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Robert H. Shoemaker
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Journal Articles

Abstract 6337: A novel PMS2 mutant Lynch syndrome mouse model for cancer prevention studies

Free
Kajal Biswas, Yurong Song, Vaishnavi Peddibhotla, Brandon Somerville, Mary Albaugh, Dillon Dierman, Rameesha Mustafa, Altaf Mohammed, Shyam K. Sharan, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6337.
https://doi.org/10.1158/1538-7445.AM2025-6337
Published: 21 April 2025
View articletitled, Abstract 6337: A novel PMS2 mutant Lynch syndrome mouse model for cancer prevention studies
Journal Articles

Abstract 3531: Development of a mRNA-LNP vaccine for Lynch syndrome

Free
Yuri Koboziev, Ligia A. Pinto, Robert H. Shoemaker, Jason D. Marshall
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3531.
https://doi.org/10.1158/1538-7445.AM2025-3531
Published: 21 April 2025
View articletitled, Abstract 3531: Development of a mRNA-LNP vaccine for Lynch syndrome
Journal Articles

Abstract 6343: Frameshift neoantigen-based vaccine testing in an intra-cecal implantation mouse model of Lynch syndrome

Free
Yurong Song, Brandon Somerville, Shaneen S. Baxter, Jason D. Marshall, Lei Wei, Chelsea Sanders, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Simone Difilippantonio, Ligia Pinto, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6343.
https://doi.org/10.1158/1538-7445.AM2025-6343
Published: 21 April 2025
View articletitled, Abstract 6343: Frameshift neoantigen-based vaccine testing in an intra-cecal implantation mouse model of Lynch syndrome
Journal Articles

Abstract 4778: Development of self-amplifying RNA vaccines targeting prostate tissue-restricted and tumor-associated antigens

Free
Robert H. Shoemaker, Jesse H. Erasmus, Peter Berglund, Jason D. Marshall, Yuri Koboziev, Bradley M. Beckman, Brian D. Cholewa, Steven G. Reed
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4778.
https://doi.org/10.1158/1538-7445.AM2024-4778
Published: 22 March 2024
View articletitled, Abstract 4778: Development of self-amplifying RNA vaccines targeting prostate tissue-restricted and tumor-associated antigens
Journal Articles

Abstract 1445: Emergence of frameshift mutations during tumorigenesis in VCMsh2 mouse model of Lynch syndrome

Free
Yurong Song, Lei Wei, Shaneen S. Baxter, Brandon Somerville, Holli Loomans-Kropp, Chelsea Sanders, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Qiang Hu, Song Liu, Alan Hutson, Simone Difilippantonio, Ligia Pinto, Steven M. Lipkin, Matthias Kloor, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1445.
https://doi.org/10.1158/1538-7445.AM2024-1445
Published: 22 March 2024
View articletitled, Abstract 1445: Emergence of frameshift mutations during tumorigenesis in VCMsh2 mouse model of Lynch syndrome
Journal Articles

Abstract 6518: Time course genomic characterization reveals progressive accumulation of mutations during tumor development in a Lynch syndrome mouse model

Free
Yurong Song, Shaneen Baxter, Lisheng Dai, Chelsea Sanders, Holli Loomans-Kropp, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Simone Difilippantonio, Ligia Pinto, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6518.
https://doi.org/10.1158/1538-7445.AM2023-6518
Published: 04 April 2023
View articletitled, Abstract 6518: Time course genomic characterization reveals progressive accumulation of mutations during tumor development in a Lynch syndrome mouse model
Journal Articles

Abstract 5562: Development of a TERT-specific peptide/adjuvant vaccine in C57BL/6 mice

Free
Jason D. Marshall, Yurong Song, Hamid Zarkesh, Rebecca L. Matthews, Chelsea Sanders, Simone Difilippantonio, Ligia A. Pinto, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5562.
https://doi.org/10.1158/1538-7445.AM2022-5562
Published: 15 June 2022
View articletitled, Abstract 5562: Development of a TERT-specific peptide/adjuvant vaccine in C57BL/6 mice
Journal Articles

