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Robert A. Newman
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Journal Articles

Abstract 4658: Use of a defined oleander extract by advanced cancer patients: Case reports on toxicity and tumor-related outcomes

Keith I. Block, Charlotte Gyllenhaal, Robert A. Newman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4658.
https://doi.org/10.1158/1538-7445.AM2014-4658
Published: 01 October 2014
View article titled, Abstract 4658: Use of a defined oleander extract by advanced cancer patients: Case reports on toxicity and tumor-related outcomes
Journal Articles

Abstract 5554: PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down-regulation of PI3k/mTOR pathways.

Yong Pan, Sun-Jin Kim, Patrea Rhea, Carrie Cartwright, Ho Jeong Lee, Crandell Addington, Mihai Gagea, Robert A. Newman, Peiying Yang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5554.
https://doi.org/10.1158/1538-7445.AM2013-5554
Published: 15 April 2013
View article titled, Abstract 5554: PBI-05204, a supercritical CO<sub>2</sub> extract of <em>Nerium oleander</em>, inhibits the growth of human pancreatic cancer in a Panc-1 orthotopic model by down-regulation of PI3k/mTOR pathways.
Journal Articles

Abstract LB-177: A supercritical turmeric extract prevents small intestinal and colonic tumors in the APCMin/+ mice by suppressing proliferation and cancer stem cell markers

Venkateshwar Madka, Altaf Mohammed, Laura Biddick, Yuting Zhang, Robert A. Newman, Bharat B. Aggarwal, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-177.
https://doi.org/10.1158/1538-7445.AM2012-LB-177
Published: 15 April 2012
View article titled, Abstract LB-177: A supercritical turmeric extract prevents small intestinal and colonic tumors in the APC<sup>Min/+</sup> mice by suppressing proliferation and cancer stem cell markers
Journal Articles

Abstract 2897: Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis

Imad Shureiqi, Dongning Chen, R. Sue Day, Xiangsheng Zuo, William Ross, Ofir Moy, Jeffrey Scott Morris, Lianchun Xiao, Robert A. Newman, Peiying Yang, Scott M. Lippman
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2897.
https://doi.org/10.1158/1538-7445.AM10-2897
Published: 15 April 2010
View article titled, Abstract 2897: Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis
Journal Articles

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

Qian Jia, Joanne R. Lupton, Roger Smith, Brad R. Weeks, Evelyn Callaway, Laurie A. Davidson, Wooki Kim, Yang-Yi Fan, Peiying Yang, Robert A. Newman, Jing X. Kang, David N. McMurray, Robert S. Chapkin
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3985–3991.
https://doi.org/10.1158/0008-5472.CAN-07-6251
Published: 15 May 2008
View article titled, Reduced Colitis-Associated Colon Cancer in <em>Fat-1</em> (<em>n</em>-3 Fatty Acid Desaturase) Transgenic Mice
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Includes: Supplementary data
Journal Articles

15-lipoxygenase-1 induction of terminal differentiation and apoptosis in human colonic epithelial cells

Yuanqing Wu, Dongning Chen, Xiu L. Yang, Baoxiang Guan, Jeffrey S. Morris, Peiying Yang, Robert A. Newman, Scott M. Lippman, Imad Shureiqi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1157.
Published: 15 April 2006
View article titled, 15-lipoxygenase-1 induction of terminal differentiation and apoptosis in human colonic epithelial cells
Journal Articles

Anti-proliferative activity of Huachansu, a Bufo toad skin extract, against human malignant melanoma cells

Peiying Yang, Diana Chan, Mary Vijjeswarapu, Carrie Cartwright, Lorenzo Cohen, Zhiqiang Meng, Luming Liu, Robert A. Newman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 906.
Published: 15 April 2006
View article titled, Anti-proliferative activity of Huachansu, a Bufo toad skin extract, against human malignant melanoma cells
Journal Articles

Antitumor activity of fish oils in human lung cancer is associated with altered formation of PGE2 and PGE3

Peiying Yang, Diana Chan, Edward Felix, Timothy Madden, Yiling Lu, Keith I. Block, Robert A. Newman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 749.
Published: 15 April 2006
View article titled, Antitumor activity of fish oils in human lung cancer is associated with altered formation of PGE<sub>2</sub> and PGE<sub>3</sub>
Journal Articles

The Critical Role of 15-Lipoxygenase-1 in Colorectal Epithelial Cell Terminal Differentiation and Tumorigenesis

Imad Shureiqi, Yuanqing Wu, Dongning Chen, Xiu L. Yang, Baoxiang Guan, Jeffrey S. Morris, Peiying Yang, Robert A. Newman, Russell Broaddus, Stanley R. Hamilton, Patrick Lynch, Bernard Levin, Susan M. Fischer, Scott M. Lippman
Journal: Cancer Research
Cancer Res (2005) 65 (24): 11486–11492.
https://doi.org/10.1158/0008-5472.CAN-05-2180
Published: 15 December 2005
View article titled, The Critical Role of 15-Lipoxygenase-1 in Colorectal Epithelial Cell Terminal Differentiation and Tumorigenesis
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Journal Articles

HER2/neu-Induced Mammary Tumorigenesis and Angiogenesis Are Reduced in Cyclooxygenase-2 Knockout Mice

Louise R. Howe, Sung-Hee Chang, Kelly C. Tolle, Rachelle Dillon, Lawrence J.T. Young, Robert D. Cardiff, Robert A. Newman, Peiying Yang, Howard T. Thaler, William J. Muller, Clifford Hudis, Anthony M.C. Brown, Timothy Hla, Kotha Subbaramaiah, Andrew J. Dannenberg
Journal: Cancer Research
Cancer Res (2005) 65 (21): 10113–10119.
https://doi.org/10.1158/0008-5472.CAN-05-1524
Published: 01 November 2005
View article titled, HER2/neu-Induced Mammary Tumorigenesis and Angiogenesis Are Reduced in Cyclooxygenase-2 Knockout Mice
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Journal Articles

