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Robert I. Glazer
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Journal Articles

Abstract 293: Distinctive roles of mammary adipomes in breast cancer progression: Insights from functional analysis and differential gene expression

Free
Hariprasad Thangavel, Kezia Lizardo, Robert I. Glazer, Jyothi F. Nagajyothi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 293.
https://doi.org/10.1158/1538-7445.AM2024-293
Published: 22 March 2024
View articletitled, Abstract 293: Distinctive roles of mammary adipomes in breast cancer progression: Insights from functional analysis and differential gene expression
Journal Articles

Abstract 394: LXR agonist N,N-dimethyl-3-β-hydroxy-cholenamide, DMHCA, reduces ErbB2-dependent tumorigenesis and immune tolerance in a conditional model of mammary fibrosis

Free
Robert I. Glazer, Gao Sheng, Hongyan Yuan, Suman Ranjit, Jin Lu, Xun Lu, Moshe Levi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 394.
https://doi.org/10.1158/1538-7445.AM2020-394
Published: 15 August 2020
View articletitled, Abstract 394: LXR agonist N,N-dimethyl-3-β-hydroxy-cholenamide, DMHCA, reduces ErbB2-dependent tumorigenesis and immune tolerance in a conditional model of mammary fibrosis
Journal Articles

Abstract 5892: Induction of stromal fibrosis accelerates tumorigenesis in NeuT mice

Free
Robert I. Glazer, Hongyan Yuan, Lu Jin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5892.
https://doi.org/10.1158/1538-7445.AM2017-5892
Published: 01 July 2017
View articletitled, Abstract 5892: Induction of stromal fibrosis accelerates tumorigenesis in NeuT mice
Journal Articles

PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation

Free
Hongyan Yuan, Jin Lu, Junfeng Xiao, Geeta Upadhyay, Rachel Umans, Bhaskar Kallakury, Yuhzi Yin, Michael E. Fant, Levy Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4349–4361.
https://doi.org/10.1158/0008-5472.CAN-13-0322
Published: 15 July 2013
View articletitled, PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation
Open the PDF for PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation in another window
Includes: Supplementary data
Journal Articles

Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk.

Free
Sarah A. Dabydeen, Weisheng Wang, Edgar S. Diaz-Cruz, Levy Kopelovich, Robert I. Glazer, Priscilla A. Furth
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 197.
https://doi.org/10.1158/1538-7445.AM2013-197
Published: 15 April 2013
View articletitled, Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk.
Journal Articles

Abstract 1385: PPARδ promotes mammary tumorigenesis through mTOR activation.

Free
Robert I. Glazer, Hongyan Yuan, Geeta Upadhyay, Yuzhi Yin, Levy Kopelovich
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1385.
https://doi.org/10.1158/1538-7445.AM2013-1385
Published: 15 April 2013
View articletitled, Abstract 1385: PPARδ promotes mammary tumorigenesis through mTOR activation.
Journal Articles

Abstract 4214: Stem cell antigen-1 (Sca1) modulates PI3K/PTEN signaling and mammary tumor cell survival

Free
Geeta Upadhyay, Claire Pollock, Yuzhi Yin, Hongyan Yuan, Levi Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4214.
https://doi.org/10.1158/1538-7445.AM10-4214
Published: 15 April 2010
View articletitled, Abstract 4214: Stem cell antigen-1 (Sca1) modulates PI3K/PTEN signaling and mammary tumor cell survival
Journal Articles

Abstract 3263: Acceleration of mammary tumorigenesis by PDK1 and peroxisome proliferator-activated receptorδ

Free
Claire B. Pollock, Yuzhi Yin, Hongyan Yuan, Xiao Zeng, Sruthi King, Levy Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3263.
https://doi.org/10.1158/1538-7445.AM10-3263
Published: 15 April 2010
View articletitled, Abstract 3263: Acceleration of mammary tumorigenesis by PDK1 and peroxisome proliferator-activated receptorδ
Journal Articles

Abstract 945: Sca-1 deficiency enhances the chemopreventive activity of a peroxisome proliferator-activated receptorγ (PPARγ) agonist

Free
Hongyan Yuan, Geeta Upadhyay, Yuzhi Yin, Claire Pollock, Levy Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 945.
https://doi.org/10.1158/1538-7445.AM10-945
Published: 15 April 2010
View articletitled, Abstract 945: Sca-1 deficiency enhances the chemopreventive activity of a peroxisome proliferator-activated receptorγ (PPARγ) agonist
Journal Articles

Inhibition of Peroxisome Proliferator-Activated Receptor γ Increases Estrogen Receptor–Dependent Tumor Specification

Free
Yuzhi Yin, Hongyan Yuan, Xiao Zeng, Levy Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2009) 69 (2): 687–694.
https://doi.org/10.1158/0008-5472.CAN-08-2446
Published: 15 January 2009
View articletitled, Inhibition of Peroxisome Proliferator-Activated Receptor γ Increases Estrogen Receptor–Dependent Tumor Specification
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Includes: Supplementary data
Journal Articles

Modulation of Stem Cell Antigen (Sca-1) Expression by the PDK1 and Stat Pathways

Free
Yuzhi Yin, Sruthi T. Kristipati, Hongyan Yuan, Levy Kopelovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 240.
Published: 15 April 2006
View articletitled, Modulation of Stem Cell Antigen (Sca-1) Expression by the PDK1 and Stat Pathways
Journal Articles

