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Robert A. Gatenby
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Journal Articles

Abstract 2672: Eco-evolutionary profiling of the UV-driven clonal dynamics and tumor initiation

Free
Stanislav S. Avdieiev, Leticia Tordesillas, Karol Prieto, Omar Chavez Chiang, Zhihua Chen, Nihir Patel, Sofia Cordero, Luiza Silva Simoes, Y. Ann Chen, Noemi Andor, Robert A. Gatenby, Elsa R. Flores, Christopher J. Whelan, Joel S. Brown, Kenneth Y. Tsai
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2672.
https://doi.org/10.1158/1538-7445.AM2025-2672
Published: 21 April 2025
View articletitled, Abstract 2672: Eco-evolutionary profiling of the UV-driven clonal dynamics and tumor initiation
Journal Articles

Abstract 3696: Evolutionary immunotherapy in NSCLC: identifying optimal dosing strategies in TIL therapy using agent-based modeling

Free
Sandhya Prabhakaran, Mark Robertson-Tessi, Kimberly Luddy, Rafael R. Bravo, Taylor M. Bursell, Julian Pineiro, Jeffrey West, Megan Johnson, Jhanelle A. Gray, Amer A. Beg, Scott J. Antonia, Robert A. Gatenby, Alexander R. Anderson
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3696.
https://doi.org/10.1158/1538-7445.AM2025-3696
Published: 21 April 2025
View articletitled, Abstract 3696: Evolutionary immunotherapy in NSCLC: identifying optimal dosing strategies in TIL therapy using agent-based modeling
Journal Articles

The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma

Open Access
Praneeth Reddy Sudalagunta, Rafael R. Canevarolo, Mark B. Meads, Maria Silva, Xiaohong Zhao, Christopher L. Cubitt, Samer S. Sansil, Gabriel DeAvila, Raghunandan Reddy Alugubelli, Ryan T. Bishop, Alexandre Tungesvik, Qi Zhang, Oliver Hampton, Jamie K. Teer, Eric A. Welsh, Sean J. Yoder, Bijal D. Shah, Lori Hazlehurst, Robert A. Gatenby, Dane R. Van Domelen, Yi Chai, Feng Wang, Andrew DeCastro, Amanda M. Bloomer, Erin M. Siegel, Conor C. Lynch, Daniel M. Sullivan, Melissa Alsina, Taiga Nishihori, Jason Brayer, John L. Cleveland, William Dalton, Christopher J. Walker, Yosef Landesman, Rachid Baz, Ariosto S. Silva, Kenneth H. Shain
Journal: Cancer Research
Cancer Res (2025) 85 (2): 378–398.
https://doi.org/10.1158/0008-5472.CAN-24-0886
Published: 15 January 2025
View articletitled, The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy

Open Access
Kit Gallagher, Maximilian A.R. Strobl, Derek S. Park, Fabian C. Spoendlin, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2025) 85 (2): 399.
https://doi.org/10.1158/0008-5472.CAN-24-4438
Published: 15 January 2025
View articletitled, Correction: Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy
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Journal Articles

Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy

Open Access
Kit Gallagher, Maximilian A.R. Strobl, Derek S. Park, Fabian C. Spoendlin, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (11): 1929–1941.
https://doi.org/10.1158/0008-5472.CAN-23-2040
Published: 04 June 2024
View articletitled, Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy
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Includes: Supplementary data
Journal Articles

Abstract A021: Evolutionary immunotherapy in NSCLC: An integrated approach

Free
Sandhya Prabhakaran, Taylor M. Bursell, Kimberly Luddy, Julian Pineiro, Rafael Bravo, Jeffrey West, Megan Johnson, Mark Robertson-Tessi, Amer A. Beg, Jhanelle E. Gray, Scott Antonia, Robert A. Gatenby, Alexander R. A. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_2): A021.
https://doi.org/10.1158/1538-7445.CANEVOL23-A021
Published: 01 February 2024
View articletitled, Abstract A021: Evolutionary immunotherapy in NSCLC: An integrated approach
Journal Articles

Abstract SY29-01: Integrating evolutionary dynamics into cancer therapy

Free
Robert A. Gatenby
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): SY29-01.
https://doi.org/10.1158/1538-7445.AM2023-SY29-01
Published: 04 April 2023
View articletitled, Abstract SY29-01: Integrating evolutionary dynamics into cancer therapy
Journal Articles

Abstract 132: The molecular basis of an evolutionary arms race between cancer cells and their host

Free
Arig A. Ibrahim-Hashim, Robert A. Gatenby, Christina L. Richards, Joel S. Brown
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 132.
https://doi.org/10.1158/1538-7445.AM2023-132
Published: 04 April 2023
View articletitled, Abstract 132: The molecular basis of an evolutionary arms race between cancer cells and their host
Journal Articles

Abstract 5037: Distinct tumor-immune ecologies in NSCLC patients predict progression and define a clinical biomarker of therapy response

Free
Sandhya Prabhakaran, Chandler Gatenbee, Mark Robertson-Tessi, Amer A. Beg, Jhanelle Gray, Scott Antonia, Robert A. Gatenby, Alexander R. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5037.
https://doi.org/10.1158/1538-7445.AM2022-5037
Published: 15 June 2022
View articletitled, Abstract 5037: Distinct tumor-immune ecologies in NSCLC patients predict progression and define a clinical biomarker of therapy response
Journal Articles

