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Robert F. Ozols
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Journal Articles

Loss of ovarian surface and cyst epithelial basement membranes and pre-neoplastic morphological changes in prophylactic oophorectomies

Isabelle H. Roland, Wan-Lin Yang, Dong-Hua Yang, Mary B. Daly, Robert F. Ozols, Thomas C. Hamilton, Henry T. Lynch, Andrew K. Godwin, Xiang-Xi Xu
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 173.
Published: 01 April 2004
View article titled, Loss of ovarian surface and cyst epithelial basement membranes and pre-neoplastic morphological changes in prophylactic oophorectomies
Journal Articles

Increased Platinum-DNA Damage Tolerance Is Associated with Cisplatin Resistance and Cross-Resistance to Various Chemotherapeutic Agents in Unrelated Human Ovarian Cancer Cell Lines

Steven W. Johnson, Paul B. Laub, Jacqueline S. Beesley, Robert F. Ozols, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1997) 57 (5): 850–856.
Published: 01 March 1997
View article titled, Increased Platinum-DNA Damage Tolerance Is Associated with Cisplatin Resistance and Cross-Resistance to Various Chemotherapeutic Agents in Unrelated Human Ovarian Cancer Cell Lines
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Journal Articles

Evidence for Altered Regulation of γ-Glutamylcysteine Synthetase Gene Expression among Cisplatin-sensitive and Cisplatin-resistant Human Ovarian Cancer Cell Lines

Kang-Shen Yao, Andrew K. Godwin, Steven W. Johnson, Robert F. Ozols, Peter J. O'Dwyer, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1995) 55 (19): 4367–4374.
Published: 01 October 1995
View article titled, Evidence for Altered Regulation of γ-Glutamylcysteine Synthetase Gene Expression among Cisplatin-sensitive and Cisplatin-resistant Human Ovarian Cancer Cell Lines
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Journal Articles

Characterization of Chromosome 9 in Human Ovarian Neoplasia Identifies Frequent Genetic Imbalance on 9q and Rare Alterations Involving 9p, Including CDKN2

David C. Schultz, Lisa Vanderveer, Kenneth H. Buetow, Matthew P. Boente, Robert F. Ozols, Thomas C. Hamilton, Andrew K. Godwin
Journal: Cancer Research
Cancer Res (1995) 55 (10): 2150–2157.
Published: 01 May 1995
View article titled, Characterization of Chromosome 9 in Human Ovarian Neoplasia Identifies Frequent Genetic Imbalance on 9q and Rare Alterations Involving 9p, Including <em>CDKN2</em>
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Journal Articles

Relationship between Platinum-DNA Adduct Formation and Removal and Cisplatin Cytotoxicity in Cisplatin-sensitive and -resistant Human Ovarian Cancer Cells

Steven W. Johnson, Pamela A. Swiggard, Laura M. Handel, James M. Brennan, Andrew K. Godwin, Robert F. Ozols, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1994) 54 (22): 5911–5916.
Published: 01 November 1994
View article titled, Relationship between Platinum-DNA Adduct Formation and Removal and Cisplatin Cytotoxicity in Cisplatin-sensitive and -resistant Human Ovarian Cancer Cells
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Journal Articles

Phase I/Pharmacokinetic Study of Topotecan by 24-Hour Continuous Infusion Weekly

Naomi B. Haas, Frank P. LaCreta, Judy Walczak, Gary R. Hudes, James M. Brennan, Robert F. Ozols, Peter J. O'Dwyer
Journal: Cancer Research
Cancer Res (1994) 54 (5): 1220–1226.
Published: 01 March 1994
View article titled, Phase I/Pharmacokinetic Study of Topotecan by 24-Hour Continuous Infusion Weekly
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Journal Articles

Phase I and Pharmacokinetic Study of Ormaplatin (Tetraplatin, NSC 363812) Administered on a Day 1 and Day 8 Schedule

Russell J. Schilder, Frank P. LaCreta, Raymond P. Perez, Steven W. Johnson, James M. Brennan, Andre Rogatko, Sherri Nash, Ceclia McAleer, Thomas C. Hamilton, David Roby, Robert C. Young, Robert F. Ozols, Peter J. O'Dwyer
Journal: Cancer Research
Cancer Res (1994) 54 (3): 709–717.
Published: 01 February 1994
View article titled, Phase I and Pharmacokinetic Study of Ormaplatin (Tetraplatin, NSC 363812) Administered on a Day 1 and Day 8 Schedule
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Journal Articles