Identification of conserved gene expression features across human and murine mammary tumors

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Jason I. Herschkowitz, Karl Simin, Victor J. Weigman, Igor Mikaelian, Zhiyuan Hu, Karen E. Rasmussen, Laundette P. Jones, Shahin Assefnia, Subhashini Chandrasekharan, Michael G. Backlund, Yuzhi Yin, Robert I. Glazer, Powel H. Brown, Jeffrey E. Green, Levy Kopelovich, Priscilla A. Furth, Juan P. Palazzo, Olufunmilayo I. Olopade, Philip S. Bernard, Gary A. Churchill, Terry Van Dyke, Charles M. Perou
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1136–1137.
Published: 15 April 2006
View articletitled, Identification of conserved gene expression features across human and murine mammary tumors
Journal Articles

Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development

Free
Erich Koller, Stephanie Propp, Hong Zhang, Chenguang Zhao, Xiaokun Xiao, MingYi Chang, Scott A. Hirsch, Peter J. Shepard, Seongjoon Koo, Cain Murphy, Robert I. Glazer, Nicholas M. Dean
Journal: Cancer Research
Cancer Res (2006) 66 (4): 2059–2066.
https://doi.org/10.1158/0008-5472.CAN-05-1531
Published: 17 February 2006
View articletitled, Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development
Open the PDF for Use of a Chemically Modified Antisense Oligonucleotide Library to Identify and Validate Eg5 (Kinesin-Like 1) as a Target for Antineoplastic Drug Development in another window
Includes: Supplementary data
Journal Articles

Peroxisome Proliferator-Activated Receptor δ and γ Agonists Differentially Alter Tumor Differentiation and Progression during Mammary Carcinogenesis

Free
Yuzhi Yin, Robert G. Russell, Luis E. Dettin, Renkui Bai, Zhi-Liang Wei, Alan P. Kozikowski, Levy Kopleovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3950–3957.
https://doi.org/10.1158/0008-5472.CAN-04-3990
Published: 02 May 2005
View articletitled, Peroxisome Proliferator-Activated Receptor δ and γ Agonists Differentially Alter Tumor Differentiation and Progression during Mammary Carcinogenesis
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Journal Articles

Inhibition of Eg5 (kinesin-like 1) with Antisense Oligonucleotides leads to cell-cycle arrest in G2/M and antitumor activity against xenograft tumors

Free
Stephanie S. Propp, Erich Koller, Ming Yi Chang, Robert I. Glazer, Scott Hirsch, Peter Shepard, Seongjoon Koo, Cain Murphy, Nicholas Dean
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1047.
Published: 01 May 2005
View articletitled, Inhibition of Eg5 (kinesin-like 1) with Antisense Oligonucleotides leads to cell-cycle arrest in G2/M and antitumor activity against xenograft tumors
Journal Articles

ErbB2 activation of Notch1 signaling in breast cancer

Free
Toshiyuki Sakamaki, Manran Liu, Sanjay Katiyar, Mahadev Rao, Shiguang Li, Yuzhi Yin, Luis E. Dettin, Richard G. Pestell, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 869.
Published: 01 May 2005
View articletitled, ErbB2 activation of Notch1 signaling in breast cancer
Journal Articles

PDK1 as a preferred target for sensitizing breast cancer cells to gemcitabine

Free
Ke Liang, Xiao Zeng, Robert I. Glazer, Weidong Jin, Gordon B. Mills, Zhen Fan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 890.
Published: 01 April 2004
View articletitled, PDK1 as a preferred target for sensitizing breast cancer cells to gemcitabine
Journal Articles

PPARγ and PPARδ agonists substantially increase the rate of tumor formation in progestin/DMBA mammary carcinogenesis in mice

Free
Yuzhi Yin, Robert G. Russell, Clint Grubbs, Levy Kopleovich, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1273–1274.
Published: 01 April 2004
View articletitled, PPARγ and PPARδ agonists substantially increase the rate of tumor formation in progestin/DMBA mammary carcinogenesis in mice
Journal Articles

Transformation of Mammary Epithelial Cells by 3-Phosphoinositide- dependent Protein Kinase-1 Activates β-Catenin and c-Myc, and Down-Regulates Caveolin-1

Free
Zhihui Xie, Xiao Zeng, Todd Waldman, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5370–5375.
Published: 18 September 2003
View articletitled, Transformation of Mammary Epithelial Cells by 3-Phosphoinositide- dependent Protein Kinase-1 Activates β-Catenin and c-Myc, and Down-Regulates Caveolin-1
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Journal Articles

Transformation of Mammary Epithelial Cells by 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) Is Associated with the Induction of Protein Kinase Cα

Free
Xiao Zeng, Hangmin Xu, Robert I. Glazer
Journal: Cancer Research
Cancer Res (2002) 62 (12): 3538–3543.
Published: 01 June 2002
View articletitled, Transformation of Mammary Epithelial Cells by 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) Is Associated with the Induction of Protein Kinase Cα
Open the PDF for Transformation of Mammary Epithelial Cells by 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) Is Associated with the Induction of Protein Kinase Cα in another window