

Abstract 1445: Metastasis-resistant fatty liver induced by a choline-deficient diet

Miki Nakamura, Atsushi Suetsugu, Tomoyuki Satake, Kosuke Hasegawa, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1445.
https://doi.org/10.1158/1538-7445.AM2018-1445
Published: 01 July 2018
View article titled, Abstract 1445: Metastasis-resistant fatty liver induced by a choline-deficient diet
Journal Articles

Abstract 3110: Heterokaryon formation and nuclear fusion of hybridizing cancer cells visualized in real time by color-coded imaging

Atsushi Suetsugu, Takuro Matsumoto, Kousuke Hasegawa, Miki Nakamura, Takahiro Kunisada, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3110.
https://doi.org/10.1158/1538-7445.AM2018-3110
Published: 01 July 2018
View article titled, Abstract 3110: Heterokaryon formation and nuclear fusion of hybridizing cancer cells visualized in real time by color-coded imaging
Journal Articles

Abstract 1980: Fusion of cancer and stromal cells imaged by color -coded imaging of metasasis

Miki Nakamura, Atsushi Suetsugu, Kousuke Hasegawa, Takuro Matsumoto, Hitomi Aoki, Takahiro Kunisada, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1980.
https://doi.org/10.1158/1538-7445.AM2017-1980
Published: 01 July 2017
View article titled, Abstract 1980: Fusion of cancer and stromal cells imaged by color -coded imaging of metasasis
Journal Articles

Abstract 3729: Tumor-specific antibody labeling of pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model using a fluorescent humanized anti-CEA antibody

Thinzar Lwin, Takashi Murakami, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3729.
https://doi.org/10.1158/1538-7445.AM2017-3729
Published: 01 July 2017
View article titled, Abstract 3729: Tumor-specific antibody labeling of pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model using a fluorescent humanized anti-CEA antibody
Journal Articles

Abstract 1872: Fluorescence-guided surgery in the tumor microenvironment in a syngeneic mouse model of EL-4 lymphoma

Kosuke Hasegawa, Atsushi Suetsugu, Miki Nakamura, Takuro Matsumoto, Takahiro Kunisada, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1872.
https://doi.org/10.1158/1538-7445.AM2017-1872
Published: 01 July 2017
View article titled, Abstract 1872: Fluorescence-guided surgery in the tumor microenvironment in a syngeneic mouse model of EL-4 lymphoma
Journal Articles

Abstract 2874: Inhibition of tumor angiogenesis by Salmonella typhimurium A1-R in the in vivo Gelfoam color-coded imaging assay

Tasuku Kiyuna, Yasunori Tome, Takashi Murakami, Ming Zhao, Fuminori Kanaya, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2874.
https://doi.org/10.1158/1538-7445.AM2017-2874
Published: 01 July 2017
View article titled, Abstract 2874: Inhibition of tumor angiogenesis by <em>Salmonella typhimurium</em> A1-R in the <em>in vivo</em> Gelfoam color-coded imaging assay
Journal Articles

Abstract 5900: Transforming growth factor-beta (TGF-β) inhibitor modulates cancer stroma in a pancreatic cancer orthotopic mouse model

Takashi Murakami, Yukihiko Hiroshima, Kentaro Miyake, Tasuku Kiyuna, Ho Kyoung Hwang, Kei Kawaguchi, Jonathan C. DeLong, Thinzer M. Lwin, Kentaro Igarashi, Ryusei Matsuyama, Ryutaro Mori, Takafumi Kumamoto, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5900.
https://doi.org/10.1158/1538-7445.AM2017-5900
Published: 01 July 2017
View article titled, Abstract 5900: Transforming growth factor-beta (TGF-β) inhibitor modulates cancer stroma in a pancreatic cancer orthotopic mouse model
Journal Articles

Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Tasuku Kiyuna, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1408.
https://doi.org/10.1158/1538-7445.AM2016-1408
Published: 15 July 2016
View article titled, Abstract 1408: Tumor-targeting Salmonella typhimurium A1-R promotes CD8+ T cell infiltration in pancreatic cancer in an orthotopic syngeneic mouse model
Journal Articles

Abstract 4221: Imaging formation of the tumor microenvironment in orthotopic liver tumors in red fluorescent protein (RFP) transgenic nude mice

Atsushi Suetsugu, Yukihiko Hiroshima, Takuro Matsumoto, Kosuke Hasegawa, Miki Nakamura, Masahito Shimizu, Shigetoyo Saji, Hisataka Moriwaki, Michael Bouvet, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4221.
https://doi.org/10.1158/1538-7445.AM2016-4221
Published: 15 July 2016
View article titled, Abstract 4221: Imaging formation of the tumor microenvironment in orthotopic liver tumors in red fluorescent protein (RFP) transgenic nude mice
Journal Articles

Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery

Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, MIchael Bouvet, Itaru Endo, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4220.
https://doi.org/10.1158/1538-7445.AM2016-4220
Published: 15 July 2016
View article titled, Abstract 4220: Tumor-targeting Salmonella typhimurium A1-R efficacy on colon cancer liver metastasis alone and in combination with fluorescence-guided surgery
Journal Articles

Abstract 4111: Imaging of colon cancer-cell mitosis within liver metastasis in nude mice

Kosuke Hasegawa, Atsushi Suetsugu, Miki Nakamura, Takuro Matsumoto, Hitomi Aoki, Takahiro Kunisada, Masahito Shimizu, Robert M. Hoffman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4111.
https://doi.org/10.1158/1538-7445.AM2016-4111
Published: 15 July 2016
View article titled, Abstract 4111: Imaging of colon cancer-cell mitosis within liver metastasis in nude mice