Cross-Resistance to Diverse Drugs Is Associated with Primary Cisplatin Resistance in Ovarian Cancer Cell Lines

Kinya Hamaguchi, Andrew K. Godwin, Michiaki Yakushiji, Peter J. O'Dwyer, Robert F. Ozols, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1993) 53 (21): 5225–5232.
Published: 01 November 1993
View article titled, Cross-Resistance to Diverse Drugs Is Associated with Primary Cisplatin Resistance in Ovarian Cancer Cell Lines
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Journal Articles

Variable Baseline γ-Glutamylcysteine Synthetase Messenger RNA Expression in Peripheral Mononuclear Cells of Cancer Patients, and Its Induction by Buthionine Sulfoximine Treatment

Kang-shen Yao, Andrew K. Godwin, Robert F. Ozols, Thomas C. Hamilton, Peter J. O'Dwyer
Journal: Cancer Research
Cancer Res (1993) 53 (16): 3662–3666.
Published: 01 August 1993
View article titled, Variable Baseline γ-Glutamylcysteine Synthetase Messenger RNA Expression in Peripheral Mononuclear Cells of Cancer Patients, and Its Induction by Buthionine Sulfoximine Treatment
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Journal Articles

Phase I Study of Thiotepa in Combination with the Glutathione Transferase Inhibitor Ethacrynic Acid

Peter J. O'Dwyer, Frank LaCreta, Sherri Nash, Peter W. Tinsley, Russell Schilder, Margie L. Clapper, Kenneth D. Tew, Lisa Panting, Samuel Litwin, Robert L. Comis, Robert F. Ozols
Journal: Cancer Research
Cancer Res (1991) 51 (22): 6059–6065.
Published: 01 November 1991
View article titled, Phase I Study of Thiotepa in Combination with the Glutathione Transferase Inhibitor Ethacrynic Acid
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Journal Articles

Evaluation of Platinum-DNA Adduct Levels Relative to Known Prognostic Variables in a Cohort of Ovarian Cancer Patients

Eddie Reed, Yechiam Ostchega, Seth M. Steinberg, Stuart H. Yuspa, Robert C. Young, Robert F. Ozols, Miriam C. Poirier
Journal: Cancer Research
Cancer Res (1990) 50 (8): 2256–2260.
Published: 01 April 1990
View article titled, Evaluation of Platinum-DNA Adduct Levels Relative to Known Prognostic Variables in a Cohort of Ovarian Cancer Patients
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Journal Articles

Increased DNA Repair as a Mechanism of Acquired Resistance to cis-Diamminedichloroplatinum(II) in Human Ovarian Cancer Cell Lines

Hidetaka Masuda, Robert F. Ozols, Gi-Ming Lai, Antonio Fojo, Mace Rothenberg, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1988) 48 (20): 5713–5716.
Published: 01 October 1988
View article titled, Increased DNA Repair as a Mechanism of Acquired Resistance to <em>cis</em>-Diamminedichloroplatinum(II) in Human Ovarian Cancer Cell Lines
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Journal Articles

Antitumor Activity of an Immunotoxin in a Nude Mouse Model of Human Ovarian Cancer

David J. FitzGerald, Michael J. Bjorn, Robert J. Ferris, Jeff L. Winkelhake, Arthur E. Frankel, Thomas C. Hamilton, Robert F. Ozols, Mark C. Willingham, Ira Pastan
Journal: Cancer Research
Cancer Res (1987) 47 (5): 1407–1410.
Published: 01 March 1987
View article titled, Antitumor Activity of an Immunotoxin in a Nude Mouse Model of Human Ovarian Cancer
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Journal Articles

Characterization of a cis-Diamminedichloroplatinum(II)-resistant Human Ovarian Cancer Cell Line and Its Use in Evaluation of Platinum Analogues