Abstract 1618: Inhibition of lung tumorigenesis by a novel small molecule CA170 targeting the immune checkpoint protein VISTA

Free
Jing Pan, Yao Chen, Qi Zhang, Achia Khatun, Katie Palen, Li Wang, Chuanjia Yang, Bryon D. Johnson, Charles R. Myers, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Yian Wang, Weiguo Cui, Ming You
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1618.
https://doi.org/10.1158/1538-7445.AM2021-1618
Published: 01 July 2021
View articletitled, Abstract 1618: Inhibition of lung tumorigenesis by a novel small molecule CA170 targeting the immune checkpoint protein VISTA
Journal Articles

Abstract 4584: A novel combination of a multipeptide KRAS vaccine and an ACAT1 inhibitor to prevent lung cancer

Free
Jing Pan, Qi Zhang, Katie Palen, Bryon Johnson, Li Wang, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Yian Wang, Ming You
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4584.
https://doi.org/10.1158/1538-7445.AM2020-4584
Published: 15 August 2020
View articletitled, Abstract 4584: A novel combination of a multipeptide KRAS vaccine and an ACAT1 inhibitor to prevent lung cancer
Journal Articles

Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

Free
Laura Reyes Uribe, Wenhui Wu, Ozkan Gelincik, Prashant V. Bommi, Alejandro Francisco-Cruz, Luisa M. Solis, Patrick M. Lynch, Ramona Lim, Elena Stoffel, Priyanka Kanth, N. Jewel Samadder, Maureen E. Mork, Melissa W. Taggart, Ginger L. Milne, Lawrence J. Marnett, Lana Vornik, Diane D. Liu, Maria Revuelta, Kyle Chang, Y. Nancy You, Levy Kopelovich, Ignacio I. Wistuba, J. Jack Lee, Shizuko Sei, Robert H. Shoemaker, Eva Szabo, Ellen Richmond, Asad Umar, Marjorie Perloff, Powell H. Brown, Steven M. Lipkin, Eduardo Vilar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT111.
https://doi.org/10.1158/1538-7445.AM2020-CT111
Published: 15 August 2020
View articletitled, Abstract CT111: Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa
Journal Articles

Abstract 648: Effects of bazedoxifene and lapatinib in the prevention of estrogen receptor positive (ER+) and negative (ER-) mammary cancers

Free
Clinton J. Grubbs, Altaf Mohammed, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 648.
https://doi.org/10.1158/1538-7445.AM2019-648
Published: 01 July 2019
View articletitled, Abstract 648: Effects of bazedoxifene and lapatinib in the prevention of estrogen receptor positive (ER+) and negative (ER-) mammary cancers
Journal Articles

Abstract LB-173: Epitope mapping of mTERT for vaccine development

Free
Yurong Song, Jason Marshall, Sudipto Das, Thorkell Andresson, Amanda Corbel, Shizuko Sei, Robert H. Shoemaker, Ligia Pinto
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-173.
https://doi.org/10.1158/1538-7445.AM2018-LB-173
Published: 01 July 2018
View articletitled, Abstract LB-173: Epitope mapping of mTERT for vaccine development
Journal Articles

Abstract 4989: Efficacy of erlotinib and/or naproxen when administered by intermittent dosing schedules in the prevention of chemically induced urinary bladder cancers

Free
Altaf Mohammed, Mark S. Miller, Ronald A. Lubet, Chen Suen, Shizuko Sei, Robert H. Shoemaker, Clinton J. Grubbs
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4989.
https://doi.org/10.1158/1538-7445.AM2018-4989
Published: 01 July 2018
View articletitled, Abstract 4989: Efficacy of erlotinib and/or naproxen when administered by intermittent dosing schedules in the prevention of chemically induced urinary bladder cancers
Journal Articles

Abstract B48: Animal models in use by the NCI PREVENT Cancer Preclinical Drug Development Program

Free
Altaf Mohammed, Mark Steven Miller, Elizabeth Glaze, Romaine I. Fernando, Jennifer Fox, Ronald A. Lubet, Shizuko Sei, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): B48.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-B48
Published: 14 May 2018
View articletitled, Abstract B48: Animal models in use by the NCI PREVENT Cancer Preclinical Drug Development Program
Journal Articles