Abstract B020: Distinct spatiotemporal tumor-immune ecologies enable disease prediction in NSCLC patients

Free
Sandhya Prabhakaran, Chandler Gatenbee, Mark Robertson-Tessi, Amer A. Beg, Jhanelle Gray, Scott Antonia, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): B020.
https://doi.org/10.1158/1538-7445.EVODYN22-B020
Published: 15 May 2022
View articletitled, Abstract B020: Distinct spatiotemporal tumor-immune ecologies enable disease prediction in NSCLC patients
Journal Articles

Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer

Available to Purchase
Asmaa El-Kenawi, William Dominguez-Viqueira, Min Liu, Shivanshu Awasthi, Julieta Abraham-Miranda, Aysenur Keske, KayLee K. Steiner, Leenil Noel, Amparo N. Serna, Jasreman Dhillon, Robert J. Gillies, Xiaoqing Yu, John M. Koomen, Kosj Yamoah, Robert A. Gatenby, Brian Ruffell
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5477–5490.
https://doi.org/10.1158/0008-5472.CAN-20-4028
Published: 01 November 2021
View articletitled, Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy

Available to Purchase
Maximilian A.R. Strobl, Jeffrey West, Yannick Viossat, Mehdi Damaghi, Mark Robertson-Tessi, Joel S. Brown, Robert A. Gatenby, Philip K. Maini, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2021) 81 (4): 1135–1147.
https://doi.org/10.1158/0008-5472.CAN-20-0806
Published: 15 February 2021
View articletitled, Turnover Modulates the Need for a Cost of Resistance in Adaptive Therapy
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Includes: Supplementary data
Journal Articles

Searching for Goldilocks: How Evolution and Ecology Can Help Uncover More Effective Patient-Specific Chemotherapies

Available to Purchase
Derek S. Park, Kimberly A. Luddy, Mark Robertson-Tessi, Cliona O'Farrelly, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5147–5154.
https://doi.org/10.1158/0008-5472.CAN-19-3981
Published: 02 December 2020
View articletitled, Searching for Goldilocks: How Evolution and Ecology Can Help Uncover More Effective Patient-Specific Chemotherapies
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Journal Articles

Towards Multidrug Adaptive Therapy

Available to Purchase
Jeffrey West, Li You, Jingsong Zhang, Robert A. Gatenby, Joel S. Brown, Paul K. Newton, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1578–1589.
https://doi.org/10.1158/0008-5472.CAN-19-2669
Published: 02 April 2020
View articletitled, Towards Multidrug Adaptive Therapy
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Includes: Supplementary data
Journal Articles

Eradicating Metastatic Cancer and the Eco-Evolutionary Dynamics of Anthropocene Extinctions

Available to Purchase
Robert A. Gatenby, Yael Artzy-Randrup, Tamir Epstein, Damon R. Reed, Joel S. Brown
Journal: Cancer Research
Cancer Res (2020) 80 (3): 613–623.
https://doi.org/10.1158/0008-5472.CAN-19-1941
Published: 03 February 2020
View articletitled, Eradicating Metastatic Cancer and the Eco-Evolutionary Dynamics of Anthropocene Extinctions
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Journal Articles

The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right

Available to Purchase
Derek S. Park, Mark Robertson-Tessi, Kimberly A. Luddy, Philip K. Maini, Michael B. Bonsall, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2019) 79 (20): 5302–5315.
https://doi.org/10.1158/0008-5472.CAN-18-3712
Published: 15 October 2019
View articletitled, The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right
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Includes: Supplementary data
Journal Articles

Abstract SY36-02: Exploiting evolutionary dynamics in optimizing cancer treatment

Free
Robert A. Gatenby
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): SY36-02.
https://doi.org/10.1158/1538-7445.AM2019-SY36-02
Published: 01 July 2019
View articletitled, Abstract SY36-02: Exploiting evolutionary dynamics in optimizing cancer treatment
Journal Articles

First Strike–Second Strike Strategies in Metastatic Cancer: Lessons from the Evolutionary Dynamics of Extinction

Available to Purchase
Robert A. Gatenby, Jingsong Zhang, Joel S. Brown
Journal: Cancer Research
Cancer Res (2019) 79 (13): 3174–3177.
https://doi.org/10.1158/0008-5472.CAN-19-0807
Published: 01 July 2019
View articletitled, First Strike–Second Strike Strategies in Metastatic Cancer: Lessons from the Evolutionary Dynamics of Extinction
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Journal Articles

The Physics of Cancer

Available to Purchase
Forest M. White, Robert A. Gatenby, Claudia Fischbach
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2107–2110.
https://doi.org/10.1158/0008-5472.CAN-18-3937
Published: 01 May 2019
View articletitled, The Physics of Cancer
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Journal Articles

Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies

Available to Purchase
Jill A. Gallaher, Pedro M. Enriquez-Navas, Kimberly A. Luddy, Robert A. Gatenby, Alexander R.A. Anderson
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2127–2139.
https://doi.org/10.1158/0008-5472.CAN-17-2649
Published: 12 April 2018
View articletitled, Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies
Open the PDF for Spatial Heterogeneity and Evolutionary Dynamics Modulate Time to Recurrence in Continuous and Adaptive Cancer Therapies in another window
Includes: Multimedia, Supplementary data