Brent C. Behrens, Thomas C. Hamilton, Hidetaka Masuda, Karen R. Grotzinger, Jacqueline Whang-Peng, Karen G. Louie, Turid Knutsen, Wilma M. McKoy, Robert C. Young, Robert F. Ozols
Journal: Cancer Research
Cancer Res (1987) 47 (2): 414–418.
Published: 01 January 1987
View article titled, Characterization of a <em>cis</em>-Diamminedichloroplatinum(II)-resistant Human Ovarian Cancer Cell Line and Its Use in Evaluation of Platinum Analogues
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Journal Articles

Adoptive Cellular Immunotherapy of Human Ovarian Carcinoma Xenografts in Nude Mice

John R. Ortaldo, Hilda R. Porter, Paul Miller, Henry C. Stevenson, Robert F. Ozols, Thomas C. Hamilton
Journal: Cancer Research
Cancer Res (1986) 46 (9): 4414–4419.
Published: 01 September 1986
View article titled, Adoptive Cellular Immunotherapy of Human Ovarian Carcinoma Xenografts in Nude Mice
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Journal Articles

Radiation Survival Parameters of Antineoplastic Drug-sensitive and -resistant Human Ovarian Cancer Cell Lines and Their Modification by Buthionine Sulfoximine

Karen G. Louie, Brent C. Behrens, Timothy J. Kinsella, Thomas C. Hamilton, Karen R. Grotzinger, Wilma M. McKoy, Margaret A. Winker, Robert F. Ozols
Journal: Cancer Research
Cancer Res (1985) 45 (5): 2110–2115.
Published: 01 May 1985
View article titled, Radiation Survival Parameters of Antineoplastic Drug-sensitive and -resistant Human Ovarian Cancer Cell Lines and Their Modification by Buthionine Sulfoximine
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Journal Articles

Anti-Transferrin Receptor Antibody Linked to Pseudomonas Exotoxin as a Model Immunotoxin in Human Ovarian Carcinoma Cell Lines

Robert Pirker, David J. P. FitzGerald, Thomas C. Hamilton, Robert F. Ozols, Mark C. Willingham, Ira Pastan
Journal: Cancer Research
Cancer Res (1985) 45 (2): 751–757.
Published: 01 February 1985
View article titled, Anti-Transferrin Receptor Antibody Linked to <em>Pseudomonas</em> Exotoxin as a Model Immunotoxin in Human Ovarian Carcinoma Cell Lines
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Journal Articles

Characterization of a Xenograft Model of Human Ovarian Carcinoma Which Produces Ascites and Intraabdominal Carcinomatosis in Mice

Thomas C. Hamilton, Robert C. Young, Karen G. Louie, Brent C. Behrens, Wilma M. McKoy, Karen R. Grotzinger, Robert F. Ozols
Journal: Cancer Research
Cancer Res (1984) 44 (11): 5286–5290.
Published: 01 November 1984
View article titled, Characterization of a Xenograft Model of Human Ovarian Carcinoma Which Produces Ascites and Intraabdominal Carcinomatosis in Mice
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Journal Articles

Characterization of a Human Ovarian Carcinoma Cell Line (NIH:OVCAR-3) with Androgen and Estrogen Receptors

Thomas C. Hamilton, Robert C. Young, Wilma M. McKoy, Karen R. Grotzinger, John A. Green, Elizabeth W. Chu, Jacqueline Whang-Peng, Alfred M. Rogan, William R. Green, Robert F. Ozols
Journal: Cancer Research
Cancer Res (1983) 43 (11): 5379–5389.
Published: 01 November 1983
View article titled, Characterization of a Human Ovarian Carcinoma Cell Line (NIH:OVCAR-3) with Androgen and Estrogen Receptors
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Journal Articles

A Phase I and Pharmacokinetic Study of Diamminecyclobutanedicarboxylatoplatinum (NSC 241240)

Gregory A. Curt, John J. Grygiel, Brian J. Corden, Robert F. Ozols, Raymond B. Weiss, Daniel T. Tell, Charles E. Myers, Jerry M. Collins
Journal: Cancer Research
Cancer Res (1983) 43 (9): 4470–4473.
Published: 01 September 1983
View article titled, A Phase I and Pharmacokinetic Study of Diamminecyclobutanedicarboxylatoplatinum (NSC 241240)
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