Abstract 1698: Immunoprevention of KRAS-driven lung adenocarcinoma by a multi-peptide KRAS vaccine

Free
Jing Pan, Qi Zhang, Shizuko Sei, Robert H. Shoemaker, Ronald A. Lubet, Yian Wang, Ming You
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1698.
https://doi.org/10.1158/1538-7445.AM2017-1698
Published: 01 July 2017
View articletitled, Abstract 1698: Immunoprevention of KRAS-driven lung adenocarcinoma by a multi-peptide KRAS vaccine
Journal Articles

Abstract 2367: cGMP production of a chimeric virus-like particle vaccine for prevention of HPV-associated cancers

Free
George W. Buchman, Brian P. Howard, Nadia Abdallah, Bala Medicherla, Mary Anne Fisher, Jonathan M. White, Michelle L. Kennedy, Shizuko Sei, Richard B.S. Roden, Christina Schellenbacher, Reinhard Kirnbauer, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2367.
https://doi.org/10.1158/1538-7445.AM2016-2367
Published: 15 July 2016
View articletitled, Abstract 2367: cGMP production of a chimeric virus-like particle vaccine for prevention of HPV-associated cancers
Journal Articles

Abstract 4657: Targeting STAT3 for mammary cancer prevention in MMTV/Neu mice employing the antagonist GLG-302

Free
Robert H. Shoemaker, Michael W. Lovell, John J. Whalen, Fariba Moeinpour, Clinton J. Grubbs
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4657.
https://doi.org/10.1158/1538-7445.AM2015-4657
Published: 01 August 2015
View articletitled, Abstract 4657: Targeting STAT3 for mammary cancer prevention in MMTV/Neu mice employing the antagonist GLG-302
Journal Articles

Abstract 4496: Genomics-based resistome analysis revealed endogenous adenosine kinase levels as a chief determinant of specificity for a novel nucleoside analog lymphoma inhibitor

Free
Utthara Nayar, Jonathan Reichel, Jouliana Sadek, Denise Hernandez-Hopkins, Gunkut Akar, Hufeng Zhou, Michelle A. Sahai, Peter Barelli, Ilaria Guasparri, Jennifer Totonchy, Duane Hassane, Shizuko Sei, Robert H. Shoemaker, J. David Warren, Olivier Elemento, Kenneth M. Kaye, Ethel Cesarman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4496.
https://doi.org/10.1158/1538-7445.AM2015-4496
Published: 01 August 2015
View articletitled, Abstract 4496: Genomics-based resistome analysis revealed endogenous adenosine kinase levels as a chief determinant of specificity for a novel nucleoside analog lymphoma inhibitor
Journal Articles

Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway

Free
Monika Aggarwal, Taraswi Banerjee, Joshua A. Sommers, Chiara Iannascoli, Pietro Pichierri, Robert H. Shoemaker, Robert M. Brosh, Jr.
Journal: Cancer Research
Cancer Res (2013) 73 (17): 5497–5507.
https://doi.org/10.1158/0008-5472.CAN-12-2975
Published: 02 September 2013
View articletitled, Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway
Open the PDF for Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway in another window
Includes: Supplementary data
Journal Articles

Abstract 2116: CHEK2 (Chk2) endogenous activation is associated with p53 deficiency and downregulation of BRCA2 and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60)

Free
Gabriele Zoppoli, Stéphanie Solier, William C. Reinhold, Hongfang Liu, John W. Connelly, Anne Monks, Robert H. Shoemaker, Ogan D. Abaan, Sean R. Davis, Daniela Piras, Alberto Ballestrero, Paul S. Meltzer, James H. Doroshow, Yves Pommier
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2116.
https://doi.org/10.1158/1538-7445.AM2012-2116
Published: 15 April 2012
View articletitled, Abstract 2116: CHEK2 (Chk2) endogenous activation is associated with p53 deficiency and downregulation of BRCA2 and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60)