Activation of Protein Kinase G Up-regulates Expression of 15-Lipoxygenase-1 in Human Colon Cancer Cells

Atsuko Deguchi, Steven W. Xing, Imad Shureiqi, Peiying Yang, Robert A. Newman, Scott M. Lippman, Steven J. Feinmark, Bert Oehlen, I. Bernard Weinstein
Journal: Cancer Research
Cancer Res (2005) 65 (18): 8442–8447.
https://doi.org/10.1158/0008-5472.CAN-05-1109
Published: 15 September 2005
View article titled, Activation of Protein Kinase G Up-regulates Expression of 15-Lipoxygenase-1 in Human Colon Cancer Cells
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Journal Articles

Suppression of Prostate Tumor Cell Growth by Stromal Cell Prostaglandin D Synthase–Derived Products

Jeri Kim, Peiying Yang, Milind Suraokar, Anita L. Sabichi, Norma D. Llansa, Gabriela Mendoza, Vemparalla Subbarayan, Christopher J. Logothetis, Robert A. Newman, Scott M. Lippman, David G. Menter
Journal: Cancer Research
Cancer Res (2005) 65 (14): 6189–6198.
https://doi.org/10.1158/0008-5472.CAN-04-4439
Published: 15 July 2005
View article titled, Suppression of Prostate Tumor Cell Growth by Stromal Cell Prostaglandin D Synthase–Derived Products
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Journal Articles

Prostate stromal prostaglandin D2 synthase-derived eicosanoid products suppress prostate cancer cell growth

Jeri Kim, Peiying Yang, Anita L. Sabichi, Funda Vakar-Lopez, Norma Llansa, Gabriella Mendosa, Robert A. Newman, Scott M. Lippman, David G. Menter
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 200.
Published: 01 April 2004
View article titled, Prostate stromal prostaglandin D<sub>2</sub> synthase-derived eicosanoid products suppress prostate cancer cell growth
Journal Articles

Inhibition of the growth and induction of apoptosis in head and neck squamous cell carcinoma cells by celecoxib

Claudia P. Schroeder, Peiying Yang, Robert A. Newman, Reuben Lotan
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1227.
Published: 01 April 2004
View article titled, Inhibition of the growth and induction of apoptosis in head and neck squamous cell carcinoma cells by celecoxib
Journal Articles

Novel anticancer compounds derived from branched chain fatty acids: Development and characterization of D82.

Robert A. Newman, Peiying Yang, Diana Chan, Helen Huang, Xudong Chen, Shoutie Yu, Zhenhua Yang, Warren S. Liao
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 473.
Published: 01 April 2004
View article titled, Novel anticancer compounds derived from branched chain fatty acids: Development and characterization of D82.
Journal Articles

Celecoxib inhibits prostate cancer growth. Evidence of a COX-2-independent mechanism

Manish I. Patel, Kotha Subbaramaiah, Baoheng Du, Mindy Chang, Peiying Yang, Robert A. Newman, Carlos Cordon-Cardo, Howard T. Thaler, Andrew J. Dannenberg
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 920.
Published: 01 April 2004
View article titled, Celecoxib inhibits prostate cancer growth. Evidence of a COX-2-independent mechanism
Journal Articles

An LC/MS/MS based method to analyze tissue eicosanoids: Application to EPA-mediated alteration of prostaglandin metabolism

Peiying Yang, Russell D. Klein, Edward Felix, Diana Chan, Timothy Madden, Robert A. Newman
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 902.
Published: 01 April 2004
View article titled, An LC/MS/MS based method to analyze tissue eicosanoids: Application to EPA-mediated alteration of prostaglandin metabolism
Journal Articles

Celecoxib treatment reduces tumor growth in the TRAMP model of prostate cancer

Russell D. Klein, Jennifer K. Colby, Peiying Yang, Robert A. Newman, Susan M. Fischer
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 935.
Published: 01 April 2004
View article titled, Celecoxib treatment reduces tumor growth in the TRAMP model of prostate cancer
Journal Articles

The Human Lipid Phosphate Phosphatase-3 Decreases the Growth, Survival, and Tumorigenesis of Ovarian Cancer Cells: Validation of the Lysophosphatidic Acid Signaling Cascade as a Target for Therapy in Ovarian Cancer

Janos L. Tanyi, Andrew J. Morris, Judith K. Wolf, Xianjun Fang, Yutaka Hasegawa, Ruth Lapushin, Nelly Auersperg, Yury J. Sigal, Robert A. Newman, Edward A. Felix, Edward N. Atkinson, Gordon B. Mills
Journal: Cancer Research
Cancer Res (2003) 63 (5): 1073–1082.
Published: 01 March 2003
View article titled, The Human Lipid Phosphate Phosphatase-3 Decreases the Growth, Survival, and Tumorigenesis of Ovarian Cancer Cells: <subtitle>Validation of the Lysophosphatidic Acid Signaling Cascade as a Target for Therapy in Ovarian Cancer</subtitle>
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Journal Articles

8-Chloro-cAMP and 8-Chloro-adenosine Act by the Same Mechanism in Multiple Myeloma Cells

Varsha Gandhi, Mary Ayres, Robert G. Halgren, Nancy L. Krett, Robert A. Newman, Steve T. Rosen
Journal: Cancer Research
Cancer Res (2001) 61 (14): 5474–5479.
Published: 01 July 2001
View article titled, 8-Chloro-cAMP and 8-Chloro-adenosine Act by the Same Mechanism in Multiple Myeloma Cells
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