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Robert L. Dedrick
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Journal Articles

Allometric scaling of STEALTH® liposomal anticancer agents

Free
William C. Zamboni, Holly Whitner, Douglas M. Potter, Ramesh K. Ramanathan, Sandra Strychor, Margaret E. Tonda, Barbara Stewart, Nishit Modi, Charles Engbers, Robert L. Dedrick
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 326.
Published: 01 May 2005
View articletitled, Allometric scaling of STEALTH® liposomal anticancer agents
Journal Articles

A Pharmacokinetic Model of Topotecan Clearance from Plasma and Cerebrospinal Fluid

Free
Cynthia Sung, Susan M. Blaney, Diane E. Cole, Frank M. Balis, Robert L. Dedrick
Journal: Cancer Research
Cancer Res (1994) 54 (19): 5118–5122.
Published: 01 October 1994
View articletitled, A Pharmacokinetic Model of Topotecan Clearance from Plasma and Cerebrospinal Fluid
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Journal Articles

Monoclonal Antibody Delivery to Intraperitoneal Tumors in Rats: Effects of Route of Administration and Intraperitoneal Solution Osmolality

Free
Michael F. Flessner, Robert L. Dedrick
Journal: Cancer Research
Cancer Res (1994) 54 (16): 4376–4384.
Published: 01 August 1994
View articletitled, Monoclonal Antibody Delivery to Intraperitoneal Tumors in Rats: Effects of Route of Administration and Intraperitoneal Solution Osmolality
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Journal Articles

Streptavidin Distribution in Metastatic Tumors Pretargeted with a Biotinylated Monoclonal Antibody: Theoretical and Experimental Pharmacokinetics

Free
Cynthia Sung, William W. van Osdol, Tsuneo Saga, Ronald D. Neumann, Robert L. Dedrick, John N. Weinstein
Journal: Cancer Research
Cancer Res (1994) 54 (8): 2166–2175.
Published: 01 April 1994
View articletitled, Streptavidin Distribution in Metastatic Tumors Pretargeted with a Biotinylated Monoclonal Antibody: Theoretical and Experimental Pharmacokinetics
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Journal Articles

Pharmacokinetics and Toxicology of Immunotoxins Administered into the Subarachnoid Space in Nonhuman Primates and Rodents

Free
Karin Muraszko, Cynthia Sung, Stuart Walbridge, Larry Greenfield, Robert L. Dedrick, Edward H. Oldfield, Richard J. Youle
Journal: Cancer Research
Cancer Res (1993) 53 (16): 3752–3757.
Published: 01 August 1993
View articletitled, Pharmacokinetics and Toxicology of Immunotoxins Administered into the Subarachnoid Space in Nonhuman Primates and Rodents
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Journal Articles

The Spatial Distribution of Immunotoxins in Solid Tumors: Assessment by Quantitative Autoradiography

Free
Cynthia Sung, Robert L. Dedrick, Walter A. Hall, Patricia A. Johnson, Richard J. Youle
Journal: Cancer Research
Cancer Res (1993) 53 (9): 2092–2099.
Published: 01 May 1993
View articletitled, The Spatial Distribution of Immunotoxins in Solid Tumors: Assessment by Quantitative Autoradiography
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Journal Articles

Carcinogenic Potency of Alkylating Agents in Rodents and Humans

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Robert L. Dedrick, Paul F. Morrison
Journal: Cancer Research
Cancer Res (1992) 52 (9): 2464–2467.
Published: 01 May 1992
View articletitled, Carcinogenic Potency of Alkylating Agents in Rodents and Humans
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Journal Articles

Predicted and Observed Effects of Antibody Affinity and Antigen Density on Monoclonal Antibody Uptake in Solid Tumors

Free
Cynthia Sung, Ty R. Shockley, Paul F. Morrison, Harold F. Dvorak, Martin L. Yarmush, Robert L. Dedrick
Journal: Cancer Research
Cancer Res (1992) 52 (2): 377–384.
Published: 01 January 1992
View articletitled, Predicted and Observed Effects of Antibody Affinity and Antigen Density on Monoclonal Antibody Uptake in Solid Tumors
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Journal Articles

A Quantitative Analysis of Tumor specific Monoclonal Antibody Uptake by Human Melanoma Xenografts: Effects of Antibody Immunological Properties and Tumor Antigen Expression Levels

Free
Ty R. Shockley, Ke Lin, Cynthia Sung, Janice A. Nagy, Ronald G. Tompkins, Robert L. Dedrick, Harold F. Dvorak, Martin L. Yarmush
Journal: Cancer Research
Cancer Res (1992) 52 (2): 357–366.
Published: 01 January 1992
View articletitled, A Quantitative Analysis of Tumor specific Monoclonal Antibody Uptake by Human Melanoma Xenografts: Effects of Antibody Immunological Properties and Tumor Antigen Expression Levels
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Journal Articles

Pharmacokinetic Analysis of Immunotoxin Uptake in Solid Tumors: Role of Plasma Kinetics, Capillary Permeability, and Binding

Free
Cynthia Sung, Richard J. Youle, Robert L. Dedrick
Journal: Cancer Research
Cancer Res (1990) 50 (22): 7382–7392.
Published: 01 November 1990
View articletitled, Pharmacokinetic Analysis of Immunotoxin Uptake in Solid Tumors: Role of Plasma Kinetics, Capillary Permeability, and Binding
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Journal Articles

Lack of in Vitro Synergy between Etoposide and cis-Diammine-dichloroplatinum(II)

Free
Chun-Ming Tsai, Adi F. Gazdar, David J. Venzon, Seth M. Steinberg, Robert L. Dedrick, James L. Mulshine, Barnett S. Kramer
Journal: Cancer Research
Cancer Res (1989) 49 (9): 2390–2397.
Published: 01 May 1989
View articletitled, Lack of in Vitro Synergy between Etoposide and cis-Diammine-dichloroplatinum(II)
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Journal Articles

Reduced Systemic Drug Exposure by Combining Intraarterial cis-Diamminedichloroplatinum(II) with Hemodialysis of Regional Venous Drainage

Free
Edward H. Oldfield, W. Craig Clark, Robert L. Dedrick, Merrill J. Egorin, Howard A. Austin, Hetty D. DeVroom, Kathleen M. Joyce, John L. Doppman
Journal: Cancer Research
Cancer Res (1987) 47 (7): 1962–1967.
Published: 01 April 1987
View articletitled, Reduced Systemic Drug Exposure by Combining Intraarterial cis-Diamminedichloroplatinum(II) with Hemodialysis of Regional Venous Drainage
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Journal Articles

Portal Levels and Hepatic Clearance of 5-Fluorouracil after Intraperitoneal Administration in Humans

Free
James L. Speyer, Paul H. Sugarbaker, Jerry M. Collins, Robert L. Dedrick, Raymond W. Klecker, Jr., Charles E. Myers
Journal: Cancer Research
Cancer Res (1981) 41 (5): 1916–1922.
Published: 01 May 1981
View articletitled, Portal Levels and Hepatic Clearance of 5-Fluorouracil after Intraperitoneal Administration in Humans
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Journal Articles

High-Volume Intraperitoneal Chemotherapy with Methotrexate in Patients with Cancer

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Roy B. Jones, Jerry M. Collins, Charles E. Myers, Ada E. Brooks, Susan M. Hubbard, James E. Balow, Murray F. Brennan, Robert L. Dedrick, Vincent T. DeVita
Journal: Cancer Research
Cancer Res (1981) 41 (1): 55–59.
Published: 01 January 1981
View articletitled, High-Volume Intraperitoneal Chemotherapy with Methotrexate in Patients with Cancer
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Journal Articles

Phase I and Pharmacological Studies of 5-Fluorouracil Administered Intraperitoneally

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James L. Speyer, Jerry M. Collins, Robert L. Dedrick, Murray F. Brennan, Alan R. Buckpitt, Harold Londer, Vincent T. DeVita, Jr., Charles E. Myers
Journal: Cancer Research
Cancer Res (1980) 40 (3): 567–572.
Published: 01 March 1980
View articletitled, Phase I and Pharmacological Studies of 5-Fluorouracil Administered Intraperitoneally
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Journal Articles

Distribution and Disposition of Platinum following Intravenous Administration of cis-Diamminedichloroplatinum(II) (NSC 119875) to Dogs

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Charles L. Litterst, Theodore E. Gram, Robert L. Dedrick, Andre F. Leroy, Anthony M. Guarino
Journal: Cancer Research
Cancer Res (1976) 36 (7_Part_1): 2340–2344.
Published: 01 July 1976
View articletitled, Distribution and Disposition of Platinum following Intravenous Administration of cis-Diamminedichloroplatinum(II) (NSC 119875) to Dogs
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